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1. 发明申请

WO2023278583A1 DIGESTIVE SYSTEM SIMULATION AND PACING 审中-公开
公开(公告)号：WO2023278583A1
公开(公告)日：2023-01-05
申请号：PCT/US2022/035531
申请日：2022-06-29
申请人： VEKTOR MEDICAL, INC.
发明人： KRUMMEN, Robert Joseph , KRUMMEN, Paul Jerome , KAMRAVA, Allen
IPC分类号： A61B5/285 , A61N1/38 , A61B5/392 , G06F30/27 , G16H10/60 , G16H50/50
摘要： Methods and systems for analyzing and treating digestive disorders (including gastrointestinal disorders) are provided. A system provides various technologies (e.g., machine learning and simulations) to support such analysis and treatment of digestive disorders. The system may employ computational modeling of the digestive system based on anatomical characteristics and electrical characteristics of the digestive system to simulate motion and electrical activity. The system generates representations of the electrical activity such as an electrogastrogram and generates mappings of the representations to characteristic values of the simulations. The system may train a machine learning model based on the mappings. When treating a patient, the mappings and/or the machine learning model may be employed to identify a patient characteristic based on a patient representation of electrical activity collected from the patient.

2. 发明申请

WO2020263836A1 WEARABLE DEVICE CAPABLE OF INDUCING ELECTRO-MUSCULAR INCAPACITATION 审中-公开
公开(公告)号：WO2020263836A1
公开(公告)日：2020-12-30
申请号：PCT/US2020/039149
申请日：2020-06-23
申请人： GULLOTTI, William
发明人： GULLOTTI, William
IPC分类号： F41H13/00 , H05C1/00 , A41D19/015 , A61N1/38 , G01P15/00
摘要： A hand-wearable device capable of electro muscular incapacitation device is disclosed. The device may comprise a glove portion including a back side and a palm side, a stun hardware component including a charging port, a rechargeable battery, and a capacitor. First and second terminals may be positioned on the back side of the glove portion and electrically connected to the stun hardware component. The glove portion may encompass a traditional five- fingered glove, cycling glove, lifting glove, or gauntlet. In addition, the glove portion may comprise a cuff or bracer. When the hand-

3. 发明申请

WO2017127548A1 DEVICES FOR WIRELESSLY RECHARGING A RECHARGEABLE BATTERY OF AN IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：用于无线充电可充电电池的可充电电池的设备
公开(公告)号：WO2017127548A1
公开(公告)日：2017-07-27
申请号：PCT/US2017/014139
申请日：2017-01-19
申请人： CARDIAC PACEMAKERS, INC. , NDSU RESEARCH FOUNDATION
发明人： MAILE, Keith R. , BRAATEN, Benjamin , EWERT, Daniel
IPC分类号： A61N1/375 , A61N1/378 , A61N1/36 , A61N1/38 , A61N1/372 , H01Q1/38 , H01Q3/24 , H01Q9/42
CPC分类号： A61N1/3787 , A61N1/36 , A61N1/362 , A61N1/37223 , A61N1/37229 , A61N1/3756
摘要： Implantable medical devices such as leadless cardiac pacemakers may include a rechargeable battery, and a receiving antenna for receiving radiative energy from an external transmitter. Energy captured by the receiving antenna of the implantable medical device may be converted into electrical energy that may be used to recharge the rechargeable battery of the implantable medical device. Since the rechargeable battery does not have to initially store sufficient energy to power the implantable medical device over its entire useful life, the battery itself and thus the implanted medical device can be made smaller while still achieving device longevity expectations.
摘要翻译：诸如无引线心脏起搏器的植入式医疗设备可以包括可充电电池和用于从外部发射器接收辐射能量的接收天线。由可植入医疗装置的接收天线捕获的能量可以被转换成可用于对可植入医疗装置的可再充电电池进行再充电的电能。由于可充电电池在其整个使用寿命中不必首先存储足够的能量来为植入式医疗装置供电，因此电池本身以及因此植入的医疗装置可以制造得更小，同时仍然实现装置寿命预期。

