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1. 发明授权

US08454673B2 Rapid-exchange balloon catheter shaft and method 有权
标题翻译：快速交换球囊导管轴和方法
公开(公告)号：US08454673B2
公开(公告)日：2013-06-04
申请号：US12906976
申请日：2010-10-18
申请人： Laila Al-Marashi , David Grewe , Stephen Griffin , Elaine Lim , David Majercak , Roger Stevens
发明人： Laila Al-Marashi , David Grewe , Stephen Griffin , Elaine Lim , David Majercak , Roger Stevens
IPC分类号： A61F2/84
CPC分类号： A61M25/10 , A61F2/915 , A61F2/958 , A61F2002/91558 , A61F2230/0054 , A61F2250/0018 , A61M25/0054 , A61M2025/0183
摘要： A balloon catheter or stent delivery system for medical treatment of a patient has a proximal hub, a balloon, and an improved shaft design. The catheter shaft has a rapid-exchange configuration, and a tubular outer body that includes a hypotube extending from the catheter proximal end to a position at or near a proximal leg of the balloon. An inner tubular body defines a guidewire lumen extending from a distal guidewire port at the catheter distal end to a proximal port located at a position between the balloon and the hub. A distal leg of the balloon is directly or indirectly affixed to the inner body, and a proximal leg of the balloon is affixed to the distal end of the outer body. The hypotube has an aperture for accepting the inner body proximal end, and a circumferential cut pattern. The cut pattern adds flexibility, and may extend from the hypotube distal end to a position proximal of the proximal guidewire port. The cut pattern may have any desired shape, including a spiral, a helical undulating path, or an overlapping serpentine path with inflection points, for example. The hypotube has a fluid-tight covering such as a heat-shrink polymer, so the outer body supports pressure of an inflation medium. The proximal guidewire port may be positioned on or between the individual portions of the cut pattern, or at a position beyond the cut pattern.
摘要翻译：用于患者医疗的球囊导管或支架输送系统具有近端毂，球囊和改进的轴设计。导管轴具有快速交换构造，以及管状外体，其包括从导管近端延伸到球囊的近端腿处或附近的位置的海波管。内部管状体限定从导管远端处的远端导丝端口延伸到位于气囊和轮毂之间的位置的近端口的导丝管腔。球囊的远端腿直接或间接地固定到内体上，并且气球的近端腿固定到外体的远端。海波管具有用于接纳内体近端的孔和圆周切割图案。切割图案增加了柔性，并且可以从海波管远端延伸到近端导丝端口的近端。切割图案可以具有任何期望的形状，例如包括螺旋形，螺旋形起伏路径或具有拐点的重叠蛇形路径。海波管具有流体密封的覆盖物，例如热收缩聚合物，因此外壳支撑膨胀介质的压力。近端导丝端口可以定位在切割图案的各个部分之间或之间，或位于切割图案之外的位置。

2. 发明申请

US20080147001A1 Rapid-exchange balloon catheter shaft and method 有权
标题翻译：快速交换球囊导管轴和方法
公开(公告)号：US20080147001A1
公开(公告)日：2008-06-19
申请号：US12008509
申请日：2008-01-11
申请人： Laila Al-Marashi , David Grewe , Stephen Griffin , Elaine Lim , David Majercak , Roger Stevens
发明人： Laila Al-Marashi , David Grewe , Stephen Griffin , Elaine Lim , David Majercak , Roger Stevens
IPC分类号： A61M25/10 , A61F2/84
CPC分类号： A61M25/10 , A61F2/915 , A61F2/958 , A61F2002/91558 , A61F2230/0054 , A61F2250/0018 , A61M25/0054 , A61M2025/0183
摘要： A balloon catheter or stent delivery system for medical treatment of a patient has a proximal hub, a balloon, and an improved shaft design. The catheter shaft has a rapid-exchange configuration, and a tubular outer body that includes a hypotube extending from the catheter proximal end to a position at or near a proximal leg of the balloon. An inner tubular body defines a guidewire lumen extending from a distal guidewire port at the catheter distal end to a proximal port located at a position between the balloon and the hub. A distal leg of the balloon is directly or indirectly affixed to the inner body, and a proximal leg of the balloon is affixed to the distal end of the outer body. The hypotube has an aperture for accepting the inner body proximal end, and a circumferential cut pattern. The cut pattern adds flexibility, and may extend from the hypotube distal end to a position proximal of the proximal guidewire port. The cut pattern may have any desired shape, including a spiral, a helical undulating path, or an overlapping serpentine path with inflection points, for example. The hypotube has a fluid-tight covering such as a heat-shrink polymer, so the outer body supports pressure of an inflation medium. The proximal guidewire port may be positioned on or between the individual portions of the cut pattern, or at a position beyond the cut pattern.
摘要翻译：用于患者医疗的球囊导管或支架输送系统具有近端毂，球囊和改进的轴设计。导管轴具有快速交换构造，以及管状外体，其包括从导管近端延伸到球囊的近端腿处或附近的位置的海波管。内部管状体限定从导管远端处的远端导丝端口延伸到位于气囊和轮毂之间的位置的近端口的导丝管腔。球囊的远端腿直接或间接地固定到内体上，并且气球的近端腿固定到外体的远端。海波管具有用于接纳内体近端的孔和圆周切割图案。切割图案增加了柔性，并且可以从海波管远端延伸到近端导丝端口的近端。切割图案可以具有任何期望的形状，例如包括螺旋形，螺旋形起伏路径或具有拐点的重叠蛇形路径。海波管具有流体密封的覆盖物，例如热收缩聚合物，因此外壳支撑膨胀介质的压力。近端导丝端口可以定位在切割图案的各个部分之间或之间，或位于切割图案之外的位置。

