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1. 发明申请

WO2005027736A3 DEVICES AND METHODS FOR FORMING MAGNETIC ANASTOMOSES BETWEEN VESSELS 审中-公开
标题翻译：用于形成船舶之间的磁性分析的装置和方法
公开(公告)号：WO2005027736A3
公开(公告)日：2005-07-21
申请号：PCT/US2004031039
申请日：2004-09-15
申请人： VENTRICA INC , COLE DAVID H , GITTINGS DARIN C , CARSON DEAN F
发明人： COLE DAVID H , GITTINGS DARIN C , CARSON DEAN F
IPC分类号： A61B17/00 , A61B17/064 , A61B17/11 , B60J5/06 , B61D19/02 , A61B17/08
CPC分类号： A61B17/11 , A61B17/00491 , A61B17/064 , A61B17/0643 , A61B17/0644 , A61B2017/00557 , A61B2017/00575 , A61B2017/1107 , A61B2017/1135 , A61B2017/1139 , B60J5/062 , B61D19/026
摘要： Device and method for attaching an anastomotic component to a vessel are provided. The device has a first part (38) positioned within the vessel and a second part, having two separate portions (92A, 92B), is positioned outside the vessel. The anastomosis is created by first trapping one side of the anastomosis between the first and second parts and then repositioning the device as necessary before trapping the other side of the anastomosis. In this manner, the orientation and amount of tissue trapped between the parts can be controlled in two or more independent steps.
摘要翻译：提供了将吻合组件附接到血管的装置和方法。该装置具有位于容器内的第一部分（38），并且具有两个分离部分（92A，92B）的第二部分位于容器外部。通过首先捕获第一部分和第二部分之间的吻合的一侧，然后在捕获吻合的另一侧之前根据需要重新定位装置来产生吻合。以这种方式，可以在两个或更多个独立的步骤中控制被部件之间捕获的组织的取向和量。

2. 发明申请

WO0178801A9 METHOD AND APPARATUS FOR PLACING A CONDUIT 审中-公开
标题翻译：配置管道的方法和装置
公开(公告)号：WO0178801A9
公开(公告)日：2003-08-14
申请号：PCT/US0112158
申请日：2001-04-12
申请人： VENTRICA INC , CARSON DEAN F , REO MICHAEL L , OLSON STEPHEN L , LEPULU KEKE , CREWS SAM T , COLE DAVID H , SHARKAWY A ADAM , GITTINGS DARIN C , FOLEY MARK J
发明人： CARSON DEAN F , REO MICHAEL L , OLSON STEPHEN L , LEPULU KEKE , CREWS SAM T , COLE DAVID H , SHARKAWY A ADAM , GITTINGS DARIN C , FOLEY MARK J
IPC分类号： A61B17/11 , A61B17/00 , A61B19/00 , A61F2/06 , A61M29/00
CPC分类号： A61F2/064 , A61B90/39 , A61B2017/00252 , A61B2017/1107
摘要： Devices and methods for placing a conduit (10) in fluid communication with a target vessel (TV) to communicate the target vessel (TV) with a source of blood. A conduit (10) is coupled to the target vessel (TV) by first (14) and second (16) securing components that compress or sandwich the vessel wall. The conduit (10) can be preshaped to assume a desired orientation when in an unbiased state, for example, to allow the conduit (10) to be deformed during delivery and then regain its desired orientation once deployed. The first (14) and second (16) securing components may be any shape but are preferably elongated in the direction of the vessel axis, e.g., elliptical or rectangular, such that a minimum amount of material is present at the outlet to closely approximate the cross-sectional area of the native target vessel. The securing components (14, 16) do not significantly occlude the target vessel lumen, may be secured to the vessel wall in non-penetrating fashion, and provides a fluid-tight seal around the attachment site. The conduit (10) may comprise tissue, synthetic material, etc., and one or both securing components may be constructed or provided with means for attaching an outologous vessel.
摘要翻译：用于放置导管（10）与目标血管（TV）流体连通以将目标血管（TV）与血源通信的装置和方法。导管（10）通过第一（14）和第二（16）固定部件来紧固到目标血管（TV），压缩或夹住血管壁。当处于无偏压状态时，导管（10）可以预成形为呈现期望的取向，例如允许导管（10）在输送期间变形，然后一旦展开就恢复其期望的取向。第一（14）和第二（16）固定部件可以是任何形状，但是优选地在容器轴线的方向上是细长的，例如椭圆形或矩形的，使得在出口处存在最小量的材料以紧密接近天然目标血管的横截面积。固定部件（14,16）不会明显地堵塞目标血管腔，可以非穿透方式固定到血管壁上，并且在附着部位周围提供流体密封的密封。导管（10）可以包括组织，合成材料等，并且一个或两个固定部件可以被构造或设置有用于附接排便器的装置。

