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1. 发明申请

WO2009051804A1 THIAZOLIUM COMPOUNDS FOR TREATING OR PREVENTING DISEASES ASSOCIATED WITH INSULIN RESISTANCE 审中-公开
标题翻译：用于治疗或预防与胰岛素抵抗相关的疾病的噻唑化合物
公开(公告)号：WO2009051804A1
公开(公告)日：2009-04-23
申请号：PCT/US2008/011886
申请日：2008-10-17
申请人： SYNVISTA THERAPEUTICS, INC. , FORBES, Josephine , TONG, David , ANDRIKOPOULOS, Sofianos , COOPER, Mark
发明人： FORBES, Josephine , TONG, David , ANDRIKOPOULOS, Sofianos , COOPER, Mark
IPC分类号： A61K31/426 , A61K31/428 , A61P3/08 , A61P3/10
CPC分类号： A61K31/426 , A61K31/428
摘要： Thiazolium derivates for treating a patient having a metabolic disorder related to insulin resistance and/or beta cell dysfunction, including patients with type I diabetes, type II diabetes, metabolic syndrome and/or pre-diabetes.
摘要翻译：噻唑衍生物用于治疗与胰岛素抵抗和/或β细胞功能障碍相关的代谢紊乱患者，包括I型糖尿病，II型糖尿病，代谢综合征和/或前期糖尿病的患者。

2. 发明申请

WO2009006204A1 TRACK TRENCHER PROPULSION SYSTEM WITH LOAD CONTROL 审中-公开
标题翻译：带有负载控制的跟踪加速器推进系统
公开(公告)号：WO2009006204A1
公开(公告)日：2009-01-08
申请号：PCT/US2008/068355
申请日：2008-06-26
申请人： VERMEER MANUFACTURING COMPANY , HARTWICK, Ty , COOPER, Mark
发明人： HARTWICK, Ty , COOPER, Mark
IPC分类号： E02F5/14 , E02F9/20 , E02F9/22 , F16H61/46 , B60W30/18 , B60W10/10
CPC分类号： E02F5/145 , B62D11/003 , E02F9/2246 , E02F9/2253 , E02F9/26 , F16H61/465 , F16H2059/6861
摘要： A system and process for controlling propulsion and steering of a track trencher excavation machine (30) powered by an engine (36) includes a multiple mode propulsion and steering control system that performs a plurality of functions depending on a selection of one of a plurality of operational modes. A controller (182) generates a vehicle propulsion hydrostatic drive signal (318,319) using an engine speed (ERPM, 312) to determine a load multiplier (LM). The load multiplier (LM)' being defined as a function of the engine speed (ERPM) and an operator adjustable load control setting (380).
摘要翻译：用于控制由发动机（36）供电的履带挖掘机挖掘机（30）的推进和转向的系统和过程包括多模式推进和转向控制系统，其根据多个操作模式。控制器（182）使用发动机转速（ERPM，312）产生车辆推进静液压驱动信号（318,319）以确定负载倍增器（LM）。负载倍增器（LM）被定义为发动机转速（ERPM）和操作员可调负载控制设置（380）的函数。

3. 发明申请

WO2005000006A2 PLANT BREEDING METHOD 审中-公开
标题翻译：植物育种方法
公开(公告)号：WO2005000006A2
公开(公告)日：2005-01-06
申请号：PCT/US2004/016850
申请日：2004-05-27
申请人： PIONEER HI-BRED INTERNATIONAL, INC. , SMITH, Oscar, S. , COOPER, Mark , TINGEY, Scott, V. , RAFALSKI, Antoni, J. , LUEDTKE, Roy , NIEBUR, William, S.
发明人： SMITH, Oscar, S. , COOPER, Mark , TINGEY, Scott, V. , RAFALSKI, Antoni, J. , LUEDTKE, Roy , NIEBUR, William, S.
IPC分类号： A01H
CPC分类号： A01H1/04 , A01H1/02 , A01H5/10
摘要： Methods for using genetic marker genotype (e.g., gene sequence diversity information) to improve the process of developing plant varieties (e.g., single cross hybrids) with improved phenotypic performance are provided. Methods for predicting the value of a phenotypic trait in a plant are provided. The methods use genotypic, phenotypic, and optionally family relationship information for a first plant population to identify an association between at least one genetic marker and the phenotypic trait, and then use the association to predict the value of the phenotypic trait in one or more members of a second, target population of known marker genotype. Methods for identifying new allelic variants affecting the trait are also provided. Plants selected, provided, or produced by any of the methods herein, transgenic plants created by any of the methods herein, and digital systems for performing the methods herein are also provided.
摘要翻译：提供了使用遗传标记基因型（例如，基因序列多样性信息）来改进具有改进的表型性能的开发植物品种（例如，单杂交杂交）的过程的方法。提供了预测植物表型性状价值的方法。所述方法使用第一植物群体的基因型，表型和任选的家族关系信息来鉴定至少一个遗传标记和表型性状之间的关联，然后使用该关联来预测一个或多个成员中的表型性状的价值的第二个已知标记基因型的目标群体。还提供了确定影响性状的新的等位基因变异体的方法。本文中通过任何方法选择，提供或产生的植物，通过本文的任何方法产生的转基因植物和用于执行本文方法的数字系统也被提供。