4. 发明申请

WO2011139596A2 METHOD AND DEVICE FOR THREE-STAGE ATRIAL CARDIOVERSION THERAPY 审中-公开
标题翻译：用于三期ATRIAL CARDIOVERSION治疗的方法和装置
公开(公告)号：WO2011139596A2
公开(公告)日：2011-11-10
申请号：PCT/US2011/033547
申请日：2011-04-22
申请人： THE WASHINGTON UNIVERSITY , EFIMOV, Igor, R. , FEDOROV, Vadim, V. , RIPPLINGER, Crystal, M. , FOYIL, Kelley, V. , AMBROSI, Christina, M.
发明人： EFIMOV, Igor, R. , FEDOROV, Vadim, V. , RIPPLINGER, Crystal, M. , FOYIL, Kelley, V. , AMBROSI, Christina, M.
IPC分类号： A61N1/38 , A61N1/05 , A61N1/372 , A61N1/36
CPC分类号： A61N1/3956 , A61N1/3624 , A61N1/3906 , A61N1/395 , A61N1/3987
摘要： Methods and apparatus for a three-stage atrial cardioversion therapy that treats atrial arrhythmias within pain tolerance thresholds of a patient. An implantable therapy generator adapted to generate and selectively deliver a three-stage atrial cardioversion therapy and at least two leads operably each having at least one electrode adapted to be positioned proximate the atrium of the patient. The device is programmed with a set of therapy parameters for delivering a three-stage atrial cardioversion therapy to the patient via both a far-field configuration and a near-field configuration of the electrodes upon detection of an atrial arrhythmia. The three-stage atrial cardioversion therapy includes a first stage for unpinning of one or more singularities associated with an atrial arrhythmia, a second stage for anti-repinning of the one or more singularities associated with the atrial arrhythmia, both of which are delivered via the far-field configuration of the electrodes, and a third stage for extinguishing of the one or more singularities associated with the atrial arrhythmia delivered via the near-field configuration of the electrodes.
摘要翻译：用于治疗患者疼痛耐受阈值内心房心律失常的三期心房心脏复律治疗方法和装置。一种植入式治疗发生器，其适于产生和选择性地递送三阶段心房复律治疗和至少两个可操作的引线，每个引线具有至少一个适于定位在患者的心房附近的电极。该装置被编程有一组治疗参数，用于在检测到房性心律失常时通过远场配置和电极的近场配置向患者传送三级心房复律治疗。三级心房复律治疗包括用于解除与心房心律失常相关的一个或多个奇异点的第一阶段，用于抗心律失常相关的一个或多个奇点的第二阶段，其中两个都通过电极的远场结构，以及用于熄灭与通过电极的近场结构输送的心房心律失常相关联的一个或多个奇异点的第三阶段。

5. 发明申请

WO2009045610A1 AUTOMATIC DETERMINATION OF T-SHOCK VULNERABLE WINDOW 审中-公开
标题翻译：自动确定T-SHOCK VULNERABLE WINDOW
公开(公告)号：WO2009045610A1
公开(公告)日：2009-04-09
申请号：PCT/US2008/071144
申请日：2008-09-30
申请人： MEDTRONIC, INC , GILLBERG, Jeffrey M. , BELK, Paul A. , CAO, Jian , SWERDLOW, Charles D.
发明人： GILLBERG, Jeffrey M. , BELK, Paul A. , CAO, Jian , SWERDLOW, Charles D.
IPC分类号： A61N1/39 , A61N1/38
CPC分类号： A61N1/3987 , A61N1/385 , A61N1/3943 , A61N1/3962
摘要： A method and apparatus for determining a T-wave shock interval sense a cardiac electrogram (EGM) signal comprising a T-wave signal. A T-wave center is determined from the EGM signal, and a T-wave shock interval is determined in response to determining the T-wave center. A T-wave shock is delivered at the T-wave shock interval computed based on the T-wave center.
摘要翻译：一种用于确定T波冲击间隔的方法和装置，其感测包括T波信号的心电图（EGM）信号。从EGM信号确定T波中心，并且响应于确定T波中心来确定T波冲击间隔。在基于T波中心计算出的T波冲击时间间隔内传递T波冲击。

