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1. 发明申请

WO2020240282A2 TISSUE ANCHOR HANDLING SYSTEMS AND METHODS 审中-公开
公开(公告)号：WO2020240282A2
公开(公告)日：2020-12-03
申请号：PCT/IB2020/000472
申请日：2020-05-08
申请人： VALTECH CARDIO, LTD.
发明人： BRAUON, Haim , AVIV, Ehud , MURPHY, Brian Patrick , DE SILVA, Praveen , DANG, Kevin K. , AZANKI, Omar Fawzi , GOLAN, Tomer , NESS, Aaron Anan , REICH, Tal , MOLINA, Luis , SHAFIGH, Sam
IPC分类号： A61B17/04 , A61B50/30 , A61B50/20 , A61B90/53
摘要： An apparatus is provided for use with an anchor-handling device (20). The apparatus includes a holder (90) shaped to define a space (92) for receiving the anchor-handling device (20). The holder (90) includes a coupling (94) configured to reversibly couple the anchor- handling device (20) to the holder (94). The apparatus also includes a wearable article (100) coupled to the holder (90). The wearable article (100) is configured to temporarily affix the anchor-handling device (20) to a body of an operating physician that is using the anchor-handling device (20). Other applications are also described.

2. 发明申请

WO2019145947A1 CONTRACTION OF AN ANNULOPLASTY STRUCTURE 审中-公开
公开(公告)号：WO2019145947A1
公开(公告)日：2019-08-01
申请号：PCT/IL2019/050092
申请日：2019-01-23
申请人： VALTECH CARDIO, LTD.
发明人： PELEG, Carmel , COHEN, Yehuda , BRAUON, Haim , ZIPORY, Yuval , SHEPS, Tal
IPC分类号： A61F2/24
摘要： An annuloplasty structure includes a flexible sleeve (25) and an elongate contraction wire (26). The sleeve has a first sleeve-end-portion (42), a second sleeve-end-portion (44), and a circumferential wall (46) that defines a longitudinal lumen (48) between the first and second sleeve-end-portions. The contraction wire has a first wire-end (52) and a second wire-end (54), the first wire-end being attached to the sleeve at the first sleeve-end-portion. The wire extends, in association with the circumferential wall, from the first sleeve-end- portion to the second sleeve-end-portion. The wire is arranged with respect to the sleeve such that increasing a longitudinal proportion of the wire that is disposed within the lumen longitudinally contracts the sleeve. Other embodiments are also provided.

3. 发明申请

WO2019145941A1 TECHNIQUES FOR FACILITATING HEART VALVE TETHERING AND CHORD REPLACEMENT 审中-公开
公开(公告)号：WO2019145941A1
公开(公告)日：2019-08-01
申请号：PCT/IL2019/050083
申请日：2019-01-22
申请人： VALTECH CARDIO, LTD.
发明人： REICH, Tal
IPC分类号： A61F2/24 , A61B5/107 , A61B17/04 , A61B17/00 , A61B17/122 , A61B90/00
CPC分类号： A61F2/2457 , A61B5/1076 , A61B6/487 , A61B17/0401 , A61B17/122 , A61B2017/00243 , A61B2017/00783 , A61B2017/0409 , A61B2017/0441 , A61B2017/0464 , A61B2090/061 , A61B2090/3966 , A61F2/2466 , A61F2/2496
摘要： A method is described, for use with a native valve (10) of a heart (4) of a subject, the valve being disposed between an atrium (6) and a ventricle (8) of the heart. A first radiopaque marker (32) and a second radiopaque marker (34) are percutaneously advanced to the heart. The first radiopaque marker is placed against a tissue site (42) in the ventricle. The second radiopaque marker is placed against a leaflet (12) of the valve. A distance is measured between the first radiopaque marker at the tissue site, and the second radiopaque marker at the leaflet. Responsively to the measured distance, a chord-length is determined. An artificial chord (60), selected based on the chord-length, is implanted in the heart. Other embodiments are also described.

