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    • 4. 发明申请
    • AMINOPHENOL DERIVATIVES AND THEIR USE IN OXIDATIVE HAIR DYES
    • 氨基酚衍生物和它们在氧化染发剂
    • WO1997031886A1
    • 1997-09-04
    • PCT/EP1997000767
    • 1997-02-19
    • HENKEL KOMMANDITGESELLSCHAFT AUF AKTIENROSE, DavidHÖFFKES, HorstMEINIGKE, Bernd
    • HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
    • C07C215/80
    • A61Q5/10A61K8/415C07C215/80C07C217/84C07C229/44D06P1/32D06P3/08
    • Described are aminophenol derivatives of general formula (I) in which one of the two groups R and R is hydrogen and the other is hydrogen, chlorine or fluorine; one of the two groups R and R is hydrogen, a C1-4-alkoxy group, a C1-4-alkyl group, a C1-4-hydroxyalkyl group, preferably with a terminal hydroxy group or halogen and the other is one of the groups: -O-CH2-CH=CH2, -CH=CH-COOX in which X is hydrogen or a physiologically tolerable inorganic or organic cation and, in the case when the group concerned is R , the group (a) and, in the case when the group concerned is R , (b), in which -A- in each case is one of the groups -(CH2)x- in which x = 1 to 4, -O-(CH2)y-O- in which y = 1 to 4, -O-(CnH2n-z(OH)z)-O- in which n = 1 to 10 and z = 1 or, when n is greater than or equal to 3, z = 2, -O-(C2H4-O)u- in which u = 1 to 4 and -O-(C3H6-O)v- in which v is 1 to 4. Such derivatives are particularly suitable for use as developers in oxidative dyes for dyeing keratin fibres. Brilliant hues with a high degree of fastness are obtained with the usual coupling agents, particularly when dyeing hair.
    • 通式(I)的氨基苯酚衍生物,其中两个基团的一个R <1>和R <2>为氢且另一个基团表示氢,氯或氟,和两个基团的一个R <3>和 [R <4>为氢,C 1-4烷氧基,C 1-4烷基,C 1-4羟烷基,优选为羟基封端的,或卤素,并且另一个基团表示基团之一:-O - CH2-CH = CH 2,-CH = CH-COOX,其中,X代表氢或生理上可耐受的无机或有机阳离子,以及用于它是基团R <3>是一组的情况下(a)中 和在于它是基团R的情况下<4>是基团(b),其中-A-在每种情况下表示基团中的一个 - (CH 2)x,其中x = 1 - 4,-O - (CH2)yO-其中y = 1-4,-O-(为CnH2n-Z(OH)z的)-O-,其中n = 1 - 10且z = 1,或者当n大于或等于3,2 = ,-O-(C 2 H 4 O)的u,其中u = 1-4,-O-(C 3 H 6 O)v - ,其中v = 1-4,突出地一 在用于着色角蛋白纤维的着色剂的氧化显影剂LS部件。 具体地讲,毛发染色色调辉煌当高坚牢度与常规成色剂组分获得。
    • 7. 发明申请
    • PROCESS FOR PRODUCING 4,6-DIAMINORESORCINOL OR ITS SALTS
    • 生产4,6-二氨基辛醇或其盐的方法
    • WO99037601A1
    • 1999-07-29
    • PCT/JP1999/000268
    • 1999-01-25
    • C07C213/02C07C215/80B01J23/42B01J23/44B01J23/64C07C213/10
    • C07C213/02C07C215/80
    • A process for producing 4,6-diaminoresorcinol or its salt which comprises reducing by hydrogenation in the presence of a metallic catalyst 4,6-bis(substituted)phenylazoresorcinol represented by general formula (1) (for example, 4,6-bisphenylazoresorcinol) to give 4,6-diaminoresorcinol or its salts. In said formula, represent each halogeno, C1-5 alkyl, hydroxycarbonyl or C1-5 alkoxy, provided that two or more Rs may be either the same or different from each other; and n is 0 or an integer of from 1 to 5; characterized by using an aliphatic nitrile compound (for example, acetonitrile) as a solvent, or effecting the reduction by using at least one organic solvent selected from among aliphatic nitrile compounds, aliphatic C3-5 alcohols, dioxane, ethylene glycol monomethyl ether, etc. in the presence of a filter aid (for example, active carbon). This process makes it possible to easily produce highly pure 4,6-diaminoresorcinol from 4,6-bis(substituted)-phenylazoresorcinol at a high yield.
    • 一种制备4,6-二氨基间苯二酚或其盐的方法,其包括在通式(1)表示的金属催化剂4,6-双(取代的)苯基次氮基间苯二酚(例如4,6-双苯​​基次氮基间苯二酚)的存在下氢化还原, 得到4,6-二氨基间苯二酚或其盐。 在所述式中,表示每个卤代C 1-5烷基,羟基羰基或C 1-5烷氧基,条件是两个或多个R 3可以彼此相同或不同; n为0或1〜5的整数, 其特征在于使用脂族腈化合物(例如乙腈)作为溶剂,或者使用至少一种选自脂肪族腈化合物,脂肪族C3-5醇,二恶烷,乙二醇单甲醚等的有机溶剂进行还原。 在助滤剂(例如活性炭)的存在下。 该方法可以从4,6-双(取代的) - 苯基次氮基间苯二酚以高产率容易地制备高纯度的4,6-二氨基间苯二酚。