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1. 发明申请

WO2021127512A1 SYSTEM AND METHOD FOR SPECTRAL LIBRARY TRAINING 审中-公开
公开(公告)号：WO2021127512A1
公开(公告)日：2021-06-24
申请号：PCT/US2020/066132
申请日：2020-12-18
申请人： CHEMIMAGE CORPORATION
发明人： ZRIMSEK, Alyssa , GOMER, Heather , TAZIK, Shawna
IPC分类号： A61B1/04 , A61B1/06 , G01J3/0218 , G01J3/0224 , G01J3/0227 , G01J3/0245 , G01J3/447 , G01J3/457
摘要： Techniques, devices and methods for discriminating a target from a background material without optimizing directly on the target are provided. The devices and methods can generate pass bands of single or multiple wavelengths of variable shape and intensity, and can also select and control the shape of the pass band profiles to improve the detection of targets of interest.

2. 发明申请

WO2015172056A1 SYSTEMS AND METHODS FOR DETECTING GAS LEAKS 审中-公开
标题翻译：用于检测气体泄漏的系统和方法
公开(公告)号：WO2015172056A1
公开(公告)日：2015-11-12
申请号：PCT/US2015/029943
申请日：2015-05-08
申请人： KAIROS AEROSPACE INC.
发明人： JONES, Brian, Butler , DEIKER, Steven, William
IPC分类号： G01J3/457 , G01N21/19 , G01N21/3504
CPC分类号： G01N21/3504 , G01M3/205 , G01M3/38 , G01N21/3103 , G01N21/90 , G01N2021/1795 , G01N2021/3531
摘要： The invention is directed to improved systems, methods, and computer readable media for detecting gas leaks. More particularly, the invention detects gas leaks or discharges, such as methane or any other suitable gases, by analyzing reflected or direct light that passes through a region of enhanced target gas concentration. The invention collects light and processes spectral data of the light. All molecules are subject to rotational motions, vibrational motions, and/or combinations thereof (rovibrational motions), in which the atoms in the molecule are vibrating with respect to each other and/or rotating around each other. When the light passes through the region of the target gas, a portion of the light with certain wavelengths will be absorbed by the target gas due to the rovibrational motions of the target gas molecules. By analyzing the magnitude of absorption at certain wavelengths, one can determine the concentration of certain target gas or gases.
摘要翻译：本发明涉及用于检测气体泄漏的改进的系统，方法和计算机可读介质。更具体地，本发明通过分析通过增强的目标气体浓度的区域的反射或直射光来检测气体泄漏或排出物，例如甲烷或任何其它合适的气体。本发明收集光并处理光的光谱数据。所有分子经受旋转运动，振动运动和/或其组合（振动运动），其中分子中的原子相对于彼此振动和/或彼此旋转。当光通过目标气体的区域时，由于目标气体分子的振动运动，具有一定波长的光的一部分将被目标气体吸收。通过分析某些波长的吸收幅度，可以确定某些目标气体或气体的浓度。

3. 发明申请

WO2004013610A3 METHOD OF MEASURING MOLECULAR INTERACTIONS 审中-公开
标题翻译：测量分子相互作用的方法
公开(公告)号：WO2004013610A3
公开(公告)日：2004-05-21
申请号：PCT/US0324780
申请日：2003-08-01
申请人： SENSOR TECHNOLOGIES LLC
发明人： WOLF DAVID E , BULSECO DYLAN A
IPC分类号： C12M1/00 , C12M1/34 , C12N15/09 , C12Q1/02 , C12Q1/04 , C12Q1/68 , C12Q1/70 , G01J3/44 , G01J3/457 , G01N21/64 , G01N21/78 , G01N33/58 , G12Q1/68 , C07H21/04 , C12M1/36 , C12P19/34
CPC分类号： G01N21/6428 , G01J3/4406 , G01J3/457 , G01N21/645 , G01N33/582 , G01N2021/6417 , G01N2021/6482 , G01N2021/6484
摘要： The invention features a method of assaying for the interaction of a probe and an unknown target, said method including a) exciting a sample with radiation, the sample including at least one unknown target, at least one probe, and at least one fluorescent tag, b) measuring the fluorescence from a subvolume of the sample, and c) analyzing the fluctuations of the fluorescence.
摘要翻译：本发明的特征在于测定探针与未知靶标的相互作用的方法，所述方法包括a）用辐射激发样品，所述样品包括至少一个未知靶标，至少一个探针和至少一个荧光标签， b）测量来自样品的亚体积的荧光，以及c）分析荧光的波动。

