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1. 发明申请

WO2019152866A1 SYSTEMS, APPARATUS, AND METHODS FOR TRANSPORT AND DELIVERY OF THERAPEUTIC SUBSTANCE TO MIDDLE EAR 审中-公开
公开(公告)号：WO2019152866A1
公开(公告)日：2019-08-08
申请号：PCT/US2019/016389
申请日：2019-02-01
申请人： TUSKER MEDICAL, INC.
发明人： GOLDFARB, Eric , KERMANI, Mahyar Z. , GIROTRA, Rohit
IPC分类号： A61F11/00
摘要： Systems, apparatus, and methods are described for transporting and delivering a therapeutic substance to an ear of a subject, including a tubular element (216) configured for deployment in a tympanic membrane (TM) and a fluid transport element (230). The fluid transport element can be configured to transport the therapeutic substance from a proximal side to a distal side of the tubular element. Systems, apparatus, and methods further can include a fluid dispenser including a reservoir configured to contain a therapeutic substance, and a tubular element defining a lumen in fluid communication with an outlet in which the lumen and the outlet are configured to deliver the therapeutic substance from the reservoir to a region proximal to the tympanic membrane. Systems, apparatus, and methods further can include an electrode device.

2. 发明申请

WO2019089537A1 SYSTEMS, APPARATUS, AND METHODS FOR DELIVERY OF THERAPEUTIC SUBSTANCE TO NASAL CAVITY 审中-公开
公开(公告)号：WO2019089537A1
公开(公告)日：2019-05-09
申请号：PCT/US2018/058138
申请日：2018-10-30
申请人： TUSKER MEDICAL, INC.
发明人： GOLDFARB, Eric , GIROTRA, Rohit , KERMANI, Mahyar Z.
IPC分类号： A61K9/00 , A61M31/00 , A61M37/00 , A61N1/30
摘要： Systems, apparatus, and methods are described for delivering a therapeutic substance to a target area within or proximate to a nasal cavity of a subject, including a reservoir configured to contain the therapeutic substance and a delivery interface by which the therapeutic substance is delivered to the target area. In some embodiments, systems, apparatus, and methods described herein can deliver a therapeutic substance using iontophoresis and/or electroosmosis.

3. 发明申请

WO2019143587A1 VISUALIZATION DEVICES AND METHODS FOR OTOLOGIC PROCEDURES 审中-公开
公开(公告)号：WO2019143587A1
公开(公告)日：2019-07-25
申请号：PCT/US2019/013568
申请日：2019-01-15
申请人： TUSKER MEDICAL, INC.
发明人： GOLDFARB, Eric , KERMANI, Mahyar Z. , GIROTRA, Rohit
IPC分类号： A61B1/227 , A61B1/00 , A61B1/018
CPC分类号： A61B1/227 , A61B1/00052 , A61B1/00105 , A61B1/0014 , A61B1/00154 , A61B1/018
摘要： Systems, apparatuses, and methods are described for providing visualization inside an ear of a subject before, during, or after an otologic procedure. An apparatus (100) includes a light source (140), a sensor (130), a processor (152, 170), and a display (154, 172, 972). The light source (140) can be configured to provide incident light to a target area (TM), and the sensor (130) can be configured to capture reflected light from the target area (TM) to generate image data based on the reflected light. The processor (152, 170) can process the image data to produce an image of the target area (TM), and the display (154, 172, 972) can display the image of the target area (TM).