3. 发明申请

WO0021463A9 DEVICES AND METHODS FOR USE IN PERFORMING TRANSMYOCARDIAL CORONARY BYPASS 审中-公开
标题翻译：装置和方法用于执行心肌旁呼吸机旁路
公开(公告)号：WO0021463A9
公开(公告)日：2000-09-21
申请号：PCT/US9922954
申请日：1999-10-12
申请人： VENTRICA INC
发明人： GITTINGS DARIN C , SHARKAWY A ADAM , RAPACKI ALAN R , LAROYA GILBERT S
IPC分类号： A61B17/00 , A61F2/02 , A61F2/06 , A61F2/88 , A61F2/90
CPC分类号： A61F2/064 , A61F2/2493 , A61F2/88 , A61F2/90
摘要： This invention is a trans-myocardial bypass device including retractors (R) used to engage, to support myocardial tissue, and mechanisms (100) for supporting coronary vessels so as to allow precise entry into a vessel lumen. Conduits (240) are provided having a configuration that permits positioning in a heart wall to place a coronary vessel in communication with a heart chamber.
摘要翻译：本发明是一种跨心肌旁路装置，其包括用于接合以支撑心肌组织的牵开器（R）以及用于支撑冠状血管以允许精确进入血管腔的机构（100）。提供具有允许定位在心脏壁中以使冠状血管与心室连通的配置的管道（240）。

4. 发明申请

WO2004045383A3 DEVICES AND METHODS FOR FORMING MAGNETIC ANASTOMOSES BETWEEN VESSELS 审中-公开
标题翻译：用于形成船舶之间的磁性分析的装置和方法
公开(公告)号：WO2004045383A3
公开(公告)日：2005-01-27
申请号：PCT/US0336872
申请日：2003-11-18
申请人： VENTRICA INC , COLE DAVID H , GITTINGS DARIN C , OLSON STEPHEN L , CARSON DEAN F , REO MICHAEL L , LEPULU KEKE , SHARKAWY A ADAM
发明人： COLE DAVID H , GITTINGS DARIN C , OLSON STEPHEN L , CARSON DEAN F , REO MICHAEL L , LEPULU KEKE , SHARKAWY A ADAM
IPC分类号： A61B17/00 , A61B17/064 , A61B17/11 , B60J5/06 , B61D19/02
CPC分类号： A61B17/11 , A61B17/00491 , A61B17/064 , A61B17/0643 , A61B17/0644 , A61B2017/00557 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00876 , A61B2017/1107 , A61B2017/1135 , A61B2017/1139
摘要： An anastomisis device has first (866) and second components which each having first and second parts (868, 870). The first (866) and second components are magnetically attracted to one another. The device forms a throughhole when in use. The first parts of the first and second components are positioned radially outward from the second parts relative to the longitudinal axis with the first parts of the first and second components contacting one another and being magnetically attached to one another. The second parts (870) on the first and second components also being magnetically attacted to one another and are separated by the vessel walls.
摘要翻译：吻合装置具有第一部件（866）和第二部件，每个部件具有第一和第二部件（868,870）。第一个（866）和第二个组件彼此磁吸引。使用时该装置形成通孔。第一和第二部件的第一部分相对于纵向轴线从第二部分径向向外定位，第一和第二部件的第一部分彼此接触并且彼此磁性连接。第一和第二组分上的第二部分（870）也被磁性地彼此接触并被容器壁分开。

