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1. 发明申请

WO2011069002A1 ORGANOSELENIUM COMPOUNDS AND USES THEREOF 审中-公开
标题翻译：有机化合物及其用途
公开(公告)号：WO2011069002A1
公开(公告)日：2011-06-09
申请号：PCT/US2010/058779
申请日：2010-12-02
申请人： ALQUEST THERAPEUTICS, INC. , ERLANSON, Daniel, A. , HANSEN, Stig, K.
发明人： ERLANSON, Daniel, A. , HANSEN, Stig, K.
IPC分类号： C07C391/00 , C07C391/02 , A61K31/165
CPC分类号： C07C391/02 , C07D345/00
摘要： Provided herein are organoselenium compounds and pharmaceutical compositions thereof. Also provided herein are methods of treatment, prevention, or amelioration of a variety of medical disorders using the compounds and pharmaceutical compositions provided herein. reactive oxygen and nitrogen species
摘要翻译：本文提供的是有机硒化合物及其药物组合物。本文还提供使用本文提供的化合物和药物组合物治疗，预防或改善各种医学病症的方法。活性氧和氮

2. 发明申请

WO2007005609A3 SYNTHESIS OF LABELED COMPOUNDS 审中-公开
标题翻译：标记化合物的合成
公开(公告)号：WO2007005609A3
公开(公告)日：2007-05-24
申请号：PCT/US2006025585
申请日：2006-06-28
申请人： LOS ALAMOS NAT SECURITY LLC
发明人： MARTINEZ RODOLFO A , SCHMIDT JURGEN G , ALVAREZ MARC A , SILKS LOUIS A III
IPC分类号： C07F7/22 , C07C391/02 , C07F7/00
CPC分类号： C07F7/2212 , C07B2200/05 , C07C321/28 , C07C391/02 , C07F7/0818
摘要： The present invention is directed to labeled compounds of the formula Ar-Zi-Q- Z2 where Ar is an aryl group is selected from the group consisting of 1-naphthyl, substituted 1-naphthyl, 2-naphthyl, substituted 2-naphthyl, and phenyl groups with the structure (I) wherein R 1 , R 2 , R 3 , R 4 and R 5 are each independently selected from the group consisting of hydrogen, a C 1 -C 4 lower alkyl, a halogen, a phenyl, an alkoxy group and an amino group from the group consisting of NH 2 , NHR and NRR' where R and R' are each a C 1 -C 4 lower alkyl, Q is selected from the group consisting of 13 CH 2 , 13 CDH and 13 CD 2 , and Z 1 is selected from the group consisting of -S-, -S(=O)-, -S(=O) 2 -, -Se-, -Se(=O)-, and -Se(=O) 2 -, Z 2 is selected from the group consisting of -Si(R 6 R 7 R 8 ), -O(R 9 ), -Se-Ar, -Se(=O) 2 -Ar, -Se(=O) 2 -Ar, -S-Ar, -S(=O)-Ar, and -S(=O) 2 -Ar wherein R 6 , R 7 and R 8 are each independently selected from the group consisting of a C 1 -C 4 lower alkyl, R 9 is a C 1 -C 4 lower alkyl or an R 10 -Ar group where R 10 is a C 1 -C 4 alkylene group.
摘要翻译：本发明涉及式Ar-Zi-Q-Z2的标记化合物，其中Ar为芳基，选自1-萘基，取代的1-萘基，2-萘基，取代的2-萘基和具有结构（I）的苯基，其中R 1，R 2，R 3，R 4，R 4，每个独立地选自氢，C 1 -C 4低级烷基，卤素，苯基，烷氧基基团和选自NH 2，NHR和NRR'的氨基，其中R和R'各自是C≡C≡C_{4 低级烷基，Q选自由以下基团组成的组：13 CH 2，13，CDH和13 CD，其中Z 1选自-S - ， - S（= O） - ， - S（= O）2 ， - Se - ， - Se（= O） - 和-Se（= O）2 - ，Z 2选自-Si （R _{6 - [R _{7 - [R _{8 ）， -O（R 9），-Se-Ar，-Se（= O）2 -Ar，-Se（= O）2 -Ar，-S-Ar，-S（= O）-Ar和-S（= O）2 -Ar，其中R 6，R 7， R 8和R 8各自独立地选自C 1 -C 4低级烷基，R 3， 9是C 1 -C 4低级烷基或R 10 -Ar-基团，其中R 10选自低级烷基，其中R 1是C 1 -C 4亚烷基。}}}}

