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1. 发明申请

WO2012071395A1 SYSTEM AND METHOD FOR REDUCING PULSATILE PRESSURE 审中-公开
标题翻译：减轻压力压力的系统和方法
公开(公告)号：WO2012071395A1
公开(公告)日：2012-05-31
申请号：PCT/US2011/061815
申请日：2011-11-22
申请人： ARIA CV, INC. , SCANDURRA, John , VOLLMERS, Karl
发明人： SCANDURRA, John , VOLLMERS, Karl
IPC分类号： A61F2/06
CPC分类号： A61M29/02 , A61M1/1005 , A61M1/1008 , A61M1/1032 , A61M1/1044 , A61M1/106 , A61M1/107 , A61M1/1072 , A61M1/1074 , A61M1/1086 , A61M1/12 , A61M1/125 , A61M25/04 , A61M25/1018 , A61M25/10184 , A61M2205/33 , A61M2205/3303
摘要： A device for reducing pressure within a lumen includes a reservoir structured for holding a fluid therein, an injection port in fluid communication with the reservoir, a compliant body structured to expand and contract upon changes in pressure, and a conduit extending between and fluidly coupling the reservoir and the compliant body. The fluid may be a compressible or a noncompressible fluid.
摘要翻译：用于减小管腔内的压力的装置包括构造成用于将流体保持在其中的储存器，与储存器流体连通的注射口，构造成在压力变化时膨胀和收缩的顺应性物体，以及在第水库和合规体。流体可以是可压缩的或不可压缩的流体。

2. 发明申请

WO00074747A1 VENTRICULAR ASSIST DEVICE 审中-公开
标题翻译：静脉辅助装置
公开(公告)号：WO00074747A1
公开(公告)日：2000-12-14
申请号：PCT/US2000/011191
申请日：2000-04-26
IPC分类号： A61M1/12 , A61M1/10 , A61M1/36
CPC分类号： A61M1/3659 , A61M1/1008 , A61M1/1037 , A61M1/1044 , A61M1/1049 , A61M1/106 , A61M1/122 , A61M1/127 , A61M2205/8243
摘要： An implanted VAD (preferably an LVAD) (10) includes a compliance chamber (24) which forms a reservoir for liquid extending from adjacent the bottom of the compliance chamber upwardly towards the top of the compliance chamber, a chamber for gas disposed above the liquid reservoir, and extending upwardly to the top of the compliance chamber. The gas chamber is in gaseous communication with a blood pump (20) via a conduit. A subcutaneous port is in liquid, gaseous communication with the liquid reservoir via a second conduit for introducing make-up gas into or removing excess gas from the gas chamber via the liquid reservoir, and for removing accumulated liquid from the liquid reservoir. An outlet cannula (32) comprises a hard polymer tubing commencing adjacent the pump, and a relatively soft graft tubing terminating adjacent the tube adapted to enter the aorta, a distal end of the hard polymer tubing, and a proximal end of the graft tubing being secured together by a snapfit connector. A sewed apical cuff is provided for sewing attachment of the inlet cannula to a chamber of the heart, and a collet ring clamp secures together the distal end of the apical cuff, and the distal end of the tube.
摘要翻译：植入的VAD（优选LVAD）（10）包括顺应性室（24），其形成用于液体从柔性室的底部向上朝向柔顺室的顶部延伸的液体的容器，用于设置在液体上方的气体室储存器，并向上延伸到柔性室的顶部。气室通过导管与血液泵（20）气态连通。皮下端口经由第二导管与液体储存器液体地气态连通，用于将补充气体经由液体储存器引入或去除来自气体室的多余气体，以及从液体储存器中去除积聚的液体。出口插管（32）包括从泵附近开始的硬质聚合物管，以及相邻软管接合管，其邻近管适于进入主动脉，硬聚合物管的远端，以及接合管的近端通过扣件连接器固定在一起。提供缝合的顶端套管用于将入口插管缝合到心脏的腔室，并且夹套环夹具将顶端套管的远端和管的远端固定在一起。

