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1. 发明申请

WO01071415A1 MATERIAL FOR OCULAR LENS 审中-公开
标题翻译： OCULAR镜片材质
公开(公告)号：WO01071415A1
公开(公告)日：2001-09-27
申请号：PCT/JP2001/002221
申请日：2001-03-21
IPC分类号： A61L27/14 , A61L27/16 , C08F2/46 , C08F2/48 , C08F2/50 , C08F230/08 , C08F283/12 , C08F290/06 , C08F290/14 , C08L51/08 , G02B1/04 , G02C7/04 , A61F2/16 , C08J5/00
CPC分类号： A61L27/16 , A61L27/14 , A61L2430/16 , C08F230/08 , C08F283/12 , C08F290/068 , C08F290/148 , C08L51/085 , G02B1/043 , Y10S525/903 , Y10S525/906 , Y10S525/936 , C08L2666/04 , C08L2666/02
摘要： An ocular-lens material which comprises a copolymer obtained by polymerizing polymerizable ingredients consisting mainly of a polysiloxane macromonomer (A), a silicon-containing alkyl methacrylate (B), hydrophilic monomers (C) consisting of NVP (C-1) and other hydrophilic monomer (C-2), other monomer(s) (D), and low-molecular crosslinking monomers (E) consisting of a crosslinking monomer (E-1) having an acryloyl, vinyl, or allyl group and a methacryloyl group and a crosslinking monomer (E-2) having two or more methacryloyl groups by the casting method with heating and ultraviolet irradiation, wherein [(A)+(B)]/(C) (by weight) is 30/70 to 70/30, (A)/(B) is 25/75 to 75/25, (C-1)/(C-2) is 50/50 to 100/0, and (D) accounts for 0 to 20 wt.% of the polymerizable ingredients. The ocular-lens material has high permeability to oxygen and high mechanical strength. The surface of the material has excellent wettability by water and low-friction properties.
摘要翻译：一种眼透镜材料，其包含通过聚合主要由聚硅氧烷大分子单体（A），含硅烷基甲基丙烯酸酯（B），由NVP（C-1）组成的亲水性单体（C））和其它亲水性单体（C-2），其它单体（D）和由具有丙烯酰基，乙烯基或烯丙基的交联单体（E-1）和甲基丙烯酰基组成的低分子量交联单体（E）其中[（A）+（B）] /（C）（重量）为30/70〜70/30，通过流延法，通过加热和紫外线照射具有两个以上甲基丙烯酰基的交联单体（E-2）（A）/（B）为25/75〜75/25，（C-1）/（C-2）为50/50〜100/0，（D）占0〜20重量％可聚合成分。眼透镜材料对氧的渗透性高，机械强度高。该材料的表面具有优异的水润湿性和低摩擦性能。

2. 发明申请

WO1996031792A1 EXTENDED WEAR OPHTHALMIC LENS 审中-公开
标题翻译：延伸耐磨透镜
公开(公告)号：WO1996031792A1
公开(公告)日：1996-10-10
申请号：PCT/EP1996001265
申请日：1996-03-22
申请人： CIBA-GEIGY AG , COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION , NICOLSON, Paul, Clement , BARON, Richard, Carlton , CHABRECEK, Peter , COURT, John , DOMSCHKE, Angelika , GRIESSER, Hans, Jörg , HO, Arthur , HÖPKEN, Jens , LAYCOCK, Bronwyn, Glenice , LIU, Qin , LOHMANN, Dieter , MEIJS, Gordon, Francis , PAPASPILIOTOPOULOS, Eric , RIFFLE, Judy, Smith , SCHINDHELM, Klaus , SWEENEY, Deborah , TERRY, Wilson, Leonard, Jr. , VOGT, Jürgen , WINTERTON, Lynn, Cook
发明人： CIBA-GEIGY AG , COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
IPC分类号： G02B01/04
CPC分类号： G02C7/049 , A61L27/26 , A61L27/34 , A61L2430/16 , B05D1/62 , B29C39/42 , B29C71/00 , B29D11/00076 , B29L2011/0041 , C08G18/10 , C08G18/4833 , C08G18/5015 , C08G18/61 , C08G18/672 , C08G18/8116 , C08G18/8175 , G02B1/043 , Y10S525/903 , Y10S525/936 , Y10S525/937 , C08L51/085 , C08L51/08 , C08L33/00 , C08L83/04 , C08L39/06 , C08G18/63 , C08G18/48
摘要： An ophthalmic lens is disclosed which is suited for extended-wear periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of an oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.
摘要翻译：公开了一种眼科镜片，其适用于眼睛的至少一天的延长磨损期，而没有临床显着量的角膜肿胀并且没有实质的佩戴者不适。透镜具有透氧性和离子或水渗透性的平衡，离子或水渗透性足以提供良好的眼内运动，使得透镜和眼睛之间发生良好的泪液交换。优选的透镜是含量大分子单体和离子单体的共聚产物。本发明包括长期佩戴的隐形眼镜，其包括具有从内表面延伸到外表面的氧透过和离子传播途径的核心。

