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1. 发明申请

WO2016053954A1 RIGID NEEDLE INSERTION MECHANISM FOR A DRUG DELIVERY PUMP 审中-公开
标题翻译：用于药液输送泵的刚性针插入机构
公开(公告)号：WO2016053954A1
公开(公告)日：2016-04-07
申请号：PCT/US2015/052815
申请日：2015-09-29
申请人： UNITRACT SYRINGE PTY LTD , DESTEFANO, Mark
发明人： DESTEFANO, Mark , HANSON, Ian , BENTE, Paul , LAURENCE, Lawton
IPC分类号： A61M5/158 , A61M5/142
CPC分类号： A61M5/158 , A61M5/142 , A61M5/14248 , A61M2005/14252 , A61M2005/14256 , A61M2005/1585
摘要： An insertion mechanism (200) and methods of assembly and operation of a drug pump (10) may include an insertion mechanism housing (202); a housing cap; a manifold guide (220); an insertion biasing member (210) initially held in an energized state; a retraction biasing member (216) connected to a hub (212) connected to a proximal end of a needle (214); and, optionally, a clip retainer. The retraction biasing member is held initially in an energized state between the hub and manifold guide. A manifold has a manifold body and one or more septa defining a manifold header. The retraction biasing member may be held initially in an energized state between the hub and the clip retainer. The needle is advanced by the insertion biasing member(s) from the initial configuration to an administration configuration, opening a fluid pathway from the manifold header to the target. The drug delivery pump may include an activation mechanism, a drive mechanism, a fluid pathway connection, and the insertion mechanism.
摘要翻译：插入机构（200）以及药物泵（10）的组装和操作的方法可以包括插入机构壳体（202）; 房屋帽歧管引导件（220）; 最初保持在通电状态的插入偏置构件（210）连接到连接到针（214）的近端的轮毂（212）上的回缩偏置构件（216）; 和可选的夹子保持器。回缩偏压构件最初保持在轮毂和歧管引导件之间的通电状态。歧管具有歧管主体和限定歧管歧管的一个或多个隔片。回缩偏压构件可以初始地保持在轮毂和夹子保持器之间的通电状态。针通过插入偏置构件从初始构型推进到管理构型，打开从歧管歧管到目标的流体通道。药物输送泵可以包括激活机构，驱动机构，流体通路连接和插入机构。

2. 发明申请

WO2016049532A1 SEQUENTIAL CHAMBER DRUG DELIVERY PUMPS FOR DRUG MIXING AND DELIVERY 审中-公开
标题翻译：用于药物混合和递送的序列化学药物递送泵
公开(公告)号：WO2016049532A1
公开(公告)日：2016-03-31
申请号：PCT/US2015/052367
申请日：2015-09-25
申请人： UNITRACT SYRINGE PTY LTD , DAVENPORT, Daniel
发明人： DAVENPORT, Daniel , HANSON, Ian , WEAVER, Molly
IPC分类号： A61M5/315 , A61M5/142
CPC分类号： A61M5/31596 , A61M5/1422 , A61M5/315 , A61M2005/31598
摘要： The present disclosure provides drug containers that allow for the mixing of one or more substances prior to drug injection and drug delivery pumps incorporating such drug containers. Mixing of the two or more substances contained within separate, mutable chambers (64)(66) is initiated by transforming a seal assembly from a closed position to an open position in which the mutable chambers are in fluid communication with one another. Continued mixing is induced by causing the contents of one of the mutable chambers to be fully displaced. After mixing of the substances is complete one or more of the following steps may be performed by the drug delivery pump (10) : needle insertion, opening of a sterile fluid pathway, drug delivery, and needle retraction. By providing these drug containers and drug delivery pumps medicaments may be stored as two or more separate constituents and mixed at or near time of delivery.
摘要翻译：本公开提供了药物容器，其允许在药物注射之前混合一种或多种物质和掺入这种药物容器的药物递送泵。通过将密封组件从关闭位置转换到可变室彼此流体连通的打开位置来启动包含在分离的可变室（64）（66）内的两种或多种物质的混合。通过使一个可变室的内容物被完全置换来引起连续的混合。物质的混合完成后，药物输送泵（10）可以执行以下一个或多个步骤：针插入，无菌流体通道的打开，药物递送和针回缩。通过提供这些药物容器和药物输送泵，药物可以作为两种或更多种单独的成分储存并在输送或接近输送时混合。