6. 发明申请

WO2008153450A1 AN IMPLANTABLE MEDICAL DEVICE AND A METHOD COMPRISING MEANS FOR DETECTING AND CLASSIFYING VENTRICULAR TACHYARRHYTMIAS 审中-公开
标题翻译：一种可植入医疗装置和一种包含检测和分类静脉曲张虫的手段的方法
公开(公告)号：WO2008153450A1
公开(公告)日：2008-12-18
申请号：PCT/SE2007/000581
申请日：2007-06-13
申请人： ST. JUDE MEDICAL AB , HOLMSTRÖM, Nils , BLOMQVIST, Andreas , HEDBERG, Sven-Erik , ÖHLANDER, Malin
发明人： HOLMSTRÖM, Nils , BLOMQVIST, Andreas , HEDBERG, Sven-Erik , ÖHLANDER, Malin
IPC分类号： A61N1/362 , A61N1/365 , A61N1/37 , A61N1/372 , A61N1/38
CPC分类号： A61N1/3702 , A61B5/0464 , A61B5/053 , A61B5/7264
摘要： The invention relates to ventricular tachyarrhythmia detection and classification. Upon detection of a ventricular tachyarrhythmia based on an electrocardiogram signal, cardiogenic impedance data representative of ventricular volume dynamics are collected and used for classifying the detected tachyarrhythmia as stable or unstable. In the latter case but typically not in the former case, defibrillation shocks or other forms of therapy are applied to combat the unstable ventricular tachyarrhythmia.
摘要翻译：本发明涉及室性快速性心律失常检测和分类。在基于心电图信号检测到心室快速性心律失常时，收集代表心室体积动力学的心源阻抗数据，并用于将检测到的快速性心律失常分类为稳定或不稳定。在后一种情况下，但通常不是在前一种情况下，应用除颤电击或其他形式的治疗来对抗不稳定性室性快速性心律失常。

7. 发明申请

WO03011388A3 NEUROSTIMULATION UNIT FOR IMMOBILIZING THE HEART DURING CARDIOSURGICAL OPERATIONS 审中-公开
标题翻译： NEURO刺激单元对心脏期间的操作心脏手术固定化
公开(公告)号：WO03011388A3
公开(公告)日：2003-06-05
申请号：PCT/EP0208443
申请日：2002-07-29
申请人： IMPELLA CARDIOTECH AG , SCHAUERTE PATRICK
发明人： SCHAUERTE PATRICK
IPC分类号： A61N1/36 , A61N1/38
CPC分类号： A61N1/36114 , A61N1/385
摘要： The invention relates to a device for temporary reduction of heart movement during an operation, more particularly a heart operation, comprising a neurostimulation unit (20) for stimulation of the nerves (3) that slow down heart frequency, said unit including at least one electrode device (1) with at least one stimulation pole (2), wherein a control unit (19) connected to the neurostimulation device (20) is provided. Said control device has a first input device (26) for inputting a degree of immobilization and is configured to influence the operating state of the neurostimulation device (20) depending on the previously set degree of immobilization.
摘要翻译：装置，用于暂时降低手术期间心脏运动，特别是心脏手术，具有神经刺激装置（20），用于刺激心脏速率verlangsamender神经（3），包括至少一个电极装置（1）与至少一种刺激极（2），一个与提供神经刺激装置相连接（20），控制装置（19），其具有用于提供Immobilisierungsgrades和用于影响神经刺激装置（20）的操作状态在所述预定固定依赖性形成的第一设定装置（26）。

