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1. 发明申请

WO2002100466A3 MICROFABRICATED SURGICAL DEVICES AND METHODS OF MAKING THE SAME 审中-公开
公开(公告)号：WO2002100466A3
公开(公告)日：2002-12-19
申请号：PCT/US2002/017666
申请日：2002-06-06
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , STUPAR, Philip, Anthony , PISANO, Albert, P.
发明人： STUPAR, Philip, Anthony , PISANO, Albert, P.
IPC分类号： A61M5/32 , A61B17/34
摘要： This invention relates to microfabricated surgical devices and methods of making the same. One such device includes an end portion and a body portion wherein at least a part of the body portion is hollow and includes a conformally coated polymer formed on inside and outside surfaces of the body portion. One such method includes defining at least one channel (14a, 16a) in the surface of a first substrate (10), joining a second substrate (12) to the first substrate (10) to cover the channel (14, 16), forming a trench (18, 20, 22) in the first (10) and second substrates (12) on each side of the channel (14, 16) define a shell structure, and releasing the shell structure from the first and second substrates.

2. 发明申请

WO2003024310A2 A METHOD OF INTERVENTIONAL SURGERY 审中-公开
标题翻译：一种传统手术方法
公开(公告)号：WO2003024310A2
公开(公告)日：2003-03-27
申请号：PCT/US2002/029665
申请日：2002-09-20
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , SEWARD, Kirk, Patrick , PISANO, Albert, P.
发明人： SEWARD, Kirk, Patrick , PISANO, Albert, P.
IPC分类号： A61B
CPC分类号： A61B17/3478 , A61B2017/00247 , A61B2017/00345 , A61B2017/00398 , A61B2017/22061 , A61B2017/22075 , A61B2018/00392 , A61M25/0084 , A61M2025/0086 , A61M2025/0087 , A61M2025/009 , A61M2025/0093 , A61M2025/1086
摘要： A method of interventional surgery is described. The method may include inserting an actuator within a body of a vascularized organism and positioning the actuator adjacent a target region within a vessel of the body. The actuator is operated to cause a needle thereof to move in a substantially perpendicular direction relative to a wall of the vessel to produce an opening therein. A therapeutic or diagnostic agent may be delivered by the needle to the target region via the opening in the vessel wall.
摘要翻译：描述介入手术的方法。该方法可以包括将致动器12插入血管化生物的体内，并将致动器12定位在身体的容器内的目标区域附近。操作致动器12使其针14相对于容器的壁沿基本上垂直的方向移动，以在其中产生开口。治疗或诊断剂可以经由针14经由容器中的开口递送到目标区域。

