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1. 发明申请

WO2018027102A1 SYSTEMS, APPARATUS, AND METHODS FOR DELIVERY OF THERAPEUTIC SUBSTANCE TO THE MIDDLE AND/OR INNER EAR 审中-公开
标题翻译：用于将治疗物质递送至中耳和/或内耳的系统，装置和方法
公开(公告)号：WO2018027102A1
公开(公告)日：2018-02-08
申请号：PCT/US2017/045438
申请日：2017-08-04
申请人： TUSKER MEDICAL, INC. , GOLDFARB, Eric , GIROTRA, Rohit , ABOLFATHI, Amir
发明人： GOLDFARB, Eric , GIROTRA, Rohit , ABOLFATHI, Amir
IPC分类号： A61F11/00
摘要： Systems (300), apparatus, and methods are described for delivering a therapeutic substance to an ear of a subject, including a reservoir (300) configured to contain the therapeutic substance and an outlet (320) configured to transport the therapeutic substance from the reservoir to a lumen of a tympanostomy tube disposed within a tympanic membrane bordering the tympanic cavity and/or the tympanic cavity via the lumen of the tympanostomy tube, such that the therapeutic substance can be delivered to the tympanic cavity and/or a round window to an inner ear bordering the tympanic cavity.
摘要翻译：描述了用于将治疗物质递送至受试者的耳朵的系统（300），装置和方法，所述系统（300），设备和方法包括被配置为容纳治疗物质的储存器（300）和被配置为以将治疗物质从储存器输送到设置在与鼓膜腔和/或鼓室腔接界的鼓膜内的鼓膜造口管的管腔，所述鼓膜通过鼓膜造口管的管腔，使得治疗物质可被输送到鼓室和/或与鼓室邻接的内耳的圆窗。

2. 发明申请

WO2007147060A2 VISUALIZATION APPARATUS AND METHODS FOR TRANSSEPTAL ACCESS 审中-公开
标题翻译：可视化设备及其传输方法
公开(公告)号：WO2007147060A2
公开(公告)日：2007-12-21
申请号：PCT/US2007/071226
申请日：2007-06-14
申请人： VOYAGE MEDICAL, INC. , SAADAT, Vahid , ABOLFATHI, Amir , ROTHE, Chris A. , VAN BLADEL, Kevin A.
发明人： SAADAT, Vahid , ABOLFATHI, Amir , ROTHE, Chris A. , VAN BLADEL, Kevin A.
IPC分类号： A61B8/14
CPC分类号： A61B1/005 , A61B1/0008 , A61B1/00082 , A61B1/00085 , A61B1/00089 , A61B1/015 , A61B1/018 , A61B1/04 , A61B5/02007 , A61B8/12 , A61B8/4472
摘要： Visualization apparatus and methods for transseptal access are described herein where intravascular access across a septal wall is facilitated via devices which provide for direct visual viewing of tissue area. Such a system may include a deployment catheter and an attached imaging hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to the tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid can be pumped into the imaging hood until the fluid displaces any blood leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. Any number of therapeutic tools or a guidewire can be passed through the catheter and into the imaging hood for crossing the septal wall and passing the guidewire or instruments therethrough.
摘要翻译：本文描述了可视化装置和用于经常通路的方法，其中通过提供组织区域的直接视觉观察的装置促进通过隔壁的血管内通路。这样的系统可以包括部署导管和可展开成扩展配置的附接成像罩。在使用中，将成像罩放置在通常填充有不透明体液（例如血液）的体腔中的待成像组织上或邻近待成像的组织。半透明或透明流体可被泵送到成像罩中，直到流体移动通过部署导管中的成像元件离开要成像的组织的清晰区域的任何血液。任何数量的治疗工具或导丝可以通过导管并进入成像罩，用于穿过隔壁并使导丝或器械通过。

3. 发明申请

WO2007140367A2 METHODS AND APPARATUS FOR TRANSMITTING VIBRATIONS 审中-公开
标题翻译：传输振动的方法和装置
公开(公告)号：WO2007140367A2
公开(公告)日：2007-12-06
申请号：PCT/US2007/069885
申请日：2007-05-29
申请人： SONITUS MEDICAL, INC. , ABOLFATHI, Amir , SPIRIDIGLIOZZI, John
发明人： ABOLFATHI, Amir , SPIRIDIGLIOZZI, John
IPC分类号： H04R25/00
CPC分类号： H04R25/606 , A61C5/00 , A61C8/0093 , A61C8/0098 , B33Y70/00 , B33Y80/00 , H04R1/46 , H04R3/04 , H04R25/554 , H04R25/602 , H04R25/604 , H04R2225/31 , H04R2225/67 , H04R2420/07 , H04R2460/01 , H04R2460/13
摘要： Methods and apparatus for transmitting vibrations via an electronic and/or transducer assembly through a tooth or teeth are disclosed herein. The assembly may include a bracket which is adhered or affixed onto the tooth or teeth and an electronics and/or transducer assembly which may be removably coupled to the bracket. The electronic and/or transducer assembly may receive incoming sounds either directly or through a receiver to process and amplify the signals and transmit the processed sounds via a vibrating transducer element coupled to the bracket for transmission into the underlying tooth or other bone structure.
摘要翻译：本文公开了通过电子和/或换能器组件通过齿或齿传递振动的方法和装置。组件可以包括粘附或固定到齿或齿上的支架以及可拆卸地联接到支架的电子装置和/或换能器组件。电子和/或换能器组件可以直接地或通过接收器接收输入声音，以处理和放大信号，并经由耦合到支架的振动换能器元件发送经处理的声音，以便传输到下面的牙齿或其他骨骼结构中。

