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1. 发明申请

WO2012176195A3 CLOSURE ELEMENT FOR USE WITH ANNULOPLASTY STRUCTURE 审中-公开
公开(公告)号：WO2012176195A3
公开(公告)日：2012-12-27
申请号：PCT/IL2012/000250
申请日：2012-06-21
申请人： VALTECH CARDIO, LTD. , GROSS, Amir , SHEPS, Tal , HAMMER, Tal , REICH, Tal , IFLAH, Ehud , HERMAN, Yaron , POMERANTZ, Uriel, Aba , CABIRI, Oz
发明人： GROSS, Amir , SHEPS, Tal , HAMMER, Tal , REICH, Tal , IFLAH, Ehud , HERMAN, Yaron , POMERANTZ, Uriel, Aba , CABIRI, Oz
IPC分类号： A61F2/24
摘要： Apparatus is provided including an implantable structure (22), including a flexible sleeve (26), having first and second sleeve ends (49, 51), a contracting assembly (40), which is configured to longitudinally contract the sleeve (26). The contracting assembly (40) includes a contracting mechanism (28), which is at a first site of the sleeve (26); and a longitudinal contracting member (30), having (a) a first member end, (b) a second member end (53), coupled to the sleeve (26) at a second site longitudinally between the first site and the second sleeve end (49 or 51), exclusive. A force -distributing element (540) is couplable to the sleeve (26) in a vicinity of the second sleeve end (49 or 51), element (540) is configured to distribute a contraction force by the contracting member (30) between the second member end (53) and the second sleeve end (49 or 51). Other applications are also described.

2. 发明申请

WO2012014201A3 MULTIPLE ANCHOR DELIVERY TOOL 审中-公开
公开(公告)号：WO2012014201A3
公开(公告)日：2012-02-02
申请号：PCT/IL2011/000600
申请日：2011-07-26
申请人： VALTECH CARDIO, LTD. , CABIRI, Oz , GROSS, Amir , HAMMER, Tal , REICH, Tal , IFLAH, Ehud
发明人： CABIRI, Oz , GROSS, Amir , HAMMER, Tal , REICH, Tal , IFLAH, Ehud
IPC分类号： A61B17/04
摘要： An anchor deployment tool (30) includes a flexible outer tube (34), within which is positioned a flexible inner shaft (36), and a rotating deployment element (38) coupled to a distal end (39) of the shaft. The tool (30) is configured to provide an anchor storage area (40), which initially stores a plurality of tissue anchors (32), such that the inner shaft (36) passes through channels of the anchors along entire longitudinal lengths of the anchors (32), and the anchors are within the outer tube (34). The rotating deployment element (38) is configured to directly engage the anchors (32) in the anchor storage area (40) one at a time, advance each of the anchors while engaged in a distal direction, and deploy each of the anchors through the distal tube end (42) and into tissue of a subject. Other embodiments are also described.

