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1. 发明申请

WO2017132618A1 WEARABLE APPARATUS FOR DETECTING A TARGET SUBSTANCE IN A LIQUID 审中-公开
标题翻译：用于检测液体中的目标物质的可佩戴设备
公开(公告)号：WO2017132618A1
公开(公告)日：2017-08-03
申请号：PCT/US2017/015504
申请日：2017-01-27
申请人： UNDERCOVER COLORS, INC.
发明人： LETOURNEAU, Nicolas , KHALIFA, Aly , GORCZYNSKI, Michael , GOMES, Catherina , SMITH, Ronald , PALUSKIEWICZ, Sarah , GRAY, Stephen , CONFREY-MALONEY, Tyler
IPC分类号： G01N30/94 , C12Q1/70 , G01N33/14 , G01N33/48 , G01N33/50
CPC分类号： G01N33/94 , A61F13/00055 , A61F13/15 , A61F13/42 , A61F13/84 , A61F2013/422 , A61F2013/429 , A61F2013/8473 , G01N21/78 , G01N33/146 , G01N33/52 , G01N33/525 , G01N33/53 , G01N33/54366 , G01N33/558 , G01N2021/775 , G01N2021/7763 , G01N2021/7766
摘要： Described herein are a wearable apparatus and methods for detecting the presence of a targeted substance in a liquid. For example, the wearable apparatus can be a fingernail that detects illicit drugs in a beverage. The wearable apparatus comprises a detection layer comprising an indicator that is configured to display a signal upon the detection of an interaction with the targeted substance. In some examples, the wearable apparatus can include a lateral flow assay.
摘要翻译：本文描述用于检测液体中目标物质的存在的可佩戴设备和方法。例如，可穿戴设备可以是检测饮料中的非法药物的手指甲。可穿戴设备包括检测层，该检测层包括指示器，该指示器被配置为在检测到与目标物质的相互作用时显示信号。在一些示例中，可穿装置可以包括侧流测定。

2. 发明申请

WO2016186664A1 UNIVERSAL SOLVENT INDICATING SYSTEM 审中-公开
标题翻译：通用溶剂指示系统
公开(公告)号：WO2016186664A1
公开(公告)日：2016-11-24
申请号：PCT/US2015/031735
申请日：2015-05-20
申请人： BRADY WORLDWIDE, INC.
发明人： KASPER, Matthew , LABELLE, Michael , KROGMAN, Nicholas
IPC分类号： G01N31/22
CPC分类号： G01N33/525 , G01N31/22
摘要： A saturation indicator, such as a label, for indicating a state of saturation of a sorbent body by a sorbate includes a label body, an adhering element, and a universal indicating ink formulation disposed within the label body. The adhering element is configured to bond the label body to the sorbent body. The universal indicating ink formulation is disposed within the label body includes a resin and a dye dispersed in the resin in which the dye is configured to indicate the state of saturation of the sorbent body. The resin and the dye are soluble in a plurality of categories of sorbates selected from the group of categories of sorbates consisting of hydrophobic sorbates, hydrophilic sorbates, neutral sorbates, and amphiphilic sorbates. Alternative indicating structures are also described.
摘要翻译：用于通过山梨酸盐指示吸附剂体的饱和状态的饱和指示剂（例如标签）包括标签体，粘附元件和布置在标签体内的通用指示油墨配方。附着元件构造成将标签体粘合到吸附体上。通用指示油墨配方设置在标签体内，包括树脂和分散在树脂中的染料，其中染料被配置为指示吸附剂体的饱和状态。树脂和染料可溶于选自由疏水性山梨酸盐，亲水性山梨酸盐，中性山梨酸盐和两亲性山梨酸盐组成的一组类别的山梨酸盐的多种类型的山梨酸盐。还描述了替代指示结构。