3. 发明申请

WO2016049501A1 CONCENTRIC BARREL DRUG CONTAINERS AND DRUG DELIVERY PUMPS THAT ALLOW MIXING AND DELIVERY 审中-公开
标题翻译：浓缩酒精饮料容器和药物输送泵，允许混合和输送
公开(公告)号：WO2016049501A1
公开(公告)日：2016-03-31
申请号：PCT/US2015/052311
申请日：2015-09-25
申请人： UNITRACT SYRINGE PTY LTD , COLLURA, Nicholas
发明人： COLLURA, Nicholas , WEAVER, Molly , HANSON, Ian
IPC分类号： A61M5/31 , A61M5/315
CPC分类号： A61M5/3129 , A61M5/31596 , A61M2005/31598
摘要： The present disclosure provides drug containers that allow for the mixing of one or more substances prior to drug injection and drug delivery pumps incorporating such drug containers. The drug delivery pumps may be wearable by a user. Mixing of the two or more substances contained within separate, mutable chambers is initiated by transforming an outer barrel distal seal (524) from a first position in which it covers ports (518) extending through an inner barrel (510) to a second position in which the outer barrel distal seal (524) does not cover the ports. Mixing is induced by forcing the contents of the outer chamber (526) through the ports and into the inner chamber, thereby by mixing with the contents of the inner chamber. After mixing of the substances is complete the mixed contents of the inner chamber are forced out of the inner chamber by distal displacement of an injection seal (512) located within the inner barrel. The contents may be delivered through a sterile pathway connection (300) and sterile fluid conduit (320) into the body of the patient. By providing these drug containers and drug delivery pumps that incorporate them, medicaments may be stored as two or more separate constituents and mixed at or near time of delivery.
摘要翻译：本公开提供了药物容器，其允许在药物注射之前混合一种或多种物质和掺入这种药物容器的药物递送泵。药物输送泵可以由使用者佩戴。通过将外筒远侧密封件（524）从第一位置转换而覆盖分开的可变室中的两种或多种物质的混合，其中第一位置覆盖延伸穿过内筒（510）的端口（518）至第二位置外筒远侧密封件（524）不覆盖端口。通过迫使外室（526）的内容物通过端口进入内室，从而通过与内室的内容物混合而引起混合。物料的混合完成后，通过位于内筒内的注射密封件（512）的远端位移将内室的混合内容物从内腔排出。内容物可以通过无菌通路连接（300）和无菌流体导管（320）输送到患者体内。通过提供包含它们的这些药物容器和药物输送泵，药物可以作为两种或更多种单独的成分储存并在输送或接近输送时混合。

4. 发明申请

WO2017139573A1 DRUG DELIVERY DEVICE 审中-公开
标题翻译：药物递送装置
公开(公告)号：WO2017139573A1
公开(公告)日：2017-08-17
申请号：PCT/US2017/017369
申请日：2017-02-10
申请人： UNITRACT SYRINGE PTY LTD , HANSON, Ian , BENTE, Paul , CICCIARELLI, Nicholas , DOUGHTY, Diane
发明人： HANSON, Ian , BENTE, Paul , CICCIARELLI, Nicholas , DOUGHTY, Diane
IPC分类号： A61M5/172 , A61M5/14 , A61M5/142 , A61M5/168 , A61M5/20
CPC分类号： A61M5/14248 , A61M5/1454 , A61M25/0606 , A61M2205/13 , A61M2205/276
摘要： Drug delivery devices are provided that are capable of delivering at a controlled rate a relatively large dosage form (for example, a 2 mL volume dosage form rather than a 1 mL dosage form) comprising a drug. Advantageously, these devices deliver the required dose of the drug with a generally acceptable level of pain intensity.
摘要翻译：提供了药物输送装置，其能够以受控的速率输送包含药物的相对较大的剂型（例如，2mL体积剂型而非1mL剂型）。有利地，这些装置以通常可接受水平的疼痛强度递送所需剂量的药物。

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