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    • 1. 发明申请
    • PARTICLE CHARACTERISATION INSTRUMENT
    • 粒子表征仪器
    • WO2018069024A1
    • 2018-04-19
    • PCT/EP2017/074094
    • 2017-09-22
    • MALVERN INSTRUMENTS LIMITED
    • SCULLION, RichardCORBETT, Jason
    • G01N15/02G01N15/14G01N21/51G01N21/49G01N21/47
    • G01N15/0211G01N15/1434G01N15/1456G01N21/49G01N2015/0222G01N2015/1454G01N2021/4707G01N2021/4709G01N2201/063G01N2201/0635
    • A particle characterisation instrument (200), comprising a light source (201), a sample cell (202), an optical element (204) between the light source (201) and sample cell (202) and a detector (203). The optical element (204) is configured to modify light from the light source (201) to create a modified beam (207), the modified beam (207): a) interfering with itself to create an effective beam (208) in the sample cell (202) along an illumination axis (206) and b) diverging in the far field to produce a dark region (209) along the illumination axis (206) that is substantially not illuminated at a distance from the sample cell (202). The detector (203) is at the distance from the sample cell (202), and is configured to detect light scattered from the effective beam (208) by a sample in the sample cell (202), the detector (203) positioned to detect forward or back scattered light along a scattering axis (306) that is at an angle of 0° to 10° from the illumination axis (206).
    • (201),样品池(202),在光源(201)和样品池(202)之间的光学元件(204)的粒子表征仪器(200) 和检测器(203)。 所述光学元件(204)被配置为修改来自所述光源(201)的光以创建修改后的光束(207),所述修改后的光束(207):a)自行干涉以在所述样本中创建有效光束 沿着照明轴线(206)照射单元(202),以及b)在远场内发散以产生沿着照明轴线(206)的暗区域(209),其在距样本单元(202)一定距离处基本上未被照射。 检测器(203)与样本单元(202)相距一定距离,并且被配置为检测由样本单元(202)中的样本从有效射束(208)散射的光,检测器(203)被定位成检测 沿着散射轴(306)的前向散射光或后向散射光,散射轴(306)处于0°的角度; 到10℃ 来自照明轴(206)。
    • 2. 发明申请
    • ORGANISM IDENTIFICATION
    • 生物识别
    • WO2016054408A3
    • 2017-05-26
    • PCT/US2015053553
    • 2015-10-01
    • PURDUE RESEARCH FOUNDATION
    • BAE EUIWONBHUNIA ARUN KHIRLEMAN EDWIN DANIELKIM HUISUNGRAJWA BARTLOMIEJ PROBINSON JOSEPH PAULPATSEKIN VALERY
    • C12M1/34C12Q1/04G01N23/04
    • G01N21/47G01N21/255G01N21/51G01N2021/4707G01N2021/4709
    • A system for the identification of micro-organisms includes an irradiation unit adapted to sequentially provide coherent electromagnetic radiation of one or more wavelengths along a common optical path. A holder is adapted to retain a substrate having a surface adapted for growth of a micro-organism colony. A beamsplitter is adapted to direct the coherent electromagnetic radiation from the common optical path towards the retained substrate. An imager is arranged opposite the beamsplitter from the retained substrate and is adapted to obtain images of backward-scattered light patterns from the micro-organism colony irradiated by the respective wavelengths of the directed coherent electromagnetic radiation. Some examples provide radiation of multiple wavelengths and include an imager arranged optically downstream of the retained substrate to obtain images of forward-scattered light patterns from the micro¬ organism colony irradiated by the wavelengths of radiation. Organism identification methods are also described.
