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1. 发明申请

US20050288771A1 Novel stent for treatment of bifurcated lesions 有权
标题翻译：用于治疗分叉病变的新型支架
公开(公告)号：US20050288771A1
公开(公告)日：2005-12-29
申请号：US10863192
申请日：2004-06-08
申请人： David Majercak , Matthew Krever , Jin Park , Robert Burgermeister , Hikmat Hojeibane , Martin Leon
发明人： David Majercak , Matthew Krever , Jin Park , Robert Burgermeister , Hikmat Hojeibane , Martin Leon
IPC分类号： A61F2/00 , A61F2/02 , A61F2/82 , A61M29/02 , A61F2/06
CPC分类号： A61F2/856 , A61F2/91 , A61F2/915 , A61F2002/821 , A61F2002/91533 , A61F2002/91558 , A61F2210/0004 , A61F2250/0067
摘要： A stent includes a lattice defining a substantially cylindrical configuration having a proximal end portion and a distal end portion, and a middle portion between the proximal end and the distal end. The lattice being moveable from a crimped state to an expanded state, and a plurality of adjacent hoops. Each hoop has a plurality of adjacent loops. Additionally, the stent further includes a plurality of bridges connecting adjacent hoops and a plurality of extensions on the lattice. Each of the hoops and bridges define a cell. The proximal end portion and the distal end portion of the lattice have at least one cell respectively and the middle portion of the lattice has at least one cell. The plurality of extensions are on the middle portion of the lattice. The plurality of extensions are cantilevered projections from the bridges and/or hoops of the lattice. The plurality of extensions are movably deformable in a direction away from the lattice, for example, at least some of the extensions are movably deformable in a direction away from the bridges and at least some of the extensions are movably deformable in a direction away from the hoops.
摘要翻译：支架包括限定具有近端部分和远端部分的基本上圆柱形构造的格子，以及近端和远端之间的中间部分。格子可以从卷曲状态移动到展开状态，并且多个相邻的环。每个箍具有多个相邻的环。此外，支架还包括连接相邻环的多个桥和在晶格上的多个延伸部。每个环和桥定义一个单元格。晶格的近端部分和远端部分分别具有至少一个电池，并且晶格的中间部分具有至少一个电池。多个延伸部位于格子的中间部分。多个延伸部是从网格的桥和/或环的悬臂突起。所述多个延伸部在远离格子的方向上可移动地变形，例如，至少一些延伸部在远离桥梁的方向上可移动地变形，并且至少一些延伸部分沿着远离网格的方向可移动地变形箍

2. 发明申请

US20050131524A1 Method for treating a bifurcated vessel 审中-公开
标题翻译：治疗分叉血管的方法
公开(公告)号：US20050131524A1
公开(公告)日：2005-06-16
申请号：US10863142
申请日：2004-06-08
申请人： David Majercak , Matthew Krever , Jin Park , Robert Burgermeister , Hikmat Hojeibane , Martin Leon
发明人： David Majercak , Matthew Krever , Jin Park , Robert Burgermeister , Hikmat Hojeibane , Martin Leon
IPC分类号： A61M29/02 , A61F2/06 , A61F2/84 , A61F2/90
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91541 , A61F2002/91558 , A61F2230/0054
摘要： A method for treating a bifurcated vessel, wherein the bifurcated vessel has a main vessel and a side branch vessel extending from the main vessel. The method includes the steps of: identifying a site in the main vessel and placing a stent at the site in the main vessel. The stent includes a lattice defining a substantially cylindrical configuration having a proximal end portion and a distal end portion, and a middle portion between the proximal end portion and the distal end portion. The lattice is movable from a crimped state to an expanded state. The lattice has a plurality of adjacent hoops. Each hoop has a plurality of adjacent loops, a plurality of bridges connecting adjacent hoops, and a plurality of extensions on at least some portions of the lattice. Each of the hoops and bridges define a cell. The proximal end portion and the distal end portion of the lattice have at least one cell respectively and the middle portion of the lattice has at least one cell. The at least one cell of the middle portion has spacing between adjacent hoops that is greater than spacing between adjacent hoops of the at least one cell of the proximal end portion and the distal end portion respectively. The at least one cell of the middle portion is dilated adjacent the side branch vessel and a surface of the side branch vessel is supported with at least one of the plurality of the extensions by deformably moving the at least one of the plurality of extensions away from the lattice and into contact with the surface of the side branch vessel.
摘要翻译：一种治疗分叉血管的方法，其中分叉血管具有主血管和从主血管延伸的侧支血管。该方法包括以下步骤：识别主容器中的位置并将支架放置在主容器中的位置处。支架包括限定具有近端部分和远端部分的基本上圆柱形构造的格子，以及近端部分和远端部分之间的中间部分。格子可以从卷曲状态移动到展开状态。格子具有多个相邻的箍。每个箍具有多个相邻的环，连接相邻环的多个桥，以及在该格的至少某些部分上的多个延伸部。每个环和桥定义一个单元格。晶格的近端部分和远端部分分别具有至少一个电池，并且晶格的中间部分具有至少一个电池。中间部分的至少一个单元在相邻的箍之间具有分别大于近端部分的至少一个单元和远端部分的相邻环之间的间隔的间隔。中间部分的至少一个单元在侧分支容器附近扩张，并且侧分支容器的表面由多个延伸部中的至少一个支撑，多个延伸部中的至少一个延伸部可变形地将多个延伸部中的至少一个远离格子并与侧支血管的表面接触。

