专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2011045811A1 FUSED THIAZOLO AND OXAZOLO PYRIMIDINONES 审中-公开
标题翻译：熔化的噻唑和氧化吡咯烷酮
公开(公告)号：WO2011045811A1
公开(公告)日：2011-04-21
申请号：PCT/IN2010/000579
申请日：2010-08-31
申请人： TORRENT PHARMACEUTICALS LIMITED , SRIVASTAVA, Sanjay , CHHIPA, Laxmikant , GUPTA, Ramesh, Chandra , DESHPANDE, Shailesh , CHAUDHARI, Anita , MOHANAN, Anookh , DUTT, Chaitanya , CHAUTHAIWALE, Vijay , BADANTHADKA, Murali , JAMADARKHANA, Prashant, G.
发明人： SRIVASTAVA, Sanjay , CHHIPA, Laxmikant , GUPTA, Ramesh, Chandra , DESHPANDE, Shailesh , CHAUDHARI, Anita , MOHANAN, Anookh , DUTT, Chaitanya , CHAUTHAIWALE, Vijay , BADANTHADKA, Murali , JAMADARKHANA, Prashant, G.
IPC分类号： C07D513/06 , C07D513/16 , A61K31/519 , A61P7/06
CPC分类号： C07D513/06 , C07D513/16
摘要： The present invention relates to novel compounds, their pharmaceutically acceptable salts, and their isomers, steroisomers, conformers, tautomers, polymorphs, hydrates and solvates. The present invention also encompasses pharmaceutically acceptable compositions of said compounds and process for preparing novel compounds. The invention further relates to the use of the above-mentioned compounds for the preparation of medicament for use as pharmaceuticals.
摘要翻译：本发明涉及新化合物，其药学上可接受的盐及其异构体，立体异构体，构象异构体，互变异构体，多晶型物，水合物和溶剂合物。本发明还包括所述化合物的药学上可接受的组合物和制备新化合物的方法。本发明还涉及上述化合物在制备用作药物的药物中的用途。

2. 发明申请

WO2011048611A1 NOVEL FUSED PYRIDAZINE DERIVATIVES 审中-公开
标题翻译：新型氟化物吡啶衍生物
公开(公告)号：WO2011048611A1
公开(公告)日：2011-04-28
申请号：PCT/IN2010/000664
申请日：2010-10-06
申请人： TORRENT PHARMACEUTICALS LIMITED , KUMAR, Prabhat , GHALASASI, Sameer , GUPTA, Ramesh, Chandra , DESHPANDE, Shailesh , MOHANAN, Anookh , CHAUDHARI, Anita , DUTT, Chaitanya , CHAUTHAIWALE, Vijay , MANDHARE, Appaji, Baburao
发明人： KUMAR, Prabhat , GHALASASI, Sameer , GUPTA, Ramesh, Chandra , DESHPANDE, Shailesh , MOHANAN, Anookh , CHAUDHARI, Anita , DUTT, Chaitanya , CHAUTHAIWALE, Vijay , MANDHARE, Appaji, Baburao
IPC分类号： A61K31/495 , C07D487/04 , C07D487/14 , A61P9/00
CPC分类号： C07D487/04 , C07D487/14
摘要： The present invention relates to novel fused pyridazine compounds, their pharmaceutically acceptable salts, and their isomers, stereoisomers, conformers, tautomers, polymorphs, hydrates and solvates. The present invention also encompasses pharmaceutically acceptable compositions of said compounds and process for preparing novel compounds. The invention further relates to the use of the above-mentioned compounds for the preparation of medicament for use as pharmaceuticals.
摘要翻译：本发明涉及新的稠合哒嗪化合物及其药学上可接受的盐及其异构体，立体异构体，构象异构体，互变异构体，多晶型物，水合物和溶剂合物。本发明还包括所述化合物的药学上可接受的组合物和制备新化合物的方法。本发明还涉及上述化合物在制备用作药物的药物中的用途。