4. 发明申请

WO2017011777A1 EARPLUG ASSEMBLY FOR IONTOPHORESIS SYSTEM 审中-公开
标题翻译： EARPUG大会为IOPOPHORESIS系统
公开(公告)号：WO2017011777A1
公开(公告)日：2017-01-19
申请号：PCT/US2016/042577
申请日：2016-07-15
申请人： TUSKER MEDICAL, INC.
发明人： RAY, Miranda M. , GIROTRA, Rohit , TRUONG, Anh Quoc , PATEL, Radhika , GROSS, Thomas D. , CANTU, Alfredo
IPC分类号： A61F11/00 , A61M31/00 , A61N1/30 , A61N1/32 , A61N1/04
CPC分类号： A61F11/002 , A61F11/00 , A61M31/00 , A61N1/0428 , A61N1/0526 , A61N1/30 , A61N1/306 , A61N1/325
摘要： Systems, apparatus, and methods are disclosed for gripping and/or positioning a plug (320) in an ear canal outside a tympanic membrane, performing iontophoresis, and/or delivering a pressure equalization tube to the tympanic membrane, including a rigid body (323), an electrode (352), and/or a liner strip (380). The rigid body may define a channel (321), a vent path (329), and a reservoir (370) in fluid communication with the channel the vent path. The reservoir may be configured to increase the volume of the channel, thereby tolerating volumetric changes in the ear without exposing the electrode disposed within the channel to air. The electrode may define a longitudinal axis from which the reservoir extends laterally and proximally to increase a spacing between the electrode and the vent path. The liner strip may include a plurality of gripping portions and attachment portions to cover at least some of a pressure sensitive adhesive on the plug.
摘要翻译：公开了用于将耳塞（320）夹持和/或定位在鼓膜外部的耳道中，执行离子电渗疗法和/或将压力平衡管输送到包括刚体（323）的鼓膜的系统，装置和方法），电极（352）和/或衬垫条（380）。刚体可以限定通道（321），通气路径（329）和与通道流体连通的储存器（370）。储存器可以被配置为增加通道的体积，从而允许耳朵中的体积变化，而不将设置在通道内的电极暴露于空气。电极可以限定纵向轴线，储存器从该轴线横向和近侧延伸以增加电极和通气路径之间的间隔。衬垫条可以包括多个夹持部分和附接部分，以覆盖插头上的压敏粘合剂中的至少一些。

5. 发明申请

WO2021011855A1 SYSTEMS, DEVICES, AND METHODS FOR VISUALIZATION DURING MEDICAL PROCEDURES 审中-公开
公开(公告)号：WO2021011855A1
公开(公告)日：2021-01-21
申请号：PCT/US2020/042484
申请日：2020-07-17
申请人： TUSKER MEDICAL, INC.
发明人： DOMECUS, Brian , KERMANI, Mahyar Z. , GIROTRA, Rohit , GOLDFARB, Eric , LANTZ, Andrew , SCHNEIDER, Robert Edwin , BIGHAM, Tyler Bennett
IPC分类号： A61B1/00 , A61B1/227
摘要： Visualization during medical procedures is provided using a visualization system comprising: a control device defining an upper surface and a lower surface; a display visible through the upper surface of the control device; a handle coupled to the lower surface and extending away from the lower surface; a knob coupled to the control device, the knob configured to rotate about a rotational axis; an imaging assembly mechanically coupled to the knob and communicatively coupled to the control device, the imaging assembly configured to rotate around the rotational axis based on rotation of the knob; and the control device configured to display an image on the display, the image captured by the imaging assembly.

6. 发明申请

WO2018027102A1 SYSTEMS, APPARATUS, AND METHODS FOR DELIVERY OF THERAPEUTIC SUBSTANCE TO THE MIDDLE AND/OR INNER EAR 审中-公开
标题翻译：用于将治疗物质递送至中耳和/或内耳的系统，装置和方法
公开(公告)号：WO2018027102A1
公开(公告)日：2018-02-08
申请号：PCT/US2017/045438
申请日：2017-08-04
申请人： TUSKER MEDICAL, INC. , GOLDFARB, Eric , GIROTRA, Rohit , ABOLFATHI, Amir
发明人： GOLDFARB, Eric , GIROTRA, Rohit , ABOLFATHI, Amir
IPC分类号： A61F11/00
摘要： Systems (300), apparatus, and methods are described for delivering a therapeutic substance to an ear of a subject, including a reservoir (300) configured to contain the therapeutic substance and an outlet (320) configured to transport the therapeutic substance from the reservoir to a lumen of a tympanostomy tube disposed within a tympanic membrane bordering the tympanic cavity and/or the tympanic cavity via the lumen of the tympanostomy tube, such that the therapeutic substance can be delivered to the tympanic cavity and/or a round window to an inner ear bordering the tympanic cavity.
摘要翻译：描述了用于将治疗物质递送至受试者的耳朵的系统（300），装置和方法，所述系统（300），设备和方法包括被配置为容纳治疗物质的储存器（300）和被配置为以将治疗物质从储存器输送到设置在与鼓膜腔和/或鼓室腔接界的鼓膜内的鼓膜造口管的管腔，所述鼓膜通过鼓膜造口管的管腔，使得治疗物质可被输送到鼓室和/或与鼓室邻接的内耳的圆窗。

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