3. 发明授权

US08551154B2 Intraluminal medical device having asymetrical members of unequal length 有权
标题翻译：具有不等长度的不对称成员的管腔内医疗器械
公开(公告)号：US08551154B2
公开(公告)日：2013-10-08
申请号：US11172527
申请日：2005-06-30
申请人： Robert Burgermeister , Randy Grishaber , Ramesh Marrey , Jin Park , Mathew Krever , David Overaker
发明人： Robert Burgermeister , Randy Grishaber , Ramesh Marrey , Jin Park , Mathew Krever , David Overaker
IPC分类号： A61F2/06
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91508 , A61F2002/91533 , A61F2002/91558 , A61F2002/91583 , A61F2250/0036
摘要： This invention relates generally to expandable intraluminal medical devices for use within a body passageway or duct, and more particularly to an optimized stent having asymmetrical strut and loop members, wherein at least one pair adjacent radial strut members have unequal axial lengths.
摘要翻译：本发明一般涉及用于体内通道或管道内的可扩张的管腔内医疗装置，更具体地涉及具有不对称支柱和环构件的优化支架，其中至少一对相邻的径向支柱构件具有不等轴向长度。

4. 发明申请

US20060025846A1 AAA low profile support structure 有权
标题翻译： AAA低调支持结构
公开(公告)号：US20060025846A1
公开(公告)日：2006-02-02
申请号：US11188498
申请日：2005-07-25
申请人： Frederick Feller , David Majercak , Jin Park , Diana Sanchez
发明人： Frederick Feller , David Majercak , Jin Park , Diana Sanchez
IPC分类号： A61F2/90
CPC分类号： A61F2/856 , A61F2/07 , A61F2/89 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2002/065 , A61F2002/075 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2220/0016 , A61F2220/0066 , A61F2220/0075 , A61F2230/0054 , A61F2230/0067 , A61F2250/0037
摘要： An endoprosthesis for repairing and treating abdominal aortic aneurysms. The endoprosthesis features an anchoring and sealing component and low profile bifurcated legs. A biocompatible graft material is secured to at least the bifurcated legs in order to provide two endoleg fluid flow lumens or conduits. The bifurcated legs have staggered stent elements that nest to contribute to the low profile nature of the device and additional longitudinal struts between pair of the staggered stent elements to increase the longitudinal stiffness of the bifurcated legs while maintaining the patency of the lumen created thereby.
摘要翻译：用于修复和治疗腹主动脉瘤的内假体。内假体具有锚固和密封部件和低剖面分叉的腿部。将生物相容的移植物材料固定到至少分叉的腿以便提供两个内流体流体流动管腔或导管。分叉的腿具有交错的支架元件，其嵌套以有助于装置的低调性质以及一对交错的支架元件之间的另外的纵向支柱，以增加分叉腿的纵向刚度，同时保持由此产生的内腔的通畅。

