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1. 发明专利

IL211718D0 PLICATION DEVICE WITH FORMABLE LINEAR FASTENER FOR USE IN THE DIRECT PLICATION ANNULOPLASTY TREATMENT OF MITRAL VALVE REGURGITATION 未知
公开(公告)号：IL211718D0
公开(公告)日：2011-06-30
申请号：IL21171811
申请日：2011-03-14
申请人： CORDIS CORP , MATTHEW KREVER , RUDOLPH CEDRO JR , TIMOTHY LASH , DAVID MAJERCAK , DANIEL H OLSEN
IPC分类号： A61B20060101

2. 发明申请

US20080147001A1 Rapid-exchange balloon catheter shaft and method 有权
标题翻译：快速交换球囊导管轴和方法
公开(公告)号：US20080147001A1
公开(公告)日：2008-06-19
申请号：US12008509
申请日：2008-01-11
申请人： Laila Al-Marashi , David Grewe , Stephen Griffin , Elaine Lim , David Majercak , Roger Stevens
发明人： Laila Al-Marashi , David Grewe , Stephen Griffin , Elaine Lim , David Majercak , Roger Stevens
IPC分类号： A61M25/10 , A61F2/84
CPC分类号： A61M25/10 , A61F2/915 , A61F2/958 , A61F2002/91558 , A61F2230/0054 , A61F2250/0018 , A61M25/0054 , A61M2025/0183
摘要： A balloon catheter or stent delivery system for medical treatment of a patient has a proximal hub, a balloon, and an improved shaft design. The catheter shaft has a rapid-exchange configuration, and a tubular outer body that includes a hypotube extending from the catheter proximal end to a position at or near a proximal leg of the balloon. An inner tubular body defines a guidewire lumen extending from a distal guidewire port at the catheter distal end to a proximal port located at a position between the balloon and the hub. A distal leg of the balloon is directly or indirectly affixed to the inner body, and a proximal leg of the balloon is affixed to the distal end of the outer body. The hypotube has an aperture for accepting the inner body proximal end, and a circumferential cut pattern. The cut pattern adds flexibility, and may extend from the hypotube distal end to a position proximal of the proximal guidewire port. The cut pattern may have any desired shape, including a spiral, a helical undulating path, or an overlapping serpentine path with inflection points, for example. The hypotube has a fluid-tight covering such as a heat-shrink polymer, so the outer body supports pressure of an inflation medium. The proximal guidewire port may be positioned on or between the individual portions of the cut pattern, or at a position beyond the cut pattern.
摘要翻译：用于患者医疗的球囊导管或支架输送系统具有近端毂，球囊和改进的轴设计。导管轴具有快速交换构造，以及管状外体，其包括从导管近端延伸到球囊的近端腿处或附近的位置的海波管。内部管状体限定从导管远端处的远端导丝端口延伸到位于气囊和轮毂之间的位置的近端口的导丝管腔。球囊的远端腿直接或间接地固定到内体上，并且气球的近端腿固定到外体的远端。海波管具有用于接纳内体近端的孔和圆周切割图案。切割图案增加了柔性，并且可以从海波管远端延伸到近端导丝端口的近端。切割图案可以具有任何期望的形状，例如包括螺旋形，螺旋形起伏路径或具有拐点的重叠蛇形路径。海波管具有流体密封的覆盖物，例如热收缩聚合物，因此外壳支撑膨胀介质的压力。近端导丝端口可以定位在切割图案的各个部分之间或之间，或位于切割图案之外的位置。

