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1. 发明申请

WO2012176195A3 CLOSURE ELEMENT FOR USE WITH ANNULOPLASTY STRUCTURE 审中-公开
公开(公告)号：WO2012176195A3
公开(公告)日：2012-12-27
申请号：PCT/IL2012/000250
申请日：2012-06-21
申请人： VALTECH CARDIO, LTD. , GROSS, Amir , SHEPS, Tal , HAMMER, Tal , REICH, Tal , IFLAH, Ehud , HERMAN, Yaron , POMERANTZ, Uriel, Aba , CABIRI, Oz
发明人： GROSS, Amir , SHEPS, Tal , HAMMER, Tal , REICH, Tal , IFLAH, Ehud , HERMAN, Yaron , POMERANTZ, Uriel, Aba , CABIRI, Oz
IPC分类号： A61F2/24
摘要： Apparatus is provided including an implantable structure (22), including a flexible sleeve (26), having first and second sleeve ends (49, 51), a contracting assembly (40), which is configured to longitudinally contract the sleeve (26). The contracting assembly (40) includes a contracting mechanism (28), which is at a first site of the sleeve (26); and a longitudinal contracting member (30), having (a) a first member end, (b) a second member end (53), coupled to the sleeve (26) at a second site longitudinally between the first site and the second sleeve end (49 or 51), exclusive. A force -distributing element (540) is couplable to the sleeve (26) in a vicinity of the second sleeve end (49 or 51), element (540) is configured to distribute a contraction force by the contracting member (30) between the second member end (53) and the second sleeve end (49 or 51). Other applications are also described.

2. 发明申请

WO2012014201A3 MULTIPLE ANCHOR DELIVERY TOOL 审中-公开
公开(公告)号：WO2012014201A3
公开(公告)日：2012-02-02
申请号：PCT/IL2011/000600
申请日：2011-07-26
申请人： VALTECH CARDIO, LTD. , CABIRI, Oz , GROSS, Amir , HAMMER, Tal , REICH, Tal , IFLAH, Ehud
发明人： CABIRI, Oz , GROSS, Amir , HAMMER, Tal , REICH, Tal , IFLAH, Ehud
IPC分类号： A61B17/04
摘要： An anchor deployment tool (30) includes a flexible outer tube (34), within which is positioned a flexible inner shaft (36), and a rotating deployment element (38) coupled to a distal end (39) of the shaft. The tool (30) is configured to provide an anchor storage area (40), which initially stores a plurality of tissue anchors (32), such that the inner shaft (36) passes through channels of the anchors along entire longitudinal lengths of the anchors (32), and the anchors are within the outer tube (34). The rotating deployment element (38) is configured to directly engage the anchors (32) in the anchor storage area (40) one at a time, advance each of the anchors while engaged in a distal direction, and deploy each of the anchors through the distal tube end (42) and into tissue of a subject. Other embodiments are also described.

3. 发明申请

WO2013069019A2 CONTROLLED STEERING FUNCTIONALITY FOR IMPLANT-DELIVERY TOOL 审中-公开
标题翻译：用于植入式工具的控制转向功能
公开(公告)号：WO2013069019A2
公开(公告)日：2013-05-16
申请号：PCT/IL2012/050451
申请日：2012-11-08
申请人： VALTECH CARDIO, LTD. , SHEPS, Tal , HAMMER, Tal , IFLAH, Ehud , REICH, Tal , HERMAN, Yaron , GROSS , Amir
发明人： SHEPS, Tal , HAMMER, Tal , IFLAH, Ehud , REICH, Tal , HERMAN, Yaron , GROSS , Amir
IPC分类号： A61B1/01
CPC分类号： A61F2/2427 , A61B17/068 , A61B17/105 , A61B2017/00305 , A61B2017/00314 , A61B2017/00323 , A61B2017/00367 , A61B2017/0649 , A61B2017/293 , A61B2090/0811 , A61F2/2445 , A61F2/2466 , A61F2210/0014 , A61F2250/001 , A61F2250/0098 , A61M25/005 , A61M25/0054 , A61M25/0068 , A61M25/01 , A61M25/0105 , A61M25/0108 , A61M25/0133 , A61M25/0136 , A61M25/0147 , A61M25/0662 , A61M2025/0004 , A61M2025/0006 , A61M2025/015 , A61M2025/0681
摘要： Apparatus for percutaneous access to a patient's body comprising a first steerable tube (12), shaped to define a first lumen, and a first coupling (152) at a longitudinal site of the first tube; and a second steerable tube (14), shaped to define a second lumen and a second coupling (154), the second coupling being intracorporeally couplable to the first coupling, the apparatus having (A) an unlocked state in which the second tube is rotatable within the first lumen, and (B) a locked state in which the second coupling is coupled to the first coupling, and rotation of the second tube is inhibited. The apparatus is configured such that when the second coupling becomes disposed at the longitudinal site in a given rotational orientation of the second tube, the apparatus moves into the locked state by the second coupling automatically coupling to the first coupling. Other embodiments are also described.
摘要翻译：用于经皮进入患者身体的装置，包括成形为限定第一内腔的第一可转向管（12）和在所述第一管的纵向位置处的第一联接器（152）; 以及第二可转向管（14），其被成形为限定第二内腔和第二联接器（154），所述第二联接器与所述第一联接件体内联接，所述设备具有（A）第二管可旋转的解锁状态在第一管腔内，和（B）第二联接器联接到第一联接器的锁定状态，并且禁止第二管的旋转。该装置被构造成使得当第二联接器以第二管的给定旋转方向设置在纵向位置时，该装置通过自动联接到第一联接器的第二联接器移动到锁定状态。还描述了其它实施例。