3. 发明申请

WO2004046096A2 NOVEL LIGANDS THAT ARE ANTAGONISTS OF RAF RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS 审中-公开
标题翻译：作为RAF受体拮抗剂的新型配体，其制备方法及其在人体和化妆品中的应用
公开(公告)号：WO2004046096A2
公开(公告)日：2004-06-03
申请号：PCT/EP0314860
申请日：2003-11-18
申请人： GALDERMA RES & DEV , DIAZ PHILIPPE , RAFFIN CATHERINE , BIADATTI THIBAUD
发明人： DIAZ PHILIPPE , RAFFIN CATHERINE , BIADATTI THIBAUD
IPC分类号： A61K31/19 , A61K31/195 , A61P17/00 , C07C63/36 , C07C63/64 , C07C63/66 , C07C65/11 , C07C65/19 , C07C65/28 , C07C65/34 , C07C65/38 , C07C69/76 , C07C229/18 , C07C229/38 , C07C229/52 , C07C233/54 , C07C235/38 , C07C235/42 , C07C235/78 , C07C259/10 , C07C271/28 , C07C323/62 , C07C391/02 , C07D213/30 , C07D213/79 , C07D213/80 , C07D333/16
CPC分类号： C07D213/79 , C07B2200/07 , C07C63/36 , C07C63/64 , C07C63/66 , C07C65/11 , C07C65/19 , C07C65/28 , C07C65/34 , C07C65/38 , C07C69/76 , C07C229/18 , C07C229/38 , C07C229/52 , C07C233/54 , C07C235/38 , C07C235/42 , C07C235/78 , C07C259/10 , C07C271/28 , C07C323/62 , C07C391/02 , C07C2602/10 , C07D213/30 , C07D213/80 , C07D333/16
摘要： The invention relates to novel compounds corresponding to formula (I) below: and to the method for preparing them, and to their use in pharmaceutical compositions intended for use in human or veterinary medicine, or alternatively in cosmetic compositions.
摘要翻译：本发明涉及对应于下式（I）的新化合物：及其制备方法及其在预期用于人或兽医药品或替代化妆品组合物的药物组合物中的用途。

4. 发明申请

WO00058281A1 SUBSTRATES FOR THIOREDOXIN REDUCTASE 审中-公开
标题翻译：硫代二氧化还原酶基质
公开(公告)号：WO00058281A1
公开(公告)日：2000-10-05
申请号：PCT/JP2000/002076
申请日：2000-03-31
IPC分类号： A61K31/166 , A61K31/167 , A61P39/06 , C07C391/02 , C07D293/04 , C12N9/02 , C12P9/00 , B01J31/12 , C07B31/00 , C09K15/32 , C12N9/00 , C12N9/04
CPC分类号： C07D293/04 , A61K31/166 , A61K31/167 , C07C391/02 , C12N9/0036 , C12P9/00
摘要： Substrates for thioredoxin reductase, containing compounds represented by general formula (1) or (1') (such as 2-phenyl-1,2-benzisoselenazol-3(2H)-one or open-ring derivatives thereof) (wherein R and R are each hydrogen, halogeno, trifluoromethyl, or the like; R is aryl, an aromatic heterocyclic group, or the like; R is hydrogen, hydroxyl, an -S- alpha -amino acid group, or the like; R is hydrogen or C1-C6 alkyl; Y is oxygen or sulfur; and n is an integer of 0 to 5, with the proviso that the selenium atom may be oxidized). These substrates are reduced by thioredoxin reductase in the presence of NADPH and enhance the peroxidase activity of thioredoxin reductase.
摘要翻译：含有由通式（1）或（1'）表示的化合物的硫氧还蛋白还原酶的底物（例如2-苯基-1,2-苯并异硒唑-3（2H） - 酮或其开环衍生物）（其中R 1 >和R 2各自为氢，卤素，三氟甲基等; R 3为芳基，芳族杂环基等; R 4为氢，羟基，-S-α-氨基酸基等; R 5为氢或C 1 -C 6烷基; Y为氧或硫; n为0〜5的整数，条件是硒原子可被氧化）。这些底物在NADPH存在下被硫氧还蛋白还原酶还原，并增强硫氧还蛋白还原酶的过氧化物酶活性。

