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1. 发明申请

WO2008063663A2 POLY (ETHYLENE GLYCOL) ANTI-BODY DETECTION ASSAYS AND KITS FOR PERFORMING THEREOF 审中-公开
标题翻译：聚乙二醇（乙烯甘油）抗体检测试剂及其用于实施的试剂
公开(公告)号：WO2008063663A2
公开(公告)日：2008-05-29
申请号：PCT/US2007/024349
申请日：2007-11-20
申请人： UNIVERSITY OF SOUTHERN CALIFORNIA USC STEVENS , ARMSTRONG, Jonathan, K. , FISHER, Timothy
发明人： ARMSTRONG, Jonathan, K. , FISHER, Timothy
IPC分类号： G01N33/53 , G01N33/542 , G01N33/00 , G01N33/543
CPC分类号： G01N33/6854 , G01N2800/52
摘要： The present invention discloses an assay for determining the presence of an anti-PEG antibody in a biological sample. Embodiments according to this aspect of the present invention will generally have the steps of: (1) providing an antigen probe capable of forming an antibody- antigen complex with the anti-PEG antibody; (2) contacting the biological sample with the antigen probe under conditions favorable for formation of the antibody-antigen complex; and (3) analyzing the antigen probe, after having performed step (2), to detect for the presence of the antibody-antigen complex, wherein the presence of the anti-PEG antibody is determined if the antibody-antigen complex is detected. Also disclosed are methods for screening patients, methods for monitoring patients using assays of this invention and kits for performing thereof.
摘要翻译：本发明公开了一种测定生物样品中抗-PEG抗体的存在的方法。根据本发明该方面的实施方案通常具有以下步骤：（1）提供能够与抗-PEG抗体形成抗体 - 抗原复合物的抗原探针; （2）在有利于形成抗体 - 抗原复合物的条件下，使生物样品与抗原探针接触; 和（3）在进行了步骤（2）之后分析抗原探针以检测抗体 - 抗原复合物的存在，其中如果检测到抗体 - 抗原复合物，则测定抗-PEG抗体的存在。还公开了用于筛选患者的方法，使用本发明测定法监测患者的方法以及用于进行本发明的试剂盒。

2. 发明申请

WO2004072491A2 UNIVERSAL JOINT ADAPTER RING 审中-公开
标题翻译：通用接头适配器环
公开(公告)号：WO2004072491A2
公开(公告)日：2004-08-26
申请号：PCT/US2004/003471
申请日：2004-02-06
申请人： BIGELOW GROUP , HOFFMAN, Marvin , BIGELOW, Vaughn , FISHER, Timothy
发明人： HOFFMAN, Marvin , BIGELOW, Vaughn , FISHER, Timothy
IPC分类号： F16B
CPC分类号： F16D3/43 , Y10S464/905
摘要： The present invention relates to a ring member (10) of a ring-type universal joint (100) utilized for transferring rotary motion from a first shaft (102) to a second shaft (104). The ring member (10) includes a plurality of circumferentially spaced openings (12) for receiving outwardly extending torque transfer elements (32, 42) associated with the first and second shafts (102, 104). One or more of these openings (12) are separable to facilitate connection of the first and second shafts (102, 104). In this regard, the separable bores (12) are formed partially within the ring member (10) and partially within a retaining member (20) interconnectable to the ring member (10). This allows for disposing a torque transfer element within a portion of the bore (12) formed on the ring member (10) and then interconnecting the retainer (20) over that element. In one embodiment, the retaining members (20) for first and second opposing pairs of bores (12) interconnect to opposite sides of the ring member (10) allowing individual interconnection of the shafts (102, 104) to the ring (10).
摘要翻译：本发明涉及一种用于将旋转运动从第一轴（102）转移到第二轴（104）的环形万向接头（100）的环形构件（10）。环构件（10）包括多个周向间隔开的开口（12），用于接收与第一和第二轴（102,104）相关联的向外延伸的扭矩传递元件（32,42）。这些开口（12）中的一个或多个可分离以便于连接第一和第二轴（102,104）。在这方面，可分离的孔（12）部分地形成在环形构件（10）内并且部分地形成在与环形构件（10）可互连的保持构件（20）内。这允许将扭矩传递元件设置在形成在环形构件（10）上的孔（12）的一部分内，然后将保持器（20）与该元件相互连接。在一个实施例中，用于第一和第二相对的孔对（12）的保持构件（20）互连到环构件（10）的相对侧，允许轴（102,104）与环（10）的单独互连。