4. 发明申请

WO2016174669A1 ANNULOPLASTY TECHNOLOGIES 审中-公开
标题翻译： ANNULOPLASTY技术
公开(公告)号：WO2016174669A1
公开(公告)日：2016-11-03
申请号：PCT/IL2016/050433
申请日：2016-04-21
申请人： VALTECH CARDIO LTD.
发明人： IFLAH, Ehud , REICH, Tal , SHEPS, Tal , HARITON, Ilia , BRAUON, Haim , KUTZIK, Meir , KOIFMAN, Alexei , HERMAN, Yaron
IPC分类号： A61F2/24 , A61B17/04
CPC分类号： A61F2/2445 , A61B17/0401 , A61F2/2412 , A61F2/2466 , A61F2250/0004 , A61F2250/001
摘要： Apparatus is provided including an implant including an annuloplasty structure (222, 611, 631, 641, 651, 711) having a primary body portion (750), a contraction member (226) extending along a contracting portion of the annuloplasty structure (222, 611, 631, 641, 651, 711), an actuatable adjustment mechanism (40) coupled to the contraction member, and, that when actuated, adjusts a length of the annuloplasty structure (222, 611, 631, 641, 651, 711) by applying tension to the contraction member (226), and a contraction-member-protecting element (633), having a first end coupled to the primary body portion (750) of the annuloplasty structure (222, 611, 631, 641, 651, 711), and a second end coupled to the adjustment mechanism (40). The contraction member (226) extends from the adjustment mechanism (40) via the contraction-member-protecting element (633) to the primary body portion (750) of the annuloplasty structure (222, 611, 631, 641, 651, 711). Other applications are also described.
摘要翻译：提供了包括植入物的装置，所述植入物包括具有主体部分（750）的瓣膜成形术结构（222,611,631,641,671,711），沿着所述瓣膜成形术结构（222）的收缩部分延伸的收缩构件（226）耦合到所述收缩构件的致动调节机构（40），以及当被致动时调节所述瓣环成形术结构（222,611,631,641,651,671,711）的长度，通过向收缩构件（226）施加张力，以及收缩构件保护元件（633），其具有联接到瓣环成形术结构（222,611,631,641,651）的主体部分（750）的第一端，711），以及联接到调节机构（40）的第二端。收缩构件（226）从调节机构（40）经由收缩构件保护元件（633）延伸到瓣环成形术结构（222,611,631,641,671,711）的主体部分（750）。还描述了其它应用。

5. 发明申请

WO2015059699A2 ANCHOR MAGAZINE 审中-公开
标题翻译：锚杆杂志
公开(公告)号：WO2015059699A2
公开(公告)日：2015-04-30
申请号：PCT/IL2014050914
申请日：2014-10-21
申请人： VALTECH CARDIO LTD
发明人： ZIPORY YUVAL , KOIFMAN ALEXEI , IFLAH EHUD , REICH TAL
IPC分类号： A61B17/04
CPC分类号： A61B17/105 , A61B17/068 , A61B50/20 , A61B50/30 , A61B2017/00243 , A61B2017/0053 , A61B2017/0416 , A61B2017/0649 , A61B2017/0688
摘要： Apparatus is provided, the apparatus comprising (i) a housing (22, 222), shaped to define a channel (24, 224) having an anchor-storage zone (26, 226) and an opening (28, 228) configured to provide access for an anchor driver (60) to the anchor-storage zone; (ii) a tissue anchor (40), stored in the anchor-storage zone and slidable through the channel; and (iii) a retaining member (30, 230). The retaining member (a) has a retaining state in which the retaining member is configured to retain the tissue anchor in the anchor-storage zone, and (b) is configured, by moving in response to a proximally-directed force applied to the tissue anchor, to allow the tissue anchor to leave the anchor-storage zone in response to the proximally-directed force. The proximally-directed force is greater than a pre-determined threshold force. Other embodiments are described.
摘要翻译：提供了一种设备，该设备包括：（i）外壳（22,222），其形状设置成具有锚固储存区（26,226）的通道（24,224）和设置成提供锚固器驱动器（60）进入锚固储存区域; （ii）组织锚固件（40），其存储在所述锚定储存区域中并可滑动通过所述通道; 和（iii）保持构件（30,230）。保持构件（a）具有保持状态，其中保持构件被构造成将组织锚固体保持在锚定储存区域中，并且（b）通过响应于施加到组织的向近侧方向的力而移动锚杆，以允许组织锚固件响应于向近侧方向的力离开锚固储存区域。近端方向的力大于预定阈值力。描述其他实施例。