3. 发明申请

US20110034989A1 RAPID-EXCHANGE BALLOON CATHETER SHAFT AND METHOD 有权
标题翻译：快速交换气囊导管轴和方法
公开(公告)号：US20110034989A1
公开(公告)日：2011-02-10
申请号：US12906976
申请日：2010-10-18
申请人： Laila Al-Marashi , David Grewe , Stephen Griffin , Elaine Lim , David Majercak , Roger Stevens
发明人： Laila Al-Marashi , David Grewe , Stephen Griffin , Elaine Lim , David Majercak , Roger Stevens
IPC分类号： A61F2/84
CPC分类号： A61M25/10 , A61F2/915 , A61F2/958 , A61F2002/91558 , A61F2230/0054 , A61F2250/0018 , A61M25/0054 , A61M2025/0183
摘要： A balloon catheter or stent delivery system for medical treatment of a patient has a proximal hub, a balloon, and an improved shaft design. The catheter shaft has a rapid-exchange configuration, and a tubular outer body that includes a hypotube extending from the catheter proximal end to a position at or near a proximal leg of the balloon. An inner tubular body defines a guidewire lumen extending from a distal guidewire port at the catheter distal end to a proximal port located at a position between the balloon and the hub. A distal leg of the balloon is directly or indirectly affixed to the inner body, and a proximal leg of the balloon is affixed to the distal end of the outer body. The hypotube has an aperture for accepting the inner body proximal end, and a circumferential cut pattern. The cut pattern adds flexibility, and may extend from the hypotube distal end to a position proximal of the proximal guidewire port. The cut pattern may have any desired shape, including a spiral, a helical undulating path, or an overlapping serpentine path with inflection points, for example. The hypotube has a fluid-tight covering such as a heat-shrink polymer, so the outer body supports pressure of an inflation medium. The proximal guidewire port may be positioned on or between the individual portions of the cut pattern, or at a position beyond the cut pattern.
摘要翻译：用于患者医疗的球囊导管或支架输送系统具有近端毂，球囊和改进的轴设计。导管轴具有快速交换构造，以及管状外体，其包括从导管近端延伸到球囊的近端腿处或附近的位置的海波管。内部管状体限定从导管远端处的远端导丝端口延伸到位于气囊和轮毂之间的位置的近端口的导丝管腔。球囊的远端腿直接或间接地固定到内体上，并且气球的近端腿固定到外体的远端。海波管具有用于接纳内体近端的孔和圆周切割图案。切割图案增加了柔性，并且可以从海波管远端延伸到近端导丝端口的近端。切割图案可以具有任何期望的形状，例如包括螺旋形，螺旋形起伏路径或具有拐点的重叠蛇形路径。海波管具有流体密封的覆盖物，例如热收缩聚合物，因此外壳支撑膨胀介质的压力。近端导丝端口可以定位在切割图案的各个部分之间或之间，或位于切割图案之外的位置。