5. 发明申请

WO9015043A3 PERFLUOROVINYL COMPOUNDS 审中-公开
标题翻译：全氟化合物
公开(公告)号：WO9015043A3
公开(公告)日：1991-03-21
申请号：PCT/US9003154
申请日：1990-06-04
申请人： DOW CHEMICAL CO
发明人： BABB DAVID A , CLEMENT KATHERINE S , EZZELL BOBBY R
IPC分类号： C07C41/01 , C07C22/08 , C07C41/18 , C07C43/17 , C07C43/174 , C07C43/225 , C07C65/21 , C07C69/92 , C07C323/20 , C07C391/00 , C07C391/02 , C07F5/02 , C07F7/12 , C07F9/50 , C08F16/14 , C08F16/24 , C08F28/00 , C08F28/02 , C08F30/04 , C07C323/09 , C08F16/12 , C08F128/04
CPC分类号： C07C43/17 , C07C22/08 , C07C43/225 , C07C65/21 , C07C69/92 , C07C2603/18
摘要： The present invention is directed to compounds having at least two perfluorovinyl groups and having a structure represented by the following formula (I): CF2=CF-X-R-(X-CF=CF2)m, wherein R represents an unsubstituted or inertly substituted hydrocarbyl group; each X is independently selected from the group consisting of groups having at least one non-carbon atom between R and -CF=CF2; and m is an integer of from 1 to 3. Polymers formed from such compounds are also prepared. The compounds are preferably prepared by a process comprising the steps of: (a) forming a salt having anion corresponding to a compound of the following formula (II): HX-R-(XH)m, wherein X, R and m are as defined for formula (I); (b) reacting the salt formed in step (a) with a 1,2-dihalo-1,1,2, 2-tetrafluoroethane wherein the halo groups are iodine, bromine, chlorine or mixtures thereof, at least one halo group being bromine or iodine, to form a compound of the following formula (III): Z-CF2CF2-X-R-(X-CF2CF2-Z)m, wherein X, R and m are as defined for formula (I) and each Z is independently iodine or bromine; and (c) eliminating the halogen atoms represented by Z to form the perfluorovinyl compound represented by formula (I).

6. 发明申请

WO2020071782A1 칼코겐계 디아민, 이로부터 형성된 폴리아믹산과 폴리이미드, 상기 폴리이미드를 포함한 폴리이미드 필름 审中-公开
公开(公告)号：WO2020071782A1
公开(公告)日：2020-04-09
申请号：PCT/KR2019/012904
申请日：2019-10-02
申请人： 한국과학기술연구원
发明人： 김현일 , 고문주 , 구본철 , 장세규 , 유재상 , 유남호
IPC分类号： C08G73/10 , C07C391/02 , C07C395/00 , C08L79/08 , C08J5/18
摘要： 본 발명은 하기 화학식 1로 표시되는 칼코겐계 디아민과, 산 이무수물(acid dianhydride)의 중합 반응 생성물인 폴리아믹산, 이로부터 얻은 폴리이미드, 폴리이미드 필름 및 칼코겐계 디아민을 제공한다. [화학식 1] 상기 화학식 1에서, X 1 은 셀레늄(Se) 이산화셀레늄(SeO 2 ), 텔루늄(Te), 이산화텔루늄(TeO 2 ) 또는 그 조합물이고, Ar 1 및 Ar 2 는 각각 독립적으로 하기 화학식 1-1 내지 1-3로 이루어지는 그룹으로부터 선택되고, [화학식 1-1] [화학식 1-2] [화학식 1-3] 화학식 1-1 내지 1-3 중, *는 결합위치를 나타내고, R 1 내지 R 4 는 각각 독립적으로 수소, 불소, 탄소수 1 내지 30의 알킬기 및 탄소수 1 내지 30의 퍼플루오로알킬기로 이루어지는 그룹으로부터 선택된다.

7. 发明申请

WO2018072291A1 含硒聚酰亚胺聚合物及其制备方法和应用审中-公开
公开(公告)号：WO2018072291A1
公开(公告)日：2018-04-26
申请号：PCT/CN2016/110235
申请日：2016-12-16
申请人：苏州大学
发明人：朱健 , 李琪龙 , 丁春来 , 姜慧楠 , 朱秀林
IPC分类号： C08G73/10 , C07C391/02 , C08J5/18
摘要：一种高折光指数的含硒聚酰亚胺的制备方法及其应用，方法包括：(1)将硒醚二胺单体与二酸酐单体聚合得到含硒聚酰胺酸；(2)将步骤(1)中得到的含硒聚酰胺酸经热亚胺化得到含硒聚酰亚胺聚合物。聚酰亚胺中引入硒元素能够提高折光指数，折光指数值为1.7-1.82，极大的改善了现有聚酰亚胺材料折光指数不高的缺陷，使其在光学领域的应用得到延伸。