4. 发明申请

WO2005014858A2 QTL "MAPPING AS-YOU-GO" 审中-公开
标题翻译： QTL“随地图绘制”
公开(公告)号：WO2005014858A2
公开(公告)日：2005-02-17
申请号：PCT/US2004/020167
申请日：2004-06-22
申请人： PIONEER HI-BRED INTERNATIONAL, INC. , PODLICH, Dean , COOPER, Mark , WINKLER, Christoph
发明人： PODLICH, Dean , COOPER, Mark , WINKLER, Christoph
IPC分类号： C12Q1/68
CPC分类号： C12Q1/68
摘要： This invention provides methods for monitoring QTL effects and marker assisted selection (MAS) involving providing a recursively determined correlation between one or more markers and a phenotype of interest.
摘要翻译：本发明提供了用于监测QTL效应和标记辅助选择（MAS）的方法，涉及提供一种或多种标记物与感兴趣表型之间递归确定的相关性。

5. 发明申请

WO2004106644A1 CYLINDRICAL CUTTING ELEMENT SUPPORTED ON A CHAIN 审中-公开
标题翻译：链条支撑的圆柱切割元件
公开(公告)号：WO2004106644A1
公开(公告)日：2004-12-09
申请号：PCT/US2004/015948
申请日：2004-05-21
申请人： VERMEER MANUFACTURING COMPANY , WHITTEN, Dean , HAWKS, Dan , COOPER, Mark
发明人： WHITTEN, Dean , HAWKS, Dan , COOPER, Mark
IPC分类号： E02F3/14
CPC分类号： E02F3/08 , E02F3/085 , E02F3/143 , E02F3/20 , E02F5/08 , E02F9/2866
摘要： In a chain excavator including an excavation chain (202) with links (14) routed around a drive sprocket (110) and an end idler (112) with a base plate (32) mounted to a link (14) for supporting excavation implements (20), a stabilizing element (32) extends rearwardly from directly behind the excavation implement (20) in order to contact and be supported by its trailing base plate (32).
摘要翻译：在链式挖掘机中，包括具有围绕驱动链轮（110）布置的连杆（14）的挖掘链（202）和具有安装到用于支撑挖掘工具的连杆（14）的底板（32）的端部惰轮（112） 20），稳定元件（32）从挖掘工具（20）的正后方向向后延伸，以便与其后底板（32）接触和支承。

6. 发明申请

WO2012030923A1 ENTERPRISE DATA DUPLICATION IDENTIFICATION 审中-公开
标题翻译：企业数据复制标识
公开(公告)号：WO2012030923A1
公开(公告)日：2012-03-08
申请号：PCT/US2011/049909
申请日：2011-08-31
申请人： FEDERAL EXPRESS CORPORATION , BRITTAIN, Brian , COOPER, Mark , YERRAMSETTY, Viswanath
发明人： BRITTAIN, Brian , COOPER, Mark , YERRAMSETTY, Viswanath
IPC分类号： G06F17/30
CPC分类号： G06F17/30489 , G06F17/30303
摘要： Systems, methods, and computer program products are provided for identifying duplicate data. In one exemplary embodiment, there is provided a method for identifying duplicate data. The method may include identifying one or more reference fields that include one or more data values. The method may include retrieving the one or more reference fields and one or more data values. The method may also include transforming the one or more reference fields into one or more reference fingerprint patterns. The method may also include identifying one or more target fields that include one or more target field values. The method may also include retrieving the one or more target fields. The method may also include transforming the one or more target field values into one or more target fingerprint patterns. The method may also include comparing the one or more reference fingerprint patterns with the one or more target fingerprint patterns. The method may further include determining an overlap between the one or more reference fingerprint patterns and the one or more target fingerprint patterns.
摘要翻译：系统，方法和计算机程序产品用于识别重复数据。在一个示例性实施例中，提供了一种用于识别重复数据的方法。该方法可以包括识别包括一个或多个数据值的一个或多个参考字段。该方法可以包括检索一个或多个参考字段和一个或多个数据值。该方法还可以包括将一个或多个参考字段变换为一个或多个参考指纹图案。该方法还可以包括识别包括一个或多个目标字段值的一个或多个目标字段。该方法还可以包括检索一个或多个目标字段。该方法还可以包括将一个或多个目标字段值变换成一个或多个目标指纹图案。该方法还可以包括将一个或多个参考指纹图案与一个或多个目标指纹图案进行比较。该方法还可以包括确定一个或多个参考指纹图案与一个或多个目标指纹图案之间的重叠。