3. 发明申请

WO98041247A1 ARTIFICIAL HEART CAPABLE OF BEING WHOLLY IMPLANTED 审中-公开
标题翻译：人工心脏可以嵌入
公开(公告)号：WO98041247A1
公开(公告)日：1998-09-24
申请号：PCT/FR1998/000544
申请日：1998-03-18
IPC分类号： A61M1/12 , A61M1/10 , F04C2/10
CPC分类号： A61M1/1096 , A61M1/1037 , A61M1/1044 , A61M1/106 , A61M1/1063 , A61M1/1086 , A61M1/12 , A61M1/122 , F04C2/102
摘要： The invention concerns an artificial heart capable of being wholly implanted comprising in a single-piece module (2) two independent ventricular chambers (22G, 22D) each provided with two orifices (11G, 11D, 12G, 12D) equipped with a valve for respectively releasing and pumping blood, the volume of each chamber (22G, 22D) being variable by means of a mobile membrane (17, 18) constituting a wall of the chamber (22G, 22D) and hydraulically actuated by a fluid driven by an actuator comprising a motor and a volumetric pump. The ventricular chambers (22G, 22D) are arranged so as to form an upside-down V, between whose branches are arranged said actuators and the space (37) for the actuating fluid. The chambers (22G, 22D) comprise on the outside convex walls (7G, 7D) whereon are arranged the releasing and pumping orifices (11G, 11D, 12G, 12D).
摘要翻译：本发明涉及一种能够完全植入的人造心脏，其包括在单件模块（2）中的两个独立的室室（22G，22D），每个独立的室室分别设有两个分别装有阀的孔（11G，11D，12G，12D）释放和泵送血液，每个腔室（22G，22D）的体积可通过构成腔室（22G，22D）的壁的可移动膜（17,18）而变化，并由由致动器驱动的流体液压致动器包括电机和容积泵。心室（22G，22D）被布置成在它们的分支布置在所述致动器和致动流体的空间（37）之间形成一个倒置的V。腔室（22G，22D）包括在外侧凸壁（7G，7D）上，其上布置有释放和抽吸孔（11G，11D，12G，12D）。

4. 发明申请

WO1989001765A1 PROSTHETIC COMPLIANCE DEVICES 审中-公开
标题翻译：优势合规设备
公开(公告)号：WO1989001765A1
公开(公告)日：1989-03-09
申请号：PCT/US1988002740
申请日：1988-08-11
申请人： JARVIK, Robert, K.
IPC分类号： A61F02/22
CPC分类号： A61F2/06 , A61F2002/068 , A61M1/1008 , A61M1/1037 , A61M1/1044 , A61M1/1046 , A61M1/1055 , A61M1/107 , A61M1/122
摘要： Implantable prosthetic devices (1A) and methods of use for increasing blood flow by increasing arterial compliance and reducing the magnitude of the pressure pulsations in the arterial system (16), and to increase perfusion of specific organs (10) in order to overcome the deleterious effects of cardiovascular disease, are disclosed.

5. 发明申请

WO1985004812A1 ELECTRONIC CONTROL SYSTEM FOR A CARDIAC PROSTHESIS 审中-公开
标题翻译：电子控制系统用于心脏病预防
公开(公告)号：WO1985004812A1
公开(公告)日：1985-11-07
申请号：PCT/US1985000560
申请日：1985-04-02
申请人： THORATEC LABORATORIES CORPORATION
发明人： THORATEC LABORATORIES CORPORATION , FARRAR, David, J. , ROBINSON, Thomas, C.
IPC分类号： A61M01/12
CPC分类号： A61M1/1044 , A61M1/1037 , A61M1/106 , A61M1/1086 , A61M1/1087 , A61M1/1096 , A61M1/12 , A61M1/122 , A61M1/127 , A61M2205/3334 , A61M2205/8243
摘要： An electronic control system for controlling the operation of a cardiac prosthesis. The cardiac prosthesis includes dominant and subordinate ventricles which receive blood in response to body requirements and an actuation device coupled to the ventricles for ejecting blood from the ventricles. The electronic control system includes sensing devices to determine the volume of blood in the ventricles as a function of time. A control device, which in the preferred embodiment is a programmed microcomputer, includes a clock controller which first determines the filling flow rates of the ventricles from the volume information from the sensing devices. The ventricle with the greatest filling flow rate is selected as the dominant ventricle. The clock controller then adjusts the heart rate of the cardiac prosthesis as a function of the filling flow rate of the dominant ventricle to allow just enough time for the dominant ventricle to fill completely. The control device further includes first and second ejection rate controllers which generate control signals to adjust the ejection rates of the dominant and subordinate ventricles in accordance with the adjusted heart rate so the dominant and subordinate ventricles can eject all blood in the time allowed by the adjusted heart rate. The control signals are supplied to pump motors to control the operation of pump motors which in turn drive the actuation device to eject the blood from the ventricles.