5. 发明申请

WO0066009A9 METHODS AND DEVICES FOR FORMING A CONDUIT BETWEEN A TARGET VESSEL AND A BLOOD SOURCE 审中-公开
标题翻译：用于形成目标血管和血液源之间的管道的方法和装置
公开(公告)号：WO0066009A9
公开(公告)日：2002-02-07
申请号：PCT/US0012073
申请日：2000-05-03
申请人： VENTRICA INC
发明人： FOLEY MARK J , GITTINGS DARIN C
IPC分类号： A61B17/00 , A61B17/11 , A61F2/06 , A61B17/04
CPC分类号： A61B17/11 , A61B2017/00252 , A61B2017/1107 , A61F2/064
摘要： This invention is methods, and devices for forming a conduit (18) to place a target vessel in fluid communication with a source of blood, such as the aorta or a heart chamber. The conduit (18) may include a first conduit (118) including synthetic vascular graft material, such as PTFE, coupled to a second conduit (110) in the form of a hollow tissue structure, such as an autologous vessel. The first conduit (118) is secured to the target vessel. The second conduit (110) is secured to the first conduit (118), and is placed in fluid communication with a blood source.
摘要翻译：本发明是用于形成导管（18）的方法和装置，以将目标血管置于与诸如主动脉或心室的血液源流体连通。导管（18）可以包括第一导管（118），第一导管（118）包括合成的血管移植材料，例如PTFE，其以诸如自体血管的中空组织结构形式的第二导管（110）联接。第一导管（118）固定到目标容器。第二导管（110）固定到第一导管（118）上并与血液源流体连通。

6. 发明申请

WO0041632A9 METHODS AND DEVICES FOR BYPASSING AN OBSTRUCTED TARGET VESSEL BY PLACING THE VESSEL IN COMMUNICATION WITH A HEART CHAMBER CONTAINING BLOOD 审中-公开
标题翻译：通过在含有血液的心室进行通气的血管中排除阻塞目标血管的方法和装置
公开(公告)号：WO0041632A9
公开(公告)日：2001-08-30
申请号：PCT/US0001073
申请日：2000-01-14
申请人： VENTRICA INC
发明人： GITTINGS DARIN C , BUCH WALLY S , SHARKAWY A ADAM , RAPACKI ALAN R
IPC分类号： A61B17/00 , A61B17/11 , A61B17/12 , A61F2/06 , A61F2/07 , A61F2/86 , A61F2/91 , A61B17/08
CPC分类号： A61B17/11 , A61B2017/00252 , A61B2017/1107 , A61B2017/1135 , A61F2/064 , A61F2/07 , A61F2/86 , A61F2/91
摘要： Methods, and devices (10) for forming an anastomosis during a bypass procedure utilize a graft vessel (18) secured to a vessel coupling (130) adapted to be fixed to a target vessel without using suture. The vessel coupling (130) may be a stent (132) with the graft vessel (18) secured thereto to form a stent/graft assembly (22). The vessel coupling (130) may be collapsed, and then expanded.
摘要翻译：用于在旁路过程中形成吻合的方法和装置（10）利用固定到适合于固定到目标血管而不使用缝线的血管联接器（130）的移植血管（18）。血管联接器（130）可以是支架（132），其中移植物容器（18）固定到支架（132）上以形成支架/移植物组件（22）。容器联接器（130）可以折叠，然后膨胀。