3. 发明申请

WO1997049475A1 MICROFABRICATED FILTER AND SHELL CONSTRUCTED WITH A PERMEABLE MEMBRANE 审中-公开
标题翻译：微孔过滤器和壳体用可渗透膜构成
公开(公告)号：WO1997049475A1
公开(公告)日：1997-12-31
申请号：PCT/US1997010221
申请日：1997-05-29
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , LEBOUITZ, Kyle, S. , HOWE, Roger, T. , PISANO, Albert, P.
IPC分类号： B01D24/02
CPC分类号： B81C1/00333 , B01D67/0072 , B01D67/0093 , B01D71/02 , B01D2323/225 , B01D2325/04 , B01L3/502707 , B01L3/502753 , B01L2200/12 , B01L2300/0681 , B81C1/00158 , G01N33/491 , G03F7/00
摘要： Microfabricated filters (100) constructed with permeable polysilicon membranes (104) and methods for fabricating such filters. The filters include a frame structure (102) having a plurality of openings (103) therethrough and a permeable polysilicon membrane disposed over the openings in the frame structure. The frame structure provides support for the permeable polysilicon membrane. The pores of the filter may be smaller than the resolution limit of photolithography. The width of the pores may be as small as about 0.05 microns. The filters feature a relatively high throughput due to the extremely short pore length. The filters may be fabricated utilizing standard microfabrication processes. Also, microfabricated shells constructed with permeable membranes for encapsulating microfabricated devices such as microelectromechanical structures (MEMS) and methods for fabricating such shells. The shells include a frame structure having a plurality of openings therethrough, a permeable membrane disposed on the openings through the frame structure, an optional sealing cavity bounded by the frame structure. The permeable membrane may be a thin film layer of polysilicon having a thickness of less than 0.3 microns.
摘要翻译：用可渗透多晶硅膜（104）构成的微型过滤器（100）和用于制造这种过滤器的方法。过滤器包括具有穿过其中的多个开口（103）的框架结构（102）和设置在框架结构中的开口上方的可渗透多晶硅膜。框架结构为可渗透多晶硅膜提供支撑。滤光器的孔可以小于光刻的分辨率极限。孔的宽度可以小至约0.05微米。由于孔长度非常短，过滤器的生产量相对较高。可以使用标准微加工工艺来制造过滤器。而且，用可封装微结构器件（例如微机电结构（MEMS））和用于制造这种壳的方法的可渗透膜构成的微制造壳体。壳体包括具有穿过其中的多个开口的框架结构，通过框架结构设置在开口上的可渗透膜，由框架结构限定的可选密封腔。可渗透膜可以是厚度小于0.3微米的多晶硅薄膜层。

4. 发明申请

WO2002062242A1 EPIDERMAL ABRASION DEVICE MOLD, AND METHOD OF FABRICATING SAME 审中-公开
标题翻译：表面磨损装置模具及其制造方法
公开(公告)号：WO2002062242A1
公开(公告)日：2002-08-15
申请号：PCT/US2001/050349
申请日：2001-11-09
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人： LEBOUITZ, Kyle, S. , PISANO, Albert, P.
IPC分类号： A61B17/50
CPC分类号： A61M37/0015 , A61B5/0492 , A61B5/14542 , A61B5/1473 , A61B5/150022 , A61B5/150282 , A61B5/150419 , A61B5/150427 , A61B5/150435 , A61B5/150503 , A61B5/150984 , A61B5/6848 , A61B5/685 , A61B2017/00747 , A61M2037/0038 , A61M2037/0053 , B29C33/3857 , B29L2031/753 , B29L2031/7544
摘要： A method of forming an injection mold epidermal abrasion device includes depositing molded material on an epidermal abrasion device. The epidermal abrasion device is separated from the mold material to yield a mold (170). An epidermal abrasion device is then formed within the mold. The epidermal abrasion device may include a matrix of isotropically etched sidewalls positioned between wide bases and narrow tips, each isotropically etched structure having a vertical height of at least 20 microns. The matrix of isotropically etched structures may define a matrix of pyramids.
摘要翻译：形成注射模具表皮磨损装置的方法包括将成型材料沉积在表皮磨损装置上。将表皮磨损装置与模具材料分离以产生模具（170）。然后在模具内形成表皮磨损装置。表皮磨损装置可以包括位于宽基部和窄尖端之间的各向同性蚀刻的侧壁的基体，每个各向同性蚀刻的结构具有至少20微米的垂直高度。各向同性蚀刻结构的矩阵可以定义一个金字塔矩阵。

