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1. 发明申请

WO2007070389A2 CONTROL OF PARASITIC WEEDS 审中-公开
标题翻译： PARASITIC WEEDS的控制
公开(公告)号：WO2007070389A2
公开(公告)日：2007-06-21
申请号：PCT/US2006/046926
申请日：2006-12-11
申请人： SYNGENTA PARTICIPATIONS AG , DEFRAMOND, Anic , HEIFETZ, Peter, B. , MCMILLAN, John
发明人： DEFRAMOND, Anic , HEIFETZ, Peter, B. , MCMILLAN, John
IPC分类号： A01H5/00
CPC分类号： C12N15/8279
摘要： The present invention provides methods for making plants resistant to parasitic weeds, the resistant transgenic plants, vectors and methods of integrated parasitic weed management.
摘要翻译：本发明提供了使植物抵抗寄生杂草，抗性转基因植物，载体和综合寄生杂草管理方法的方法。

2. 发明申请

WO2006013072A3 METHOD FOR ISOLATION OF TRANSCRIPTION TERMINATION SEQUENCES 审中-公开
公开(公告)号：WO2006013072A3
公开(公告)日：2006-02-09
申请号：PCT/EP2005/008285
申请日：2005-07-30
申请人： BASF Plant Science GmbH , SONG, Hee-Sook , KOCK, Michael , BROWN, Jeffrey A. , LOYALL, Linda Patricia , XING, Liqun , JIA, Hongmei , MCMILLAN, John , IRELAND, Lesley
发明人： SONG, Hee-Sook , KOCK, Michael , BROWN, Jeffrey A. , LOYALL, Linda Patricia , XING, Liqun , JIA, Hongmei , MCMILLAN, John , IRELAND, Lesley
IPC分类号： C12N15/10 , C12N15/82
摘要： The invention relates to efficient, high-throughput methods, systems, and DNA constructs for identification and isolation of transcription termination sequences. The invention relates further to specific terminator sequences identified by said methods isolated from rice.

3. 发明申请

WO2008152008A3 COMPOSITIONS AND METHODS OF USING RNA INTERFERENCE FOR CONTROL OF NEMATODES 审中-公开
公开(公告)号：WO2008152008A3
公开(公告)日：2008-12-18
申请号：PCT/EP2008/057132
申请日：2008-06-09
申请人： BASF PLANT SCIENCE GMBH , REN, Peifeng , CHAUDHURI, Sumita , TALTON, Lawrence Winfield , HUANG, Xiang , MCMILLAN, John
发明人： REN, Peifeng , CHAUDHURI, Sumita , TALTON, Lawrence Winfield , HUANG, Xiang , MCMILLAN, John
IPC分类号： C12N15/82 , C12N15/11 , A01H5/00
摘要： The present invention relates to the use of RNA interference to inhibit expression of plant parasitic nematode target let-70 genes, and relates to the generation of plants that have increased resistance to parasitic nematodes.

4. 发明申请

WO2007039454A1 METHODS FOR CONTROLLING GENE EXPRESSION USING TA-SIRAN 审中-公开
标题翻译：使用TA-SIRAN控制基因表达的方法
公开(公告)号：WO2007039454A1
公开(公告)日：2007-04-12
申请号：PCT/EP2006/066521
申请日：2006-09-20
申请人： BASF Plant Science GmbH , REN, Peifeng , SONG, Hee-Sook , WANG, Yuwen , MCMILLAN, John
发明人： REN, Peifeng , SONG, Hee-Sook , WANG, Yuwen , MCMILLAN, John
IPC分类号： C12N15/82
CPC分类号： C12N15/8218 , C12N15/8209 , C12N15/825 , C12N15/8261 , Y02A40/146
摘要： The present invention is in the field of genetics, especially plant genetics, and provides agents capable of controlling gene expression. More specifically the inventions relates to methods for engineering ta-siRNA primary transcripts in 5 order to target gene-of-interest (GOI) and control their expression. The invention further provides for a method for modulating transgenic expression by said engineered ta-siRNAs.
摘要翻译：本发明涉及遗传学，特别是植物遗传学领域，并提供能够控制基因表达的试剂。更具体地说，本发明涉及用于靶向感兴趣基因（GOI）并控制其表达的ta-siRNA初级转录物的方法。本发明进一步提供了通过所述工程化的ta-siRNA调节转基因表达的方法。

