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1. 发明申请

WO2017001357A1 EXTRACORPOREAL BLOOD TREATMENT APPARATUS FOR SINGLE-NEEDLE TREATMENTS 审中-公开
标题翻译：用于单针治疗的外用血液治疗装置
公开(公告)号：WO2017001357A1
公开(公告)日：2017-01-05
申请号：PCT/EP2016/064912
申请日：2016-06-28
申请人： GAMBRO LUNDIA AB
发明人： COURT, Thierry , ERICSON, Björn , NILSSON, Roger , HÅKANSSON, AnnMargret
IPC分类号： A61M1/30 , A61M1/36
CPC分类号： A61M1/303 , A61M1/306 , A61M1/3627 , A61M2205/3334 , A61M2205/3368 , A61M2205/3382 , A61M2205/3386
摘要： An extracorporeal blood circuit (11) cooperating with a single blood pump (30) and having at least one blood chamber (18; 80) in the blood return line but no blood chamber in the blood withdrawal line; and an extracorporeal blood treatment apparatus (1) configured for single needle treatments comprising the extracorporeal blood circuit (11) wherein the apparatus has a control unit (100) configured to control a pneumatic circuit (40) and the blood pump (30) such as to keep pressure in the blood circuit under control during both an arterial and a venous phase of the single needle cycles. A method for controlling the apparatus is also disclosed.
摘要翻译：一个体外血液回路（11）与单个血液泵（30）配合并且在血液返回管路中具有至少一个血液腔室（18; 80），但在血液输送管线中没有血液腔室; 以及构造成用于单针治疗的体外血液处理装置（1），其包括体外血液回路（11），其中所述装置具有被配置为控制气动回路（40）和所述血泵（30）的控制单元（100）在单次针刺循环的动脉期和静脉期期间在血液回路中保持压力。还公开了一种用于控制该装置的方法。

2. 发明申请

WO2012004103A1 AN AMBULATORY ULTRAFILTRATION DEVICE, RELATED METHODS AND A COMPUTER PROGRAM PRODUCT 审中-公开
标题翻译：一种超声波超声装置，相关方法和计算机程序产品
公开(公告)号：WO2012004103A1
公开(公告)日：2012-01-12
申请号：PCT/EP2011/060019
申请日：2011-06-16
申请人： GAMBRO LUNDIA AB , JÖNSSON, Lennart , STERNBY, Jan , WIESLANDER, Anders
发明人： JÖNSSON, Lennart , STERNBY, Jan , WIESLANDER, Anders
IPC分类号： A61M1/30
CPC分类号： A61M1/30 , A61M1/302 , A61M1/303 , A61M1/3427 , A61M1/3604 , A61M1/365 , A61M1/3672 , A61M2209/088
摘要： An ultrafiltration device is designed to be used for ambulatory SCUF or other types of continuous or intermittent ultrafiltration, typically while being worn or otherwise carried by the subject (S) that is being treated. The ambulatory ultrafiltration device comprises a blood filter (4) that has a blood side (6) for fluid communication with the vascular system of the subject (S), an ultrafiltrate side (7), and a semipermeable membrane (8) disposed between the blood side (6) and the ultrafiltrate side (7). The ambulatory ultrafiltration also comprises a buffer vessel (3) in fluid communication with the blood side (6) of the blood filter (4), and a blood pump (9). The blood pump (9) is controlled to alternate between a withdrawal phase and a return phase. In the withdrawal phase, blood is withdrawn on a blood path from the subject (S) via the blood filter (4) to the buffer vessel (3). In the return phase, blood is returned from the buffer vessel (3) to the subject (S) on the blood path. The blood filter (4) is arranged to remove ultrafiltrate from the blood during at least one of the withdrawal and return phases. The use of a single blood path for withdrawal of blood and return of treated blood makes the device suitable for ambulatory ultrafiltration.
摘要翻译：超滤装置设计用于移动SCUF或其他类型的连续或间歇超滤，通常在正在治疗的受试者（S）穿着或以其他方式携带时。动态超滤装置包括血液过滤器（4），其具有用于与受试者（S）的血管系统流体连通的血液侧（6），超滤液侧（7）和设置在所述受试者的血液系统之间的半透膜（8）血液侧（6）和超滤液侧（7）。动态超滤还包括与血液过滤器（4）的血液侧（6）流体连通的缓冲容器（3）和血液泵（9）。血泵（9）被控制为在抽出阶段和返回阶段之间交替。在取出阶段，血液在血液路径上从被检体（S）经由血液过滤器（4）抽出到缓冲容器（3）。在返回阶段，将血液从缓冲容器（3）返回到血液路径上的受试者（S）。血液过滤器（4）布置成在至少一个抽出和返回阶段期间从血液中除去超滤液。使用单个血液路径来取出血液并返回处理过的血液，使得该装置适合于动态超滤。