3. 发明申请

WO2004088699A2 UNIVERSAL JOINT YOKE ADAPTER 审中-公开
标题翻译：通用接头适配器
公开(公告)号：WO2004088699A2
公开(公告)日：2004-10-14
申请号：PCT/US2004/009139
申请日：2004-03-25
申请人： BIGELOW GROUP , FISHER, Timothy , HOFFMAN, Marvin
发明人： FISHER, Timothy , HOFFMAN, Marvin
IPC分类号： H01J
CPC分类号： F16D3/42 , F16D3/38 , F16D3/40
摘要： The present invention is directed to an adapter for converting a yoke, which was originally designed to receive a torque transfer element between opposing surfaces, into a yoke designed to be received with an annular member of a ring-type universal joint. In this regard, cruciform-type universal joints may be readily replaced with ring-type universal joints. In a first embodiment, the adapter provides a first interface surface for engaging a yoke member that at least partially defines first and second opposing radial bores and a second interface surface for pivotal interconnection within an aperture of a ring-type universal joint. The first and second interface surfaces may be formed in multiple sizes to allow variously formed yoke members to be converted for use with a ring-type universal joint.
摘要翻译：本发明涉及一种用于转换最初被设计成在相对表面之间接收转矩传递元件的轭的适配器，该轭被设计成与环形万向接头的环形构件接收。在这方面，十字形万向接头可以容易地被环形万向节替代。在第一实施例中，适配器提供用于接合至少部分地限定第一和第二相对的径向孔的轭构件的第一界面表面和用于在环型万向接头的孔内枢转互连的第二界面表面。第一和第二界面可以形成多个尺寸以允许各种形式的轭构件转换为与环型万向接头一起使用。

4. 发明申请

WO2002084155A1 CONTROL VALVE MONITORING 审中-公开
标题翻译：控制阀监控
公开(公告)号：WO2002084155A1
公开(公告)日：2002-10-24
申请号：PCT/AU2002/000448
申请日：2002-04-10
申请人： SMART FLOW PTY LTD , SHEERAN, Howard, Stephen , WATTS, Jeffrey, James , BULLEN, Christopher, Joachim , MILAN, Scott , DEGNAN, Paul , FISHER, Timothy
发明人： SHEERAN, Howard, Stephen , WATTS, Jeffrey, James , BULLEN, Christopher, Joachim , MILAN, Scott , DEGNAN, Paul , FISHER, Timothy
IPC分类号： F16K37/00
CPC分类号： G05D23/1393 , F16K37/0091 , Y10T137/8158 , Y10T137/8175
摘要： The present invention provides a device for monitoring the operation of a control valve (1), which is adapted to supply fluid at a predetermined temperature via an outlet (4). The device includes a sensor (10) adapted to be coupled to the outlet (4) so as to sense the temperature of the fluid. An indication device (16) and a processor (18) are provided. In use, the processor is adapted to determine the temperature of the fluid from the sensor and, provide an indication of this via the indication device.
摘要翻译：本发明提供了一种用于监测控制阀（1）的操作的装置，其适于经由出口（4）在预定温度下供应流体。该装置包括适于联接到出口（4）以便感测流体温度的传感器（10）。提供指示装置（16）和处理器（18）。在使用中，处理器适于确定来自传感器的流体的温度，并且经由指示装置提供其指示。

5. 发明申请

WO2013067472A1 REFRIGERATION FROM GRAPHENE-BASED NANOEMITTERS 审中-公开
标题翻译：从基于石墨的纳米级制冷
公开(公告)号：WO2013067472A1
公开(公告)日：2013-05-10
申请号：PCT/US2012/063480
申请日：2012-11-04
申请人： FISHER, Timothy , PURDUE RESEARCH FOUNDATION
发明人： FISHER, Timothy
IPC分类号： C01B31/02 , C01B31/04 , B01J19/12 , B01J19/24
CPC分类号： H01L31/0288 , B82Y30/00 , B82Y40/00 , C01B32/186 , C01B32/194 , C23C16/26 , C23C16/56
摘要： This disclosure presents the use of electrons as the 'working fluid' in conjunction with a solid nanomaterial that hinders electron coupling to the atomic lattice of the nanomaterial, i.e., they are out of equilibrium. The electrons can achieve very high effective temperatures with minimal heating of the solid lattice. These 'hot' electrons emit from the absorbing material, carrying both the light energy and energy acquired from the atomic lattice. Thus, the operation of this disclosure includes shining light on an object to make the object cool instead of heat. It is envisioned that one of ordinary skill in the art would find the operation quite counter-intuitive.
摘要翻译：本公开提供了电子作为“工作流体”与固体纳米材料结合使用，这阻碍了与纳米材料的原子晶格的电子耦合，即它们不平衡。电子可以实现非常高的有效温度，同时固体晶格的加热最小。这些“热”电子从吸收材料发射，同时携带从原子晶格获得的光能和能量。因此，本公开的操作包括将光照射在物体上以使物体变冷而不是加热。可以设想，本领域普通技术人员会发现操作非常直观。

6. 发明申请

WO2008016344A1 THERMIONIC EMITTING METAL INTERCALATED GRAPHITIC NANOFIBERS 审中-公开
标题翻译：发热金属介质金属纳米纤维
公开(公告)号：WO2008016344A1
公开(公告)日：2008-02-07
申请号：PCT/US2006/029539
申请日：2006-07-31
申请人： VANDERBILT UNIVERSITY , LUKEHART, Charles, M. , MICHEL, Jason, A. , FISHER, Timothy , ROBINSON, Vance
发明人： LUKEHART, Charles, M. , MICHEL, Jason, A. , FISHER, Timothy , ROBINSON, Vance
IPC分类号： B32B9/00 , B32B19/00
CPC分类号： C22C49/02 , C22C49/14
摘要： A carbon-based composition comprising graphite carbon nano-fibers intercalated with a metal useful as a thermionic electron emission material.
摘要翻译：一种碳基组合物，其包含插入有用作热电子发射材料的金属的石墨碳纳米纤维。

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