7. 发明申请

WO0041633A9 METHODS AND DEVICES FOR FORMING VASCULAR ANASTOMOSES 审中-公开
标题翻译：用于形成血管平滑肌的方法和装置
公开(公告)号：WO0041633A9
公开(公告)日：2001-07-12
申请号：PCT/US0000991
申请日：2000-01-14
申请人： VENTRICA INC
发明人： GITTINGS DARIN C , BUCH WALLY S , RAPACKI ALAN R
IPC分类号： A61B17/00 , A61B17/11 , A61F2/06 , A61F2/86 , A61B17/08
CPC分类号： A61B17/11 , A61B2017/00252 , A61B2017/1107 , A61B2017/1135 , A61F2/064 , A61F2/07 , A61F2/86 , A61F2/91
摘要： Methods, and devices (10) for forming an anastomosis utilize a graft vessel (18) secured to a vessel coupling (130) that is fixed to a target vessel without using suture. The vessel coupling (130) may be collapsed, and then expanded. The vessel coupling (130) may be a stent (132) attached to a graft vessel (18) to form a stent/graft assembly (22).
摘要翻译：用于形成吻合的方法和装置（10）利用固定到固定到目标血管而不使用缝合线的血管联接器（130）的移植血管（18）。容器联接器（130）可以折叠，然后膨胀。血管联接（130）可以是附接到移植物容器（18）以形成支架/移植物组件（22）的支架（132）。

8. 发明申请

WO2004105693A3 COMPONENTS, SYSTEMS AND METHODS FOR FORMING ANASTOMOSES USING MAGNETISM OR OTHER COUPLING MEANS 审中-公开
标题翻译：使用磁铁或其他耦合方式形成分析物的组件，系统和方法
公开(公告)号：WO2004105693A3
公开(公告)日：2005-11-10
申请号：PCT/US2004016204
申请日：2004-05-22
申请人： VENTRICA INC , SHARKAWY A ADAM , STINE J GREG , COLE DAVID H , CREWS SAMUEL , GITTINGS DARIN C , KESSLER ADAM , FOLEY MARK
发明人： SHARKAWY A ADAM , STINE J GREG , COLE DAVID H , CREWS SAMUEL , GITTINGS DARIN C , KESSLER ADAM , FOLEY MARK
IPC分类号： A61B17/00 , A61B17/04 , A61B17/064 , A61B17/068 , A61B17/08 , A61B17/11 , A61F2/00 , A61F2/06 , A61F2/82 , A61K20060101 , A61M25/18 , A61M39/00 , H01F41/02
CPC分类号： A61B17/0057 , A61B17/00491 , A61B17/0469 , A61B17/064 , A61B17/0643 , A61B17/0644 , A61B17/068 , A61B17/11 , A61B2017/00252 , A61B2017/00876 , A61B2017/044 , A61B2017/0648 , A61B2017/1107 , A61B2017/1132 , A61B2017/1135 , A61B2017/1139 , A61F2/064 , A61F2/07 , A61F2/89 , A61F2/90 , A61F2002/061 , A61F2002/067 , A61F2002/075 , A61F2002/30079 , A61F2002/821 , A61F2210/009 , A61F2230/005 , A61F2230/0067 , H01F41/026
摘要： Anastomotic components may be attached to hollow bodies or vessels by magnetic or mechanical force to create an anastomosis, form a port in a vessel, or repair a diseased vessel lumen. Anastomoses are created by coupling a first connector (376) to an end of a vessel and then attracting it to a second connector secured to the side wall of another vessel. The connection between the first and second connectors may be solidly magnetic, solely mechanical, or a combination thereof. Also disclosed are methods and devices for treating diseased vessel lumens, for example abdominal aortic aneurysm. A plurality of docking members (280, 300, 310, 320) is attached to the vessel at solicited positions, and then one or more grafts is secured to the docking members in any suitable manner.
摘要翻译：吻合组件可以通过磁力或机械力连接到中空体或血管，以产生吻合，在血管中形成端口或修复患病血管腔。通过将第一连接器（376）联接到容器的端部，然后将其吸引到固定到另一个容器的侧壁的第二连接器来产生吻合。第一和第二连接器之间的连接可以是固体磁性的，机械的或它们的组合。还公开了用于治疗患病血管腔的方法和装置，例如腹主动脉瘤。多个对接构件（280,3300,310,320）在被请求的位置附接到容器，然后以任何合适的方式将一个或多个移植物固定到对接构件。