5. 发明申请

WO2011132127A1 ENHANCED METHODS FOR GENE REGULATION IN PLANTS 审中-公开
标题翻译：植物基因调控的增强方法
公开(公告)号：WO2011132127A1
公开(公告)日：2011-10-27
申请号：PCT/IB2011/051661
申请日：2011-04-18
申请人： BASF PLANT SCIENCE COMPANY GMBH , MCMILLAN, John , DIETZ, Jon , DEPPONG, Dave , REN, Peifeng , DIENER, Stephen , TALTON, Lawrence, Winfield , BASF (CHINA) COMPANY LIMITED
发明人： MCMILLAN, John , DIETZ, Jon , DEPPONG, Dave , REN, Peifeng , DIENER, Stephen , TALTON, Lawrence, Winfield
IPC分类号： C12N15/11 , C12N15/113 , C12N15/82 , C12N15/79 , A01H5/00 , A01H1/00
CPC分类号： C12N15/8218
摘要： The present invention is in the field of plant molecular biology and provides methods for regulating target gene expression in plants by suppression of the activity of endogenous small regulating RNAs targeting said target gene.
摘要翻译：本发明涉及植物分子生物学领域，并提供了通过抑制靶向所述靶基因的内源小调节RNA的活性来调节植物中靶基因表达的方法。

6. 发明申请

WO2007146325A2 MEDICAL DEVICE INTRODUCTION SYSTEMS AND METHODS 审中-公开
标题翻译：医疗器械引言系统与方法
公开(公告)号：WO2007146325A2
公开(公告)日：2007-12-21
申请号：PCT/US2007/013855
申请日：2007-06-13
申请人： OPTIVIA MEDICAL LLC , SNOKE, Phillip, Jack , MARTEL, Mark , MASSEY, MD, Joe, B. , FINCH, Marcus, E. , MCMILLAN, John , CASSIDY, Kenneth, Todd , ALLRED, Philip , WILSON, Jon, S. , ROTHSTEIN, Lawrence, B.
发明人： MASSEY, MD, Joe, B. , FINCH, Marcus, E. , MCMILLAN, John , CASSIDY, Kenneth, Todd , ALLRED, Philip , WILSON, Jon, S. , ROTHSTEIN, Lawrence, B.
IPC分类号： A61B1/005 , A61B1/018 , A61B1/303
CPC分类号： A61B1/303 , A61B1/00135 , A61B1/0051 , A61B1/018 , A61B1/07 , A61B17/42 , A61B2017/003
摘要： A medical device introduction system and method can include a medical introducer, a separate imaging device, and/or a separate working channel device, each of which may be movable independent of the other. The medical introducer can include a handle and an elongate introducer tube extending from the handle and having a plurality of lumens, and may be inserted into an interior body region of a patient. The separate imaging device may be inserted through the handle and positioned in one of lumens. The separate working channel device can include an elongate working channel tube and a position controller. The working channel tube can include at least one lumen defining a working channel. The position controller can be configured to control positioning of the working channel tube. The working channel device may be removably connected to the handle and positioned in another lumen.
摘要翻译：医疗器械引入系统和方法可以包括医疗引导器，分离的成像装置和/或单独的工作通道装置，每个工作通道装置可以彼此独立地移动。医疗引导器可以包括手柄和从手柄延伸并具有多个内腔的细长导引管，并且可插入到患者的内部身体区域中。分离的成像装置可以插入通过手柄并且定位在流明之一中。单独的工作通道装置可以包括细长工作通道管和位置控制器。工作通道管可以包括限定工作通道的至少一个内腔。位置控制器可以被配置为控制工作通道管的定位。工作通道装置可以可拆卸地连接到手柄并且定位在另一内腔中。