4. 发明申请

WO2011154942A2 APPARATUS AND METHOD FOR GUIDE-WIRE BASED ADVANCEMENT OF A ROTATION ASSEMBLY 审中-公开
标题翻译：用于基于引导线的旋转组件优化的装置和方法
公开(公告)号：WO2011154942A2
公开(公告)日：2011-12-15
申请号：PCT/IL2011/000446
申请日：2011-06-06
申请人： VALTECH CARDIO, LTD. , MILLER, Eran , CABIRI, Oz , REICH, Tal , SHEPS, Tal
发明人： MILLER, Eran , CABIRI, Oz , REICH, Tal , SHEPS, Tal
IPC分类号： A61F2/24
CPC分类号： A61F2/2457 , A61B17/0401 , A61B2017/00243 , A61B2017/0441 , A61B2017/0448 , A61B2017/0464 , A61B2017/0496 , A61F2/2466
摘要： Apparatus is provided for use with at least one implant (42), including a tissue-engaging element having a distal portion configured to engage at least a first portion of tissue of a patient, and having a proximal portion. At least one docking station (56) is coupled to the proximal portion of the tissue-engaging element and is configured to be coupled to the at least one implant (42). The docking station (56) includes a locking mechanism (57) configured to lock the implant (42) to the tissue-engaging element. At least one guide member (40) is reversibly coupled to the at least one docking station (56) and is configured for facilitating slidable advancement of the at least one implant (42) toward the tissue-engaging element. Other applications are also described.
摘要翻译：提供了用于与至少一个植入物（42）一起使用的装置，包括组织接合元件，所述组织接合元件具有构造成与患者的组织的至少第一部分接合并具有近端部分的远侧部分。至少一个对接站（56）联接到组织接合元件的近端部分并且被配置为联接到至少一个植入物（42）。对接站（56）包括锁定机构（57），其构造成将植入物（42）锁定到组织接合元件。至少一个引导构件（40）可逆地联接到所述至少一个对接站（56），并且被构造成便于使所述至少一个植入物（42）朝向所述组织接合元件的可滑动前进。还描述了其它应用。