3. 发明申请

WO2010128528A2 NOVEL HETEROCYCLIC COMPOUNDS 审中-公开
标题翻译：新型杂环化合物
公开(公告)号：WO2010128528A2
公开(公告)日：2010-11-11
申请号：PCT/IN2010/000295
申请日：2010-05-06
申请人： TORRENT PHARMACEUTICALS LIMITED , DUTT, Chaitanya , CHAUTHAIWALE, Vijay , GUPTA, Ramesh, Chandra , PATEL, Manish , KOTECHA, Jignesh , LATAD, Sachin , ABRAHAM, Jaya , SRIVASTAVA, Sanjay , RODE, Milind , DESHPANDE, Shailesh , CHAUDHARY, Anita , KESARWANI, Amit, Kumar
发明人： DUTT, Chaitanya , CHAUTHAIWALE, Vijay , GUPTA, Ramesh, Chandra , PATEL, Manish , KOTECHA, Jignesh , LATAD, Sachin , ABRAHAM, Jaya , SRIVASTAVA, Sanjay , RODE, Milind , DESHPANDE, Shailesh , CHAUDHARY, Anita , KESARWANI, Amit, Kumar
IPC分类号： C07D211/56
CPC分类号： C07D409/06 , C07D211/56 , C07D211/60 , C07D401/04 , C07D401/14 , C07D405/14 , C07D409/14 , C07D417/04
摘要： The present invention relates to a new class of heterocyclic compounds and pharmaceutically acceptable salts thereof, process for preparing the same, pharmaceutical composition containing these compounds and to their use in treatment of diseases caused due to formation and accumulation of AGEs (Advanced Glycation endproducts). The compounds of the present invention are useful for the treatment of diabetic and aging-related complications caused by formation and accumulation of AGEs, such as neuropathy, nephropathy, microangiopathy, retinopathy, hypertension, heart failure, atherosclerosis, Alzheimer's disease & dermatological disorders.
摘要翻译：本发明涉及一类新的杂环化合物及其药学上可接受的盐，其制备方法，含有这些化合物的药物组合物及其用于治疗由于AGEs的形成和积累引起的疾病（高级糖化终产物）。本发明的化合物可用于治疗由AGEs的形成和积累引起的糖尿病和老化相关并发症，例如神经病，肾病，微血管病变，视网膜病变，高血压，心力衰竭，动脉粥样硬化，阿尔茨海默病和皮肤病。

4. 发明申请

WO2005097746A2 2-PROPENE-1-ONES AS HSP 70 INDUCERS 审中-公开
标题翻译： 2-PROPENE-1-ONES作为HSP 70感应器
公开(公告)号：WO2005097746A2
公开(公告)日：2005-10-20
申请号：PCT/IN2005/000112
申请日：2005-04-11
申请人： TORRENT PHARMACEUTICALS LTD , KUMAR, Prabhat , MANE, Uttam, Rajaram , GUPTA, Ramesh, Chandra , NADKARNI, Sunil, Sadanand , MOHANAN, Anookh , TANDON, Ruchi , MUNSHI, Siralee
发明人： KUMAR, Prabhat , MANE, Uttam, Rajaram , GUPTA, Ramesh, Chandra , NADKARNI, Sunil, Sadanand , MOHANAN, Anookh , TANDON, Ruchi , MUNSHI, Siralee
IPC分类号： C07D213/00
CPC分类号： C07D215/42 , C07D213/72 , C07D215/14 , C07D241/12 , C07D241/18 , C07D241/44 , C07D401/04 , C07D401/10 , C07D401/14 , C07D403/10 , C07D403/12 , C07D405/12 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/12
摘要： The present invention relates to novel compounds of 2-propene-1-one series, of general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, pharmaceutically acceptable salts, pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them, wherein R 5 , R 6 , Q and Y are as defined in the specification. The present invention also relates to a process for preparing such compounds, compositions containing such compounds, and use of such compound and composition in medicine. The compounds of the general formula (I) induce HSP-70 and are useful for the treatment of diseases accompanying pathological stress in a living mammalian organism, including a human being, such as stroke, myocardial infarction, inflammatory disorder, hepatotoxicity, sepsis, diseases of viral origin, allograft rejection, tumourous diseases, gastric mucosal damage, brain haemorrhage, endothelial dysfunctions, diabetic complications, neuro-degenerative diseases, post-traumatic neuronal damage, acute renal failure, glaucoma and aging related skin degeneration.
摘要翻译：本发明涉及通式（I）的2-丙烯-1-酮系列的新化合物，其衍生物，类似物，互变异构形式，立体异构体，多晶型物，药学上可接受的盐，药学上可接受的溶剂化物和含有它们的药学上可接受的组合物，其中R5，R6，Q和Y如说明书中所定义。本发明还涉及制备这种化合物的方法，含有这些化合物的组合物，以及这些化合物和组合物在医药中的用途。通式（I）的化合物诱导HSP-70，并且可用于治疗活的哺乳动物生物体中伴随病理应激的疾病，包括人类，如中风，心肌梗死，炎性疾病，肝毒性，败血症，疾病病毒来源，同种异体移植排斥，肿瘤性疾病，胃粘膜损伤，脑出血，内皮功能障碍，糖尿病并发症，神经退行性疾病，创伤后神经元损伤，急性肾功能衰竭，青光眼和衰老相关的皮肤退化。