    • 用于识别微生物的系统包括照射单元,其适于沿公共光路顺序地提供一个或多个波长的相干电磁辐射。 保持器适于保持具有适于微生物菌落生长的表面的基底。 分束器适用于将来自公共光路的相干电磁辐射导向保留的衬底。 成像器与分束器相对地被布置为与被保持的基板相对,并且适于从被定向相干电磁辐射的相应波长照射的微生物集落获得后向散射光图案的图像。 一些示例提供多个波长的辐射,并且包括光学地布置在保留的基底下游的成像器,以从由辐射波长辐射的微生物群体获得前向散射光图案的图像。 还描述了生物体识别方法。
    • 4. 发明申请
    • MEANS FOR DETERMINING DEPTH-RESOLVED PHYSICAL AND/OR OPTICAL PROPERTIES OF SCATTERING MEDIA
    • 用于确定散射介质深度分辨的物理和/或光学性质的手段
    • WO2012149175A9
    • 2016-06-09
    • PCT/US2012035234
    • 2012-04-26
    • GEN HOSPITAL CORPVERMEER KOENRAAD ADE BOER JOHANNES F
    • VERMEER KOENRAAD ADE BOER JOHANNES F
    • A61B5/00A61B6/03G01N21/47
    • A61B3/102A61B8/10G01B9/02083G01B9/02091G01N21/47G01N21/4795G01N2021/4709
    • In depth-resolved imaging of scattering media, incident light interacts with tissue in a complex way before the signal reaches the detector. Light interacts with media between the light source and a specific depth, then scatters at that depth and the back scattered light again interacts with media, on its way to the detector. The resulting depth-resolved signal therefore likely does not directly represent a physical or optical property of the media at those depths. According to an exemplary embodiment of the present disclosure, systems, methods and computer-accessible medium can be provided to determine physical or optical properties based on such a depth-resolved signal. For example, almost all the light can interact with the media, and that the energy of the incident light at a certain depth is likely therefore related to the integral of the scattered light from all deeper locations. Based on the detected signals, the properties of the media can be estimated in an iterative way. The exemplary system, method and computer-accessible medium can be used together with, e.g., retinal optical coherence tomography data, facilitating the calculation of depth-resolved attenuation coefficients. It is possible to, e.g., transform data resulting from complex interactions of light and media at a range of depths into data representing a decoupled physical or optical property of the tissue at a range of depths.
    • 在散射介质的深度分辨成像中,入射光在信号到达检测器之前以复杂的方式与组织相互作用。 光与光源和特定深度之间的介质相互作用,然后在该深度处散射,并且后向散射光再次与介质在到达检测器的途中相互作用。 因此,所得到的深度分辨信号可能不直接表示在这些深度处的介质的物理或光学属性。 根据本公开的示例性实施例,可以提供系统,方法和计算机可访问介质,以基于这样的深度分辨信号来确定物理或光学属性。 例如,几乎所有的光都可以与介质相互作用,并且入射光在一定深度的能量很可能与来自所有较深位置的散射光的积分有关。 基于检测到的信号,可以以迭代的方式估计介质的性质。 示例性系统,方法和计算机可访问介质可以与例如视网膜光学相干断层摄影数据一起使用,便于深度分辨衰减系数的计算。 例如,可以将在深度范围内的光和介质的复杂相互作用产生的数据变换为表示在深度范围内的组织的去耦物理或光学属性的数据。
    • 9. 发明申请
    • AIRBORNE CLOUD AND PARTICLE DETECTOR FOR USE WITH A WEATHER BALLOON
    • AIRBORNE云和颗粒探测器与天气气球一起使用
    • WO2015067929A1
    • 2015-05-14
    • PCT/GB2014/053268
    • 2014-11-04
    • THE UNIVERSITY OF READING
    • HARRISON, Richard GilesNICOLL, Kerianne
    • G01N21/53
    • G01N21/538G01N2021/4709
    • A radiosonde system (2) is disclosed together with a ground station (12). The radiosonde system (2) comprises a radiosonde (4) suspended below a balloon (6) with a rope (8). The radiosonde (4) includes an optical cloud detector (30) with a plurality of LEDs (16, 18, 20, 22) and a photodiode (24). Light is emitted from the LEDs (16, 18, 20, 22) and back-scattered from particles in a cloud so that it is received by the photodiode (24). Each LED (16, 18, 20, 22) has a different optical characteristic, and differences in the back-scattered light from the respective LEDs is determined to be indicative of at least one property of the cloud particles.