3. 发明申请

WO9112293A2 HOT MELT ADHESIVE FORMULATION HEAT CURABLE BY EPOXY CROSSLINKING 审中-公开
标题翻译：热熔胶粘剂配方可通过环氧交联固化
公开(公告)号：WO9112293A2
公开(公告)日：1991-08-22
申请号：PCT/US9100815
申请日：1991-02-06
申请人： EXXON CHEMICAL PATENTS INC
发明人： TSE MUN FU
IPC分类号： C09J123/08 , C09J123/26
CPC分类号： C09J123/26 , C08L2666/22 , C08L2666/34 , C09J123/08 , Y10S525/936
摘要： A heat curable hot melt adhesive system is disclosed. The system uses an epoxy-crosslinking ethylene polymer component, a tackifier compatible therewith and an epoxy crosslinking agent having an epoxide functionality of at least 2. The ethylene polymer component may be either an ethylene copolymer of an alpha , beta -ethylenically unsaturated carboxylic acid, or an ethylene copolymer of an ethylenically unsaturated alcohol used in combination with a dicarboxylic acid anhydride. The dicarboxylic acid anhydride and/or the epoxy can be encapsulated to inhibit premature crosslinking. The formulation is applied to a substrate surface as a hot melt at a moderate temperature, and subsequently cured by heating the adhesive composition to a higher curing temperature.

4. 发明申请

WO1988006883A1 PAUCILAMELLAR LIPID VESICLES 审中-公开
标题翻译： PAULILELLELLAR脂肪虫
公开(公告)号：WO1988006883A1
公开(公告)日：1988-09-22
申请号：PCT/US1988000723
申请日：1988-03-08
申请人： MICRO VESICULAR SYSTEMS, INC.
发明人： MICRO VESICULAR SYSTEMS, INC. , WALLACH, Donald, F., H.
IPC分类号： A61K09/50
CPC分类号： A61K9/1272 , A61K9/1277 , C11D17/0021 , C11D17/0026 , Y10S424/10 , Y10S424/812 , Y10S436/829 , Y10S514/963 , Y10S525/936 , Y10T428/2984
摘要： A new method of producing paucilamellar lipid vesicles has been developed. The vesicles are made of non-phospholipid surfactants. The paucilamellar lipid vesicles have 2-8 lipid bilayers surrounding a central cavity which may be filled with either an aqueous-based solution or an oil or wax.
摘要翻译：已经开发了一种新的生产微囊脂质囊泡的方法。囊泡由非磷脂表面活性剂制成。薄膜脂质囊泡具有围绕中心腔的2-8个脂质双层，其可以用水性溶液或油或蜡填充。