8. 发明申请

WO2007134537A1 一类含杂原子的有机化合物及其在单活性中心齐格勒-纳塔催化剂中的应用审中-公开
公开(公告)号：WO2007134537A1
公开(公告)日：2007-11-29
申请号：PCT/CN2007/001648
申请日：2007-05-21
申请人：中国科学院上海有机化学研究所 , 唐勇 , 杨小红 , 刘博 , 孙秀丽 , 马志 , 高原 , 王聪
发明人：唐勇 , 杨小红 , 刘博 , 孙秀丽 , 马志 , 高原 , 王聪
IPC分类号： C07C225/22 , C07C321/24 , C07C391/02 , C07D215/40 , C07D307/91 , C08F4/645 , C08F10/02 , C08F10/04 , C08F2/34
CPC分类号： C08F10/02 , C07C211/45 , C07C225/14 , C07C225/16 , C07C225/18 , C07C323/25 , C07C323/36 , C07C323/37 , C07C391/02 , C07D215/40 , C07D307/91 , C08F4/65912 , C08F10/00 , C08F110/02 , C08F210/16 , C08F4/6543 , C08F4/64127 , C08F2500/03 , C08F210/14 , C08F4/62124
摘要： Organic compounds containing heteroatoms and their use in preparing Ziegler-Natta (Z-N) catalyst with single activation center. The Z-N olefin polymerization catalyst is prepared by adding organic or inorganic solid carrier or compound of them which is pre-activated by heating or pre-treated chemically, organic compound containing heteroatoms and metallic compound into magnesium compound/tetrahydrofuran solution. The Z-N olefin polymerization catalyst prepared in the present invention is fluidizable powder and can prepare ethene homopolymer and copolymer of controllable construction with high catalytic activity, during homo-polymerization and combined polymerization with alpha-olefin of C3~C18 under action of catalyst promoter such as alkyl aluminum, alkyl aluminoxane and so on.

9. 发明申请

WO2006077888A1 新規な縮合多環芳香族化合物およびその利用审中-公开
标题翻译：新型稠合多环芳烃化合物及其用途
公开(公告)号：WO2006077888A1
公开(公告)日：2006-07-27
申请号：PCT/JP2006/300654
申请日：2006-01-18
申请人：国立大学法人広島大学 , 瀧宮和男 , 功刀義人 , 近田安史
发明人：瀧宮和男 , 功刀義人 , 近田安史
IPC分类号： C07D495/04 , C07D517/04 , C07C391/02 , H01L29/786 , H01L51/30 , H01L51/05 , H01L51/50 , G09F9/30 , H01L27/32
CPC分类号： C07D513/04 , C07C391/02 , C09B57/00 , H01L51/0074 , H01L51/0541 , H01L51/0545
摘要：　本発明は、高い電界効果移動度と、高いオン／オフ電流比の双方を満足する有機半導体材料を備えた有機半導体デバイスを実現することを課題とし、有機半導体材料として要求される高い電界効果移動度と、高いオン／オフ電流比の双方を満足する新規な縮合多環芳香族化合物を提供するものである。
摘要翻译：一种包含满足高电子场效应迁移率和高导通/截止电流比要求的有机半导体材料的有机半导体器件。提供了一种满足有机半导体材料所需的高电子场效应迁移率和高导通/截止电流比的新型稠合多环芳族化合物。

10. 发明申请

WO03101945A8 LIGANDS THAT ARE INHIBITORS OF THE RAR RECEPTORS 审中-公开
标题翻译： RAR受体抑制剂的配体
公开(公告)号：WO03101945A8
公开(公告)日：2004-11-25
申请号：PCT/EP0305555
申请日：2003-05-27
申请人： GALDERMA RES & DEV , BIADATTI THIBAUD , COLLETTE PASCAL
发明人： BIADATTI THIBAUD , COLLETTE PASCAL
IPC分类号： A61K8/368 , A61K8/58 , A61P3/04 , A61P3/06 , A61P3/10 , A61P17/00 , A61P27/02 , A61Q19/00 , A61Q19/08 , C07C65/26 , C07C65/40 , C07C229/38 , C07C233/75 , C07C235/42 , C07C237/30 , C07C323/62 , C07C391/02 , A61K7/48 , A61K31/192
CPC分类号： A61K8/19 , A61K8/27 , A61K8/368 , A61K8/4926 , A61K8/58 , A61K8/69 , A61Q19/00 , A61Q19/007 , A61Q19/08 , C07C65/26 , C07C65/40 , C07C229/38 , C07C233/75 , C07C235/42 , C07C237/30 , C07C323/62 , C07C391/02 , C07C2602/10
摘要： Novel ligands that are inhibitors of the RAR receptors, process for preparing them and use thereof in human medicine and in cosmetics. The invention relates to novel bicyclic compounds corresponding to the general formula (I) and to the method for preparing them, and to their use in pharmaceutical compositions intended for use in human or veterinary medicine, or alternatively in cosmetic compositions.
摘要翻译：作为RAR受体的抑制剂的新型配体，其制备方法及其在人类医学和化妆品中的应用。本发明涉及对应于通式（I）的新型双环化合物及其制备方法，以及它们在预期用于人或兽医药品或替代化妆品组合物的药物组合物中的用途。

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