3. 发明申请

WO2010073246A2 ADJUSTABLE ANNULOPLASTY DEVICES AND ADJUSTMENT MECHANISMS THEREFOR 审中-公开
标题翻译：可调节的ANNULOPLASTY设备及其调整机制
公开(公告)号：WO2010073246A2
公开(公告)日：2010-07-01
申请号：PCT/IL2009/001209
申请日：2009-12-22
申请人： VALTECH CARDIO, LTD. , CABIRI, Oz , SHEPS, Tal , KUTZIK, Meir , GROSS, Amir , GROSS, Yossi , ZIPORY, Yuval
发明人： CABIRI, Oz , SHEPS, Tal , KUTZIK, Meir , GROSS, Amir , GROSS, Yossi , ZIPORY, Yuval
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61B17/0401 , A61B2017/00243 , A61B2017/0409 , A61B2017/0414 , A61B2017/0441 , A61B2017/0464 , A61B2017/0496 , A61B2017/0649 , A61B2017/12095 , A61F2/2442 , A61F2/2466 , A61F2250/0004 , A61F2250/001
摘要： Apparatus is provided including an implant structure (22, 122, 1122), a rotatable structure (2900) coupled to the implant structure (22, 122, 1122) in a vicinity of a first portion thereof, and a flexible member (30). At least a first portion of the 5 flexible member (30) is disposed in contact with the rotatable structure (2900), and at least one end portion of the flexible member (30) is not disposed in contact with the rotatable structure (30). In response to rotation of the rotatable structure (2900) in a first direction thereof, successive portions of the flexible member (30) contact the rotatable structure (2900) to pull the at least one end portion of the flexible member 0 (30) toward the first portion of the implant structure (22, 122, 1122), and responsively to draw the first and second portions of the implant structure (22, 122, 1122) toward each other. Other applications are also described.
摘要翻译：提供了包括植入结构（22,122,1122）的装置，在其第一部分附近与植入结构（22,122,1122）相连的可旋转结构（2900）和柔性构件（30）。所述柔性构件（30）的至少第一部分设置成与所述可旋转结构（2900）接触，并且所述柔性构件（30）的至少一个端部未设置成与所述可旋转结构（30）接触，。响应于可旋转结构（2900）沿其第一方向的旋转，柔性构件（30）的连续部分接触可旋转结构（2900）以将柔性构件0（30）的至少一个端部向着植入结构（22,122,1122）的第一部分，并且响应于将植入物结构（22,122,1122）的第一和第二部分彼此拉出。还描述了其它应用。

4. 发明申请

WO2010128503A2 DEPLOYMENT TECHNIQUES FOR ANNULOPLASTY RING AND OVER-WIRE ROTATION TOOL 审中-公开
标题翻译：用于静脉曲张和超线性旋转工具的部署技术
公开(公告)号：WO2010128503A2
公开(公告)日：2010-11-11
申请号：PCT/IL2010/000358
申请日：2010-05-04
申请人： VALTECH CARDIO, LTD. , ZIPORY, Yuval , CABIRI, Oz , GROSS, Yossi , HAMMER, Tal , GROSS, Amir , MAISANO, Francesco , MILLER, Eran , WEITZMAN, Yoseph , AYVAZIAN, Aram
发明人： ZIPORY, Yuval , CABIRI, Oz , GROSS, Yossi , HAMMER, Tal , GROSS, Amir , MAISANO, Francesco , MILLER, Eran , WEITZMAN, Yoseph , AYVAZIAN, Aram
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61B17/00234 , A61B17/0401 , A61B17/064 , A61B17/068 , A61B17/072 , A61B2017/00243 , A61B2017/0409 , A61B2017/0414 , A61B2017/0441 , A61B2017/0443 , A61B2017/0464 , A61B2017/0496 , A61B2017/0647 , A61B2017/0648 , A61B2017/0649 , A61B2017/12095 , A61B2017/2923 , A61F2/2409 , A61F2/2412 , A61F2/2445 , A61F2/2451 , A61F2/2457 , A61F2/2466 , A61F2002/30537 , A61F2220/0016 , A61F2250/0004
摘要： Apparatus is provided including an implant structure (22, 500), which includes a contracting mechanism (40), which comprises a rotatable structure (46, 810, 936), arranged such that rotation of the rotatable structure (46, 810, 936) contracts the implant structure (22, 500). A longitudinal member (86) is coupled to the contracting mechanism (40). A tool (80) for rotating the rotatable structure (46, 810, 936) is configured to be guided along the longitudinal member (86), to engage the rotatable structure (46, 810, 936), and to rotate the rotatable structure (46, 810, 936) in response to a rotational force applied to the tool (80). Other applications are also described.
摘要翻译：提供了包括植入结构（22,500）的设备，其包括收缩机构（40），该收缩机构包括可旋转结构（46,810,936），其可旋转结构（46,810,936）收缩植入物结构（22,500）。纵向构件（86）联接到收缩机构（40）。用于旋转可旋转结构（46,810,936）的工具（80）被构造成沿着纵向构件（86）被引导以接合可旋转结构（46,810,936），并且使可旋转结构（ 46,810,936）响应于施加到工具（80）的旋转力。还描述了其它应用。

