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    • 3. 发明申请
    • INSECTICIDAL COMPOUNDS
    • 杀虫剂化合物
    • WO2012163959A1
    • 2012-12-06
    • PCT/EP2012/060125
    • 2012-05-30
    • SYNGENTA PARTICIPATIONS AGCASSAYRE, Jérôme, YvesRENOLD, PeterEL QACEMI, MyriemPITTERNA, ThomasTOUEG, Julie, Clementine
    • CASSAYRE, Jérôme, YvesRENOLD, PeterEL QACEMI, MyriemPITTERNA, ThomasTOUEG, Julie, Clementine
    • C07D261/02C07D327/02A01N43/80
    • A01N43/80C07D261/02C07D327/02C07D411/12C07D413/12C07D413/14
    • The present invention provides compounds of formula (I): wherein A 1 , A 2 , A 3 and A 4 are independently of one another C-H, C-R 5 , or nitrogen; B 1 --B 2 --B 3 --B 4 is -CH 2 -C=N-CH 2 -, -CH 2 -N-CH 2 -CH 2 -, -CH 2 -C=CH-0- or -CH=C-CH 2 -0-; G 1 is oxygen or sulfur; L is a single bond or C 1 -C 8 alkylene; R 1 is hydrogen, C 1 -C 8 alkyl, C 1 -C 8 alkylcarbonyl-, C 1 -C 8 alkoxy, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl, C 1 -C 8 alkoxy- C 1 -C 8 alkyl, aryl or aryl substituted by one to three R 6 , or R 1 is heterocyclyl or heterocyclyl substituted by one to three R 6 or C 1 -C 8 alkoxycarbonyl-; R 2 is hydrogen, C 1 -C 8 haloalkyl or C 1 -C 8 alkyl; R 3 is C 1 -C 8 haloalkyl; R 4 is aryl or aryl substituted by one to three R 6 , or R 4 is heterocyclyl or heterocyclyl substituted by one to three R 6 ; Y 1 is CR 7 R 8 , C=O or C=S; Y 2 , Y 3 and Y 4 are independently CR 7 R 8 , C=0, C=S, N-R 9 , O, S, SO or SO 2 ; wherein at least two adjacent ring atoms in the ring formed by Y 1 , Y 2 , Y 3 and Y 4 are heteroatoms; each R 7 and R 8 is independently hydrogen, halogen, C 1 -C 8 alkyl, or C 1 -C 8 haloalkyl; and R 5 , R 6 , R 7 , R 8 and R 9 are as defined in the claims. The invention also relates to processes and intermediates for preparing these compounds, to insecticidal, acaricidal, nematicidal and molluscicidal compositions comprising these compounds and to methods of using these compounds to control insect, acarine, nematode and mollusc pests.
    • 本发明提供式(I)化合物:其中A1,A2,A3和A4彼此独立地为C-H,C-R5或氮; B1-B2-B3-B4是-CH2-C = N-CH2-,-CH2-N-CH2-CH2-,-CH2-C = CH-O-或-CH = C-CH2- ; G1是氧或硫; L是单键或C1-C8亚烷基; R 1是氢,C 1 -C 8烷基,C 1 -C 8烷基羰基 - ,C 1 -C 8烷氧基,C 2 -C 8链烯基,C 2 -C 8炔基,C 1 -C 8烷氧基-C 1 -C 8烷基,被1至3个R 6取代的芳基或芳基,或者R 1是杂环基或杂环基取代 一至三个R6或C1-C8烷氧基羰基 - ; R2是氢,C1-C8卤代烷基或C1-C8烷基; R3是C1-C8卤代烷基; R4是被一至三个R6取代的芳基或芳基,或R4是被一至三个R6取代的杂环基或杂环基; Y1是CR7R8,C = O或C = S; Y2,Y3和Y4独立地为CR7R8,C = 0,C = S,N-R9,O,S,SO或SO2; 其中由Y1,Y2,Y3和Y4形成的环中至少两个相邻的环原子是杂原子; 每个R 7和R 8独立地是氢,卤素,C 1 -C 8烷基或C 1 -C 8卤代烷基; 且R 5,R 6,R 7,R 8和R 9如权利要求中所定义。 本发明还涉及制备这些化合物的方法和中间体,包含这些化合物的杀虫,杀螨,杀线虫和杀软体动物的组合物,以及使用这些化合物来控制昆虫,螨虫,线虫和软体动物害虫的方法。
    • 10. 发明申请
    • DIHYDROPYRROLE DERIVATIVES AS INSECTICIDAL COMPOUNDS
    • 作为杀虫剂化合物的二氢衍生物衍生物
    • WO2013026929A1
    • 2013-02-28
    • PCT/EP2012/066550
    • 2012-08-24
    • SYNGENTA PARTICIPATIONS AGCASSAYRE, Jérôme YvesRENOLD, PeterPITTERNA, ThomasEL QACEMI, Myriem
    • CASSAYRE, Jérôme YvesRENOLD, PeterPITTERNA, ThomasEL QACEMI, Myriem
    • C07D409/12A01N43/36
    • C07D409/12
    • The present invention provides compounds of formula (I), wherein G 1 is oxygen; R 1 is hydrogen; R 2 is group P L is a bond, methylene or ethylene; one of A 1 and A 2 is S, SO or S0 2 and the other is -C(R 4 )R 4 - R 3 is hydrogen or methyl; each R 4 is independently hydrogen or methyl; Y 1 is C-R 6 , CH or nitrogen; Y 2 and Y 3 are independently CH or nitrogen; wherein no more than two of Y 1 , Y 2 and Y 3 are nitrogen and wherein Y 2 and Y 3 are not both nitrogen; R 5 is hydrogen, halogen, cyano, nitro, NH 2 , -C 2 alkyl, C 3 -C 2 haloalkyl, C 3 -C 5 cycloalkyl, C 3 - C 5 halocycloalkyl, C 1 -C 2 alkoxy, C 1 -C 2 haloalkoxy; R 6 together with R 5 forms a -CH=CH-CH=CH- bridge; X 2 is C-X 6 or nitrogen; X1, X 3 and X 6 are independently hydrogen, halogen or trihalomethyl, wherein at least two of X 1 , X 3 and X 6 are not hydrogen; X 4 is trifluoromethyl, difluoromethyl or chlorodifluoromethyl. The invention also provides intermediates useful for the preparation of compounds of formula I, as well as methods of controlling insects, acarines, nematodes or molluscs using the compounds of formula I.
    • 本发明提供式(I)化合物,其中G1是氧; R1是氢; R2是基团P L是键,亚甲基或亚乙基; A1和A2之一是S,SO或SO 2,另一个是-C(R 4)R 4 -R 3是氢或甲基; 每个R 4独立地是氢或甲基; Y1是C-R6,CH或氮; Y2和Y3独立地是CH或氮; 其中Y1,Y2和Y3中不超过两个是氮,并且其中Y2和Y3不都是氮; R5是氢,卤素,氰基,硝基,NH2,-C2烷基,C3-C2卤代烷基,C3-C5环烷基,C3-C5卤代环烷基,C1-C2烷氧基,C1-C2卤代烷氧基; R6与R5一起形成-CH = CH-CH = CH-桥; X2是C-X6或氮; X1,X3和X6独立地为氢,卤素或三卤代甲基,其中X 1,X 3和X 6中的至少两个不是氢; X4是三氟甲基,二氟甲基或氯二氟甲基。 本发明还提供了可用于制备式I化合物的中间体,以及使用式I化合物控制昆虫,螨虫,线虫或软体动物的方法。