5. 发明申请

WO2018164749A1 EXPANDABLE JACKET FOR TRIAXIAL, UNCONFINED AND UNIAXIAL COMPRESSION TESTS AND TEST DEVICE FOR THREE-DIMENSIONAL CONSOLIDATION AND SETTLEMENT TESTS 审中-公开
公开(公告)号：WO2018164749A1
公开(公告)日：2018-09-13
申请号：PCT/US2017/066882
申请日：2017-12-15
申请人： GUPTA, Ramesh, Chandra
发明人： GUPTA, Ramesh, Chandra
IPC分类号： G01N3/08 , G01N3/24
摘要： The expandable jacket and flexible ring comprises of the segmented circular arch shaped plates and bands or rings around the segmented plates. The test preparation consists of a membrane surrounding a specimen with or without a filter, segmented plates surrounding the membrane, and bands or rings around the segmented plates to permit uniform radial expansion of the specimen through its height when increments of vertical load are applied during the test, thereby providing accurate values of area of cross- section, deviator stress, volume change, modulus of elasticity, Poisson's ratio and shear strength. Using the flexible ring, three-dimensional consolidation tests are performed to determine three-dimensional coefficient of consolidation and coefficients of consolidation in horizontal and vertical directions. Removable attachments are used for assembling the expandable jacket and flexible ring during the test. A calibration device is used to determine the modulus of elasticity of the membrane and expandable jacket and flexible ring.

6. 发明申请

WO2005095418A1 SULFONAMIDE-THIAZOLPYRIDINE DERIVATIVES AS GLUCOKINASE ACTIVATORS USEFUL THE TREATMENT OF TYPE 2 DIABETES 审中-公开
标题翻译：作为GLUCOKINASE激活剂的磺酰胺 - 噻唑吡啶衍生物有助于治疗2型糖尿病
公开(公告)号：WO2005095418A1
公开(公告)日：2005-10-13
申请号：PCT/EP2005/003456
申请日：2005-04-01
申请人： NOVARTIS AG , NOVARTIS PHARMA GMBH , BEBERNITZ, Gregory, Raymond , GUPTA, Ramesh, Chandra , JAGTAP, Vikrant, Vijaykumar , MANDHARE, Appaji, Baburao , TULI, Davinder
发明人： BEBERNITZ, Gregory, Raymond , GUPTA, Ramesh, Chandra , JAGTAP, Vikrant, Vijaykumar , MANDHARE, Appaji, Baburao , TULI, Davinder
IPC分类号： C07D513/04
CPC分类号： C07D513/04
摘要： The present invention provides compounds of the formula (I), which are activators of glucokinase activity and, thus, may be employed as therapeutic agents for the treatment of glucokinase mediated conditions. Accordingly, the compounds of formula (I) may be employed for the prevention and the treatment of impaired glucose tolerance, Type 2 diabetes and obesity.
摘要翻译：本发明提供了作为葡萄糖激酶活性的激活剂的式（I）化合物，因此可用作治疗葡糖激酶介导的病症的治疗剂。因此，式（I）化合物可用于预防和治疗葡萄糖耐量异常，2型糖尿病和肥胖症。