9. 发明申请

WO2004096013A2 METHODS AND DEVICES FOR TEMPORARILY SEALING A BLOOD VESSEL DURING AN ANASTOMOSIS 审中-公开
标题翻译：方法和设备在临床诊断期间临时密封血管
公开(公告)号：WO2004096013A2
公开(公告)日：2004-11-11
申请号：PCT/US2004012843
申请日：2004-04-26
申请人： VENTRICA INC , CARSON DEAN F , REO MICHAEL , COLE DAVID H , GITTINGS DARIN C , FOLEY MARK
发明人： CARSON DEAN F , REO MICHAEL , COLE DAVID H , GITTINGS DARIN C , FOLEY MARK
IPC分类号： A61B20060101 , A61B17/11 , A61B17/12 , A61B
CPC分类号： A61B17/12022 , A61B17/11 , A61B17/12036 , A61B17/1204 , A61B17/12172 , A61B2017/00646 , A61B2017/00876
摘要： A sealing device is used to temporarily seal an opening in a body cavity or lumen such as the aorta when performing an anastomosis. The sealing device may include an intravascular component and an extravascular component which are magnetically attracted to one another. Another sealing device has a connector extending through the opening which is used to create the anastomosis. The connector may simply use tension to provide a clamping force between the intravascular and extravascular components or the connector may simply be a spring.
摘要翻译：当进行吻合时，密封装置用于临时密封诸如主动脉的体腔或内腔中的开口。密封装置可以包括彼此磁吸引的血管内成分和血管外成分。另一个密封装置具有延伸穿过开口的连接器，用于产生吻合。连接器可以简单地使用张力来在血管内和血管外部件之间提供夹紧力，或者连接器可以仅仅是弹簧。

10. 发明申请

WO0021461A9 DELIVERING A CONDUIT INTO A HEART WALL TO PLACE A CORONARY VESSEL IN COMMUNICATION WITH A HEART CHAMBER AND REMOVING TISSUE FROM THE VESSEL OR HEART WALL TO FACILITATE SUCH COMMUNICATION 审中-公开
标题翻译：将心脏输送到心房内，放置一个通过心室进行通讯的冠脉血管，并从血管或心脏移除组织以便于进行此类通讯
公开(公告)号：WO0021461A9
公开(公告)日：2000-09-14
申请号：PCT/US9922953
申请日：1999-10-12
申请人： VENTRICA INC
发明人： RAPACKI ALAN R , GITTINGS DARIN C , LAROYA GILBERT S , FOLEY MARK J
IPC分类号： A61B17/00 , A61B17/08 , A61B17/34 , A61F20060101 , A61F2/00 , A61F2/02 , A61F2/06 , A61F2/24 , A61F2/94 , A61F11/00 , A61M1/10 , A61M5/00 , A61F
CPC分类号： A61F2/064 , A61B17/3468 , A61B2017/00247 , A61B2017/00252 , A61B2018/00392 , A61B2090/062 , A61F2/2493 , A61F2/90 , A61F2/94 , A61F2/966 , A61F2002/30079 , A61F2002/30617 , A61F2002/9517 , A61F2210/009 , A61F2250/0097
摘要： Devices and methods for delivering conduits into the wall of a patient's heart to communicate a coronary vessel with a heart chamber. The devices are passed through the coronary vessel and the heart wall to place the conduit and establish a blood flow path between the vessel and the heart chamber. Additional devices and methods are provided for removing tissue from a coronary vessel or the heart wall to establish a flow path between the coronary vessel in communication with the heart chamber.
摘要翻译：将导管输送到患者心脏的壁中以将心脏腔室的冠状动脉血管传送的装置和方法。装置通过冠状血管和心脏壁以放置导管，并在容器和心脏腔室之间建立血流路径。提供了附加的装置和方法，用于从冠状血管或心脏壁去除组织，以建立与心室连通的冠状血管之间的流动路径。

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