4. 发明申请

WO2006060547A2 SYSTEMS AND METHODS FOR INTRA-ORAL DRUG DELIVERY 审中-公开
标题翻译：用于口服药物递送的系统和方法
公开(公告)号：WO2006060547A2
公开(公告)日：2006-06-08
申请号：PCT/US2005/043431
申请日：2005-11-29
申请人： ALIGN TECHNOLOGY, INC. , LI, Chunhua , CARLYLE, Wenda, C. , DE SMEDT, Philippe , ABOLFATHI, Amir , KUO, Eric, E. , TRICCA, Robert, E. , CHEN, Jennifer, C. , WU, Benjamin, M.
发明人： LI, Chunhua , CARLYLE, Wenda, C. , DE SMEDT, Philippe , ABOLFATHI, Amir , KUO, Eric, E. , TRICCA, Robert, E. , CHEN, Jennifer, C. , WU, Benjamin, M.
IPC分类号： A61C17/00
CPC分类号： A61C19/063 , A61C7/00 , A61C7/008 , A61C7/08 , A61C8/00
摘要： Systems and methods are disclosed for intra-oral delivery of drugs.
摘要翻译：公开了用于口服内递送药物的系统和方法。

5. 发明申请

WO2006036597A1 SYSTEMS AND METHODS FOR DENTAL APPLIANCE COMPLIANCE INDICATION 审中-公开
标题翻译：牙科器具符合性指标的系统和方法
公开(公告)号：WO2006036597A1
公开(公告)日：2006-04-06
申请号：PCT/US2005/033196
申请日：2005-09-16
申请人： ALIGN TECHNOLOGY, INC. , ABOLFATHI, Amir , CHEN, Jennifer C. , LI, Chunhua , TRICCA, Robert E. , WU, Benjamin M.
发明人： ABOLFATHI, Amir , CHEN, Jennifer C. , LI, Chunhua , TRICCA, Robert E. , WU, Benjamin M.
IPC分类号： A61C3/00
CPC分类号： A61C7/00 , A61C7/08 , A61C19/04 , A61C19/063
摘要： An apparatus for monitoring orthodontic treatment compliance includes an appliance adapted to be worn over one or more teeth; and a compliance indicator mounted on the appliance to indicate compliance.
摘要翻译：用于监测正畸治疗依从性的装置包括适于佩戴在一个或多个牙齿上的器具; 以及安装在设备上以指示合规性的合规性指示符。

6. 发明申请

WO2010132399A1 HEADSET SYSTEMS AND METHODS 审中-公开
标题翻译： HEADSET系统和方法
公开(公告)号：WO2010132399A1
公开(公告)日：2010-11-18
申请号：PCT/US2010/034312
申请日：2010-05-11
申请人： SONITUS MEDICAL, INC. , ABOLFATHI, Amir , SHELTON, Jason, R , KASSAYAN, Reza
发明人： ABOLFATHI, Amir , SHELTON, Jason, R , KASSAYAN, Reza
IPC分类号： H04R25/00
CPC分类号： H04R1/083 , B33Y70/00 , B33Y80/00 , G11B33/06 , H04R1/1091 , H04R3/00 , H04R2460/13
摘要： A digital audio player device can be attached, adhered, or otherwise embedded into or upon a removable oral appliance or other oral device to form an intraoral MP3 player. In another embodiment, the device provides an electronic and transducer device that can be attached, adhered, or otherwise embedded into or upon a removable oral appliance or other oral device to form a DAP. Such an oral appliance may be a custom-made device fabricated from a thermal forming process utilizing a replicate model of a dental structure obtained by conventional dental impression methods. The electronic and transducer assembly may receive incoming sounds either directly or through a receiver to process and amplify the signals and transmit the processed sounds via a vibrating transducer element coupled to a tooth or other bone structure, such as the maxillary, mandibular, or palatine bone structure.
摘要翻译：数字音频播放器装置可以被附接，粘附或以其它方式嵌入到可拆卸的口器具或其它口腔装置中或之上，以形成口内MP3播放器。在另一个实施例中，该装置提供电子和换能器装置，其可以附接，粘附或以其它方式嵌入可移除的口器具或其他口腔装置中或其上，以形成DAP。这样的口器具可以是使用通过常规牙印模法获得的牙科结构的重复模型的热成型方法制造的定制装置。电子和换能器组件可以直接或通过接收器接收输入声音，以处理和放大信号，并经由耦合到牙齿或其它骨结构（例如上颌骨，下颌骨或腭骨）的振动换能器元件传送经处理的声音结构体。