5. 发明申请

WO2010004546A1 ANNULOPLASTY DEVICES AND METHODS OF DELIVERY THEREFOR 审中-公开
标题翻译： ANNULOPLASTY设备及其递送方法
公开(公告)号：WO2010004546A1
公开(公告)日：2010-01-14
申请号：PCT/IL2009/000593
申请日：2009-06-15
申请人： VALTECH CARDIO, LTD. , GROSS, Amir , BEINART, Iftah , MILLER, Eran , CABIRI, Oz , ELIACHAR, Eliahu , LILACH, Nir , GROSSFELD, Ram , GOLOM, Dmitry , MEYER-BRODNITZ, Gideon , MOSAIUF, Arnon
发明人： GROSS, Amir , BEINART, Iftah , MILLER, Eran , CABIRI, Oz , ELIACHAR, Eliahu , LILACH, Nir , GROSSFELD, Ram , GOLOM, Dmitry , MEYER-BRODNITZ, Gideon , MOSAIUF, Arnon
IPC分类号： A61M25/00
CPC分类号： A61F2/2442 , A61B17/3468 , A61B2017/00243 , A61F2/2445 , A61F2/2466 , A61F2220/0008 , A61F2250/001
摘要： Apparatus is provided, including a tube (421) shaped to define a tube lumen at least one implant (100) reversibly coupled to the tube (421), and configured for implantation within a body of a patient. The apparatus also comprises two or more longitudinal guide members (470) disposed at least in part along a distal portion of the tube (421), the longitudinal guide members (470) having distal portions thereof configured to be reversibly coupled to the implant (100), and arranged such that application of a force to a first one of the longitudinal guide members (470) steers the distal portion of the tube (421) toward a first location along the implant (100), and application of a force to a second one of the longitudinal guide members (470) steers the distal portion of the tube (421) toward a second location along the implant (100). Other embodiments are also described.
摘要翻译：提供了一种装置，其包括成形为限定管内腔的管（421），至少一个可逆地联接到管（421）的植入物（100），并且被配置为植入患者体内。该装置还包括至少部分地沿着管（421）的远端部分设置的两个或更多个纵向引导构件（470），纵向引导构件（470）的远侧部分构造成可逆地联接到植入物（100）），并且布置成使得向纵向引导构件（470）中的第一个施加力朝向沿着植入物（100）的第一位置转向管（421）的远侧部分，并且施加力到纵向引导构件（470）中的第二个引导管（421）的远端部分朝向植入物（100）的第二位置。还描述了其它实施例。

6. 发明申请

WO2008068756A2 SEGMENTED RING PLACEMENT 审中-公开
标题翻译： SEGMENTED环配置
公开(公告)号：WO2008068756A2
公开(公告)日：2008-06-12
申请号：PCT/IL2007/001503
申请日：2007-12-05
申请人： VALTECH CARDIO, LTD. , GROSS, Amir , BEINART, Iftah , ELIACHAR, Eliahu , LILACH, Nir , GROSSFELD, Ram , GOLOM, Dmitry , MEYER-BRODNITZ, Gideon , MOSAIUF, Arnon
发明人： GROSS, Amir , BEINART, Iftah , ELIACHAR, Eliahu , LILACH, Nir , GROSSFELD, Ram , GOLOM, Dmitry , MEYER-BRODNITZ, Gideon , MOSAIUF, Arnon
IPC分类号： A61F2/28
CPC分类号： A61F2/2445 , A61B17/064 , A61B17/068 , A61B2017/00783 , A61B2017/0649 , A61F2/2466 , A61F2250/006
摘要： Apparatus is provided for repairing a valve (30) of a patient, the valve (30) including an annulus (40) and at least first and second leaflets (32 and 34). The apparatus includes at least a first discrete segment (430) and a second discrete segment (440) of an annuloplasty structure (408), each segment being shaped to provide a respective lateral wall (462), each lateral wall (462) being shaped to define at least one lumen of the respective segment (430 and 440). The apparatus further includes at least a first and a second control wire (480 and 490), each control wire (480 and 490) configured for sliding advancement through both the first and second segments (430 and 440). The first control wire (480) is configured to control a relative disposition of a first end (432) of the first segment (430) and a first end (442) of the second segment (440). The second control wire (490) is configured to control a relative disposition of a second end (434) of the first segment (430) and a second end (444) of the second segment (440). Other embodiments are also described.
摘要翻译：提供了用于修复患者的阀（30）的装置，所述阀（30）包括环（40）和至少第一和第二传单（32和34）。所述装置包括瓣膜成形术结构（408）的至少第一离散区段（430）和第二离散区段（440），每个区段被成形为提供相应的侧壁（462），每个侧壁（462）成形以限定相应段（430和440）的至少一个内腔。该装置还包括至少第一和第二控制线（480和490），每个控制线（480和490）被配置用于通过第一和第二段（430和440）滑动前进。第一控制线（480）被配置为控制第一段（430）的第一端（432）和第二段（440）的第一端（442）的相对布置。第二控制线（490）被配置为控制第一段（430）的第二端（434）和第二段（440）的第二端（444）的相对布置。还描述了其它实施例。