8. 发明申请

WO00066222A1 METHOD AND APPARATUS FOR TREATMENT OF CARDIAC ELECTROMECHANICAL DISSOCIATION 审中-公开
标题翻译：用于治疗心脏电生理分解的方法和装置
公开(公告)号：WO00066222A1
公开(公告)日：2000-11-09
申请号：PCT/US2000/011484
申请日：2000-04-28
IPC分类号： A61N1/38 , A61N1/39
CPC分类号： A61N1/3962 , A61N1/385
摘要： An apparatus and method for treating post-defibrillation electromechanical dissociation ("EMD"). A first embodiment comprises an implantable defibrillator, which may include cardioversion and pacemaker capabilities, which has the capability of detecting and treating post defibrillation EMD. The stimulator/defibrillator has one or more leads with electrodes. At least one electrode for defibrillation may be an endocardial or epicardial electrode or other suitable defibrillation electrode. A sense circuit senses the electrical condition of the heart of the patient. A hemodynamic sensor senses a parameter correlated to the state of blood flow. The cardiac stimulator/defibrillater detects ventricular tachyarrhythmia including fibrillation and terminates ventricular tachyarrhythmia. After termination of the ventricular tachyarrhythmia, the stimulator/defibrillator can detect the presence of electrical rhythm in the heart correlated, however, with inadequate blood flow to sustain life. Under such conditions, the device provides an output to stimulate the heart to overcome electromechanical dissociation and restore adequate blood flow. The device may also be an external therapy device, as part of, or in conjunction with an external defibrillator. The method for treating the heart to restore blood flow where electromechanical dissociation occurs after termination of a ventricular tachyarrhythmia of ventricular fibrillation comprises identifying electromechanical disassociation after termination of a ventricular tachyarrhythmia or a fibrillation and providing electrical therapy, the therapy comprising a series of packets of electrical pulses.
摘要翻译：一种用于治疗除颤后机电解离（“EMD”）的装置和方法。第一实施例包括可植入除颤器，其可以包括心脏复律和起搏器能力，其具有检测和治疗除颤后EMD的能力。刺激器/除颤器具有一个或多个具有电极的引线。用于除颤的至少一个电极可以是心内膜或心外膜电极或其它合适的除颤电极。感测电路感测患者心脏的电气状况。血液动力学传感器检测与血流状态相关的参数。心脏刺激器/去纤颤器检测心律失常包括颤动，并终止室性快速性心律失常。在室性快速性心律失常终止后，刺激器/除颤器可以检测到心脏中电气节律的存在相关，然而血液流量不足以维持生命。在这种条件下，该装置提供一个输出来刺激心脏以克服机电解离并恢复足够的血流量。该装置也可以是外部治疗装置，作为外部去纤颤器的一部分或与其结合使用。用于治疗心脏恢复血流的方法，其中机电解离发生在心室颤动的室性快速性心律失常终止之后发生，包括在终止室性快速性心律失常或原纤维化之后鉴定机电解离，并提供电疗法，该治疗包括一系列电气脉冲。

9. 发明申请

WO2020250074A1 DEVICE FOR CARDIAC ELECTROPHYSIOLOGY PROCEDURE 审中-公开
公开(公告)号：WO2020250074A1
公开(公告)日：2020-12-17
申请号：PCT/IB2020/055111
申请日：2020-05-29
申请人： IONESCU, Bogdan
发明人： IONESCU, Bogdan
IPC分类号： A61B18/14 , A61N1/38 , A61B5/0428 , A61B5/0402 , A61M25/00 , A61B5/042 , A61B5/00 , A61N1/05
摘要： A cardiac electrophysiology device part of a catheter device or of a cardiac implantable device comprising a plurality of electrodes which are connected via a selector switch over a resistor to a neutral electrode. Voltage and current at one of the electrodes are measured to set the site and the timing of channelling current out from the heart optionally by the electrophysiology therapy.

10. 发明申请

WO2020077113A1 WEARABLE MEDICAL DEVICE WITH DISPOSABLE AND REUSABLE COMPONENTS 审中-公开
公开(公告)号：WO2020077113A1
公开(公告)日：2020-04-16
申请号：PCT/US2019/055678
申请日：2019-10-10
申请人： ELEMENT SCIENCE, INC.
发明人： FARINO, Kevin, M. , BAHNEY, Timothy , STADTLANDER, William , DHULDHOYA, Jay , AFSHAR, Pedram , KUMAR, Uday, N. , DINGER, Maarten , MARANGI, Riley
IPC分类号： A61B5/0402 , A61B5/0468 , A61N1/04 , A61N1/36 , A61N1/38 , A61N1/39
摘要： Embodiments of a wearable device are provided. The wearable device comprises a resuable component and a disposable component. The disposable component comprises a patient engagement substrate comprising adhesive on a bottom side, an electrode on the bottom side, a disposable component electrical connector, and a disposable component mechanical connector. The reusable component comprises a plurality of sealed housings mechanically coupled to each other and movable with respect to each other, each of the plurality of housings containing one or more of a capacitor and a controller, a reusable component mechanical connector adapted to removably connect to the disposable component mechanical connector, and a reusable component electrical connector adapted to removably connect to the disposable component electrical connector. The device can comprise a cardiopulmonary physiologic monitor or a automatic external defibrillator, among other types of devices.

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