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1. 发明申请

WO03052514A9 PATTERNING OF SOLID STATE FEATURES BY DIRECT WRITE NANOLITHOGRAPHIC PRINTING 审中-公开
标题翻译：直写纳米二氧化硅印刷固体特征图形
公开(公告)号：WO03052514A9
公开(公告)日：2004-06-03
申请号：PCT/US0240118
申请日：2002-12-17
申请人： UNIV NORTHWESTERN , MIRKIN CHAD A , DRAVID VINAYAK P , SU MING , LIU XIAOGANG
发明人： MIRKIN CHAD A , DRAVID VINAYAK P , SU MING , LIU XIAOGANG
IPC分类号： B82B3/00 , G03F7/00 , H01L21/027
CPC分类号： B82B3/00 , B82Y10/00 , B82Y30/00 , B82Y40/00 , G03F7/0002 , Y10S977/855 , Y10S977/857 , Y10T428/24802 , Y10T428/24926 , Y10T428/265
摘要： The present invention includes a method of fabricating organic/inorganic composite nanostructures on a substrate comprising depositing a solution having a block copolymer and an inorganic precursor on the substrate using dip pen nanolithography. The nanostructures comprises arrays of lines and/or dots having widths/diameters less than 1 micron. The present invention also includes a device comprising an organic/inorganic composite nanoscale region, wherein the nanoscale region has a nanometer scale dimension other than height.
摘要翻译：本发明包括在基底上制造有机/无机复合纳米结构的方法，包括使用蘸水笔纳米平版印刷法在基底上沉积具有嵌段共聚物和无机前体的溶液。纳米结构包括宽度/直径小于1微米的线和/或点的阵列。本发明还包括包含有机/无机复合纳米尺度区域的装置，其中纳米尺度区域具有除高度之外的纳米尺度尺寸。

2. 发明申请

WO2008005375A3 KIDNEY TOXICITY BIOMARKERS 审中-公开
标题翻译： KIDNEY毒性生物标志物
公开(公告)号：WO2008005375A3
公开(公告)日：2008-10-23
申请号：PCT/US2007015202
申请日：2007-06-28
申请人： MERCK & CO INC , GERHOLD DAVID J , HOLDER DANIEL J , JIN HONG , FIGUEROA DAVID J , BAILEY WENDY J , OZER JOSEF S , SU MING
发明人： GERHOLD DAVID J , HOLDER DANIEL J , JIN HONG , FIGUEROA DAVID J , BAILEY WENDY J , OZER JOSEF S , SU MING
IPC分类号： C12Q1/68 , C07H21/02 , C07H21/04 , C07K14/435 , G01N33/53
CPC分类号： C12Q1/6883 , C12Q2600/142 , C12Q2600/158
摘要： Novel biomarkers for kidney toxicity. Said biomarkers may be useful for optimization of lead compounds, or in safety assessment.
摘要翻译：肾毒性的新型生物标志物。所述生物标志物可用于优化铅化合物或安全评估。