7. 发明申请

WO2016059639A1 LEAFLET-RESTRAINING TECHNIQUES 审中-公开
标题翻译：叶片限制技术
公开(公告)号：WO2016059639A1
公开(公告)日：2016-04-21
申请号：PCT/IL2015/051027
申请日：2015-10-14
申请人： VALTECH CARDIO LTD.
发明人： GROSS, Amir , REICH, Tal , HERMAN, Yaron , IFLAH, Ehud , BRAUON, Haim , KUTZIK, Meir , IAMBERGER, Meni
IPC分类号： A61F2/24
CPC分类号： A61F2/2454 , A61B17/068 , A61B2017/00292 , A61B2017/0647 , A61B2017/0649 , A61F2/2445 , A61F2/2451 , A61F2/2457 , A61F2/2466 , A61F2220/0016
摘要： Apparatus, comprising: (i) a catheter (64); (ii) an implant (100), comprising a flexible longitudinal member (102), and a linking member (104) that extends from a first linking site (106a) of the longitudinal member to a second linking site (106b) of the longitudinal member, the implant having: (a) a delivery state in which the longitudinal member is coaxial with the catheter, and at least a portion of the linking member is disposed alongside the longitudinal member, and (b) an implanted state in which a first distance between the first linking site and the second linking site, measured along the longitudinal member, is greater than a second distance between the first linking site and the second linking site, measured along the linking member; and (iii) a plurality of tissue anchors (46), slidable through the catheter and with respect to the longitudinal member. Other embodiments are also described.
摘要翻译：装置，包括：（i）导管（64）; （ii）包括柔性纵向构件（102）的植入物（100）和从所述纵向构件的第一连接位置（106a）延伸到所述纵向构件（102）的第二连接位置（106b）的连接构件（104）所述植入物具有：（a）所述纵向构件与所述导管同轴的输送状态，并且所述连接构件的至少一部分与所述纵向构件一起设置，以及（b）植入状态，其中第一沿着纵向构件测量的第一连接位点和第二连接位点之间的距离大于沿着连接构件测量的第一连接位点和第二连接位点之间的第二距离; 和（iii）可以穿过导管并相对于纵向构件滑动的多个组织锚固件（46）。还描述了其它实施例。