3. 发明申请

US20060025846A1 AAA low profile support structure 有权
标题翻译： AAA低调支持结构
公开(公告)号：US20060025846A1
公开(公告)日：2006-02-02
申请号：US11188498
申请日：2005-07-25
申请人： Frederick Feller , David Majercak , Jin Park , Diana Sanchez
发明人： Frederick Feller , David Majercak , Jin Park , Diana Sanchez
IPC分类号： A61F2/90
CPC分类号： A61F2/856 , A61F2/07 , A61F2/89 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2002/065 , A61F2002/075 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2220/0016 , A61F2220/0066 , A61F2220/0075 , A61F2230/0054 , A61F2230/0067 , A61F2250/0037
摘要： An endoprosthesis for repairing and treating abdominal aortic aneurysms. The endoprosthesis features an anchoring and sealing component and low profile bifurcated legs. A biocompatible graft material is secured to at least the bifurcated legs in order to provide two endoleg fluid flow lumens or conduits. The bifurcated legs have staggered stent elements that nest to contribute to the low profile nature of the device and additional longitudinal struts between pair of the staggered stent elements to increase the longitudinal stiffness of the bifurcated legs while maintaining the patency of the lumen created thereby.
摘要翻译：用于修复和治疗腹主动脉瘤的内假体。内假体具有锚固和密封部件和低剖面分叉的腿部。将生物相容的移植物材料固定到至少分叉的腿以便提供两个内流体流体流动管腔或导管。分叉的腿具有交错的支架元件，其嵌套以有助于装置的低调性质以及一对交错的支架元件之间的另外的纵向支柱，以增加分叉腿的纵向刚度，同时保持由此产生的内腔的通畅。

4. 发明申请

US20050288771A1 Novel stent for treatment of bifurcated lesions 有权
标题翻译：用于治疗分叉病变的新型支架
公开(公告)号：US20050288771A1
公开(公告)日：2005-12-29
申请号：US10863192
申请日：2004-06-08
申请人： David Majercak , Matthew Krever , Jin Park , Robert Burgermeister , Hikmat Hojeibane , Martin Leon
发明人： David Majercak , Matthew Krever , Jin Park , Robert Burgermeister , Hikmat Hojeibane , Martin Leon
IPC分类号： A61F2/00 , A61F2/02 , A61F2/82 , A61M29/02 , A61F2/06
CPC分类号： A61F2/856 , A61F2/91 , A61F2/915 , A61F2002/821 , A61F2002/91533 , A61F2002/91558 , A61F2210/0004 , A61F2250/0067
摘要： A stent includes a lattice defining a substantially cylindrical configuration having a proximal end portion and a distal end portion, and a middle portion between the proximal end and the distal end. The lattice being moveable from a crimped state to an expanded state, and a plurality of adjacent hoops. Each hoop has a plurality of adjacent loops. Additionally, the stent further includes a plurality of bridges connecting adjacent hoops and a plurality of extensions on the lattice. Each of the hoops and bridges define a cell. The proximal end portion and the distal end portion of the lattice have at least one cell respectively and the middle portion of the lattice has at least one cell. The plurality of extensions are on the middle portion of the lattice. The plurality of extensions are cantilevered projections from the bridges and/or hoops of the lattice. The plurality of extensions are movably deformable in a direction away from the lattice, for example, at least some of the extensions are movably deformable in a direction away from the bridges and at least some of the extensions are movably deformable in a direction away from the hoops.
摘要翻译：支架包括限定具有近端部分和远端部分的基本上圆柱形构造的格子，以及近端和远端之间的中间部分。格子可以从卷曲状态移动到展开状态，并且多个相邻的环。每个箍具有多个相邻的环。此外，支架还包括连接相邻环的多个桥和在晶格上的多个延伸部。每个环和桥定义一个单元格。晶格的近端部分和远端部分分别具有至少一个电池，并且晶格的中间部分具有至少一个电池。多个延伸部位于格子的中间部分。多个延伸部是从网格的桥和/或环的悬臂突起。所述多个延伸部在远离格子的方向上可移动地变形，例如，至少一些延伸部在远离桥梁的方向上可移动地变形，并且至少一些延伸部分沿着远离网格的方向可移动地变形箍