7. 发明申请

WO2009102889A1 HEADSET SYSTEMS AND METHODS 审中-公开
标题翻译： HEADSET系统和方法
公开(公告)号：WO2009102889A1
公开(公告)日：2009-08-20
申请号：PCT/US2009/033953
申请日：2009-02-12
申请人： SONITUS MEDICAL, INC. , ABOLFATHI, Amir
发明人： ABOLFATHI, Amir
IPC分类号： H04R25/00
CPC分类号： H04R1/1091 , B33Y70/00 , B33Y80/00 , H04R25/606 , H04R2460/13
摘要： A wireless headset is adapted to communicate with a sound source such as a music player or a cell phone or a suitable audio or sound communicated through a one-way or two-way communication device. The headset includes a mouth wearable communicator; and a linking unit coupled to the mouth wearable communicator, the linking unit adapted to communicate with the sound source.
摘要翻译：无线耳机适于与诸如音乐播放器或蜂窝电话的声源或通过单向或双向通信设备传送的合适的音频或声音进行通信。头戴式耳机包括口戴式穿戴式通讯器; 以及连接单元，其联接到所述口部可佩戴通信器，所述连接单元适于与所述声源通信。

8. 发明申请

WO2007140373A3 ACTUATOR SYSTEMS FOR ORAL-BASED APPLIANCES 审中-公开
公开(公告)号：WO2007140373A3
公开(公告)日：2007-12-06
申请号：PCT/US2007/069892
申请日：2007-05-29
申请人： SONITUS MEDICAL, INC. , MENZEL, Christoph , ABOLFATHI, Amir
发明人： MENZEL, Christoph , ABOLFATHI, Amir
IPC分类号： H04R25/00
摘要： Actuator systems for oral-based appliances utilizing transducers which are attached, adhered, or otherwise embedded into or upon a dental or oral appliance to form a hearing aid assembly. Such oral appliances may be a custom-made device which receives incoming sounds and transmits the processed sounds via a vibrating transducer element. The transducer element may utilize electromagnetic or piezoelectric transducer mechanisms and may be positioned directly along the dentition or along an oral appliance housing in various configurations.

9. 发明申请

WO2006020911A2 DENTAL PLIERS FOR FORMING AND REMOVING BUMPS ON APPLIANCES 审中-公开
标题翻译：用于成型和拆卸电器用的牙科用牙具
公开(公告)号：WO2006020911A2
公开(公告)日：2006-02-23
申请号：PCT/US2005/028817
申请日：2005-08-11
申请人： ALIGN TECHNOLOGY, INC. , ABOLFATHI, Amir , ASSELIN, Brian, K. , KUO, Eric , PHAN, Loc, X.
发明人： ABOLFATHI, Amir , ASSELIN, Brian, K. , KUO, Eric , PHAN, Loc, X.
IPC分类号： A61C3/00 , A61C3/14
CPC分类号： A61C7/04 , A61C7/08
摘要： Pliers for forming and removing bumps for the dental appliance without heating are disclosed. The pliers for making the bumps include a first elongated member having a first jaw portion at one end and a handle portion at the other end, the jaw portion having a projection mounted at a distal end of the first jaw portion; and a second elongated member joined to the first elongated member, the second elongated member having a second jaw portion at one end and a second handle portion at the other end, the second jaw portion adapted to receive the projection to create the bump in the dental appliance without heating. The bump can be supplemented with a material such as an adhesive.
摘要翻译：公开了用于在没有加热的情况下形成和去除牙科用具的凸块的钳子。用于制造凸块的钳子包括第一细长构件，其在一端具有第一钳口部分和在另一端具有手柄部分，钳口部分具有安装在第一钳口部分的远端处的突出部; 以及连接到所述第一细长构件的第二细长构件，所述第二细长构件在一端具有第二钳口部分和在另一端具有第二手柄部分，所述第二钳口部分适于接收所述突起以在牙齿中产生凸起家用电器不加热。凸块可以用诸如粘合剂的材料补充。

10. 发明申请

WO2005094436A2 ROOT-BASED TOOTH MOVING SEQUENCING 审中-公开
标题翻译：基于ROOT的牙齿移动顺序
公开(公告)号：WO2005094436A2
公开(公告)日：2005-10-13
申请号：PCT/US2005/007701
申请日：2005-03-08
申请人： ALIGN TECHNOLOGY, INC. , ABOLFATHI, Amir , BEERS, Andrew, C.
发明人： ABOLFATHI, Amir , BEERS, Andrew, C.
IPC分类号： A61C3/00 , A61C7/00
CPC分类号： A61C7/00 , A61C7/002 , B33Y80/00
摘要： Systems and methods are disclosed for repositioning the teeth of a patient by providing a digital model of each tooth of the patient; determining one or more root parameters from the digital model; and digitally moving one or more tooth models and evaluating a treatment outcome based on one or more root movement clinical constraints.
摘要翻译：公开了通过提供患者的每个牙齿的数字模型来重新定位患者的牙齿的系统和方法; 从数字模型确定一个或多个根参数; 并且数字地移动一个或多个牙齿模型并基于一个或多个根移动临床约束来评估治疗结果。

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