8. 发明申请

WO2014064694A2 CONTROLLED STEERING FUNCTIONALITY FOR IMPLANT-DELIVERY TOOL 审中-公开
标题翻译：用于植入式工具的控制转向功能
公开(公告)号：WO2014064694A2
公开(公告)日：2014-05-01
申请号：PCT/IL2013/050860
申请日：2013-10-23
申请人： VALTECH CARDIO, LTD.
发明人： SHEPS, Tal , HAMMER, Tal , REICH, Tal , IFLAH, Ehud , GROSS, Amir , HERMAN, Yaron , KOIFMAN, Alexei , ZIPORY, Yuval
IPC分类号： C25B1/04
CPC分类号： A61F2/2436 , A61B17/068 , A61B2017/00039 , A61B2017/00044 , A61B2017/00199 , A61B2017/00327 , A61B2017/00398 , A61B2017/00477 , A61B2017/0649 , A61B2034/2051 , A61B2090/066 , A61B2090/0807 , A61B2090/0811 , A61B2090/3966 , A61F2/2427 , A61F2/2445 , A61F2/2466 , A61M25/0133 , A61M25/0147 , A61M25/04 , A61M25/06 , A61M25/0662 , A61M29/00 , A61M2025/015 , A61M2025/0681 , Y02E60/366
摘要： A catheter (14), advanced toward an anatomical site, has a proximal end and a steerable distal end. An anchor (32, 2332) is advanced through the catheter. An anchor driver (36) drives the anchor out of the catheter's distal end (104), anchoring the anchor at the site. A first constraining member (1602, 1652) engages tissue, and inhibits, after the anchor has been driven out of the catheter and before the anchoring, movement of at least the anchor driver's distal end, on a first axis between the anchor driver's distal end and a site at which the first constraining member engages the tissue. A second constraining member (26) inhibits, after the anchor has been driven out of the catheter and before the anchoring, movement of at least the anchor driver's distal end, on a second axis. Other embodiments are also described.
摘要翻译：朝向解剖部位前进的导管（14）具有近端和可操纵的远端。锚（32,2332）通过导管前进。锚定器驱动器（36）将锚固器从导管的远端（104）驱动，将锚固件锚定在现场。第一约束构件（1602,1652）接合组织，并且在锚固件已被驱出导管之后并且在锚固之前阻止至少锚固器驱动器的远端在锚固器驱动器的远端之间的第一轴线上的运动以及第一约束构件接合组织的位置。第二约束构件（26）在锚固件已被驱出导管之后并且在锚定之前禁止至少锚固器驱动器的远端在第二轴线上的运动。还描述了其它实施例。

9. 发明申请

WO2006097931A2 MITRAL VALVE TREATMENT TECHNIQUES 审中-公开
标题翻译：麻药处理技术
公开(公告)号：WO2006097931A2
公开(公告)日：2006-09-21
申请号：PCT/IL2006/000342
申请日：2006-03-15
申请人： GROSS, Amir , GROSS, Yossi
发明人： GROSS, Amir , GROSS, Yossi
IPC分类号： A61B17/28
CPC分类号： A61F2/2442 , A61B2017/00243 , A61F2/24 , A61F2/2409 , A61F2/2418 , A61F2/2445 , A61F2/2448 , A61F2/2457 , A61F2/2466 , A61F2220/0008 , A61F2220/0025 , A61F2250/0003 , A61F2250/0004 , A61F2250/0007 , A61F2250/0096
摘要： Apparatus (20) is provided for treating mitral valve regurgitation, including a band (30) having distal and proximal ends, the band (30) adapted to be placed: around between 90 and 270 degrees of a mitral valve (58), including around at least a portion of a posterior cusp (56) of the valve (58), in a space defined by (a) a ventricular wall (70), (b) a ventricular surface of the posterior cusp (56) in a vicinity of an annulus (60) of the mitral valve (58), and (c) a plurality of third-order chordae tendineae (74). The apparatus (20) further includes distal and proximal coupling elements (32, 34), coupled to the band (30) at the distal and proximal ends thereof, respectively, and adapted to be coupled to a first chorda tendinea and a second chorda tendinea, respectively, each of the first and second chordae tendineae selected from the group consisting of: one of the plurality of third-order chordae tendineae (74), and a first-order chorda tendinea that inserts on a commissural cusp (78) of the mitral valve (58). Additional embodiments are also described.
摘要翻译：提供了用于治疗二尖瓣反流的装置（20），包括具有远端和近端的带（30），所述带（30）适于被放置：二尖瓣（58）的大约在90度和270度之间，包括围绕在（a）心室壁（70），（b）后边缘（56）的心室表面限定的空间中，阀（58）的后尖瓣（56）的至少一部分在二尖瓣（58）的环（60）和（c）多个三级腱索（74）。装置（20）还包括远端和近端联接元件（32,34），其分别在其远端和近端连接到带（30），并且适于联接到第一腱索和第二腱索，第一和第二腱索腱索中的每一个选自下列组中的一个：多个三级腱索：中的一个（74），和一次腱索，其插入在所述第二腱索的连合尖端（78）上二尖瓣（58）。还描述了另外的实施例。

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