7. 发明申请

WO2010063994A1 NON-SURGICAL IMPROVEMENT OF SCARS 审中-公开
标题翻译： SCARS非手术改善
公开(公告)号：WO2010063994A1
公开(公告)日：2010-06-10
申请号：PCT/GB2009/002790
申请日：2009-12-01
申请人： RENOVO LIMITED , FERGUSON, Mark, William, James , O'KANE, Sharon , COOPER, Mark , HUTCHINSON, John
发明人： FERGUSON, Mark, William, James , O'KANE, Sharon , COOPER, Mark , HUTCHINSON, John
IPC分类号： A61K38/18 , A61P17/02
CPC分类号： A61K38/1841
摘要： The present invention provides TGF-β3 for use as a medicament for provision to a scar to bring about the non-surgical improvement thereof. The medicaments may preferably be injectable medicaments. The invention also provides corresponding methods of treatment. A suitable amount of TGF-β3 to be provided may be between about 100 ng and 10,000 of TGF-β3 per centimetre of scar to be non-surgically improved, and is preferably about 500 ng or 1000 ng of TGF-β3 per centimetre of scar to be non-surgically improved. The scar to be improved may be a scar of the skin. Scars to be improved may be between 2 and 6 months post-wounding. Improvement using the medicaments or methods of the invention may reduce the redness and/or contrast of the scar.
摘要翻译：本发明提供TGF-β3用作用于提供瘢痕的药物以实现其非手术改善。药物可优选为可注射药物。本发明还提供相应的治疗方法。要提供的合适量的TGF-β3可以在约100ng-10,000之间的每厘米瘢痕中的TGF-β3是非手术改善的，并且优选为每厘米瘢痕约500ng或1000ng的TGF-β3 非手术改善。要改善的疤痕可能是皮肤的疤痕。有待改善的疤痕可能在伤后2至6个月之间。使用本发明的药物或方法的改进可以减少瘢痕的发红和/或对比。

8. 发明申请

WO2009132025A3 TRENCHER ATTACHMENT 审中-公开
公开(公告)号：WO2009132025A3
公开(公告)日：2009-10-29
申请号：PCT/US2009/041284
申请日：2009-04-21
申请人： VERMEER MANUFACTURING COMPANY , COOPER, Mark , HAWKS, Robert, Daniel , CUTLER, Edward, Lee
发明人： COOPER, Mark , HAWKS, Robert, Daniel , CUTLER, Edward, Lee
IPC分类号： E02F3/10 , E02F3/14 , E02F5/10 , E02D17/13 , E21C25/22
摘要： The present disclosure provides a system and method of creating trenches of various widths, including widths that are substantially greater than the width of the boom head (138) or even the chassis (12). According to the trencher system of the present disclosure, the boom (34, 42, 44) is designed so that it can be easily configured to create a trench of a first width and subsequently create a trench of a second width that is different than the first width.

9. 发明申请

WO2007016613A3 SLIDING AND ROTATING HINGE MODULE 审中-公开
公开(公告)号：WO2007016613A3
公开(公告)日：2007-02-08
申请号：PCT/US2006/030055
申请日：2006-08-01
申请人： Southco, Inc. , LOWRY, David, A. , COOPER, Mark
发明人： LOWRY, David, A. , COOPER, Mark
IPC分类号： E04G3/00
摘要： A sliding and rotating hinge module for supporting a display screen or the like, includes a bracket, a slider and a support member. The slider is capable of sliding movement relative to said bracket and said support member is capable of pivotal movement relative to said slider.

10. 发明申请

WO2011008694A2 SHEAR RESISTANT EXCAVATION COMPONENT 审中-公开
标题翻译：耐磨挖掘组件
公开(公告)号：WO2011008694A2
公开(公告)日：2011-01-20
申请号：PCT/US2010/041703
申请日：2010-07-12
申请人： VERMEER MANUFACTURING COMPANY , COOPER, Mark , DESCHAMP, Derrick , FLAHIVE, Jeff , HAWKS, Dan , MEINDERS, Glenn , VANDER HART, Michael
发明人： COOPER, Mark , DESCHAMP, Derrick , FLAHIVE, Jeff , HAWKS, Dan , MEINDERS, Glenn , VANDER HART, Michael
IPC分类号： E02F5/06 , E02F3/08 , B65G15/00 , E02F3/14 , E21C35/18
CPC分类号： E02F3/143 , E02F3/086 , E02F3/088 , E02F5/06
摘要： An excavation component is disclosed herein. The excavation component includes a cutter structure carrier and a cutter structure carried by the cutter structure carrier. The excavation component also includes a fastener for securing the cutter structure to the cutter structure carrier. The cutter structure carrier and the cutter structure have an interlocking geometry for transferring shear between the cutter structure carrier and the cutter structure so as to reduce an amount of shear applied to the fastener during excavation operations.
摘要翻译：本文公开了挖掘部件。挖掘部件包括切割器结构载体和由切割器结构载体承载的切割结构。挖掘部件还包括用于将切割器结构固定到切割器结构载体的紧固件。切割器结构载体和切割器结构具有用于在切割器结构载体和切割器结构之间传递剪切的互锁几何形状，以便减少在挖掘操作期间施加到紧固件的剪切量。

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