    • 无线电探空仪系统(2)与地面站(12)一起公开。 无线电探空仪系统(2)包括悬挂在具有绳索(8)的气球(6)下方的无线电探空仪(4)。 无线电探空仪(4)包括具有多个LED(16,18,20,22)和光电二极管(24)的光云探测器(30)。 光从LED(16,18,20,22)发射并从云中的颗粒反向散射,使得其被光电二极管(24)接收。 每个LED(16,18,20,22)具有不同的光学特性,并且来自各个LED的反向散射光的差异被确定为指示云颗粒的至少一个性质。
    • 10. 发明申请
    • DISPOSITIF, SYSTEME ET PROCEDE DE DETECTION PERMETTANT DE DETECTER LA PRESENCE D'UN MICRO-ORGANISME DANS UN ECHANTILLON A L'INTERIEUR D'UN CONTENANT
    • 检测装置,系统和方法可以检测微量元素在样品中或在容器内的存在
    • WO2014198718A1
    • 2014-12-18
    • PCT/EP2014/062024
    • 2014-06-10
    • BIOMÉRIEUX
    • COLIN, BrunoDE LA FOATA, CorinneDACHAUD, JacquesMADE, Fabienne
    • G01N21/51G01N21/64G01N21/01G01N21/47
    • C12M41/36C12M41/06C12Q1/04G01N21/51G01N21/6428G01N21/645G01N2021/0112G01N2021/4709G01N2021/4769G01N2201/0221G01N2201/062G01N2201/12
    • 1. Dispositif de détection (10) de la présence d'au moins un micro-organisme dans le contenu (101, 201) d'un contenant (100, 200) comprenant une paroi avec une zone translucide, ledit dispositif de détection (10) comprenant: a) au moins une source lumineuse (11), telle qu'une diode électroluminescente (LED), susceptible d'illuminer le contenu (101, 201) du contenant (100, 200) en émettant un faisceau lumineux d'excitation au travers de la zone translucide du contenant (100, 200); b) au moins un moyen de détection (12,13, 14,15), tel qu'une photodiode, pour détecter au moins un faisceau lumineux de réaction émis en réponse à l'illumination du contenu (101, 201) du contenant (100, 200); ladite au moins une source lumineuse (11) et ledit au moins un moyen de détection (12, 13, 14, 15) étant pourvus d'au moins un moyen de connexion (105, 205) entièrement localisé à l'extérieur du contenant (100, 200) pour connecter ladite au moins une source lumineuse (11) et ledit au moins un moyen de détection (12, 13, 14, 15) à la paroi du contenant (100, 200), au niveau de la zone translucide, ledit moyen de connexion (105, 205) permettant d'adapter la position du dispositif de détection (10) sur la paroi du contenant (100, 200), ledit au moins un moyen de détection (12, 13, 14, 15) étant positionné selon un angle de valeur déterminée par rapport à la direction du faisceau lumineux d'excitation pour détecter le faisceau lumineux de réaction.
    • 1.本发明涉及一种用于检测包含具有半透明区域的壁的容器(100,200)的内容物(101,201)中至少一种微生物的存在的装置(10),所述检测装置 10)包括:a)至少一个能够通过发射激发光束照射容器(100,200)的内容物(101,201)的发光二极管(LED)的光源(11) 通过容器(100,200)的半透明区域; b)至少一个检测装置(12,13,14,15),例如光电二极管,用于检测响应于容器(100,201)的内容物(101,201)的照射而发射的至少一个反应光束, 200); 所述至少一个光源(11)和所述至少一个检测装置(12,13,14,15)设置有至少一个位于容器(100,200)外部的连接装置(105,205),以连接 所述至少一个光源(11)和所述至少一个检测装置(12,13,14,15)在所述透光区域处于所述容器(100,200)的所述壁上,所述连接装置(105,205) 使得可以将检测装置(10)的位置适应在容器(100,200)的壁上,所述至少一个检测装置(12,13,14,15)以与预定值成一定角度定位 相对于激发光束的方向来检测反应光束。