5. 发明申请

WO2016059639A1 LEAFLET-RESTRAINING TECHNIQUES 审中-公开
标题翻译：叶片限制技术
公开(公告)号：WO2016059639A1
公开(公告)日：2016-04-21
申请号：PCT/IL2015/051027
申请日：2015-10-14
申请人： VALTECH CARDIO LTD.
发明人： GROSS, Amir , REICH, Tal , HERMAN, Yaron , IFLAH, Ehud , BRAUON, Haim , KUTZIK, Meir , IAMBERGER, Meni
IPC分类号： A61F2/24
CPC分类号： A61F2/2454 , A61B17/068 , A61B2017/00292 , A61B2017/0647 , A61B2017/0649 , A61F2/2445 , A61F2/2451 , A61F2/2457 , A61F2/2466 , A61F2220/0016
摘要： Apparatus, comprising: (i) a catheter (64); (ii) an implant (100), comprising a flexible longitudinal member (102), and a linking member (104) that extends from a first linking site (106a) of the longitudinal member to a second linking site (106b) of the longitudinal member, the implant having: (a) a delivery state in which the longitudinal member is coaxial with the catheter, and at least a portion of the linking member is disposed alongside the longitudinal member, and (b) an implanted state in which a first distance between the first linking site and the second linking site, measured along the longitudinal member, is greater than a second distance between the first linking site and the second linking site, measured along the linking member; and (iii) a plurality of tissue anchors (46), slidable through the catheter and with respect to the longitudinal member. Other embodiments are also described.
摘要翻译：装置，包括：（i）导管（64）; （ii）包括柔性纵向构件（102）的植入物（100）和从所述纵向构件的第一连接位置（106a）延伸到所述纵向构件（102）的第二连接位置（106b）的连接构件（104）所述植入物具有：（a）所述纵向构件与所述导管同轴的输送状态，并且所述连接构件的至少一部分与所述纵向构件一起设置，以及（b）植入状态，其中第一沿着纵向构件测量的第一连接位点和第二连接位点之间的距离大于沿着连接构件测量的第一连接位点和第二连接位点之间的第二距离; 和（iii）可以穿过导管并相对于纵向构件滑动的多个组织锚固件（46）。还描述了其它实施例。

6. 发明申请

WO2014064695A3 PERCUTANEOUS TISSUE ANCHOR TECHNIQUES 审中-公开
公开(公告)号：WO2014064695A3
公开(公告)日：2014-05-01
申请号：PCT/IL2013/050861
申请日：2013-10-23
申请人： VALTECH CARDIO, LTD.
发明人： HERMAN, Yaron , ZIPORY, Yuval , STAROBINSKY, Slava , REICH, Tal , IFLAH, Ehud , KOIFMAN, Alexei
IPC分类号： A61B17/04
摘要： A first element (91) includes a first arm (92) and a second arm coupled thereto and having a concavity (103) facing the first arm and defining a space (96). In an open state, a tissue anchor portion (46) moves into the space through a gap between distal portions (94) of the first and second arms. In the closed state, the anchor portion is not movable through the gap. A second element (82) is movable with respect to the first element, such that, while the portion (46) of the anchor (40) is within the space, and the first element is in the closed state, in a first position of the second element, the portion of the anchor is movable within the space, and in a second position of the second element, the second element applies torque to the anchor by rotating the second element. Other embodiments are also described.

7. 发明申请

WO2020240282A2 TISSUE ANCHOR HANDLING SYSTEMS AND METHODS 审中-公开
公开(公告)号：WO2020240282A2
公开(公告)日：2020-12-03
申请号：PCT/IB2020/000472
申请日：2020-05-08
申请人： VALTECH CARDIO, LTD.
发明人： BRAUON, Haim , AVIV, Ehud , MURPHY, Brian Patrick , DE SILVA, Praveen , DANG, Kevin K. , AZANKI, Omar Fawzi , GOLAN, Tomer , NESS, Aaron Anan , REICH, Tal , MOLINA, Luis , SHAFIGH, Sam
IPC分类号： A61B17/04 , A61B50/30 , A61B50/20 , A61B90/53
摘要： An apparatus is provided for use with an anchor-handling device (20). The apparatus includes a holder (90) shaped to define a space (92) for receiving the anchor-handling device (20). The holder (90) includes a coupling (94) configured to reversibly couple the anchor- handling device (20) to the holder (94). The apparatus also includes a wearable article (100) coupled to the holder (90). The wearable article (100) is configured to temporarily affix the anchor-handling device (20) to a body of an operating physician that is using the anchor-handling device (20). Other applications are also described.