4. 发明申请

WO00062024A1 RADIATION FILTER, SPECTROMETER AND IMAGER USING A MICRO-MIRROR ARRAY 审中-公开
标题翻译：使用微镜阵列的辐射滤光片，光谱仪和成像器
公开(公告)号：WO00062024A1
公开(公告)日：2000-10-19
申请号：PCT/US2000/003764
申请日：2000-02-14
IPC分类号： G01J3/02 , G01J3/06 , G01J3/10 , G01J3/18 , G01J3/28 , G01J3/32 , G01J3/457 , G01N21/39 , G02B26/08 , G02B27/10
CPC分类号： G01J3/02 , G01J3/0218 , G01J3/0229 , G01J3/027 , G01J3/06 , G01J3/10 , G01J3/18 , G01J3/2823 , G01J3/2889 , G01J3/32 , G01J3/457 , G01J2003/2866 , G01N21/39 , G01N2021/393 , G01N2021/6463 , G02B26/0841 , G02B27/1086
摘要： A spectrometer (10) includes a two-dimensional array of modulatable microm-irrors (18), a detector (20), and an analyzer (22). The micro-mirrors are positioned for receiving individual radiation components forming a part of a radiation source. The micro-mirrors are modulated at different modulation rates in order to reflect individual radiation components at known and different modulation rates. The micro-mirrors combine a number of the reflected individual radiation components and reflect them to the detector. The detector receives the combined radiation components and creates an output signal. The analyzer is coupled to the detector to receive the output signal and to analyze at least some of the individual radiation components making up the combined reflection. By using a micro-mirror array that modulates the radiation components at different rates, all of the radiations components can be focused onto a single detector to maximize the signal-to-noise ratio of the detector.
摘要翻译：光谱仪（10）包括可调制的微反应器（18），检测器（20）和分析器（22）的二维阵列。微镜被定位成用于接收形成辐射源的一部分的各个辐射分量。以不同的调制速率调制微镜，以便以已知和不同的调制速率反射各个辐射分量。微反射镜组合了多个反射的单个辐射分量并将其反射到检测器。检测器接收组合的辐射分量并产生输出信号。分析器耦合到检测器以接收输出信号并分析构成组合反射的各个辐射分量中的至少一些。通过使用以不同速率调制辐射分量的微镜阵列，所有辐射分量可以聚焦到单个检测器上，以使检测器的信噪比最大化。

5. 发明申请

WO99023474A1 OPTICAL ARRAY SYSTEM AND READER FOR MICRO TITER PLATES 审中-公开
标题翻译：光学阵列系统和阅读器微孔板
公开(公告)号：WO99023474A1
公开(公告)日：1999-05-14
申请号：PCT/EP1998/006468
申请日：1998-10-12
IPC分类号： G01J3/457 , B01L3/00 , G01N21/03 , G01N21/25 , G01N21/27 , G01N21/64 , G01N37/00 , G02B21/00 , G02B21/16 , G02B21/36
CPC分类号： G01N21/6452 , B01L3/5085 , B01L2300/0829 , G01N21/253 , G01N21/6456 , G01N2201/024
摘要： An optical system made up of lens arrays (2i, 7) and normal lenses (41, 5, 42) is particularly suitable for use as a massive parallel reader (approx. 10 channels) for micro titer plates (1) and the like in absorption, fluorescence and luminescence.
摘要翻译：包括透镜阵列的光学系统（2 1，7）和正常透镜（41，5,42）是特别适合作为大规模并行（大约10 <2>信道）读取器用于微量滴定板（1）和在吸收，荧光和发光等。