3. 发明申请

WO2015005504A1 혈당측정용 바이오칩 및 그를 포함하는 스마트폰용 혈당측정기 审中-公开
标题翻译：用于测量血液葡萄糖水平的生物测定仪，以及含有同类物质的智力血糖仪
公开(公告)号：WO2015005504A1
公开(公告)日：2015-01-15
申请号：PCT/KR2013/006023
申请日：2013-07-08
申请人： 가천대학교 산학협력단 , 김상효
发明人： 김상효
IPC分类号： A61B5/145 , G01N33/48
CPC分类号： G01N21/78 , A61B5/14532 , A61B5/6898 , G01N21/8483 , G01N33/525 , G01N33/66 , G01N2021/7759
摘要： 혈당측정용 바이오칩 및 그를 포함하는 스마트폰용 혈당측정기가 제공된다. 본 발명의 일 측면에 따르면 일면에 혈당이 유입되는 혈당유입영역과 혈당유입영역과 연결된 반응영역이 형성되고, 반응영역에 오목부가 형성된 기판; 기판의 일면에 대향하여 혈당유입영역 상에 배치된 다공성 분리막; 및 기판의 반응영역 상에 분포하는, 실리카 나노입자와 반응시약;을 포함하는 혈당측정용 바이오칩이 제공된다. 이에 의하여, 휴대가 용이한 혈당측정용 바이오칩과 CMOS 이미지 센서를 이용하여 간편하게 혈당 측정을 가능하게 하고, 특히, 스마트폰에 장착된 CMOS 이미지 센서를 이용하여 간편하게 혈당을 측정할 수 있으며, 스마트폰에 설치된 혈당측정 어플리케이션에 의해 혈당을 정량적으로 측정하여 확인할 수 있다.
摘要翻译：提供了用于测量血糖水平的生物芯片和用于智能手机的血糖仪。根据本发明的一个方面，提供了一种用于测量血糖水平的生物芯片，包括：基底，其中形成血糖流过的血糖流入区域和连接到血糖流入区域的反应区域在反应区域形成凹部，面向所述基板的一个表面并且布置在所述血糖流入区上的多孔分离膜; 和二氧化硅纳米颗粒和分布在基材的反应区域上的反应试剂。因此，通过使用用于测量血糖水平的便携式生物芯片和CMOS图像传感器，可以方便地测量血糖水平，特别是可以通过使用提供给智能手机的CMOS图像传感器方便地测量血糖水平，并且血糖水平可以通过安装在智能手机上的血糖仪应用进行定量测量和检查。

4. 发明申请

WO2014012558A3 A DRY STICK DEVICE AND A METHOD FOR DETERMINING AN ANALYTE IN A SAMPLE 审中-公开
标题翻译：干燥装置和用于确定样品中分析物的方法
公开(公告)号：WO2014012558A3
公开(公告)日：2014-03-20
申请号：PCT/DK2013050245
申请日：2013-07-19
申请人： LATTEC I S
发明人： CLAUSEN KIM
IPC分类号： G01N33/52 , A01J5/007 , G01N33/53 , G01N33/543
CPC分类号： A01J5/0131 , A01K1/12 , A01K11/006 , G01N33/521 , G01N33/525
摘要： A novel and improved dry stick construction for the determination of an analyte in a sample is provided. The dry stick device comprises: (i) a solid support comprising a cavity, and (ii) at least one dry reagent capable of reacting with the analyte, a derivative of said analyte or an indicator compound for said analyte to provide a detectable signal when in a moistened state, wherein the cavity comprises the at least one dry reagent. The present invention also provides an automated or semi-automated system. Additionally the present invention provides an automated or semi-automated system for optimising the production performance of a milk producing animal herd.
摘要翻译：提供了用于测定样品中分析物的新颖和改进的干棒结构。干棒装置包括：（i）包含空腔的固体支持体，和（ii）能够与分析物反应的至少一种干燥试剂，所述分析物的衍生物或所述分析物的指示剂化合物，以便当处于润湿状态，其中所述空腔包含所述至少一种干试剂。本发明还提供一种自动或半自动化系统。另外，本发明提供了一种用于优化产奶动物群的生产性能的自动或半自动化系统。

5. 发明申请

WO2014035333A1 SOLID SUPPORTED ARTIFICIAL CELL MEMBRANE SYSTEM 审中-公开
标题翻译：固体支持的人造细胞膜系统
公开(公告)号：WO2014035333A1
公开(公告)日：2014-03-06
申请号：PCT/SG2012/000304
申请日：2012-08-29
申请人： AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH , CHENG, Jinting , NALLANI, Madhavan
发明人： CHENG, Jinting , NALLANI, Madhavan
IPC分类号： C07K17/08 , C08G77/452 , G01N33/52
CPC分类号： G01N33/525 , C07K17/08 , C08G77/452 , G01N33/545 , G01N33/566
摘要： The present invention relates to an artificial cell membrane system comprising at least one membrane protein carrier associated with at least one membrane protein, wherein the at least one membrane protein carrier comprises or consists of a polymeric vesicle or a polymeric planar structure, and a solid support freely suspended in a fluid medium, wherein the at least one membrane protein carrier is attached to a surface of the solid support. A method of forming the artificial cell membrane system, and use of the artificial cell membrane system as a reagent are also provided.
摘要翻译：本发明涉及包含与至少一种膜蛋白相关的至少一种膜蛋白载体的人造细胞膜系统，其中所述至少一个膜蛋白载体包含聚合物囊泡或聚合物平面结构或由聚合物平面结构构成，自由地悬浮在流体介质中，其中所述至少一个膜蛋白载体连接到固体支持物的表面。还提供了形成人造细胞膜系统的方法以及人造细胞膜系统作为试剂的用途。