3. 发明申请

WO2008148505A2 DEVICE AND METHOD FOR BLOOD TREATMENT IN SINGLE-NEEDLE OPERATING MODE 审中-公开
标题翻译：装置及方法EINNADELBETRIEB血液处理
公开(公告)号：WO2008148505A2
公开(公告)日：2008-12-11
申请号：PCT/EP2008004353
申请日：2008-05-31
申请人： FRESENIUS MEDICAL CARE DE GMBH , GUENTHER GOETZ , HERRENBAUER MICHAEL , LAUER MARTIN , MUELLER RALF
发明人： GUENTHER GOETZ , HERRENBAUER MICHAEL , LAUER MARTIN , MUELLER RALF
IPC分类号： A61M1/34 , A61M1/16
CPC分类号： A61M1/306 , A61M1/30 , A61M1/302 , A61M1/303 , A61M1/307 , A61M1/308 , A61M2205/07 , A61M2205/3337 , A61M2205/3368
摘要： The invention relates to a device and a method for blood treatment in a single-needle operating mode. The blood treatment device has an extracorporeal blood circuit (1) comprising a blood supply line (8) leading to the inlet of a blood treatment unit (2) and a blood return line (8) leading away from the outlet of the blood treatment unit. Blood collecting means, for example a blood collecting container, are provided in the blood return line, said means being connected to means (18) for storing gas, for example an air reservoir, by a flow line. The flow connection comprises two line branches, one branch being used to transfer gas from the air reservoir into the blood collecting container and the other branch being used to transfer gas from the blood collecting container into the air reservoir. The connection branch for transferring gas from the air store into the blood collecting container contains means (20) for compressing air, for example a compressor. The device according to the invention is operated in such a way that the filling level of the means for collecting blood can be determined as precisely as possible.
摘要翻译：本发明涉及一种装置和用于血液处理对于单针操作的方法。血液处理设备包括具有到血液处理单元的入口的体外血液回路（1）（2），从而导致血液供应管线（8）和从所述血液处理单元血液返回管线的出口的出射（9）。在血液返回线装置（11），用于收集血液被布置，例如，用于存储气体，例如空气储罐设置有装置（18）一种血液采集容器处于流体连通。流连接包括两个线路分支，所述气体从所述空气存储容器转移到血液采集容器，和用于从血液采集容器的气体转移Fuhren另一个导管分支在空气储存器的线分支。用于从血液采集容器中的空气蓄压器的气体传送Fuhren连接分支包含用于压缩的空气，例如压缩机装置（20）。本发明的装置被操作，使得用于收集血液的装置的水平可以精确地确定成为可能。