6. 发明申请

WO99009393A1 FLUORESCENCE CORRELATION SPECTROSCOPY PROCESS AND DEVICE, IN PARTICULAR FOR POLYCHROMATIC FLUORESCENCE CORRELATION SPECTROSCOPY 审中-公开
标题翻译：方法和设备荧光相关光谱，尤其是对于更多的颜色荧光相关光谱
公开(公告)号：WO99009393A1
公开(公告)日：1999-02-25
申请号：PCT/DE1998/002307
申请日：1998-08-11
IPC分类号： G01N21/64 , G01J3/28 , G01J3/44 , G01J3/457 , G01N21/03
CPC分类号： G01J3/457 , G01J3/4406 , G01J2003/2866
摘要： According to the disclosed process, light rays enter the transparent medium in a parallel direction and are deflected inside the transparent medium towards a focus, thus avoiding the use of refractive optics. The disclosed focusing optics enable light rays of different wavelengths to be bundled onto a point within the sample, considerably simplifying the design and adjustment of a polychromatic florescence correlation spectroscopy device.
摘要翻译：在该方法中，光束入射在平行进入透明介质和所述透明介质内被偏转到一个焦点回来。这允许避免使用折射光学系统的。根据本发明的聚焦光学系统允许不同波长的光束的捆扎在样品内的点。这简化了结构和多色荧光相关光谱设备的调整是大大简化。

7. 发明申请

WO2022234289A1 HYPERSPECTRAL IMAGING METHOD 审中-公开
公开(公告)号：WO2022234289A1
公开(公告)日：2022-11-10
申请号：PCT/GB2022/051153
申请日：2022-05-06
申请人： HERIOT-WATT UNIVERSITY
发明人： REID, Derryck Telford , CHARSLEY, Jake Mark , ALTMANN, Yoann , RUTKAUSKAS, Marius
IPC分类号： G01J3/02 , G01J3/28 , G01J3/32 , G01J3/433 , G01J3/45 , G01J3/457 , G01J3/453 , H04N5/335
摘要： The present invention relates to a hyperspectral imaging method for imaging a sample, the method comprising; providing a sample; providing a broadband light source; modulating the broadband light source to provide a plurality of modulated spectra; illuminating the sample with the plurality of modulated spectra; collecting spectral image data using of a combination of bandpass sampling and non-uniform sampling; and reconstructing spectral image data whereby a sample is imaged. The invention further relates to an apparatus configured to carry out a hyperspectral imaging method.

8. 发明申请

WO2019240801A8 HIGH SENSITIVITY OPTICAL DETECTION SYSTEM 审中-公开
公开(公告)号：WO2019240801A8
公开(公告)日：2019-12-19
申请号：PCT/US2018/037590
申请日：2018-06-14
申请人： CHEN, Jinghong
发明人： CHEN, Jinghong
IPC分类号： G01J3/457 , G01J3/28 , G02B6/10 , G02B6/52
摘要： A high sensitivity optical system for detection of chemical and biological analytes is disclosed comprising a vessel, a light-guide, analytes, excitation light source(s), a detector, excitation and emission filter(s), and light directing components. The novel optical system is secured in housing and connected to devices extrinsically or intrinsically for data input, process, display, storage, and communication. This optical system could enable clinical level diagnosis of a wide range of diseases in an inexpensive mobile point-of-care format. It can be a stand alone unit with single or an array of optical structures, or used in combination with other detection systems such as mobile microscope to form a qualitative and quantitative detection apparatus. It can also be implemented in some commercial instruments to improve sensitivities. Furthermore, the form factor of the optical system can be significantly reduced to form a highly integrated lab-on-a-chip solution.

