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    • 9. 发明授权
    • Artificial pyramid
    • 人造金字塔
    • US06887272B2
    • 2005-05-03
    • US10468010
    • 2002-02-20
    • Kenichi ShinomiyaSoichiro ItohJunzo TanakaMasanori Kikuchi
    • Kenichi ShinomiyaSoichiro ItohJunzo TanakaMasanori Kikuchi
    • A61L27/00A61B17/80A61F2/44A61L27/46A61L27/58A61F2/28A61F13/00
    • A61L27/56A61B17/80A61F2/44A61L27/46A61L2430/38C08L89/06
    • Disclosed is an artificial vertebra having a bone-marrow regenerating function, comprising a hydroxyapatite (HAp)/collagen (Col) composite body formed by pressure-dehydrating a coprecipitate of hydroxyapatite and collagen to have a nanocomposite structure in which HAp particles are conjugated along a Col fiber while aligned each of the c-axes of the HAp particles along the Col fiber. The HAp/Col composite body is formed with a perforated aperture for allowing a blood vessel and an osteogenic cell to intrude thereinto. The present invention also provides a biodecomposable/bioabsorbable support for fixing an artificial vertebra, comprising a polylactic acid plate prepared by injection-molding molten polylactic acid and then extrusion-molding the injection-molded polylactic acid in such a manner that it is draw-oriented in a uniaxial direction. The plate has four corner regions each formed with a screw hole for fixing the plate to vertebral bodies.
    • 公开了一种具有骨髓再生功能的人造椎骨,其包含羟磷灰石(HAp)/胶原(Col)复合体,其通过将羟基磷灰石和胶原的共沉淀物进行压力脱水而形成,以具有纳米复合结构,其中HAp颗粒沿着 Col纤维同时沿着Col纤维排列HAp颗粒的每个c轴。 HAp / Col复合体形成有穿孔,用于允许血管和成骨细胞侵入其中。 本发明还提供了一种用于固定人造椎骨的生物可组合/生物吸收性支撑体,其包括通过注射熔融聚乳酸制备的聚乳酸板,然后以注射成型聚乳酸的方式使其成为拉伸取向 在单轴方向。 该板具有四个拐角区域,每个角部区域形成有用于将板固定到椎体的螺钉孔。
    • 10. 发明申请
    • Alternate soaking apparatus and method for treatment of tissue materials
    • 替代浸泡装置和组织材料处理方法
    • US20050053671A1
    • 2005-03-10
    • US10927054
    • 2004-08-27
    • Junzo TanakaMasataka SakaneHironobu FukuzakiYoshikane YokoyamaKunihiro OtaMasanori KikuchiToshiyuki IkomaIsamu Yamaguchi
    • Junzo TanakaMasataka SakaneHironobu FukuzakiYoshikane YokoyamaKunihiro OtaMasanori KikuchiToshiyuki IkomaIsamu Yamaguchi
    • A61L27/32A61L27/36A61K33/42
    • A61L27/3683A61L27/32A61L2430/40
    • The alternate soaking apparatus for treatment of tissue materials has a plurality of chemical liquid containers, a treatment container for soaking and treating a tissue material, a plurality of liquid feed tubes for providing fluid communication between the corresponding chemical liquid containers and the treatment container to introduce the respective chemical liquids into the treatment container, a liquid discharge tube for discharging the chemical liquids in the treatment container, and control means for controllably opening and closing the liquid feed tubes and the liquid discharge tube to allow the plurality of chemical liquids to be contained in the treatment container individually and alternately. A tissue material is treated using the above alternate soaking apparatus under the condition that one of chemical liquids is an aqueous solution containing calcium, and another one of chemical liquids is an aqueous solution containing phosphoric acid, so as to form a calcium phosphate compound on the surface of and in the inside of the treated tissue material. The present invention allows a ligament material and to be automatically synthesized with a calcium phosphate-based compound in a shorter time-period by a limited number of members during the operation while securing an aseptic condition.
    • 用于处理组织材料的替代浸泡装置具有多个化学液体容器,用于浸泡和处理组织材料的处理容器,用于在相应的化学液体容器和处理容器之间提供流体连通的多个液体进料管以引入 进入处理容器的各化学液体,用于排出处理容器中的化学液体的液体排出管,以及用于可控地打开和关闭液体进料管和液体排出管以允许容纳多种化学液体的控制装置 在处理容器中单独地和交替地。 使用上述替代均热装置在化学液体是含有钙的水溶液的条件下处理组织材料,另一种化学液体是含有磷酸的水溶液,以便在其上形成磷酸钙化合物 处理过的组织材料的表面和内部。 本发明允许韧带材料,并且在确保无菌条件的同时在操作期间由有限数量的构件在较短的时间段内以磷酸钙基化合物自动合成。