4. 发明申请

WO2007041716A1 METHOD AND APPARATUS FOR LEUKOREDUCTION OF RED BLOOD CELLS 审中-公开
标题翻译：红血细胞淋巴细胞的方法和装置
公开(公告)号：WO2007041716A1
公开(公告)日：2007-04-12
申请号：PCT/US2006/039153
申请日：2006-10-05
申请人： GAMBRO, INC. , GIBBS, Bruce
发明人： GIBBS, Bruce
IPC分类号： A61M1/36 , A61M1/38
CPC分类号： A61M1/3696 , A61M1/0218 , A61M1/0231 , A61M1/30 , A61M1/303 , A61M1/308 , A61M1/3496 , A61M1/3633 , A61M1/3693 , A61M1/38 , A61M2205/123
摘要： This invention relates to a method for the continuous separation of red blood cells from whole blood which includes the steps of removing the whole blood from a donor, continuously separating the whole blood into blood component layers within a separation vessel including at least a plasma layer, a buffy coat layer and a red blood cell layer, removing the plasma layer from the separation vessel, removing the buffy coat layer from the separation vessel, and removing red blood cells from the red blood cell layer which partially overlaps with the buffy coat layer to create a mononuclear cell (MNC)-reduced red blood cell layer in the separation vessel.
摘要翻译：本发明涉及一种从全血中连续分离红细胞的方法，包括从供体中除去全血的步骤，将全血连续分离成至少包含等离子体层的分离容器内的血液成分层，血沉棕黄层和红细胞层，从分离容器中除去血浆层，从分离容器中除去血沉棕黄层，并从与血沉棕黄层部分重叠的红细胞层中除去红细胞，在分离容器中产生单核细胞（MNC） - 减少红细胞层。

5. 发明申请

WO2005028002A1 BLOOD OXYGENATION SYSTEM WITH SINGLE LUMEN CATHETER 审中-公开
标题翻译：血液氧化系统与单个灯管
公开(公告)号：WO2005028002A1
公开(公告)日：2005-03-31
申请号：PCT/IL2004/000880
申请日：2004-09-22
申请人： HAIMOVICH, Dudu , ROTTENBERG, Dan
发明人： HAIMOVICH, Dudu , ROTTENBERG, Dan
IPC分类号： A61M1/16
CPC分类号： A61M1/1698 , A61M1/0072 , A61M1/1625 , A61M1/30 , A61M1/302 , A61M1/303 , A61M1/304 , A61M1/307
摘要： A system for blood oxygenation. The system comprises a blood oxygenator in which a blood compartment and a gas compartment are separated by a gas permeable barrier so as to allow exchange of carbon dioxide in blood in the blood compartment with oxygen in the gas compartment. The proximal end of a catheter is connected to the blood oxygenator, while the distal end of the catheter is inserted into a blood vessel. A pump alternates between causing blood to flow in the catheter lumen from the blood vessel to the oxygenator and causing blood to flow in the catheter lumen from the oxygenator to the blood vessel.
摘要翻译：血氧合系统。该系统包括血液充氧器，其中血液隔室和气体隔室由气体可渗透屏障分开，以便允许血液隔室中的血液中的二氧化碳与气体隔室中的氧气交换。导管的近端与血液充氧器相连，同时将导管的远端插入血管。泵在导管血管中从血管流到氧合器并使血液在导管腔中从充氧器流到血管的位置交替。

6. 发明申请

WO03033066A3 BLOOD PROCESSING SYSTEMS AND METHODS THAT EMPLOY AN IN-LINE LEUKOFILTER MOUNTED IN A RESTRAINING FIXTURE 审中-公开
标题翻译：血液加工系统和方法，在一个限制条件下安装一个在线白炽灯
公开(公告)号：WO03033066A3
公开(公告)日：2003-07-31
申请号：PCT/US0231316
申请日：2002-10-02
申请人： BAXTER INT
发明人： VANDLIK MARK R , KAST MICHAEL J , SMITH KELLY B
IPC分类号： A61M1/02 , A61M1/10 , A61M1/30 , A61M1/36 , A61M37/00 , B01D33/15 , C02F1/00
CPC分类号： A61M1/3696 , A61M1/0209 , A61M1/0218 , A61M1/1006 , A61M1/1037 , A61M1/1062 , A61M1/30 , A61M1/302 , A61M1/303 , A61M1/308 , A61M1/3633 , A61M1/3636 , A61M1/3693 , A61M2205/12 , A61M2205/128 , A61M2205/331 , A61M2205/3393
摘要： Systems and methods separate blood cells from whole blood and pump the separated blood cells through an in-line leukofilter to a blood cell storage container. The leukofilter comprises a filtration medium enclosed within a flexible housing. The systems and methods include a fixture to restrain expansion of the flexible filter housing during operation of the pump. The fixture includes a bracket to enable its releasable attachment to the blood processing device employed to carry out the separation process.
摘要翻译：系统和方法将血液细胞与全血分离，并将分离的血液细胞通过直列式白细胞滤器泵送至血细胞储存容器。白细胞滤器包括封装在柔性壳体内的过滤介质。该系统和方法包括在泵的操作期间抑制柔性过滤器壳体的膨胀的夹具。固定装置包括支架，以使其能够可释放地附接到用于执行分离过程的血液处理装置。