5. 发明申请

US20070156227A1 Migration resistant prosthetic stent graft for treatment of abdominal aortic aneurysm 有权
标题翻译：用于治疗腹主动脉瘤的抗迁移性假体支架移植物
公开(公告)号：US20070156227A1
公开(公告)日：2007-07-05
申请号：US11323781
申请日：2005-12-30
申请人： Isaac Khan , David Majercak , Jin Park , Diana Sanchez
发明人： Isaac Khan , David Majercak , Jin Park , Diana Sanchez
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2/90 , A61F2002/075 , A61F2230/0078 , A61F2250/0069
摘要： A prosthetic stent graft for the treatment of AAA includes a plurality of graft legs, each secured in a deployed position by a sealing gasket within a stent segment of the sealing gasket and to one side of a framing bracket. The framing bracket traverses the diameter of the stent segment and extends axially away, dividing the first stent segment into two portions, each portion for receiving a graft leg of the stent graft. The sealing gasket can include a stabilizer having a second generally cylindrical stent segment, and an extension bracket traversing the diameter of the second stent segment and extending away from the second stent segment. The extension bracket and the first bracket are connected with one another at a mutual generally central position.
摘要翻译：用于治疗AAA的假体支架移植物包括多个移植腿，每个移植腿通过密封垫片的支架段内的密封垫圈和框架支架的一侧固定在展开位置。框架托架穿过支架段的直径并轴向延伸，将第一支架段分成两部分，每个部分用于接收支架移植物的移植腿。密封垫片可以包括具有第二大致圆柱形的支架段的稳定器和横穿第二支架段的直径并延伸离开第二支架段的延伸支架。延伸支架和第一支架在相互大体上的中心位置处彼此连接。

6. 发明申请

US20060025844A1 Reduced deployment force delivery device 有权
标题翻译：减少部署力输送装置
公开(公告)号：US20060025844A1
公开(公告)日：2006-02-02
申请号：US11190369
申请日：2005-07-27
申请人： David Majercak , Jin Park , Diana Sanchez
发明人： David Majercak , Jin Park , Diana Sanchez
IPC分类号： A61F2/06
CPC分类号： A61F2/966 , A61F2/95 , A61F2002/9665
摘要： A reduced deployment force delivery apparatus having an outer sheath with two layers that move relative to one another so as to reduce the deployment force necessary for deploying a stent, stent graft or other intraluminal device.
摘要翻译：一种减小的展开力输送装置，具有一个具有两层相互相对移动的外护套，以便减少展开支架，支架移植物或其他管腔内装置所需的展开力。

7. 发明申请

US20070151638A1 Method to develop an organized microstructure within an implantable medical device 审中-公开
标题翻译：在可植入医疗装置内开发有组织的微结构的方法
公开(公告)号：US20070151638A1
公开(公告)日：2007-07-05
申请号：US11321547
申请日：2005-12-29
申请人： Robert Burgermeister , Randy-David Grishaber , Jin Park
发明人： Robert Burgermeister , Randy-David Grishaber , Jin Park
IPC分类号： C21D6/00 , C22F1/00
CPC分类号： A61L27/50 , A61L2400/18
摘要： A method to facilitate the ability to engineer an organized microstructure within a monolithically homogeneous implantable biomaterial, particularly metallic alloys, is provided. By starting with an ultra-fine grained, equiaxed microstructure having an averaged linear grain size of less than 5 microns, a functionally graded microstructure is developed by establishing a temperature gradient across the cross sectional dimension. In the case of a tubular product form, this dimension would be framed by the outer and inner surfaces. By ensuring one surface is held at a substantially lower temperature than the other surface a temperature gradient is developed. The present invention also provides an implantable medical device which includes an organized microstructure. In accordance with the present invention, the organized microstructure includes a first surface region having said ultra-fine grained, equiaxed microstructure and a second surface region comprising a recrystallized, coarser grained microstructure having an average linear grain size of greater than 25 microns, wherein the first and second surface regions are separated by a transition region.
摘要翻译：提供了一种有助于在单一均匀的可植入生物材料，特别是金属合金中设计有组织的微结构的能力的方法。通过从具有小于5微米的平均线性晶粒尺寸的超细晶粒等轴显微组织开始，通过在横截面尺寸上建立温度梯度来开发功能梯度的微结构。在管状产品形式的情况下，该尺寸将由外表面和内表面构成。通过确保一个表面保持在比另一个表面基本上更低的温度，开发温度梯度。本发明还提供了一种包括有组织的微结构的可植入医疗装置。根据本发明，有组织的微结构包括具有所述超细晶粒等轴显微组织的第一表面区域和包含平均线性晶粒尺寸大于25微米的再结晶，粗晶粒微结构的第二表面区域，其中，第一和第二表面区域被过渡区域分开。