5. 发明申请

WO1994014240A1 MICROELECTROMECHANICAL SIGNAL PROCESSORS 审中-公开
标题翻译：微电子信号处理器
公开(公告)号：WO1994014240A1
公开(公告)日：1994-06-23
申请号：PCT/US1993011782
申请日：1993-12-10
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , LIN, Liwei , NGUYEN, Clark, Tu-Cuong , HOWE, Roger, T. , PISANO, Albert, P.
IPC分类号： H03H09/15
CPC分类号： H03H9/02275 , H03H9/02377 , H03H9/46 , H03H9/462
摘要： A micromechanical filter (30) having planar components, and manufacturable using very large scale integrated circuit microfabrication techniques. The input and output transducers are interdigitated comb electrodes (35). The mechanical coupling between the input and output transducers includes planar flexures (45), displacement of the electrodes producing bending of the elements (47, 48) of the flexures. By sealing micromechanical filters in a vacuum and providing on-board circuitry, high signal-to-noise ratios and quality factors are achievable. Construction of a real-time spectrum analyzer using many micromechanical resonators, provides a device with high accuracy and a short sample time.
摘要翻译：具有平面部件的微机械滤波器（30），并且可使用非常大规模的集成电路微加工技术制造。输入和输出换能器是叉指式梳状电极（35）。输入和输出换能器之间的机械耦合包括平面弯曲（45），电极的位移产生弯曲元件（47,48）的弯曲。通过在真空中密封微机械滤波器并提供板上电路，可以实现高信噪比和质量因素。构建使用许多微机械谐振器的实时频谱分析仪，为设备提供高精度和短的采样时间。

6. 发明申请

WO2009039193A1 CHITIN-BASED CANTILEVER BIMORPHS AND READOUT DEVICES 审中-公开
标题翻译：基于CHITIN的CANTILEVER BIMORPHS和READOUT设备
公开(公告)号：WO2009039193A1
公开(公告)日：2009-03-26
申请号：PCT/US2008/076705
申请日：2008-09-17
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , MUELLER, Michael, T. , PISANO, Albert, P. , AZEVEDO, Robert , WALTHER, David, C. , MYERS, David, R.
发明人： MUELLER, Michael, T. , PISANO, Albert, P. , AZEVEDO, Robert , WALTHER, David, C. , MYERS, David, R.
IPC分类号： G01J5/00
CPC分类号： G01J5/40
摘要： An infrared sensor with at least one cantilever beam functionalized with chitin, chitosan or their derivatives that can be tailored to be sensitive to certain IR bands for detection and does not require cooling is described. The functional layers expand differently than the structural layer of the cantilever beam causing the beam to bend in response to exposure to infrared radiation. The sensor can be adapted to optical, piezoresistive, capacitive and piezoelectric methods of detect beam deflection. Sensitivity can be increased with a reflective layer to increase the absorption of infrared radiation by the functional layer.
摘要翻译：一种红外传感器，其具有至少一个功能化的甲壳质，壳聚糖或其衍生物的悬臂梁，其可被定制为对某些IR带进行检测并且不需要冷却是敏感的。功能层与悬臂梁的结构层不同地膨胀，导致光束响应于暴露于红外辐射而弯曲。该传感器可适用于检测光束偏转的光学，压阻，电容和压电方法。可以用反射层增加灵敏度，以增加功能层对红外辐射的吸收。