4. 发明授权

US07815600B2 Rapid-exchange balloon catheter shaft and method 有权
标题翻译：快速交换球囊导管轴和方法
公开(公告)号：US07815600B2
公开(公告)日：2010-10-19
申请号：US12008509
申请日：2008-01-11
申请人： Laila Al-Marashi , David Grewe , Stephen Griffin , Elaine Lim , David Majercak , Roger Stevens
发明人： Laila Al-Marashi , David Grewe , Stephen Griffin , Elaine Lim , David Majercak , Roger Stevens
IPC分类号： A61M31/00
CPC分类号： A61M25/10 , A61F2/915 , A61F2/958 , A61F2002/91558 , A61F2230/0054 , A61F2250/0018 , A61M25/0054 , A61M2025/0183
摘要： A rapid-exchange balloon catheter or stent delivery system, for medically treating a patient, has a proximal hub, a balloon, and an improved shaft design. The catheter shaft has a tubular outer body that includes a hypotube extending from the catheter proximal end to a position at or near the proximal leg of the balloon. An inner tubular body defines a guidewire lumen and extends from a distal guidewire port at the catheter distal end to proximal guidewire port located between the balloon and the proximal hub. The hypotube has an aperture for accepting the inner body proximal end and a circumferential cut pattern. The cut pattern adds flexibility and may have any desired shape, including a spiral, a helical undulating path, or an overlapping serpentine path with inflection points, for example. The proximal guidewire port may be positioned on or in between the individual portions of the cut pattern.
摘要翻译：用于医疗治疗患者的快速交换气囊导管或支架输送系统具有近端毂，球囊和改进的轴设计。导管轴具有管状外体，其包括从导管近端延伸到球囊近端腿处或附近的位置的海波管。内管状体限定了导丝内腔，并且从导管远端处的远端导丝端口延伸到位于气囊和近端毂之间的近端导丝端口。海波管具有用于接纳内体近端和圆周切割图案的孔。切割图案增加了柔性，并且可以具有任何期望的形状，例如包括螺旋形，螺旋形波形路径或具有拐点的重叠蛇形路径。近端导丝端口可以定位在切割图案的各个部分之间或之中。

5. 发明申请

US20120010566A1 Catheter Including a Compliant Balloon 有权
标题翻译：导管包括合适的气球
公开(公告)号：US20120010566A1
公开(公告)日：2012-01-12
申请号：US13233692
申请日：2011-09-15
申请人： Stephen Griffin , Huey Quoc Chan , Elaine Lim , Nhan Hue To
发明人： Stephen Griffin , Huey Quoc Chan , Elaine Lim , Nhan Hue To
IPC分类号： A61M25/10
CPC分类号： A61M25/1002 , A61B17/22032 , A61M25/0054 , A61M25/0105 , A61M25/10
摘要： A catheter having an elongate shaft including a plurality of apertures disposed along at least a length of the shaft to facilitate bending. The catheter includes an inflatable balloon, wherein a subset of the plurality of apertures provides fluid communication from an inflation lumen to the inflatable balloon.
摘要翻译：一种具有细长轴的导管，包括沿轴的至少一段长度设置的多个孔，以便于弯曲。导管包括可充气气囊，其中多个孔的子集提供从充气腔向可膨胀气囊的流体连通。

6. 发明授权

US08048060B2 Medical device 有权
标题翻译：医疗装置
公开(公告)号：US08048060B2
公开(公告)日：2011-11-01
申请号：US11505119
申请日：2006-08-16
申请人： Stephen Griffin , Elaine Lim , Gregory E. Mirigian
发明人： Stephen Griffin , Elaine Lim , Gregory E. Mirigian
IPC分类号： A61M25/00
CPC分类号： A61M25/0054 , A61L29/02 , A61M25/001 , A61M25/0045 , A61M25/0051 , A61M25/0053 , A61M25/0068 , A61M25/0097 , A61M25/0108 , A61M2025/0046 , A61M2205/0216 , A61M2205/0227 , A61M2205/0266
摘要： A medical device including a shaft having an elongated inner member and an elongated tubular reinforcing member disposed over at least a portion of the inner member. In some embodiments, at least a portion of the outer surface of the inner member is spaced from the inner surface of the reinforcing member, defining a space substantially free of any other structures of the device. In some embodiments, the shaft can include a tip structure disposed on a distal portion of the inner member. In some such embodiments, the reinforcing member has a distal end, and the tip structure is disposed on the distal portion of the inner member adjacent the distal end of the reinforcing member. Additionally, in some embodiments, the reinforcing member can include a plurality of apertures defined therein, for example, to enhance the flexibility or other such characteristics of all or portions of the reinforcing member.
摘要翻译：一种医疗装置，包括具有细长内部构件的轴和设置在内部构件的至少一部分上的细长管状加强构件。在一些实施例中，内部构件的外表面的至少一部分与加强构件的内表面间隔开，限定了基本上没有设备的任何其他结构的空间。在一些实施例中，轴可以包括设置在内部构件的远侧部分上的末端结构。在一些这样的实施例中，加强构件具有远端，并且尖端结构设置在邻近加强构件的远端的内部构件的远侧部分上。此外，在一些实施例中，加强构件可以包括限定在其中的多个孔，例如以增强加强构件的全部或部分的柔性或其它这些特性。