7. 发明申请

WO2002070035A2 MULTI-PURPOSE, AUTOMATED BLOOD AND FLUID PROCESSING SYSTEMS AND METHODS 审中-公开
标题翻译：多目的，自动血液和流体加工系统及方法
公开(公告)号：WO2002070035A2
公开(公告)日：2002-09-12
申请号：PCT/US2002/005244
申请日：2002-02-13
申请人： BAXTER INTERNATIONAL INC.
发明人： MIN, Kyungyoon , BROWN, Richard, I. , VISHNOI, Rohit , ARMER, Alan , WESTBERG, Tom
IPC分类号： A61M
CPC分类号： A61M1/3687 , A61M1/262 , A61M1/30 , A61M1/302 , A61M1/303 , A61M1/308 , A61M1/342 , A61M1/3441 , A61M1/3672 , A61M1/3675 , A61M1/3679 , A61M1/3692 , A61M1/3693 , A61M1/3696 , A61M2202/0427 , A61M2205/12
摘要： Automated systems and method for processing blood and other fluids are disclosed. The systems and methods utilize a disposable fluid circuit mounted on a re-usable hardware component or module. The system withdraws blood from a donor or patient, separates the blood into two or more components and further processes or treats the separated component.
摘要翻译：公开了用于处理血液和其它流体的自动化系统和方法。该系统和方法利用一次性流体回路图。该系统安装在可重复使用的硬件部件或模块12上。系统从供体或患者100抽出血液，将血液分离成两个或更多个部件，并进一步处理或处理分离的部件。

8. 发明申请

WO2002066110A1 BLOOD COLLECTION SYSTEMS AND METHODS THAT DERIVE ESTIMATED EFFECTS UPON THE DONOR'S BLOOD VOLUME AND HEMATOCRIT 审中-公开
标题翻译：血液收集系统和方法，对捐助者的血液和血液进行估计效果
公开(公告)号：WO2002066110A1
公开(公告)日：2002-08-29
申请号：PCT/US2002/005485
申请日：2002-02-12
申请人： BAXTER INTERNATIONAL INC.
发明人： PIERCE, Jennifer, A. , PATNO, Timothy, J. , CAIRONE, Robert , FOLEY, John, T.
IPC分类号： A61M37/00
CPC分类号： A61M1/3693 , A61M1/02 , A61M1/0209 , A61M1/0222 , A61M1/302 , A61M1/303 , A61M1/308 , A61M1/3603 , A61M1/3633 , A61M1/3696 , A61M1/385 , A61M2202/0427 , A61M2202/0429 , A61M2205/33 , A61M2205/3393 , A61M2205/60 , A61M2230/207 , A61M2202/0014 , A61M2202/0021
摘要： Blood processing systems and methods convey blood drawn from a donor through a blood processing circuit to separate the blood into at least one targeted blood component for collection. The systems and methods derive an estimated effect of the procedure upon the donor. The estimated effect can be expressed in terms of a net blood fluid volume loss, or as a hematodcrit of the donor after completion of the desired blood collection procedure. The systems and methods present the estimated effect to an operator for viewing, reading, or offloading.
摘要翻译：血液处理系统和方法通过血液处理电路传送从供体抽出的血液，将血液分离成至少一个目标血液成分进行收集。这些系统和方法可以估计给予者的程序效应。估计的效果可以表示为净血液体积损失，或作为所需血液收集程序完成后供体的血液代谢。系统和方法对运营商提供了查看，阅读或卸载的估计效果。