5. 发明申请

US20110034989A1 RAPID-EXCHANGE BALLOON CATHETER SHAFT AND METHOD 有权
标题翻译：快速交换气囊导管轴和方法
公开(公告)号：US20110034989A1
公开(公告)日：2011-02-10
申请号：US12906976
申请日：2010-10-18
申请人： Laila Al-Marashi , David Grewe , Stephen Griffin , Elaine Lim , David Majercak , Roger Stevens
发明人： Laila Al-Marashi , David Grewe , Stephen Griffin , Elaine Lim , David Majercak , Roger Stevens
IPC分类号： A61F2/84
CPC分类号： A61M25/10 , A61F2/915 , A61F2/958 , A61F2002/91558 , A61F2230/0054 , A61F2250/0018 , A61M25/0054 , A61M2025/0183
摘要： A balloon catheter or stent delivery system for medical treatment of a patient has a proximal hub, a balloon, and an improved shaft design. The catheter shaft has a rapid-exchange configuration, and a tubular outer body that includes a hypotube extending from the catheter proximal end to a position at or near a proximal leg of the balloon. An inner tubular body defines a guidewire lumen extending from a distal guidewire port at the catheter distal end to a proximal port located at a position between the balloon and the hub. A distal leg of the balloon is directly or indirectly affixed to the inner body, and a proximal leg of the balloon is affixed to the distal end of the outer body. The hypotube has an aperture for accepting the inner body proximal end, and a circumferential cut pattern. The cut pattern adds flexibility, and may extend from the hypotube distal end to a position proximal of the proximal guidewire port. The cut pattern may have any desired shape, including a spiral, a helical undulating path, or an overlapping serpentine path with inflection points, for example. The hypotube has a fluid-tight covering such as a heat-shrink polymer, so the outer body supports pressure of an inflation medium. The proximal guidewire port may be positioned on or between the individual portions of the cut pattern, or at a position beyond the cut pattern.
摘要翻译：用于患者医疗的球囊导管或支架输送系统具有近端毂，球囊和改进的轴设计。导管轴具有快速交换构造，以及管状外体，其包括从导管近端延伸到球囊的近端腿处或附近的位置的海波管。内部管状体限定从导管远端处的远端导丝端口延伸到位于气囊和轮毂之间的位置的近端口的导丝管腔。球囊的远端腿直接或间接地固定到内体上，并且气球的近端腿固定到外体的远端。海波管具有用于接纳内体近端的孔和圆周切割图案。切割图案增加了柔性，并且可以从海波管远端延伸到近端导丝端口的近端。切割图案可以具有任何期望的形状，例如包括螺旋形，螺旋形起伏路径或具有拐点的重叠蛇形路径。海波管具有流体密封的覆盖物，例如热收缩聚合物，因此外壳支撑膨胀介质的压力。近端导丝端口可以定位在切割图案的各个部分之间或之间，或位于切割图案之外的位置。

6. 发明授权

US07815600B2 Rapid-exchange balloon catheter shaft and method 有权
标题翻译：快速交换球囊导管轴和方法
公开(公告)号：US07815600B2
公开(公告)日：2010-10-19
申请号：US12008509
申请日：2008-01-11
申请人： Laila Al-Marashi , David Grewe , Stephen Griffin , Elaine Lim , David Majercak , Roger Stevens
发明人： Laila Al-Marashi , David Grewe , Stephen Griffin , Elaine Lim , David Majercak , Roger Stevens
IPC分类号： A61M31/00
CPC分类号： A61M25/10 , A61F2/915 , A61F2/958 , A61F2002/91558 , A61F2230/0054 , A61F2250/0018 , A61M25/0054 , A61M2025/0183
摘要： A rapid-exchange balloon catheter or stent delivery system, for medically treating a patient, has a proximal hub, a balloon, and an improved shaft design. The catheter shaft has a tubular outer body that includes a hypotube extending from the catheter proximal end to a position at or near the proximal leg of the balloon. An inner tubular body defines a guidewire lumen and extends from a distal guidewire port at the catheter distal end to proximal guidewire port located between the balloon and the proximal hub. The hypotube has an aperture for accepting the inner body proximal end and a circumferential cut pattern. The cut pattern adds flexibility and may have any desired shape, including a spiral, a helical undulating path, or an overlapping serpentine path with inflection points, for example. The proximal guidewire port may be positioned on or in between the individual portions of the cut pattern.
摘要翻译：用于医疗治疗患者的快速交换气囊导管或支架输送系统具有近端毂，球囊和改进的轴设计。导管轴具有管状外体，其包括从导管近端延伸到球囊近端腿处或附近的位置的海波管。内管状体限定了导丝内腔，并且从导管远端处的远端导丝端口延伸到位于气囊和近端毂之间的近端导丝端口。海波管具有用于接纳内体近端和圆周切割图案的孔。切割图案增加了柔性，并且可以具有任何期望的形状，例如包括螺旋形，螺旋形波形路径或具有拐点的重叠蛇形路径。近端导丝端口可以定位在切割图案的各个部分之间或之中。