7. 发明申请

WO2007056602A2 BONDING METALS AND NON-METALS USING INDUCTIVE HEATING 审中-公开
标题翻译：使用电感加热焊接金属和非金属
公开(公告)号：WO2007056602A2
公开(公告)日：2007-05-18
申请号：PCT/US2006/044019
申请日：2006-11-09
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , SOSNOWCHIK, Brian, D. , LIN, Liwei , PISANO, Albert, P.
发明人： SOSNOWCHIK, Brian, D. , LIN, Liwei , PISANO, Albert, P.
IPC分类号： H01L21/00 , H01L21/30
CPC分类号： B81C3/001 , B23K1/0016 , B23K1/002 , B23K1/203 , B23K2201/40 , B23K2203/08 , B23K2203/10 , B23K2203/12 , B23K2203/18 , B23K2203/26 , B23K2203/52 , B23K2203/54 , B23K2203/56 , G01L1/2293 , H01L24/29 , H01L24/83 , H01L2224/29111 , H01L2224/2919 , H01L2224/83222 , H01L2224/83801 , H01L2924/01005 , H01L2924/01006 , H01L2924/01013 , H01L2924/01015 , H01L2924/01024 , H01L2924/01029 , H01L2924/0103 , H01L2924/01033 , H01L2924/01047 , H01L2924/0105 , H01L2924/01074 , H01L2924/01075 , H01L2924/01077 , H01L2924/01079 , H01L2924/01082 , H01L2924/0132 , H01L2924/01322 , H01L2924/01327 , H01L2924/0133 , H01L2924/014 , H01L2924/0665 , H01L2924/09701 , H01L2924/10253 , H01L2924/30105 , H05B3/845 , H01L2924/00 , H01L2924/3512 , H01L2924/00014 , H01L2924/00012
摘要： A bonding technique suitable for bonding a non-metal body, such as a silicon MEMS sensor, to a metal surface, such a steel mechanical component is rapid enough to be compatible with typical manufacturing processes, and avoids any detrimental change in material properties of the metal surface arising from the bonding process. The bonding technique has many possible applications, including bonding of MEMS strain sensors to metal mechanical components. The inventive bonding technique uses inductive heating of a heat-activated bonding agent disposed between metal and non- metal objects to quickly and effectively bond the two without changing their material properties. Representative tests of silicon to steel bonding using this technique have demonstrated excellent bond strength without changing the steel's material properties. Thus, with this induction bonding approach, silicon MEMS devices can be manufacturably bonded to mechanical steel components for real time monitoring of the conditions/environment of a steel component.
摘要翻译：适用于将诸如硅MEMS传感器的非金属体接合到诸如钢机械部件的金属表面的接合技术足够快以与典型的制造工艺相容，并且避免了材料特性的任何有害变化金属表面产生的粘结过程。粘合技术具有许多可能的应用，包括将MEMS应变传感器结合到金属机械部件。本发明的粘合技术使用设置在金属和非金属物体之间的热激活粘合剂的感应加热来快速有效地粘合两者而不改变它们的材料性质。使用这种技术的硅到钢接合的代表性测试已经证明了优异的粘结强度，而不改变钢的材料性质。因此，通过这种感应焊接方法，硅MEMS器件可以可制造地结合到机械钢部件上，以实时监测钢部件的状况/环境。

8. 发明申请

WO2005001948A1 RADIAL BULK ANNULAR RESONATOR USING MEMS TECHNOLOGY 审中-公开
标题翻译：使用MEMS技术的径向散射环形谐振器
公开(公告)号：WO2005001948A1
公开(公告)日：2005-01-06
申请号：PCT/US2004/015967
申请日：2004-05-21
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , BIRCUMSHAW, Brian, L. , PISANO, Albert, P. , O'REILLY, Oliver, M.
发明人： BIRCUMSHAW, Brian, L. , PISANO, Albert, P. , O'REILLY, Oliver, M.
IPC分类号： H01L41/00
CPC分类号： H03H9/02259 , H03H3/0072 , H03H9/2436 , H03H2009/02503
摘要： A MEMS resonator includes an annular resonator body defined by an inner radius and an outer radius, a first electrode positioned within the inner radius and spaced from the resonator body, and a second electrode positioned around the annular resonator body and spaced from the outer radius. The first electrode and the second electrode provide for capacitive drive of the resonator body and capacitive sense of the resonator body. Piezo-resistive sense and piezoelectric drive/sense techniques can also be utilized. The overall extant can be smaller than 1 cm2 in area and positioned on a supporting substrate by a plurality of anchors. The substrate can comprise an RF transceiver integrated circuit with the anchors connecting the drive electrode and sense electrode to the integrated circuit. The resonator is readily fabricated using conventional semiconductor integrated circuit fabrication techniques.
摘要翻译： MEMS谐振器包括由内半径和外半径限定的环形谐振器主体，位于内半径内并与谐振器主体间隔开的第一电极，以及围绕环形谐振器本体并与外半径间隔开的第二电极。第一电极和第二电极提供谐振器体的电容驱动和谐振器本体的电容感。还可以使用压电感和压电驱动/感测技术。整个现场可以小于1平方厘米的面积，并通过多个锚点定位在支撑衬底上。基板可以包括RF收发器集成电路，其中锚定器将驱动电极和感测电极连接到集成电路。使用传统的半导体集成电路制造技术容易地制造谐振器。