6. 发明申请

WO1982003980A1 HYDRAULICALLY ACTUATED CARDIAC PROSTHESIS 审中-公开
标题翻译：液压驱动心脏疾病
公开(公告)号：WO1982003980A1
公开(公告)日：1982-11-25
申请号：PCT/US1982000629
申请日：1982-05-12
申请人： FOXCROFT ASS
发明人： FOXCROFT ASS , ROBINSON THOMAS C , KITRILAKIS SOTIRIS , MARTIN THOMAS B JR
IPC分类号： A61F01/00
CPC分类号： A61M1/1096 , A61M1/1037 , A61M1/1044 , A61M1/106 , A61M1/1086 , A61M1/12 , A61M1/122 , A61M1/127 , A61M2205/8243
摘要： A cardiac prosthesis having an hydraulically actuated compressible blood pump (RV). An actuation chamber (116) adjacent the blood pump (RV) receives pulses of hydraulic actuation fluid from an actuator pump (120) through a fluid inlet path (126) to compress the blood pump (RV) during systole and eject blood therefrom. Between pulses the actuation fluid is permitted to drain from the actuation chamber (116) through an outlet path (132) into a reservoir (12). Discharge of fluid through the outlet path (132) is controlled by a dump valve (130) which is adapted to close or open the outlet path (132) primarily in response to forces which vary as a function of the flow of actuation fluid through the fluid inlet path (126).
摘要翻译：具有液压致动的可压缩血液泵（RV）的心脏假体。邻近血液泵（RV）的致动室（116）从致动器泵（120）通过流体入口路径（126）接收液压致动流体的脉冲，以在收缩期间压缩血液泵（RV）并从其中喷出血液。在脉冲之间，允许致动流体从致动室（116）通过出口路径（132）排出到储存器（12）中。通过出口路径（132）的流体的排放由排放阀（130）控制，排放阀（130）主要用于关闭或打开出口路径（132），这是因为随着作用流动的作用而变化的作用力流体入口路径（126）。

7. 发明申请

WO2015195783A3 SYSTEMS AND METHODS FOR TREATING PULMONARY HYPERTENSION 审中-公开
标题翻译：用于治疗肺动脉高压的系统和方法
公开(公告)号：WO2015195783A3
公开(公告)日：2016-02-11
申请号：PCT/US2015036201
申请日：2015-06-17
申请人： ARIA CV INC
发明人： VOLLMERS KARL , SCANDURRA JOHN
IPC分类号： A61M39/02 , A61M1/10
CPC分类号： A61M1/1086 , A61B17/12036 , A61B17/1204 , A61B17/12136 , A61B2017/00022 , A61B2017/00212 , A61B2017/00221 , A61B2090/064 , A61M1/1044 , A61M1/1072 , A61M1/125 , A61M5/1723 , A61M5/5086 , A61M25/04 , A61M25/0662 , A61M25/104 , A61M29/02 , A61M39/0208 , A61M2025/0681 , A61M2205/04 , A61M2205/18 , A61M2205/3324 , A61M2205/3327 , A61M2205/3334 , A61M2205/3368 , A61M2205/3389 , A61M2205/3515 , A61M2205/3523 , A61M2205/505 , A61M2210/12 , A61M2230/04
摘要： A system for treating heart disease, such as pulmonary hypertension or right heart failure, including an implantable component and external components for monitoring the implantable component is provided. The implantable component may include a compliant member, e.g., balloon, coupled to a reservoir via a conduit. Preferably, the compliant member is adapted to be implanted in a pulmonary artery and the reservoir is adapted to be implanted subcutaneously. The external components may include a clinical controller component, monitoring software configured to run a clinician's computer, a patient monitoring device, and a mobile application configured to run on a patient's mobile device.
摘要翻译：提供了一种用于治疗心脏病的系统，例如肺动脉高压或右心衰竭，包括可植入组件和用于监测可植入组件的外部组件。可植入部件可以包括通过导管联接到储存器的柔顺构件，例如球囊。优选地，顺应性构件适于植入肺动脉中，并且储库适于被皮下植入。外部部件可以包括临床控制器组件，被配置为运行临床医生的计算机的监视软件，患者监视设备和被配置为在患者的移动设备上运行的移动应用。

8. 发明申请

WO2013078390A3 COUNTERPULSATION DEVICE DRIVER APPARATUS, METHOD AND SYSTEM 审中-公开
标题翻译：计算装置驱动装置，方法和系统
公开(公告)号：WO2013078390A3
公开(公告)日：2014-10-02
申请号：PCT/US2012066367
申请日：2012-11-21
申请人： ABIOMED INC
发明人： SPENCE PAUL , DOWLING ROB , KUNG BOB , HASTIE CAITLYN , SIESS THORSTEN , GRATZ ERIC , SPANIER GERD
IPC分类号： A61N1/362
CPC分类号： A61M1/1086 , A61B17/062 , A61B2017/1107 , A61B2017/1135 , A61M1/10 , A61M1/1008 , A61M1/1037 , A61M1/1044 , A61M1/106 , A61M1/1062 , A61M1/107 , A61M1/12 , A61M1/122 , A61M2205/3337 , A61M2205/502 , A61M2230/06
摘要： A method of operating a counterpulsation device (CPD) in a human or animal subject is disclosed, the method including: receiving a heart beat signal indicative of the heart beat of the subject; providing counterpulsation therapy by controlling the pressure supplied to a CPD drive line in pneumatic communication with the CPD to cause the CPD to alternately fill with blood and eject blood with a timing that is determined at least in part based on the heart beat signal; while providing counterpulsation therapy, receiving a CPD drive line pressure signal indicative of the pressure in the CPD drive line; and adjusting the pressure supplied to the drive line based at least in part on the drive line pressure signal.
摘要翻译：公开了一种在人或动物对象中操作反搏装置（CPD）的方法，所述方法包括：接收指示对象的心跳的心跳信号; 通过控制与CPD气动连通的CPD驱动线路的压力来提供反搏疗法，以使得CPD以至少部分基于心跳信号确定的定时交替地填充血液并喷出血液; 同时提供反搏疗法，接收指示CPD驱动线中的压力的CPD驱动线压力信号; 以及至少部分地基于所述驱动线压力信号来调节供应到所述驱动线的压力。