5. 发明申请

WO2005061017A3 ELECTRICALLY CONDUCTIVE ADHESIVE HYDROGELS WITH SOLUBILIZER 审中-公开
标题翻译：具有增溶剂的导电粘合剂水凝胶
公开(公告)号：WO2005061017A3
公开(公告)日：2005-12-01
申请号：PCT/US2004029258
申请日：2004-09-08
申请人： KIMBERLY CLARK CO , YAHIAOUI ALI , KELLER CARON , BORDERS RICHARD ARNOLD
发明人： YAHIAOUI ALI , KELLER CARON , BORDERS RICHARD ARNOLD
IPC分类号： A61K47/40 , A61L31/14 , C09J9/02
CPC分类号： A61L31/145 , C09J9/02 , Y10S524/916 , Y10S525/936 , Y10S525/937
摘要： A composition providing electrically conductive adhesive hydrogels suitable for use as skin contact adhesives and, particularly, suitable for use as an electrical interface for disposable medical devices. The present hydrogels provide for reduced skin irritation and/or malodor properties, hydrate a subject's skin, readily wet around a subject's skin surface hair, and protect against burning of a subject upon or due to electrical stimulation through the hydrogel. These hydrogels generally include a monomer, a first initiator, a solubilizer, and a cross-linking agent. The present hydrogels also desirably include a buffer system to help prevent discoloration of the hydrogels and/or hydrolysis of the hydrogels as well as to improve shelf-life. Other additives such as conductivity enhancers, pharmaceuticals, humectants, plasticizers, skin health agents, etc. may be added to the present hydrogels either before or after curing.
摘要翻译：提供适合用作皮肤接触粘合剂并且特别适合用作一次性医疗装置的电接口的导电粘合剂水凝胶的组合物。本发明的水凝胶提供降低的皮肤刺激和/或恶臭特性，使受试者的皮肤水合，容易在受试者的皮肤表面毛发周围湿润，并防止受试者在通过水凝胶进行电刺激或由于电刺激引起的对象燃烧。这些水凝胶通常包含单体，第一引发剂，增溶剂和交联剂。本发明的水凝胶还理想地包括缓冲体系以帮助防止水凝胶的变色和/或水凝胶的水解以及改善保存期限。在固化之前或之后，可将其它添加剂如导电增强剂，药物，湿润剂，增塑剂，皮肤保健剂等添加到本发明的水凝胶中。

6. 发明申请

WO2003031483A1 DEGRADABLE THIOL-ENE POLYMERS 审中-公开
标题翻译：可降解的THIOL-ENE聚合物
公开(公告)号：WO2003031483A1
公开(公告)日：2003-04-17
申请号：PCT/US2002/032669
申请日：2002-10-10
申请人： THE REGENTS OF THE UNIVERSITY OF COLORADO
发明人： BOWMAN, Christopher , ANSETH, Kristi , HACIOGLU, Bilge , NUTTELMAN, Charlie
IPC分类号： C08F8/34
CPC分类号： C08L89/00 , A01N25/04 , A61K47/34 , A61L27/16 , A61L27/18 , A61L27/38 , A61L27/52 , A61L27/54 , A61L2300/62 , C05G3/0029 , C05G3/0076 , C08G75/045 , C08G81/00 , C08G81/027 , C08G2261/126 , C08J3/075 , C08J2329/04 , C08J2367/04 , C08J2371/02 , C08L71/02 , C08L81/02 , C08L2205/05 , Y10S524/916 , Y10S525/936 , C08L83/00 , C08L2666/22
摘要： A thiol-ene polymeric material is disclosed. The material is produced by the photopolymerization of reactants having thiol and olefin moieties. The material can incorporate encapsulated components, including cells. Additionally, the material can be derivatized by reacting the polymeric material with components such as proteins.
摘要翻译：公开了一种硫醇烯聚合物材料。该材料通过具有硫醇和烯烃部分的反应物的光聚合产生。该材料可以包含包封的组分，包括细胞。此外，可以通过使聚合物材料与诸如蛋白质的组分反应来衍生该材料。