7. 发明申请

WO2006111512A1 IMPROVED METHODS CONTROLLING GENE EXPRESSION 审中-公开
标题翻译：改进的基因表达控制方法
公开(公告)号：WO2006111512A1
公开(公告)日：2006-10-26
申请号：PCT/EP2006/061604
申请日：2006-04-13
申请人： BASF PLANT SCIENCE GMBH , REN, Peifeng , SONG, Hee-Sook , MCMILLAN, John
发明人： REN, Peifeng , SONG, Hee-Sook , MCMILLAN, John
IPC分类号： C12N15/82 , C12N15/85 , C12N15/79 , A01H5/00
CPC分类号： C12N15/8218 , C12N15/79 , C12N15/8216
摘要： The present invention is in the field of genetics, especially plant genetics, and provides agents capable of controlling gene expression. The present invention specifically pro vides sequences of naturally occurring, tissue-specifically expressed microRNAs. The invention further provides for transgenic expression constructs comprising sequences encoding said microRNAs. By incorporation of the microRNA encoding sequence the expression from said expression construct is specifically silenced in the tissue where the naturally occurring microRNA is naturally expressed. Thereby the expression profile resulting from the promoter is modulated and leakiness is reduced. The invention fur ther provides for a method for modulating transgenic expression by incorporating se quences encoding said microRNAs into transgenic expression constructs. The compositions and methods of the invention can be used to enhance performance of agricul tural relevant crops and for therapy, prophylaxis, research and diagnostics in diseases and disorders, which afflict mammalian species.
摘要翻译：本发明涉及遗传学，特别是植物遗传学领域，并提供能够控制基因表达的试剂。本发明特别提供天然存在的组织特异性表达的微小RNA的序列。本发明还提供包含编码所述微小RNA的序列的转基因表达构建体。通过并入microRNA编码序列，所述表达构建体的表达在天然存在的微RNA天然表达的组织中被特异性沉默。因此，由启动子产生的表达谱被调节并且泄漏降低。本发明还提供了通过将编码所述微小RNA的序列并入转基因表达构建体来调节转基因表达的方法。本发明的组合物和方法可用于增强农业相关作物的性能，以及用于治疗，预防，研究和诊断哺乳动物物种的疾病和病症。

8. 发明申请

WO2010102300A1 LEADLESS ARRAY PLASTIC PACKAGE WITH VARIOUS IC PACKAGING CONFIGURATIONS 审中-公开
标题翻译：无铅阵列塑料包装与各种IC封装配置
公开(公告)号：WO2010102300A1
公开(公告)日：2010-09-10
申请号：PCT/US2010/026562
申请日：2010-03-08
申请人： ASAT LTD. , MCMILLAN, John , PEDRON, Serafin, P. , POWELL, Kirk , FUNG, Adonis
发明人： MCMILLAN, John , PEDRON, Serafin, P. , POWELL, Kirk , FUNG, Adonis
IPC分类号： H01L21/50
CPC分类号： H01L21/4832 , H01L21/565 , H01L23/3121 , H01L23/4952 , H01L23/49537 , H01L23/49541 , H01L23/49548 , H01L23/49575 , H01L23/49589 , H01L24/45 , H01L24/48 , H01L24/49 , H01L24/73 , H01L2224/05554 , H01L2224/16245 , H01L2224/29111 , H01L2224/2919 , H01L2224/32145 , H01L2224/32245 , H01L2224/45124 , H01L2224/45144 , H01L2224/45147 , H01L2224/48091 , H01L2224/48145 , H01L2224/48247 , H01L2224/48257 , H01L2224/49171 , H01L2224/49433 , H01L2224/73265 , H01L2225/06568 , H01L2924/01005 , H01L2924/01006 , H01L2924/01013 , H01L2924/01014 , H01L2924/01028 , H01L2924/01029 , H01L2924/01033 , H01L2924/01046 , H01L2924/01047 , H01L2924/0105 , H01L2924/01078 , H01L2924/01079 , H01L2924/01082 , H01L2924/0132 , H01L2924/01322 , H01L2924/014 , H01L2924/10329 , H01L2924/14 , H01L2924/1461 , H01L2924/181 , H01L2924/19041 , H01L2924/19105 , H01L2924/30107 , H01L2924/00014 , H01L2924/00 , H01L2924/00012 , H01L2924/0665
摘要： A leadless integrated circuit (IC) package comprising an IC chip mounted to a die- attach area and a plurality of electrical contacts electrically connected to the IC chip. The IC chip, the electrical contacts, and the die-attach area are all covered with a molding material, with portions of the electrical contacts and die-attach area protruding from a bottom surface of the molding material.
摘要翻译：一种无引线集成电路（IC）封装，包括安装到芯片附着区域的IC芯片和电连接到IC芯片的多个电触头。 IC芯片，电触点和芯片附着区域都被模制材料覆盖，其中部分电触头和芯片附着区域从模制材料的底表面突出。