9. 发明申请

WO2014138155A1 METHODS, SYSTEMS, AND DEVICES RELATING TO A FAIL-SAFE PUMP FOR A MEDICAL DEVICE 审中-公开
标题翻译：与医疗器械的安全泵相关的方法，系统和装置
公开(公告)号：WO2014138155A1
公开(公告)日：2014-09-12
申请号：PCT/US2014/020526
申请日：2014-03-05
申请人： SUNSHINE HEART COMPANY PTY, LTD. , COOK, Martin , PETERS, Will , LAFONTAINE, Dan , MILLER, Phillip , WOODARD, Steven , HALL, Gregory
发明人： COOK, Martin , PETERS, Will , LAFONTAINE, Dan , MILLER, Phillip , WOODARD, Steven , HALL, Gregory
IPC分类号： A61M1/12
CPC分类号： A61M1/122 , A61M1/1044 , A61M1/1048 , A61M1/1051 , A61M1/106 , A61M1/1067 , A61M1/1068 , A61M1/107 , A61M1/1072 , A61M1/1086 , A61M1/12
摘要： The various embodiments herein relate to pumps for use with various medical devices. The pumps can be positive displacement pumps or gear pumps. Each pump has at least one fluid transfer opening defined in the pump that allows for transfer of fluid at a predetermined flow rate that provides for deflation of the device in a predetermined amount of time.
摘要翻译：本文的各种实施例涉及用于各种医疗装置的泵。泵可以是容积式泵或齿轮泵。每个泵具有限定在泵中的至少一个流体传送开口，其允许以预定流量的传送流体，该预定流量在预定量的时间内提供装置的放气。

10. 发明申请

WO2013160411A1 PULSATIONSBLUTPUMPE 审中-公开
公开(公告)号：WO2013160411A1
公开(公告)日：2013-10-31
申请号：PCT/EP2013/058648
申请日：2013-04-25
申请人： ABIOMED EUROPE GMBH
发明人： SPANIER, Gerd
IPC分类号： A61M1/10
CPC分类号： A61M1/1005 , A61M1/1044 , A61M1/1081 , A61M1/1086 , A61M1/122 , A61M1/127 , A61M2205/8243 , A61M2230/04
摘要： Eine extravasale Pulsationsblutpumpe besitzt ein bidirektional wirkendes Pumpsystem (P, M) mit einer Pumpe (P), die über eine erste Leitung (L 1 ) mit dem linken Ventrikel (LV) und über eine zweite Leitung (L 2 ) mit der Aorta (AO) verbunden ist. Mittels einer Steuerung (St) wird die Pumpe (P) entsprechend einem vorgegebenen Herzrythmus abwechselnd in die eine und die andere Richtung betrieben, so dass Blut abwechselnd einerseits durch die erste Leitung (L 1 ) angesaugt und gleichzeitig Blut im selben Maße durch die zweite Leitung (L 2 ) ausgestoßen wird und andererseits Blut durch die zweite Leitung (L 2 ) angesaugt und gleichzeitig Blut durch die erste Leitung (L 1 ) ausgestoßen wird. Die Pulsationsblutpumpe kombiniert die Funktionen und Vorteile einer extravasalen Copulsationspumpe mit denen einer extravasalen Gegenpulsationsblutpumpe.
摘要翻译：血管外Pulsationsblutpumpe具有双作用的泵送系统（P，M）经由第一线路（L1）到左心室（LV）的泵（P），并经由第二线路（L2）到主动脉（AO）连接是。通过控制（ST），该泵（P）对应于一个和另一个方向上交替地操作预定的心脏节律，的装置，使得血液交替，一方面由所述第一线（L1）通过所述第二导管被吸入而血液（以相同的速率 L2）被排出并同时血液通过第一线路（L1）被排出的其他血液通过所述第二线路（L2）被吸入。该Pulsationsblutpumpe结合的特征，并与血管外Gegenpulsationsblutpumpe的血管外Copulsationspumpe的好处。

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