7. 发明申请

WO1996003114A1 LOCK AND KEY MICELLES 审中-公开
标题翻译：锁和钥匙
公开(公告)号：WO1996003114A1
公开(公告)日：1996-02-08
申请号：PCT/US1995009188
申请日：1995-07-19
申请人： UNIVERSITY OF SOUTH FLORIDA
发明人： UNIVERSITY OF SOUTH FLORIDA , NEWKOME, George, R. , MOOREFIELD, Charles, N. , BAKER, Gregory, R.
IPC分类号： A61K09/107
CPC分类号： C07D213/75 , A61K47/6907 , A61K47/6949 , B82Y5/00 , C07C233/47 , C07D213/68 , C07D239/62 , C07D239/64 , C08G73/028 , C08G73/0627 , Y10S424/16 , Y10S525/903 , Y10S525/936 , Y10T428/2985 , Y10T428/2987
摘要： A lock unimolecular micelle includes at least one engineered acceptor specifically binding a ligand (or specifically a "key" unimolecular micelle) thereto. A key unimolecular micelle comprises a core molecule and a plurality of branches extending therefrom, at least one of the branches including a shank portion extending therefrom having a terminal moiety at an end thereof for binding to a complimentary acceptor of a lock unimolecular micelle. Together, the lock and key micelles form a unit, either irreversibly or reversibly bound wherein the lock micelles is a soluble receptor engineered to specifically bind to the specifically engineered key micelle.
摘要翻译：锁单分子胶束包括至少一个工程化受体，其特异性结合配体（或特别是“键”单分子胶束）。关键的单分子胶束包括芯分子和从其延伸的多个分支，至少一个分支包括从其延伸的柄部分，其端部具有末端部分，用于结合锁定单分子胶束的互补受体。锁和键胶束一起形成不可逆或可逆地结合的单元，其中锁定胶束是被工程化以特异性结合特异性工程化键键合物的可溶性受体。

8. 发明申请

WO2009150727A1 硬化性組成物审中-公开
标题翻译：可固化组合物
公开(公告)号：WO2009150727A1
公开(公告)日：2009-12-17
申请号：PCT/JP2008/060711
申请日：2008-06-11
申请人：電気化学工業株式会社 , 小林慶太 , 依田公彦 , 渡辺淳
发明人：小林慶太 , 依田公彦 , 渡辺淳
IPC分类号： C08F20/04 , C08F2/32 , C09J11/06 , C09J133/08
CPC分类号： C09J133/08 , C08F220/18 , C08F222/1006 , C08K5/14 , C08K9/10 , Y10S525/936
摘要：　被着体の間に間隙ができても、間隙の大きさが１００μｍ程度以下であれば十分に接着する速硬化性の硬化性組成物を提供する。　１種以上の有機過酸化物と、前記有機過酸化物と反応し、モノマーの重合を促進させる硬化促進剤と、単官能（メタ）アクリレートと、多官能性（メタ）アクリレートとを含有する硬化性組成物であって、前記有機過酸化物がマイクロカプセルに内包されていることを特徴とする硬化性組成物。好ましくは、前記単官能（メタ）アクリレートが、カルボキシル基を含有した（メタ）アクリレートと、脂環式炭化水素を含有した（メタ）アクリレートとを含有することを特徴とする前記の硬化性組成物。
摘要翻译：即使间隙大小为100μm以下，即使在被粘附体之间形成间隙也能令人满意地粘贴被粘体的快速固化固化性组合物。一种可固化组合物，其包含至少一种有机过氧化物，可与过氧化物反应以加速单体聚合的固化促进剂，单官能（甲基）丙烯酸酯和多官能（甲基）丙烯酸酯，其特征在于，所述过氧化物包封在微胶囊优选为上述固化性组合物，其特征在于，所述单官能（甲基）丙烯酸酯含有带有羧基的（甲基）丙烯酸酯和带有脂环族烃的（甲基）丙烯酸酯。