9. 发明申请

WO2019240801A1 HIGH SENSITIVITY OPTICAL DETECTION SYSTEM 审中-公开
公开(公告)号：WO2019240801A1
公开(公告)日：2019-12-19
申请号：PCT/US2018/037590
申请日：2018-06-14
申请人： JINGHONG, Chen
发明人： JINGHONG, Chen
IPC分类号： G01J3/457 , G01J3/28 , G02B6/10 , G02B6/52
摘要： A high sensitivity optical system for detection of chemical and biological analytes is disclosed comprising a vessel, a light-guide, analytes, excitation light source(s), a detector, excitation and emission filter(s), and light directing components. The novel optical system is secured in housing and connected to devices extrinsically or intrinsically for data input, process, display, storage, and communication. This optical system could enable clinical level diagnosis of a wide range of diseases in an inexpensive mobile point-of-care format. It can be a stand alone unit with single or an array of optical structures, or used in combination with other detection systems such as mobile microscope to form a qualitative and quantitative detection apparatus. It can also be implemented in some commercial instruments to improve sensitivities. Furthermore, the form factor of the optical system can be significantly reduced to form a highly integrated lab-on-a-chip solution.

10. 发明申请

WO2013147383A1 편파 매칭된 ＩｎＧａＮ/ＣｄＺｎＯ 양자 우물 구조의 광학적 성질에 대한 이론적 분석 방법 审中-公开
标题翻译：用于理想分析极化匹配的INGAN / CDZNO量子阱结构的光学性质的方法
公开(公告)号：WO2013147383A1
公开(公告)日：2013-10-03
申请号：PCT/KR2012/009474
申请日：2012-11-09
申请人： 대구가톨릭대학교 산학협력단
发明人： 박승환
IPC分类号： G01J3/457 , G06F19/00
CPC分类号： H01L33/26 , H01L33/06
摘要： 본 발명은 편파 매칭된 InGaN/CdZnO 양자 우물 구조의 광학적 성질에 대한 이론적 분석방법에 관한 것으로, 하밀토니안(Hamiltonian)을 이용해 파동함수를 구하는 파동함수 획득단계(S1단계)와; 구해진 파동함수를 이용해 포아송 방정식(Poiss on Equati on)과 함께 논리적인 자기완전성(self-consistent)의 한 방법으로 가전자띠를 구하는 가전자띠 획득단계(S2단계)와; 구해진 가전자띠를 이용하여 다체 광학적 스펙트럼을 구하는 다체 광학적 스펙트럼 취득단계(S3단계) 및; 구해진 다체 광학적 스펙트럼의 결과를 기존의 발광소자의 특성과 비교하는 특성 비교단계(S4단계)로 이루어져 양자 우물 구조의 광학적 성질에 대한 이론적 분석방법을 제공함으로써 우물과 장벽 사이의 압전분극과 자발분극의 무효화로 인해 내부 전계의 극성을 제거하여 광학적 매트릭스 요소가 크게 향상될 수 있는 각별한 장점이 있는 유용한 발명이다.
摘要翻译：本发明涉及一种用于理论分析偏振匹配InGaN / CdZnO量子阱结构的光学特性的方法，其中该方法包括：使用哈密尔顿算子获得波函数的波函数获取步骤（步骤S1）通过使用所获得的波函数的泊松方程之一通过逻辑自相一致方法之一获得价带的价带获取步骤（步骤S2）; 使用获得的价带获得多体光谱的多体光谱获取步骤（步骤S3）; 以及将多体光谱结果与典型的发光装置的特性进行比较的属性比较步骤（步骤S4）。因此，本发明的特别有利之处在于，由于压电极化无效和阱与屏障之间的自发极化，可以通过去除内部电场的极性来显着增强光矩阵元件。

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