6. 发明申请

WO2014064695A2 PERCUTANEOUS TISSUE ANCHOR TECHNIQUES 审中-公开
标题翻译： PERCUTANEOUS组织锚固技术
公开(公告)号：WO2014064695A2
公开(公告)日：2014-05-01
申请号：PCT/IL2013050861
申请日：2013-10-23
申请人： VALTECH CARDIO LTD
发明人： HERMAN YARON , ZIPORY YUVAL , STAROBINSKY SLAVA , REICH TAL , IFLAH EHUD , KOIFMAN ALEXEI
IPC分类号： A61M25/04
CPC分类号： A61B17/12009 , A61B17/0401 , A61B2017/00477 , A61B2017/00681 , A61B2017/0409 , A61B2017/0411 , A61B2017/0441 , A61B2017/0464 , A61B2017/0496 , A61B2017/2937 , A61F2/2445
摘要： A first element (91) includes a first arm (92) and a second arm coupled thereto and having a concavity (103) facing the first arm and defining a space (96). In an open state, a tissue anchor portion (46) moves into the space through a gap between distal portions (94) of the first and second arms. In the closed state, the anchor portion is not movable through the gap. A second element (82) is movable with respect to the first element, such that, while the portion (46) of the anchor (40) is within the space, and the first element is in the closed state, in a first position of the second element, the portion of the anchor is movable within the space, and in a second position of the second element, the second element applies torque to the anchor by rotating the second element. Other embodiments are also described.
摘要翻译：第一元件（91）包括第一臂（92）和与其连接的第二臂，并且具有面向第一臂并且限定空间（96）的凹部（103）。在打开状态下，组织锚定部分（46）通过第一和第二臂的远端部分（94）之间的间隙移动到空间中。在关闭状态下，锚固部分不能通过间隙移动。第二元件（82）可相对于第一元件移动，使得当锚（40）的部分（46）在空间内并且第一元件处于关闭状态时，在第一元件所述第二元件，所述锚固件的所述部分在所述空间内是可移动的，并且在所述第二元件的第二位置中，所述第二元件通过旋转所述第二元件而将扭矩施加到所述锚固件。还描述了其它实施例。

7. 发明申请

WO2012176195A3 CLOSURE ELEMENT FOR USE WITH ANNULOPLASTY STRUCTURE 审中-公开
公开(公告)号：WO2012176195A3
公开(公告)日：2012-12-27
申请号：PCT/IL2012/000250
申请日：2012-06-21
申请人： VALTECH CARDIO, LTD. , GROSS, Amir , SHEPS, Tal , HAMMER, Tal , REICH, Tal , IFLAH, Ehud , HERMAN, Yaron , POMERANTZ, Uriel, Aba , CABIRI, Oz
发明人： GROSS, Amir , SHEPS, Tal , HAMMER, Tal , REICH, Tal , IFLAH, Ehud , HERMAN, Yaron , POMERANTZ, Uriel, Aba , CABIRI, Oz
IPC分类号： A61F2/24
摘要： Apparatus is provided including an implantable structure (22), including a flexible sleeve (26), having first and second sleeve ends (49, 51), a contracting assembly (40), which is configured to longitudinally contract the sleeve (26). The contracting assembly (40) includes a contracting mechanism (28), which is at a first site of the sleeve (26); and a longitudinal contracting member (30), having (a) a first member end, (b) a second member end (53), coupled to the sleeve (26) at a second site longitudinally between the first site and the second sleeve end (49 or 51), exclusive. A force -distributing element (540) is couplable to the sleeve (26) in a vicinity of the second sleeve end (49 or 51), element (540) is configured to distribute a contraction force by the contracting member (30) between the second member end (53) and the second sleeve end (49 or 51). Other applications are also described.