9. 发明申请

WO2005061017A2 ELECTRICALLY CONDUCTIVE ADHESIVE HYDROGELS WITH SOLUBILIZER 审中-公开
标题翻译：具有溶解性的电导电胶粘剂
公开(公告)号：WO2005061017A2
公开(公告)日：2005-07-07
申请号：PCT/US2004/029258
申请日：2004-09-08
申请人： KIMBERLY-CLARK WORLDWIDE, INC. , YAHIAOUI, Ali , KELLER, Caron , BORDERS, Richard, Arnold
发明人： YAHIAOUI, Ali , KELLER, Caron , BORDERS, Richard, Arnold
IPC分类号： A61L24/00
CPC分类号： A61L31/145 , C09J9/02 , Y10S524/916 , Y10S525/936 , Y10S525/937
摘要： A composition providing electrically conductive adhesive hydrogels suitable for use as skin contact adhesives and, particularly, suitable for use as an electrical interface for disposable medical devices. The present hydrogels provide for reduced skin irritation and/or malodor properties, hydrate a subject's skin, readily wet around a subject's skin surface hair, and protect against burning of a subject upon or due to electrical stimulation through the hydrogel. These hydrogels generally include a monomer, a first initiator, a solubilizer, and a cross-linking agent. The present hydrogels also desirably include a buffer system to help prevent discoloration of the hydrogels and/or hydrolysis of the hydrogels as well as to improve shelf-life. Other additives such as conductivity enhancers, pharmaceuticals, humectants, plasticizers, skin health agents, etc. may be added to the present hydrogels either before or after curing.
摘要翻译：提供适合用作皮肤接触粘合剂的导电粘合剂水凝胶的组合物，特别是适用于一次性医疗装置的电接口。本水凝胶提供减少的皮肤刺激和/或恶臭性质，使受试者的皮肤水合，容易地在受试者的皮肤表面毛发周围湿润，并且在通过水凝胶或通过水凝胶进行电刺激时防止受试者的燃烧。这些水凝胶通常包括单体，第一引发剂，增溶剂和交联剂。本发明的水凝胶还希望包括缓冲体系，以帮助防止水凝胶的变色和/或水凝胶的水解以及改善保质期。在固化前或之后，可将其它添加剂如导电促进剂，药物，保湿剂，增塑剂，皮肤保健剂等加入到本发明的水凝胶中。

10. 发明申请

WO9112293A3 HOT MELT ADHESIVE FORMULATION HEAT CURABLE BY EPOXY CROSSLINKING 审中-公开
标题翻译：环氧交联固化热熔胶粘剂配方热量
公开(公告)号：WO9112293A3
公开(公告)日：1991-10-03
申请号：PCT/US9100815
申请日：1991-02-06
申请人： EXXON CHEMICAL PATENTS INC
发明人： TSE MUN FU
IPC分类号： C09J123/08 , C09J123/26
CPC分类号： C09J123/26 , C08L2666/22 , C08L2666/34 , C09J123/08 , Y10S525/936
摘要： A heat curable hot melt adhesive system is disclosed. The system uses an epoxy-crosslinking ethylene polymer component, a tackifier compatible therewith and an epoxy crosslinking agent having an epoxide functionality of at least 2. The ethylene polymer component may be either an ethylene copolymer of an alpha , beta -ethylenically unsaturated carboxylic acid, or an ethylene copolymer of an ethylenically unsaturated alcohol used in combination with a dicarboxylic acid anhydride. The dicarboxylic acid anhydride and/or the epoxy can be encapsulated to inhibit premature crosslinking. The formulation is applied to a substrate surface as a hot melt at a moderate temperature, and subsequently cured by heating the adhesive composition to a higher curing temperature.
摘要翻译：公开了一种可热固化的热熔粘合剂体系。该体系使用环氧交联乙烯聚合物组分，与其相容的增粘剂和环氧官能度至少为2的环氧交联剂。乙烯聚合物组分可以是α，β-烯键式不饱和羧酸的乙烯共聚物，或与二羧酸酐组合使用的烯属不饱和醇的乙烯共聚物。二羧酸酐和/或环氧树脂可以被封装以抑制过早交联。该配制剂在中等温度下作为热熔体施加到基材表面，随后通过将粘合剂组合物加热到更高的固化温度而固化。

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