8. 发明申请

WO2019145941A1 TECHNIQUES FOR FACILITATING HEART VALVE TETHERING AND CHORD REPLACEMENT 审中-公开
公开(公告)号：WO2019145941A1
公开(公告)日：2019-08-01
申请号：PCT/IL2019/050083
申请日：2019-01-22
申请人： VALTECH CARDIO, LTD.
发明人： REICH, Tal
IPC分类号： A61F2/24 , A61B5/107 , A61B17/04 , A61B17/00 , A61B17/122 , A61B90/00
CPC分类号： A61F2/2457 , A61B5/1076 , A61B6/487 , A61B17/0401 , A61B17/122 , A61B2017/00243 , A61B2017/00783 , A61B2017/0409 , A61B2017/0441 , A61B2017/0464 , A61B2090/061 , A61B2090/3966 , A61F2/2466 , A61F2/2496
摘要： A method is described, for use with a native valve (10) of a heart (4) of a subject, the valve being disposed between an atrium (6) and a ventricle (8) of the heart. A first radiopaque marker (32) and a second radiopaque marker (34) are percutaneously advanced to the heart. The first radiopaque marker is placed against a tissue site (42) in the ventricle. The second radiopaque marker is placed against a leaflet (12) of the valve. A distance is measured between the first radiopaque marker at the tissue site, and the second radiopaque marker at the leaflet. Responsively to the measured distance, a chord-length is determined. An artificial chord (60), selected based on the chord-length, is implanted in the heart. Other embodiments are also described.

9. 发明申请

WO2016174669A1 ANNULOPLASTY TECHNOLOGIES 审中-公开
标题翻译： ANNULOPLASTY技术
公开(公告)号：WO2016174669A1
公开(公告)日：2016-11-03
申请号：PCT/IL2016/050433
申请日：2016-04-21
申请人： VALTECH CARDIO LTD.
发明人： IFLAH, Ehud , REICH, Tal , SHEPS, Tal , HARITON, Ilia , BRAUON, Haim , KUTZIK, Meir , KOIFMAN, Alexei , HERMAN, Yaron
IPC分类号： A61F2/24 , A61B17/04
CPC分类号： A61F2/2445 , A61B17/0401 , A61F2/2412 , A61F2/2466 , A61F2250/0004 , A61F2250/001
摘要： Apparatus is provided including an implant including an annuloplasty structure (222, 611, 631, 641, 651, 711) having a primary body portion (750), a contraction member (226) extending along a contracting portion of the annuloplasty structure (222, 611, 631, 641, 651, 711), an actuatable adjustment mechanism (40) coupled to the contraction member, and, that when actuated, adjusts a length of the annuloplasty structure (222, 611, 631, 641, 651, 711) by applying tension to the contraction member (226), and a contraction-member-protecting element (633), having a first end coupled to the primary body portion (750) of the annuloplasty structure (222, 611, 631, 641, 651, 711), and a second end coupled to the adjustment mechanism (40). The contraction member (226) extends from the adjustment mechanism (40) via the contraction-member-protecting element (633) to the primary body portion (750) of the annuloplasty structure (222, 611, 631, 641, 651, 711). Other applications are also described.
摘要翻译：提供了包括植入物的装置，所述植入物包括具有主体部分（750）的瓣膜成形术结构（222,611,631,641,671,711），沿着所述瓣膜成形术结构（222）的收缩部分延伸的收缩构件（226）耦合到所述收缩构件的致动调节机构（40），以及当被致动时调节所述瓣环成形术结构（222,611,631,641,651,671,711）的长度，通过向收缩构件（226）施加张力，以及收缩构件保护元件（633），其具有联接到瓣环成形术结构（222,611,631,641,651）的主体部分（750）的第一端，711），以及联接到调节机构（40）的第二端。收缩构件（226）从调节机构（40）经由收缩构件保护元件（633）延伸到瓣环成形术结构（222,611,631,641,671,711）的主体部分（750）。还描述了其它应用。

10. 发明申请

WO2019224814A1 IMPLANTABLE ANNULOPLASTY STRUCTURES TO FIT MULTIPLE ANNULUS SIZES 审中-公开
公开(公告)号：WO2019224814A1
公开(公告)日：2019-11-28
申请号：PCT/IL2019/050569
申请日：2019-05-21
申请人： VALTECH CARDIO, LTD.
发明人： PELEG, Carmel , PEER, Amit , KUTZIK, Meir , FOGEL, Alon , AZOURI, Ben , BRAUON, Haim , CHAPPEL-RAM, Shlomit , REICH, Tal
IPC分类号： A61F2/24
摘要： An annuloplasty structure (122) includes a body portion (123) and a contracting member (30). The body portion can include flexible material and be shaped to define one or more controllably-expandable sections (40). Each of the controllably-expandable sections has a respective first length (Ll). Each of the controllably-expandable sections can be expanded or reduced to assume a respective second length (L2) that is different from the respective first length. The contracting member is coupled to the body portion, and is configured to contract the body portion independently of the mechanism that expands the controllably-expandable sections. Other embodiments are also described.

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