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    • 13. 发明授权
    • Apparatus and methods for determining optical tissue properties
    • US10775308B2
    • 2020-09-15
    • US11844551
    • 2007-08-24
    • Daniel G. StearnsBradley W. Rice
    • Daniel G. StearnsBradley W. Rice
    • G01N21/64A61B5/00G01N21/47
    • Disclosed are apparatus and methods for determining accurate optical property values of turbid media. In one embodiment, the method includes (a) providing a light source, having a first wavelength and a known illumination power, sequentially at a plurality of specific illumination positions on a first surface of the specimen; (b) for each specific position of the light source, obtaining light emission measurements from a second surface of the specimen that is opposite the first surface, wherein the light emission measurements are obtained for a plurality of surface positions of the second surface; and (c) for each specific illumination position of the light source at the first surface of the specimen, determining one or more optical properties for the specimen based on the specific illumination position of the light source, the first wavelength of the light source, the known illumination power of the light source, and the obtained light emission measurements for such each specific illumination position. The optical properties for the plurality of specific illumination positions of the light source are individually determined for each specific illumination position of the light source.
    • 14. 发明授权
    • Imaging system
    • 成像系统
    • US08825140B2
    • 2014-09-02
    • US13397518
    • 2012-02-15
    • Bradley W. RiceDaniel G. StearnsTamara L. Troy
    • Bradley W. RiceDaniel G. StearnsTamara L. Troy
    • A61B6/00
    • G01N21/6456G01N21/4795G01N21/6428
    • A method of investigating the location and size of a light-emitting source in a subject is disclosed. In practicing the method, one first obtains a light intensity profile by measuring, from a first perspective with a photodetector device, photons which (i) originate from the light-emitting source, (ii) travel through turbid biological tissue of the subject, and (iii) are emitted from a first surface region of interest of the subject. The light-intensity profile is matched against with a parameter-based biophotonic function, to estimate function parameters such as depth and size. The parameters so determined are refined using data other than the first measured light intensity profile, to obtain an approximate depth and size of the source in the subject. Also disclosed is an apparatus for carrying out the method.
    • 公开了一种调查受试者中发光源的位置和尺寸的方法。 在实施该方法时,首先通过用光电检测器件从第一个角度测量光源(i)来源于发光源,(ii)穿过受试者的混浊生物组织,以及 (iii)从对象的感兴趣的第一表面区域发射。 光强度曲线与基于参数的生物光子函数匹配,以估计诸如深度和大小的函数参数。 使用除第一测量光强度分布之外的数据来精确地确定如此确定的参数,以获得对象中源的近似深度和大小。 还公开了一种用于执行该方法的装置。
    • 17. 发明授权
    • Method and apparatus for determining target depth, brightness and size within a body region
    • 用于确定身体区域内的目标深度,亮度和尺寸的方法和装置
    • US07403812B2
    • 2008-07-22
    • US10151463
    • 2002-05-17
    • Bradley W. RiceDaniel G. StearnsTamara L. Troy
    • Bradley W. RiceDaniel G. StearnsTamara L. Troy
    • A61B6/00
    • G01N21/6456G01N21/4795G01N21/6428
    • A method of investigating the location and size of a light-emitting source in a subject is disclosed. In practicing the method, one first obtains a light intensity profile by measuring, from a first perspective with a photodetector device, photons which (i) originate from the light-emitting source, (ii) travel through turbid biological tissue of the subject, and (iii) are emitted from a first surface region of interest of the subject. The light-intensity profile is matched against with a parameter-based biophotonic function, to estimate function parameters such as depth and size. The parameters so determined are refined using data other than the first measured light intensity profile, to obtain an approximate depth and size of the source in the subject. Also disclosed is an apparatus for carrying out the method.
    • 公开了一种调查受试者中发光源的位置和尺寸的方法。 在实施该方法时,首先通过用光电检测器件从第一个角度测量光源(i)来源于发光源,(ii)穿过受试者的混浊生物组织,以及 (iii)从对象的感兴趣的第一表面区域发射。 光强度曲线与基于参数的生物光子函数匹配,以估计诸如深度和大小的函数参数。 使用除第一测量光强度分布之外的数据来精确地确定如此确定的参数,以获得对象中源的近似深度和大小。 还公开了一种用于执行该方法的装置。
    • 20. 发明授权
    • Repair of localized defects in multilayer-coated reticle blanks for extreme ultraviolet lithography
    • 修复用于极紫外光刻的多层涂层掩模版坯料中的局部缺陷
    • US06821682B1
    • 2004-11-23
    • US09669390
    • 2000-09-26
    • Daniel G. StearnsDonald W. SweeneyPaul B. Mirkarimi
    • Daniel G. StearnsDonald W. SweeneyPaul B. Mirkarimi
    • G03F900
    • G02B5/285B82Y10/00B82Y40/00G02B5/0891G02B27/32G03F1/24G03F1/72G21K1/062G21K2201/067
    • A method is provided for repairing defects in a multilayer coating layered onto a reticle blank used in an extreme ultraviolet lithography (EUVL) system. Using high lateral spatial resolution, energy is deposited in the multilayer coating in the vicinity of the defect. This can be accomplished using a focused electron beam, focused ion beam or a focused electromagnetic radiation. The absorbed energy will cause a structural modification of the film, producing a localized change in the film thickness. The change in film thickness can be controlled with sub-nanometer accuracy by adjusting the energy dose. The lateral spatial resolution of the thickness modification is controlled by the localization of the energy deposition. The film thickness is adjusted locally to correct the perturbation of the reflected field. For example, when the structural modification is a localized film contraction, the repair of a defect consists of flattening a mound or spreading out the sides of a depression.
    • 提供了一种用于修复分层到用于极紫外光刻(EUVL)系统的掩模版坯料上的多层涂层中的缺陷的方法。 使用高横向空间分辨率,能量沉积在缺陷附近的多层涂层中。 这可以使用聚焦电子束,聚焦离子束或聚焦电磁辐射来实现。 吸收的能量将导致膜的结构改性,产生膜厚度的局部变化。 通过调节能量剂量可以以亚纳米精度控制膜厚的变化。 厚度变化的横向空间分辨率由能量沉积的定位来控制。 局部调整膜厚以校正反射场的扰动。 例如,当结构改性是局部薄膜收缩时,缺陷的修复包括使平坦化的墩或扩展凹陷的侧面。