9. 发明申请

WO2005057630A2 MANUFACTURABLE LOW-TEMPERATURE SILICON CARBIDE DEPOSITION TECHNOLOGY 审中-公开
标题翻译：可制造的低温硅碳化硅沉积技术
公开(公告)号：WO2005057630A2
公开(公告)日：2005-06-23
申请号：PCT/US2004/024728
申请日：2004-07-29
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , WIJESUNDARA, Mutha, B.J. , VALENTE, Gianluca , HOWE, Roger, T. , PISANO, Albert, P. , CARRARO, Carlo , MABOUDIAN, Roya
发明人： WIJESUNDARA, Mutha, B.J. , VALENTE, Gianluca , HOWE, Roger, T. , PISANO, Albert, P. , CARRARO, Carlo , MABOUDIAN, Roya
IPC分类号： H01L21/00
CPC分类号： C23C16/36 , C23C16/325 , C23C16/56 , H01L21/0237 , H01L21/02378 , H01L21/02381 , H01L21/0243 , H01L21/02529 , H01L21/02576 , H01L21/02609 , H01L21/0262
摘要： A method of depositing silicon carbide on a substrate, including placing a substrate in a low pressure chemical vapor deposition chamber; flowing a single source precursor gas containing silicon and carbon into the chamber; maintaining the chamber at a pressure not less than approximately 5 mTorr; and maintaining the substrate temperature less than approximately 900°C. The Method also includes a method for depositing a nitrogen doped silicon carbide by the addition of nitrogen containing gas into the chamber along with flowing a single source precursor gas containing silicon and carbon into the chamber.
摘要翻译：一种在基板上沉积碳化硅的方法，包括将基板放置在低压化学气相沉积室中; 将含有硅和碳的单一源前体气体流入室中; 将室保持在不小于约5mTorr的压力下; 并保持衬底温度低于约900℃。该方法还包括一种通过将含氮气体加入到室中来沉积氮掺杂碳化硅的方法，同时将含有硅和碳的单一源前体气体流入室中。

10. 发明申请

WO2003024311A2 A MICROFABRICATED SURGICAL DEVICE FOR INTERVENTIONAL PROCEDURES 审中-公开
标题翻译：用于传统程序的微波手术装置
公开(公告)号：WO2003024311A2
公开(公告)日：2003-03-27
申请号：PCT/US2002/029666
申请日：2002-09-20
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , SEWARD, Kirk, Patrick , PISANO, Albert, P.
发明人： SEWARD, Kirk, Patrick , PISANO, Albert, P.
IPC分类号： A61B
CPC分类号： A61B17/3478 , A61B2017/00247 , A61B2017/00345 , A61B2017/00398 , A61B2018/00392 , A61M2025/009 , A61M2025/1086
摘要： An actuator for an interventional surgical procedure is described. The actuator may include an actuator body having a distal end and a proximal end. A central expandable section is located between the distal end and the proximal end. The expandable section is operable between an unactuated condition in which the expandable section is in a furled state and an actuated condition in which the expandable section is in an unfurled state. A needle is located at the expandable section. The needle is moveable in an approximately perpendicular direction relative to a central longitudinal axis of the actuator body from a position within the actuator body to a position outside of the actuator body.
摘要翻译：描述了用于介入外科手术的致动器。致动器可以包括具有远端12f和近端12e的致动器本体。中心可扩张部分24位于远端12f和近端12e之间。可膨胀部分24可在可膨胀部分24处于卷曲状态的未致动状态和可膨胀部分24处于未展开状态的致动状态之间操作。针14位于可扩张部分。针14可以相对于致动器本体的中心纵向轴线在大致垂直的方向上从致动器本体内的位置移动到致动器主体外侧的位置。

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