7. 发明申请

US20060025850A1 Reduced profile AAA device 有权
标题翻译：缩减配置文件AAA设备
公开(公告)号：US20060025850A1
公开(公告)日：2006-02-02
申请号：US11190367
申请日：2005-07-27
申请人： Frederick Feller , David Majercak , Jin Park
发明人： Frederick Feller , David Majercak , Jin Park
IPC分类号： A61F2/90
CPC分类号： C25F3/16 , A61F2/07 , A61F2/856 , A61F2/89 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2220/0016 , A61F2220/0066 , A61F2220/0075 , A61F2230/0054 , A61F2230/0067 , A61F2250/0037 , A61F2250/0039
摘要： An abdominal aortic aneurysm endoprosthesis having a reduced profile for percutaneous delivery of the endoprosthesis. The endoprosthesis provides a cranial section supported by a stent, and a bifurcated caudal section having at least two legs each of which are supported by individual stents. The individual stents of each leg of the caudal section are staggered so as not to line up with one another. Altering the lengths of the legs permits nesting of the endoprosthesis. Optimizing the expansion ratio and radial strength of the endoprosthesis is achieved by altering the dimensions of the starting material from which the stent segments are fabricated, by altering the final austentite temperature of the starting materials, or by changing the structural configuration of the stent segments. A graft material is attached to at least a portion of the cranial section and to all of the caudal section of the endoprosthesis.
摘要翻译：腹主动脉瘤内用假体具有减少的内皮假体经皮递送的轮廓。内假体提供由支架支撑的颅面部分和具有至少两个腿的分叉尾部，每个腿由各个支架支撑。尾部各腿的个体支架交错排列，以免彼此排列。改变腿部的长度允许内置假体嵌套。通过改变制造支架段的起始材料的尺寸，通过改变起始材料的最终奥氏体温度，或通过改变支架段的结构构造来实现内部假体的膨胀比和径向强度的优化。移植材料附着到颅部的至少一部分和内置假体的所有尾部。

8. 发明申请

US20050171592A1 Spiral centering catheter 有权
标题翻译：螺旋定心导管
公开(公告)号：US20050171592A1
公开(公告)日：2005-08-04
申请号：US10973583
申请日：2004-10-26
申请人： David Majercak
发明人： David Majercak
IPC分类号： A61F2/82 , A61F2/84 , A61M25/00 , A61F2/06 , A61N5/00
CPC分类号： A61M25/0069 , A61F2/958 , A61M25/0043 , A61M2025/1047
摘要： A catheter with proximal and distal ends having a spiral centering device attached near the catheter distal end. The spiral centering device has at least one spiral strut having a proximal end and a distal end. The spiral centering device resiliently tends to center the distal end portion of the catheter, steering the catheter away from the vessel wall during insertion through the vasculature and toward the treatment site. The spiral centering catheter may facilitate access to tortuous anatomy by preventing the distal catheter tip from catching on irregularities in the lumenal surface. If a stent is provided on the catheter, the spiral centering catheter may also facilitate uniform stent expansion by stabilizing the catheter during stent deployment.
摘要翻译：具有近端和远端的导管具有附接在导管远端附近的螺旋定心装置。螺旋定心装置具有至少一个具有近端和远端的螺旋支柱。螺旋定心装置弹性地倾向于使导管的远端部分居中，在插入通过脉管系统并朝向治疗部位时将导管转向血管壁。螺旋定心导管可以通过防止远侧导管尖端捕获内腔表面的不规则性来促进进入曲折的解剖结构。如果在导管上设置支架，则螺旋定心导管还可以通过在支架展开期间稳定导管来促进均匀的支架扩张。