7. 发明申请

US20100087849A1 CATHETER INCLUDING A COMPLIANT BALLOON 有权
标题翻译：导管包括合适的气球
公开(公告)号：US20100087849A1
公开(公告)日：2010-04-08
申请号：US12631909
申请日：2009-12-07
申请人： Stephen Griffin , Huey Quoc Chan , Elaine Lim , Nhan Hue To
发明人： Stephen Griffin , Huey Quoc Chan , Elaine Lim , Nhan Hue To
IPC分类号： A61M25/10 , A61M25/14
CPC分类号： A61M25/1002 , A61B17/22032 , A61M25/0054 , A61M25/0105 , A61M25/10
摘要： A catheter having an elongate shaft including a plurality of apertures disposed along at least a length of the shaft to facilitate bending. The catheter includes an inflatable balloon, wherein a subset of the plurality of apertures provides fluid communication from an inflation lumen to the inflatable balloon.
摘要翻译：一种具有细长轴的导管，包括沿轴的至少一段长度设置的多个孔，以便于弯曲。导管包括可充气气囊，其中多个孔的子集提供从充气腔向可膨胀气囊的流体连通。

8. 发明申请

US20090105643A1 OCCLUSION BALLOON CATHETER WITH EXTERNAL INFLATION LUMEN 审中-公开
标题翻译：具有外部充气灯的OCCLUSION BALLOON导管
公开(公告)号：US20090105643A1
公开(公告)日：2009-04-23
申请号：US12337115
申请日：2008-12-17
申请人： Huey Quoc Chan , Stephen Griffin , Elaine Lim
发明人： Huey Quoc Chan , Stephen Griffin , Elaine Lim
IPC分类号： A61M25/10
CPC分类号： A61M25/1025 , A61M25/104 , A61M2025/1061
摘要： Catheters such as guide catheters can be configured to provide distal occlusion, while still providing sufficient interior lumen space for device delivery. Such catheters can also provide a desired level of flexibility, yet can include sufficient column support. A catheter can include an elongate shaft with a lumen, an inflatable compliant balloon disposed over the distal region of the shaft, and an external inflation component.
摘要翻译：导管如引导导管可构造为提供远端闭塞，同时仍然为装置输送提供足够的内腔空间。这样的导管也可以提供期望的柔性水平，但可以包括足够的柱支撑。导管可以包括具有内腔的细长轴，设置在轴的远侧区域上的可充气柔顺气囊和外部充气部件。

9. 发明授权

US08021329B2 Catheter including a compliant balloon 有权
标题翻译：导管包括顺应气球
公开(公告)号：US08021329B2
公开(公告)日：2011-09-20
申请号：US12631909
申请日：2009-12-07
申请人： Stephen Griffin , Huey Quoc Chan , Elaine Lim , Nhan Hue To
发明人： Stephen Griffin , Huey Quoc Chan , Elaine Lim , Nhan Hue To
IPC分类号： A61M29/00
CPC分类号： A61M25/1002 , A61B17/22032 , A61M25/0054 , A61M25/0105 , A61M25/10
摘要： A catheter having an elongate shaft including a plurality of apertures disposed along at least a length of the shaft to facilitate bending. The catheter includes an inflatable balloon, wherein a subset of the plurality of apertures provides fluid communication from an inflation lumen to the inflatable balloon.
摘要翻译：一种具有细长轴的导管，包括沿轴的至少一段长度设置的多个孔，以便于弯曲。导管包括可充气气囊，其中多个孔的子集提供从充气腔向可膨胀气囊的流体连通。

10. 发明申请

US20060129176A1 Catheter having an ultra soft tip and methods for making the same 有权
公开(公告)号：US20060129176A1
公开(公告)日：2006-06-15
申请号：US11009667
申请日：2004-12-10
申请人： Stephen Griffin , Huey Chan , Elaine Lim , Lex Jansen , Anthony Tassoni
发明人： Stephen Griffin , Huey Chan , Elaine Lim , Lex Jansen , Anthony Tassoni
IPC分类号： A61M29/00
CPC分类号： A61M25/10 , A61M25/0069 , A61M2025/1093 , Y10T29/49826
摘要： An intravascular balloon catheter having an ultra soft tip. The catheter includes a braided reinforcement member extending substantially the length of the elongate shaft. A balloon is disposed at the distal end of the elongate shaft. An ultra soft tip is formed from a distal portion of balloon material extending distal of the distal end of the elongate shaft.

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