9. 发明申请

WO0166172A3 EXTRACORPOREAL BLOOD PROCESSING METHOD AND APPARATUS 审中-公开
标题翻译：超声波血液加工方法和装置
公开(公告)号：WO0166172A3
公开(公告)日：2002-06-06
申请号：PCT/US0107706
申请日：2001-03-09
申请人： GAMBRO INC
发明人： BAINBRIDGE MARLENE , KELLER MURIEL , GORDON TIMOTHY M , MCATEER MICHAEL J , BUTZKE SCOTT
IPC分类号： G01N33/48 , A61M1/02 , A61M1/36 , B04B5/00
CPC分类号： A61M1/3693 , A61M1/30 , A61M1/303 , A61M1/308 , A61M1/3692 , A61M1/3696
摘要： Methods and apparatus particularly involving the separation of blood into blood components and the collection of such components are disclosed. In one aspect, an extracorporeal method for the collection of plasma and red blood cells is provided, wherein the collection of plasma and red blood cells may occur simultaneously or subsequently utilizing the same dual stage blood processing vessel. The flow of blood to the blood processing vessel and return of uncollected blood components may be provided via a single needle, wherein blood is removed from and returned to a donor/patient during alternating blood removal and blood return submodes. Platelet separation and collection options are also described. In either case, prior to red blood cell collection, a set-up phase may be carried out to set a predetermined hematocrit and AC ratio. Replacement fluid delivery may optionally also be provided either substantially continuously during any collection phase(s) and/or in a bolus mode.
摘要翻译：公开了特别涉及将血液分离成血液成分并收集这些组分的方法和装置。一方面，提供了用于收集血浆和红细胞的体外方法，其中血浆和红细胞的收集可以同时发生或随后使用相同的双级血液处理容器。可以经由单个针提供血液加工血液到血液处理容器的流动和未收集的血液成分的返回，其中在交替的血液清除和血液返回子模式期间从血液中取出血液并返回给供体/患者。还描述了血小板分离和收集选项。在任一种情况下，在红细胞收集之前，可以进行设置阶段以设定预定的血细胞比容和AC比。替代流体输送可以任选地在任何收集阶段和/或以推注模式中基本连续地提供。

10. 发明申请

WO01062314A3 HEMODIALYSIS ASSEMBLY AND METHOD 审中-公开
标题翻译：血液透析装置和方法
公开(公告)号：WO01062314A3
公开(公告)日：2002-03-21
申请号：PCT/US2001/040154
申请日：2001-02-20
IPC分类号： A61M1/16 , A61M1/30 , A61M1/34 , A61M1/36 , A61M37/00
CPC分类号： A61M1/3693 , A61M1/16 , A61M1/30 , A61M1/303 , A61M1/34 , A61M1/3403 , A61M1/3406 , A61M1/3479 , A61M1/3696
摘要： A hemodialysis system and method of operation includes supplying whole blood containing blood cells, plasma fluid and foreign substances to a process control preferably having a centrifuge which operates to separate the cells from the plasma fluid and foreign substances. The plasma fluid and foreign substances are then conveyed away from the centrifuge where the foreign substances are removed from the plasma to result in cleaned blood cells and cleaned plasma fluid which may be used in a patient.
摘要翻译：血液透析系统和操作方法包括将含有血细胞，血浆和异物的全血供给到优选具有操作以将细胞与血浆流体和外来物质分离的离心机的过程控制。然后等离子体流体和异物被输送离开离心机，其中外来物质从等离子体中除去，导致清洁的血液细胞和可用于患者的清除的血浆液。

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