9. 发明申请

US20050165474A1 Flexible stent 有权
标题翻译：柔性支架
公开(公告)号：US20050165474A1
公开(公告)日：2005-07-28
申请号：US11084834
申请日：2005-03-18
申请人： David Majercak , Hikmat Hojeibane , Robert Burgermeister
发明人： David Majercak , Hikmat Hojeibane , Robert Burgermeister
IPC分类号： A61F2/84 , A61F2/00 , A61F2/06 , A61F2/90 , A61M29/02 , C23F1/02
CPC分类号： A61F2/915 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91566 , A61F2002/91575 , A61F2002/91583 , A61F2230/0054 , A61F2250/0036 , C23F1/02
摘要： A stent provides a folded strut section that provides both structural rigidity and reduction in foreshortening of the stent mechanism. A flexible section provides flexibility for delivery of the stent mechanism. In a second embodiment, flexible section columns are angled with respect to each other, and to the longitudinal axis of the stent. These relatively flexible sections are oppositely phased in order to negate any torsion along their length. In yet another embodiment, the flexible connector can take on an undulating shape (like an “N”), but such that the longitudinal axis of the connector is not parallel with the longitudinal axis of the stent. Finally, a new method is disclosed for making stents.
摘要翻译：支架提供折叠的支柱部分，其提供了支架机构的缩短的结构刚性和减少。柔性部分为支架机构的传送提供了灵活性。在第二实施例中，柔性截面柱相对于彼此和支架的纵向轴线成一角度。这些相对柔性的部分是相反的，以便否定沿其长度的任何扭转。在另一个实施例中，柔性连接器可以呈波状形状（例如“N”），但是使得连接器的纵向轴线不与支架的纵向轴线平行。最后，公开了一种用于制作支架的新方法。

10. 发明授权

US08454673B2 Rapid-exchange balloon catheter shaft and method 有权
标题翻译：快速交换球囊导管轴和方法
公开(公告)号：US08454673B2
公开(公告)日：2013-06-04
申请号：US12906976
申请日：2010-10-18
申请人： Laila Al-Marashi , David Grewe , Stephen Griffin , Elaine Lim , David Majercak , Roger Stevens
发明人： Laila Al-Marashi , David Grewe , Stephen Griffin , Elaine Lim , David Majercak , Roger Stevens
IPC分类号： A61F2/84
CPC分类号： A61M25/10 , A61F2/915 , A61F2/958 , A61F2002/91558 , A61F2230/0054 , A61F2250/0018 , A61M25/0054 , A61M2025/0183
摘要： A balloon catheter or stent delivery system for medical treatment of a patient has a proximal hub, a balloon, and an improved shaft design. The catheter shaft has a rapid-exchange configuration, and a tubular outer body that includes a hypotube extending from the catheter proximal end to a position at or near a proximal leg of the balloon. An inner tubular body defines a guidewire lumen extending from a distal guidewire port at the catheter distal end to a proximal port located at a position between the balloon and the hub. A distal leg of the balloon is directly or indirectly affixed to the inner body, and a proximal leg of the balloon is affixed to the distal end of the outer body. The hypotube has an aperture for accepting the inner body proximal end, and a circumferential cut pattern. The cut pattern adds flexibility, and may extend from the hypotube distal end to a position proximal of the proximal guidewire port. The cut pattern may have any desired shape, including a spiral, a helical undulating path, or an overlapping serpentine path with inflection points, for example. The hypotube has a fluid-tight covering such as a heat-shrink polymer, so the outer body supports pressure of an inflation medium. The proximal guidewire port may be positioned on or between the individual portions of the cut pattern, or at a position beyond the cut pattern.
摘要翻译：用于患者医疗的球囊导管或支架输送系统具有近端毂，球囊和改进的轴设计。导管轴具有快速交换构造，以及管状外体，其包括从导管近端延伸到球囊的近端腿处或附近的位置的海波管。内部管状体限定从导管远端处的远端导丝端口延伸到位于气囊和轮毂之间的位置的近端口的导丝管腔。球囊的远端腿直接或间接地固定到内体上，并且气球的近端腿固定到外体的远端。海波管具有用于接纳内体近端的孔和圆周切割图案。切割图案增加了柔性，并且可以从海波管远端延伸到近端导丝端口的近端。切割图案可以具有任何期望的形状，例如包括螺旋形，螺旋形起伏路径或具有拐点的重叠蛇形路径。海波管具有流体密封的覆盖物，例如热收缩聚合物，因此外壳支撑膨胀介质的压力。近端导丝端口可以定位在切割图案的各个部分之间或之间，或位于切割图案之外的位置。

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