8. 发明申请

US20060009836A1 Intraluminal medical device having asymetrical members 审中-公开
标题翻译：具有不对称成员的管腔内医疗器械
公开(公告)号：US20060009836A1
公开(公告)日：2006-01-12
申请号：US11172103
申请日：2005-06-30
申请人： Robert Burgermeister , Thomas Duerig , Randy Grishaber , Ramesh Marrey , Jin Park , Mathew Krever
发明人： Robert Burgermeister , Thomas Duerig , Randy Grishaber , Ramesh Marrey , Jin Park , Mathew Krever
IPC分类号： A61F2/06
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2002/91558 , A61F2230/0013 , A61F2250/0029 , A61F2250/0036
摘要： This invention relates generally to expandable intraluminal medical devices for use within a body passageway or duct, and more particularly to an optimized stent having asymmetrical strut and loop members. In one embodiment of the invention the stent includes one or more members each having at least one component. The component has non-uniform cross-sections to achieve near-uniform stress distribution along the component when the component undergoes deformation.
摘要翻译：本发明一般涉及用于体内通道或管道内的可扩张的腔内医疗装置，更具体地涉及具有不对称支柱和环构件的优化的支架。在本发明的一个实施例中，支架包括一个或多个各自具有至少一个部件的部件。该部件具有不均匀的横截面，以在部件经历变形时沿着部件实现近均匀的应力分布。

9. 发明申请

US20060025850A1 Reduced profile AAA device 有权
标题翻译：缩减配置文件AAA设备
公开(公告)号：US20060025850A1
公开(公告)日：2006-02-02
申请号：US11190367
申请日：2005-07-27
申请人： Frederick Feller , David Majercak , Jin Park
发明人： Frederick Feller , David Majercak , Jin Park
IPC分类号： A61F2/90
CPC分类号： C25F3/16 , A61F2/07 , A61F2/856 , A61F2/89 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2220/0016 , A61F2220/0066 , A61F2220/0075 , A61F2230/0054 , A61F2230/0067 , A61F2250/0037 , A61F2250/0039
摘要： An abdominal aortic aneurysm endoprosthesis having a reduced profile for percutaneous delivery of the endoprosthesis. The endoprosthesis provides a cranial section supported by a stent, and a bifurcated caudal section having at least two legs each of which are supported by individual stents. The individual stents of each leg of the caudal section are staggered so as not to line up with one another. Altering the lengths of the legs permits nesting of the endoprosthesis. Optimizing the expansion ratio and radial strength of the endoprosthesis is achieved by altering the dimensions of the starting material from which the stent segments are fabricated, by altering the final austentite temperature of the starting materials, or by changing the structural configuration of the stent segments. A graft material is attached to at least a portion of the cranial section and to all of the caudal section of the endoprosthesis.
摘要翻译：腹主动脉瘤内用假体具有减少的内皮假体经皮递送的轮廓。内假体提供由支架支撑的颅面部分和具有至少两个腿的分叉尾部，每个腿由各个支架支撑。尾部各腿的个体支架交错排列，以免彼此排列。改变腿部的长度允许内置假体嵌套。通过改变制造支架段的起始材料的尺寸，通过改变起始材料的最终奥氏体温度，或通过改变支架段的结构构造来实现内部假体的膨胀比和径向强度的优化。移植材料附着到颅部的至少一部分和内置假体的所有尾部。

10. 发明申请

US20060030930A1 Intraluminal medical device having asymetrical members of unequal length 有权
公开(公告)号：US20060030930A1
公开(公告)日：2006-02-09
申请号：US11172527
申请日：2005-06-30
申请人： Robert Burgermeister , Randy Grishaber , Ramesh Marrey , Jin Park , Mathew Krever , David Overaker
发明人： Robert Burgermeister , Randy Grishaber , Ramesh Marrey , Jin Park , Mathew Krever , David Overaker
IPC分类号： A61F2/06
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91508 , A61F2002/91533 , A61F2002/91558 , A61F2002/91583 , A61F2250/0036
摘要： This invention relates generally to expandable intraluminal medical devices for use within a body passageway or duct, and more particularly to an optimized stent having asymmetrical strut and loop members, wherein at least one pair adjacent radial strut members have unequal axial lengths.

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