9. 发明申请

WO2006020821A2 COMPOSITIONS AND METHODS USING RNA INTERFERENCE FOR CONTROL OF NEMATODES 审中-公开
标题翻译：使用RNA干扰控制线虫的组合物和方法
公开(公告)号：WO2006020821A2
公开(公告)日：2006-02-23
申请号：PCT/US2005/028657
申请日：2005-08-12
申请人： BASF PLANT SCIENCE GMBH , REN, Peifeng , HUANG, Xiang , CHAUDHURI, Sumita , TALTON, Lawrence , MCMILLAN, John
发明人： REN, Peifeng , HUANG, Xiang , CHAUDHURI, Sumita , TALTON, Lawrence , MCMILLAN, John
CPC分类号： C07K14/4354 , C12N15/8285 , Y02A40/164
摘要： The present invention concerns double stranded RNA compositions and transgenic plants capable of inhibiting expression of essential genes in parasitic nematodes, and methods associated therewith. Specifically, the invention relates to the use of RNA interference to inhibit expression of a target essential parasitic nematode gene, which is a parasitic nematode pas-5 gene, and relates to the generation of plants that have increased resistance to parasitic nematodes.
摘要翻译：本发明涉及能够抑制寄生线虫中必需基因表达的双链RNA组合物和转基因植物，以及与其相关的方法。具体而言，本发明涉及RNA干扰用于抑制作为寄生线虫pas-5基因的靶基本寄生线虫基因的表达，并且涉及对寄生线虫具有增加的抗性的植物的产生。 >

10. 发明申请

WO2005082932A2 COMPOSITIONS AND METHODS USING RNA INTERFERENCE FOR CONTROL OF NEMATODES 审中-公开
标题翻译：使用RNA干扰控制NEMATODES的组合物和方法
公开(公告)号：WO2005082932A2
公开(公告)日：2005-09-09
申请号：PCT/US2005/005756
申请日：2005-02-23
申请人： BASF PLANT SCIENCE GMBH , REN, Peifeng , HUANG, Xiang , CHAUDHURI, Sumita , TALTON, Lawrence , MCMILLAN, John
发明人： REN, Peifeng , HUANG, Xiang , CHAUDHURI, Sumita , TALTON, Lawrence , MCMILLAN, John
IPC分类号： C07K14/435
CPC分类号： C12N15/8218 , C12N15/8285 , Y02A40/164
摘要： The present invention concerns double stranded RNA compositions and transgenic plants capable of inhibiting expression of essential genes in parasitic nematodes, and methods associated therewith. Specifically, the invention relates to the use of RNA interference to inhibit expression of a target essential parasitic nematode gene selected from the group consisting of a parasitic nematode cytosolic chaperonin gene, a parasitic nematode gene encoding heat shock protein-90, a parasitic nematode gene homologous to the C. elegans Y65B4BR.5a gene, and a parasitic nematode gene homologous to a C. elegans pat-10 gene, and relates to the generation of plants that have increased tolerance to parasitic nematodes.
摘要翻译：本发明涉及能够抑制寄生线虫中必需基因表达的双链RNA组合物和转基因植物及其相关方法。具体地说，本发明涉及使用RNA干扰抑制靶寄生线虫基因的表达，该基因选自寄生线虫胞质伴侣蛋白基因，编码热休克蛋白90的寄生线虫基因，寄生线虫基因同源到线虫Y65B4BR.5a基因，以及与秀丽隐杆线虫pat-10基因同源的寄生线虫基因，涉及对寄生线虫具有增加的耐受性的植物的产生。

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