6. 发明申请

WO2014006638A1 DEVICE AND METHOD FOR BLOOD HEMOGLOBIN MEASUREMENT WITHOUT CARBOXYHEMOGLOBIN INTERFERENCE 审中-公开
标题翻译：用于血红蛋白测定的血清白蛋白干扰的装置和方法
公开(公告)号：WO2014006638A1
公开(公告)日：2014-01-09
申请号：PCT/IN2013/000406
申请日：2013-07-02
申请人： SRIVASTAVA, Ambar
发明人： SRIVASTAVA, Ambar
IPC分类号： G01N21/84 , G01N33/72
CPC分类号： G01N21/31 , G01N21/8483 , G01N33/525 , G01N33/721 , G01N2201/061 , G01N2201/068
摘要： The present invention provides a device and a method for blood haemoglobin measurement without carboxyhaemoglobin interference. In the present device and method, oxyhemoglobin, deoxyhemoglobin and methemoglobin are converted into a methemoglobin derivative, i.e. Imidazole-methemoglobin. Imidazole-methemoglobin and carboxyhemoglobin in the matrix (2) are collectively quantified by the reflectance spectroscopy (spectrometer 6, 7 and 8) of the matrix at 525 nm, the isobestic point between Imidazole- methemoglobin complex and carboxyhemoglobin molecule.
摘要翻译：本发明提供一种没有羧基血红蛋白干扰的血红蛋白测定装置和方法。在本装置和方法中，将氧合血红蛋白，脱氧血红蛋白和高铁血红蛋白转化为高铁血红蛋白衍生物，即咪唑高铁血红蛋白。基质（2）中的咪唑高铁血红蛋白和碳氧血红蛋白通过基质在525nm处的反射光谱（光谱仪6,7和8），咪唑 - 高铁血红蛋白复合物和碳氧血红蛋白分子之间的异质点共同量化。

7. 发明申请

WO2012027219A1 PRE-ASSEMBLED AND PRE-WET MULTILAYER SUBSTRATE FOR WESTERN BLOTTING 审中-公开
标题翻译：预先组装和预浸多层底物用于西式喷涂
公开(公告)号：WO2012027219A1
公开(公告)日：2012-03-01
申请号：PCT/US2011/048402
申请日：2011-08-19
申请人： ADVANCED BIOSCIENCE TECHNOLOGIES, LLC , PLUSKAL, Malcolm, G.
发明人： PLUSKAL, Malcolm, G.
IPC分类号： G01N33/53
CPC分类号： G01N33/525
摘要： The invention pertains to packaged, pre-assembled and pre-wet multilayer substrates for analyte transfer, particularly for use with Western Blotting techniques. The multilayer substrate comprises components of traditional Western Blotting but it is pre-assembled into a laminated unit that stays together after assembly and storage. The multilayer substrate comprises a vapor barrier layer contiguously disposed on the outermost layer of the substrate; and a layer comprising blotting material that is pre-wet, the multilayer substrate being assembled in a laminated unit.
摘要翻译：本发明涉及用于分析物转移的包装，预组装和预湿多层底物，特别是用于Western Blotting技术。多层基材包括传统的Western Blotting的组分，但它被预组装成组装和储存后保持在一起的层压单元。多层基板包括连续地设置在基板的最外层上的蒸气阻挡层; 以及包括预浸渍的印迹材料的层，多层基板被组装成层压单元。