7. 发明申请

WO2007032028A1 THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS 审中-公开
标题翻译：噻吗啉和氧化氮及其作为PTP1B抑制剂的用途
公开(公告)号：WO2007032028A1
公开(公告)日：2007-03-22
申请号：PCT/IN2006/000368
申请日：2006-09-15
申请人： TORRENT PHARMACEUTICALS LTD. , BANERJEE, Rakesh, Kumar , GUPTA, Ramesh, Chandra , TULI, Davinder , RODE, Milind , SHUTHAR, Bharat , UMRANI, Dhananjay , PATHAK, Padmaja , CHOKSI, Tejal , CHAUDHARY, Anita
发明人： BANERJEE, Rakesh, Kumar , GUPTA, Ramesh, Chandra , TULI, Davinder , RODE, Milind , SHUTHAR, Bharat , UMRANI, Dhananjay , PATHAK, Padmaja , CHOKSI, Tejal , CHAUDHARY, Anita
IPC分类号： C07D277/42 , C07D263/48 , C07D417/06 , C07D417/12 , C07D417/14 , C07D413/06 , C07D413/12 , C07D413/14 , C07F9/6539 , A61K31/42 , A61K31/425 , A61P3/10
CPC分类号： C07F9/6539 , C07D263/48 , C07D277/20 , C07D277/42 , C07D413/06 , C07D413/12 , C07D413/14 , C07D417/06 , C07D417/12 , C07D417/14
摘要： The present invention encompasses; the novel substituted heterocyclic compounds represented by formula (I) or their pharmaceutically acceptable salts, wherein the substituents in formula (I) have the meanings as defined in the specification. The invention also encompasses process for preparing such compound, pharmaceutical compositions and methods of treating or preventing PTP-1B mediated diseases.
摘要翻译：本发明包括由式（I）表示的新型取代的杂环化合物或其药学上可接受的盐，其中式（I）中的取代基具有如说明书中所定义的含义。本发明还包括制备这种化合物的方法，药物组合物和治疗或预防PTP-1B介导的疾病的方法。

8. 发明申请

WO2005095417A1 THIAZOLOPYRIDINE DERIVATES, PHARMACEUTICAL CONDITIONS CONTAINING THEM AND METHODS OF TREATING GLUCOKINASE MEDIATED CONDITIONS 审中-公开
标题翻译：噻唑吡啶衍生物，含有它们的药物条件和处理葡萄糖激酶介导的条件的方法
公开(公告)号：WO2005095417A1
公开(公告)日：2005-10-13
申请号：PCT/EP2005/003454
申请日：2005-04-01
申请人： NOVARTIS AG , NOVARTIS PHARMA GMBH , BEBERNITZ, Gregory, Raymond , GUPTA, Ramesh, Chandra , JAGTAP, Vikrant, Vijaykumar , MANDHARE, Appaji, Baburao , TULI, Davinder
发明人： BEBERNITZ, Gregory, Raymond , GUPTA, Ramesh, Chandra , JAGTAP, Vikrant, Vijaykumar , MANDHARE, Appaji, Baburao , TULI, Davinder
IPC分类号： C07D513/04
CPC分类号： C07D513/04
摘要： The present invention provides compounds of the formula (I) which are activators of glucokinase activity and, thus, may be employed as therapeutic agents for the treatment of glucokinase mediated conditions. Accordingly, the compounds of formula (I) may be employed for the prevention and the treatment of impaired glucose tolerance, Type 2 diabetes and obesity.
摘要翻译：本发明提供作为葡萄糖激酶活性的激活剂的式（I）化合物，因此可用作治疗葡糖激酶介导的病症的治疗剂。因此，式（I）化合物可用于预防和治疗葡萄糖耐量异常，2型糖尿病和肥胖症。