3. 发明申请

WO2007117377A2 METHOD AND APPARATUS FOR REMOTE SENSING OF MOLECULAR SPECIES AT NANOSCALE UTILIZING A REVERSE PHOTOACOUSTIC EFFECT 审中-公开
标题翻译：遥感遥感影像分析方法及装置在纳米光栅中的应用
公开(公告)号：WO2007117377A2
公开(公告)日：2007-10-18
申请号：PCT/US2007006206
申请日：2007-03-12
申请人： UT BATTELLE LLC , SU MING , THUNDAT THOMAS G , HEDDEN DAVID
发明人： SU MING , THUNDAT THOMAS G , HEDDEN DAVID
CPC分类号： G01N29/075 , G01N29/0681 , G01N29/2418 , G01N2291/012 , G01N2291/02466 , G01N2291/0423 , G01N2291/0427 , G01N2291/044 , G01N2291/048 , G01N2291/102
摘要： A method and apparatus for identifying a sample, involves illuminating the sample with light of varying wavelengths, transmitting an acoustic signal against the sample from one portion and receiving a resulting acoustic signal on another portion, detecting a change of phase in the acoustic signal corresponding to the light of varying wavelengths, and analyzing the change of phase in the acoustic signal for the varying wavelengths of illumination to identify the sample. The apparatus has a controlled source (67) for illuminating the sample with light of varying wavelengths, a transmitter (61, 63) for transmitting an acoustic wave, a detector (68, 69) for detecting the acoustic wave and converting the acoustic wave to an electronic signal, and an electronic circuit (62) for detecting a change of phase in the acoustic wave corresponding to respective ones of the varying wavelengths and output ting the change of phase for the varying wavelengths to allow identification of the sample. The method and apparatus can be used to detect chemical composition or visual features. A transmission mode and a reflection mode of operation are disclosed. The method and apparatus can be applied at nanoscale to detect molecules in a biological sample.
摘要翻译：用于识别样品的方法和装置包括用变化的波长的光照射样品，从一个部分发射针对样品的声信号，并在另一部分上接收所得到的声信号，检测对应的声信号中的相位变化改变波长的光，并分析用于变化的照明波长的声信号中的相位变化，以识别样品。该装置具有用于用波长不同的光照射样品的受控源（67），用于传输声波的发射器（61,63），用于检测声波并将声波转换成声波的检测器（68,69）一个电子信号和一个电子电路（62），用于检测对应于各个变化波长的声波相位的变化，并输出变化的波长的相位变化，以允许样本的识别。该方法和装置可用于检测化学成分或视觉特征。公开了传输模式和反射操作模式。该方法和装置可应用于纳米尺度以检测生物样品中的分子。

4. 发明申请

WO2005027199A3 NANODISK SENSOR AND SENSOR ARRAY 审中-公开
标题翻译： NANODISK传感器和传感器阵列
公开(公告)号：WO2005027199A3
公开(公告)日：2007-09-27
申请号：PCT/US2004004968
申请日：2004-02-18
申请人： UNIV NORTHWESTERN
发明人： SU MING , DRAVID VINAYAK P
IPC分类号： G01N7/00 , C23C18/12 , G01N27/12 , G01Q80/00
CPC分类号： G01N27/128 , G01Q80/00
摘要： The invention provides a sensor array with different nanodisk sensors that may be fabricated by direct site-specific dip-pen nanopatterning (DPN) using precursor inks. The good flow characteristics and strong affinity of the sols to measurement electrodes enable intimate ohmic contact. The measurable, reproducible and proportionate changes in the resistance of the sensors when exposed to trace quantities of oxidative and reducing gases constitute the basis for nanodisk gas sensors. The nanodisk sensors show rapid response and ultra-fast recovery for the detection of nitrogen dioxide and acetic acid vapor. Based on the principles of pattern recognition of the olfactory system, an electronic nose that can "smell" different gaseous species is provided with the multiple nanodisk sensor array. These nanodisk sensors have gas recognition ability, instant response and rapid recovery, compact size and integration with the established microelectronics platform and are wellsuited for the on-site and real-time detection of gases.
摘要翻译：本发明提供了具有不同纳米盘传感器的传感器阵列，其可以通过使用前体油墨的直接位置特异性浸渍笔纳米图案（DPN）来制造。溶胶对测量电极的良好流动特性和强亲合力使得能够进行紧密的欧姆接触。当暴露于微量的氧化还原气体时，传感器电阻的可测量，可重现和成比例的变化构成了纳米盘气体传感器的基础。纳米盘传感器显示快速响应和超快速恢复，用于检测二氧化氮和乙酸蒸气。基于嗅觉系统的模式识别原理，提供了可以“闻到”不同气态物种的电子鼻子，其具有多纳米盘传感器阵列。这些纳米盘传感器具有气体识别能力，即时响应和快速恢复，紧凑的尺寸和与已建立的微电子平台的集成，并且用于气体的现场和实时检测。

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