8. 发明申请

WO2010105850A8 TEST ELEMENT FOR DETERMINING A BODY FLUID AND MEASUREMENT METHOD 审中-公开
标题翻译：测试元件用于测定体液和方法测量
公开(公告)号：WO2010105850A8
公开(公告)日：2011-01-27
申请号：PCT/EP2010001752
申请日：2010-03-19
申请人： ROCHE DIAGNOSTICS GMBH , HOFFMANN LA ROCHE , HAAR HANS-PETER , HORN CARINA
发明人： HAAR HANS-PETER , HORN CARINA
IPC分类号： C12Q1/54 , G01N21/63 , G01N33/52 , G01N33/66
CPC分类号： G01N33/66 , G01N21/6408 , G01N21/77 , G01N21/78 , G01N21/8483 , G01N33/525 , G01N2021/7786 , Y10T436/144444
摘要： The invention relates to a test element for determining a body fluid, in particular for determining the blood glucose level, comprising a detection region which is charged with a reagent sensitive to the body fluid. According to the invention, a functional element is arranged in and/or adjacent to the detection region for detecting at least one status parameter for the detection region, wherein said functional element can be evaluated by means of a status measurement. The invention further relates to a method for measuring the test element.
摘要翻译：本发明涉及一种测试元件，用于确定体液，尤其是用于确定血糖，与加载有敏感的体液试剂的检测区域，其中，在用于通过状态测量来检测所述检测区域的至少一个状态参数的检测区域和/或相邻的一个可分析的功能元件被布置。此外，本发明涉及一种用于测量测试元件的方法。

9. 发明申请

WO2011003586A1 CHIP FOR DETERMINATION OF MOLECULAR STRUCTURES AND FUNCTIONS 审中-公开
标题翻译：用于确定分子结构和功能的芯片
公开(公告)号：WO2011003586A1
公开(公告)日：2011-01-13
申请号：PCT/EP2010/004095
申请日：2010-07-07
申请人： LEISTER PROCESS TECHNOLOGIES , DI BERARDINO, Marco , VOEROES, Janos , SUGIHARA, Kaori , ZAMBELLI, Tomaso
发明人： DI BERARDINO, Marco , VOEROES, Janos , SUGIHARA, Kaori , ZAMBELLI, Tomaso
IPC分类号： G01N33/50 , G01N33/52 , B01L3/00 , G01N27/00 , G01N33/487
CPC分类号： G01N33/5005 , G01N33/48721 , G01N33/5097 , G01N33/525
摘要： The present invention describes a chip for measuring transport properties of cell membranes or lipid bilayers comprising at least a substrate having a topside and a backside and plurality of nano- or micro-pores and a cell membrane covering the plurality of pores being accessible from both sides of the cell membrane for measurement. A material layer at least in the region of the pores to support the cell membrane at the pores but not hindering the transport through the cell membrane and the pores is arranged on the substrate, either on the topside or on the backside. Electrodes are attached to the substrate for electrochemically measurement of the differences in the current through the membrane and the pores for monitoring transport processes. Both sides of the membrane are accessible by this structure.
摘要翻译：本发明描述了一种用于测量细胞膜或脂质双层的输送性能的芯片，其包括至少具有顶侧和背面以及多个纳米或微孔的基底和覆盖多个孔的细胞膜，两个孔可从两侧接近的细胞膜用于测量。至少在孔的区域中的材料层，以在孔处支撑细胞膜但不阻碍细胞膜的传输，并且孔在顶侧或背面上布置在基底上。电极连接到基底上，用于电化学测量通过膜和孔的电流差异，用于监测运输过程。膜的两侧可通过该结构进入。

10. 发明申请

WO2010105850A3 TEST ELEMENT FOR DETERMINING A BODY FLUID AND MEASUREMENT METHOD 审中-公开
标题翻译：测定身体流体的测试元件和测量方法
公开(公告)号：WO2010105850A3
公开(公告)日：2010-11-25
申请号：PCT/EP2010001752
申请日：2010-03-19
申请人： ROCHE DIAGNOSTICS GMBH , HOFFMANN LA ROCHE , HAAR HANS-PETER , HORN CARINA
发明人： HAAR HANS-PETER , HORN CARINA
IPC分类号： C12Q1/54 , G01N21/63 , G01N33/52 , G01N33/66
CPC分类号： G01N33/66 , G01N21/6408 , G01N21/77 , G01N21/78 , G01N21/8483 , G01N33/525 , G01N2021/7786 , Y10T436/144444
摘要： The invention relates to a test element for determining a body fluid, in particular for determining the blood glucose level, comprising a detection region which is charged with a reagent sensitive to the body fluid. According to the invention, a functional element is arranged in and/or adjacent to the detection region for detecting at least one status parameter for the detection region, wherein said functional element can be evaluated by means of a status measurement. The invention further relates to a method for measuring the test element.
摘要翻译：本发明涉及一种测试元件，用于确定体液，尤其是用于确定血糖，与加载有敏感的体液试剂的检测区域，其中，在用于通过状态测量来检测所述检测区域的至少一个状态参数的检测区域和/或相邻的一个可评估的功能元件被布置。此外，本发明涉及用于测量测试元件的方法。

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