9. 发明申请

WO2021262223A1 RAPID CONSOLIDATION AND COMPACTION METHOD FOR SOIL IMPROVEMENT OF VARIOUS LAYERS OF SOILS AND INTERMEDIATE GEOMATERIALS IN A SOIL DEPOSIT 审中-公开
公开(公告)号：WO2021262223A1
公开(公告)日：2021-12-30
申请号：PCT/US2020/061495
申请日：2020-11-20
申请人： GUPTA, Ramesh, Chandra
发明人： GUPTA, Ramesh, Chandra
IPC分类号： E02D5/24 , E02D3/08 , E02D7/02 , E02D27/16 , E02D27/18 , E02D27/32 , E02D13/04 , E02D27/34 , E02D7/16
摘要： The rapid consolidation and compaction method comprises (i) first driving a hollow pipe, (ii) driving a pipe with a removable end plate after filling and compacting the sandy material in it, through the hollow pipe, to required depth, creating high excess pore-water pressures in the range of 50 to 300 KPa in clayey soils, (iv) pulling out the pipe section leaving behind the removable end plate and thereby installing porous displacement piles which allows dissipation of the excess pore-water pressures horizontally to the porous displacement pile, in which the excess water flows out vertically to the ground surface, and (v) the length of the drainage path is reduced to half the spacing between adjoining porous displacement piles, allowing rapid consolidation resulting in increase in density. Installing the porous displacement piles in the layer of loose to medium dense sand layer results in the instantaneous increase in its density.

10. 发明申请

WO2016149128A1 EXPANDABLE JACKET AND ITS CALIBRATION DEVICE FOR TRIAXIAL TESTS ON SOILS 审中-公开
标题翻译：可膨胀夹克及其标定装置在土壤三轴测试中的应用
公开(公告)号：WO2016149128A1
公开(公告)日：2016-09-22
申请号：PCT/US2016/022136
申请日：2016-03-11
申请人： GUPTA, Ramesh, Chandra
发明人： GUPTA, Ramesh, Chandra
IPC分类号： E02D1/02 , E02D1/04 , G01N3/08 , G01N33/24
CPC分类号： G01N33/24 , G01N3/08
摘要： During triaxial compression test, a soil specimen experiences reduction of its height with increase in its diameter. New cross-sectional area is calculated assuming uniform increase in diameter. This condition is seldom met in actual soil specimens, because specimen undergoes non-uniform increase in diameter and very often with localized bulging in specimen affecting the accuracy of calculation of deviator stress, shear strength and volume change characteristics. The expandable jacket included in this invention consists of circular segmental metal plates wrapped around the soil specimen and elastomeric rubber bands or rings around the segmental plates to permit uniform radial expansion and maintain uniform diameter of the specimen during the test and thereby providing accurate values of deviator stress, volume change characteristics and shear strength of soil specimen. The calibration device for calibration of expandable jacket shall provide the magnitude of correction to be made in deviator stress.
摘要翻译：在三轴压缩试验中，土壤样品随着其直径的增加而降低其高度。假设直径均匀增加，计算新的横截面积。这种情况在实际土壤试样中很少遇到，因为试样的直径不均匀增大，而且经常会出现局部的试样膨胀，影响偏应力，剪切强度和体积变化特性的计算精度。包括在本发明中的可膨胀护套包括围绕土壤试样包裹的圆形金属片和围绕分隔片的弹性橡胶带或环，以允许均匀的径向膨胀并且在试验过程中保持试样的均匀直径，从而提供偏离器的准确值应力，体积变化特征和土体试样的抗剪强度。校准膨胀套的校准装置应提供偏应力校正量。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式