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1. 发明申请

US20050053671A1 Alternate soaking apparatus and method for treatment of tissue materials 审中-公开
标题翻译：替代浸泡装置和组织材料处理方法
公开(公告)号：US20050053671A1
公开(公告)日：2005-03-10
申请号：US10927054
申请日：2004-08-27
申请人： Junzo Tanaka , Masataka Sakane , Hironobu Fukuzaki , Yoshikane Yokoyama , Kunihiro Ota , Masanori Kikuchi , Toshiyuki Ikoma , Isamu Yamaguchi
发明人： Junzo Tanaka , Masataka Sakane , Hironobu Fukuzaki , Yoshikane Yokoyama , Kunihiro Ota , Masanori Kikuchi , Toshiyuki Ikoma , Isamu Yamaguchi
IPC分类号： A61L27/32 , A61L27/36 , A61K33/42
CPC分类号： A61L27/3683 , A61L27/32 , A61L2430/40
摘要： The alternate soaking apparatus for treatment of tissue materials has a plurality of chemical liquid containers, a treatment container for soaking and treating a tissue material, a plurality of liquid feed tubes for providing fluid communication between the corresponding chemical liquid containers and the treatment container to introduce the respective chemical liquids into the treatment container, a liquid discharge tube for discharging the chemical liquids in the treatment container, and control means for controllably opening and closing the liquid feed tubes and the liquid discharge tube to allow the plurality of chemical liquids to be contained in the treatment container individually and alternately. A tissue material is treated using the above alternate soaking apparatus under the condition that one of chemical liquids is an aqueous solution containing calcium, and another one of chemical liquids is an aqueous solution containing phosphoric acid, so as to form a calcium phosphate compound on the surface of and in the inside of the treated tissue material. The present invention allows a ligament material and to be automatically synthesized with a calcium phosphate-based compound in a shorter time-period by a limited number of members during the operation while securing an aseptic condition.
摘要翻译：用于处理组织材料的替代浸泡装置具有多个化学液体容器，用于浸泡和处理组织材料的处理容器，用于在相应的化学液体容器和处理容器之间提供流体连通的多个液体进料管以引入进入处理容器的各化学液体，用于排出处理容器中的化学液体的液体排出管，以及用于可控地打开和关闭液体进料管和液体排出管以允许容纳多种化学液体的控制装置在处理容器中单独地和交替地。使用上述替代均热装置在化学液体是含有钙的水溶液的条件下处理组织材料，另一种化学液体是含有磷酸的水溶液，以便在其上形成磷酸钙化合物处理过的组织材料的表面和内部。本发明允许韧带材料，并且在确保无菌条件的同时在操作期间由有限数量的构件在较短的时间段内以磷酸钙基化合物自动合成。

2. 发明授权

US4375523A Curable silicone elastomer composition 失效
标题翻译：可固化有机硅弹性体组合物
公开(公告)号：US4375523A
公开(公告)日：1983-03-01
申请号：US286069
申请日：1981-07-23
申请人： Masayuki Hatanaka , Atsushi Kurita , Yoshikane Yokoyama , Masahiro Kusakabe
发明人： Masayuki Hatanaka , Atsushi Kurita , Yoshikane Yokoyama , Masahiro Kusakabe
IPC分类号： C08L83/00 , A61L31/00 , A61M1/00 , B25J7/00 , C08K3/00 , C08K3/14 , C08K13/02 , C08L83/04 , C08L83/07 , H01B3/46 , C08K9/06
CPC分类号： C08L83/04 , B25J7/00 , C08K3/14 , C08G77/12 , C08G77/20
摘要： There is provided herein a curable silicone elastomer composition comprising the following components: (A) 100 parts by weight of a polyorganosiloxane having at least two silicon-bonded vinyl groups per molecule, (B) 1 to 300 parts by weight of fine powders of tungsten carbide and (C) a component for crosslinking of said component (A) selected from the group consisting of (1) a combination of (a) 0.1 to 10 parts by weight of a polyorganohydrogensiloxane having an average of at least two silicon-bonded hydrogen atoms per molecule and (b) 0.000001 to 0.1 part by weight of a platinum catalyst; (2) a combination of said (a), (b) and (c) 0.00001 part to less than 0.1 part by weight of an organic peroxide except from organohydroperoxide; (3) a combination of said (a) and (d) 0.00001 part to less than 0.2 part by weight of the reaction product between said (b) and (c); and (4) 0.1 to 3.0 parts by weight of an organic peroxide except from organohydroperoxide. The composition according to the present invention shows excellent X-xay shielding effect as well as excellent anticoagulative effect, and can give an elastomer of high quality by curing with a broad scope of catalyst systems.
摘要翻译：本文提供了可固化的硅氧烷弹性体组合物，其包含以下组分：（A）每分子100重量份具有至少两个与硅键合的乙烯基的聚有机硅氧烷，（B）1至300重量份的钨粉末碳化物和（C）用于交联所述组分（A）的组分，所述组分选自（1）（a）0.1至10重量份平均具有至少两个与硅键合的氢的聚有机氢硅氧烷的组合（b）0.000001至0.1重量份的铂催化剂; （2）所述（a），（b）和（c）0.00001至小于0.1重量份的有机过氧化物除了有机过氧化氢之外的组合; （3）所述（a）和（d）0.00001至小于0.2重量份所述（b）和（c）之间的反应产物的组合; 和（4）除了有机过氧化氢之外的有机过氧化物为0.1〜3.0重量份。根据本发明的组合物显示出优异的X射线屏蔽效果以及优异的抗凝效果，并且可以通过广泛的催化剂体系固化而得到高质量的弹性体。

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