8. 发明申请

WO2012014201A3 MULTIPLE ANCHOR DELIVERY TOOL 审中-公开
公开(公告)号：WO2012014201A3
公开(公告)日：2012-02-02
申请号：PCT/IL2011/000600
申请日：2011-07-26
申请人： VALTECH CARDIO, LTD. , CABIRI, Oz , GROSS, Amir , HAMMER, Tal , REICH, Tal , IFLAH, Ehud
发明人： CABIRI, Oz , GROSS, Amir , HAMMER, Tal , REICH, Tal , IFLAH, Ehud
IPC分类号： A61B17/04
摘要： An anchor deployment tool (30) includes a flexible outer tube (34), within which is positioned a flexible inner shaft (36), and a rotating deployment element (38) coupled to a distal end (39) of the shaft. The tool (30) is configured to provide an anchor storage area (40), which initially stores a plurality of tissue anchors (32), such that the inner shaft (36) passes through channels of the anchors along entire longitudinal lengths of the anchors (32), and the anchors are within the outer tube (34). The rotating deployment element (38) is configured to directly engage the anchors (32) in the anchor storage area (40) one at a time, advance each of the anchors while engaged in a distal direction, and deploy each of the anchors through the distal tube end (42) and into tissue of a subject. Other embodiments are also described.

9. 发明申请

WO2021140398A2 CATHETER ULTRASOUND DEVICES AND METHODS FOR ASSESSING TARGETED TISSUE 审中-公开
公开(公告)号：WO2021140398A2
公开(公告)日：2021-07-15
申请号：PCT/IB2020/062287
申请日：2020-12-21
申请人： VALTECH CARDIO, LTD.
发明人： SHARON, Assaf , KEIDAR, Yaron , GALON, Aviv , SHEPS, Tal , HERMAN, Yaron
IPC分类号： A61B17/04 , A61F2/24 , A61B8/12 , A61B34/20 , A61B17/0401 , A61B2017/00106 , A61B2017/00243 , A61B2017/0409 , A61B2017/0441 , A61B2034/2051 , A61B2034/2063 , A61B2090/3782 , A61B2090/3966 , A61B8/0841 , A61B8/0883 , A61B8/445 , A61B8/461 , A61B8/5223 , A61F2/2445 , A61F2/2466 , A61F2220/0016 , A61N1/05
摘要： An implant (20) comprises a wall (28) that surrounds a lumen (44). A delivery tool (8) comprises a catheter (22), a control assembly (64), and an ultrasound tool (36). The catheter is transluminally advanceable into a subject, and has a distal opening. The implant can be delivered via the catheter. The control assembly can advance at least a portion (70) of the wall out of the distal opening, and can steer the catheter to place the portion against a site of a tissue of the subject, the site disposed distally from the portion and opposite the distal opening. The ultrasound tool can (i) position an ultrasound transceiver within the lumen and facing the portion, and (ii) facilitate imaging of the site by transmitting ultrasound energy through the portion. An anchor driver can anchor the implant to the tissue by driving an anchor through the portion and into the site.

10. 发明申请

WO2020012481A3 ANNULOPLASTY SYSTEMS AND LOCKING TOOLS THEREFOR 审中-公开
公开(公告)号：WO2020012481A3
公开(公告)日：2020-01-16
申请号：PCT/IL2019/050777
申请日：2019-07-11
申请人： VALTECH CARDIO, LTD.
发明人： BRAUON, Haim , SHEPS, Tal , PINTOR, Rafael , GALON, Aviv
IPC分类号： A61F2/24
摘要： Apparatus is provided including an implantable annul oplasty structure (1152) including a primary body portion and a contracting member (226). A contracting-member- fastener (1560) can surround the contracting member and include a clamping structure that is biased toward assuming a closed state to clamp onto the contracting member passed therethrough. A stop (1570) can be removably coupled to the fastener and maintain the fastener in an open state. A contracting-member-uptake tool (1502) can include static and dynamic cutting elements (1510, 1520) and graspers (1505) configured to pull the stop proximally such that the stop pushes against and moves the dynamic cutting element with respect to the static cutting element in order to facilitate severing of the contracting member. Other applications are also provided.

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