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1. 发明申请

WO2014004654A1 APPARATUS AND METHOD FOR DELIVERING SURGICAL TISSUE CONNECTORS INTO AN ABDOMINAL CAVITY AND REMOVING THE SURGICAL TISSUE CONNECTORS FROM THE ABDOMINAL CAVITY 审中-公开
标题翻译：将外科组织连接器输送到腹腔并从腹部腔中移除手术组织连接器的装置和方法
公开(公告)号：WO2014004654A1
公开(公告)日：2014-01-03
申请号：PCT/US2013/047862
申请日：2013-06-26
申请人： SMITH, Jeff , SHERMAN, Darren, R.
发明人： SMITH, Jeff , SHERMAN, Darren, R.
IPC分类号： A61B17/04
CPC分类号： A61B17/105 , A61B17/00234 , A61B17/0218 , A61B17/0401 , A61B17/0469 , A61B17/08 , A61B17/10 , A61B2017/00362 , A61B2017/0409 , A61B2017/0411 , A61B2017/0414 , A61B2017/0446 , A61B2017/0464 , A61B2017/048 , A61B2017/0496
摘要： [0001] The present invention is directed to an apparatus and its method of use in delivering surgical tissue connectors into an area of the body and removing the surgical tissue connectors from the body area. Svlore specifically, the present invention is directed to a surgical tissue connector apparatus having at least two tissue connectors connected by a length of cord and a delivery and removai tube. At least one of the tissue connectors has a base with a tapered, beveled or chamfered surface projecting from one end of the base. A hook or other type of tissue connector projects from the opposite side of the base. The hook is positioned on the base where a peripheral side surface of the base shields the hook from unintentionally snagging objects. The base peripheral surface is also dimensioned to slide easily through an interior bore of the tube. This enables the base and the projecting hook to be easily delivered through the tube into an area of the body. The chamfered or tapered surface on the base is positioned to engage with the distal end opening of the tube and direct the base into the center of the tube as the surgical tissue connector is retracted info the tube from the body area in removing the apparatus from the abdominal cavity.
摘要翻译：本发明涉及一种用于将手术组织连接器递送到身体区域并从身体区域移除外科组织连接器的装置及其方法。特别地，本发明涉及一种外科组织连接器装置，其具有通过一段长度的线连接的至少两个组织连接器和递送和移除管。组织连接器中的至少一个具有从基部的一端突出的锥形，斜面或倒角表面的基部。钩或其他类型的组织连接器从基座的相对侧突出。钩子位于基座上，其中基部的外围侧表面遮蔽钩子以防止意外地阻塞物体。基座周边表面的尺寸也可以通过管的内孔容易地滑动。这使得底座和突出钩可以容易地通过管子输送到身体的区域中。基部上的倒角或锥形表面定位成与管的远端开口接合，并且当手术组织连接器缩回时将基部引导到管的中心，从而将管从身体区域中取出，从而将装置从腹腔

2. 发明申请

WO2008149331A2 VERIFYING AUTHENTICITY OF WEBPAGES 审中-公开
标题翻译：验证声明
公开(公告)号：WO2008149331A2
公开(公告)日：2008-12-11
申请号：PCT/IB2008/053482
申请日：2008-06-05
申请人： ALCATEL LUCENT , CHOW, Stanley , SMITH, Jeff , GUSTAVE, Christophe
发明人： CHOW, Stanley , SMITH, Jeff , GUSTAVE, Christophe
CPC分类号： H04L63/0823 , H04L63/12 , H04L63/168
摘要： A certificate registry system is configured to issue authentication certificates issued to each one of a plurality of information providers and to maintain a root certificate corresponding to all of the authentication certificates. Each one of the authentication certificates links respective authentication information thereof to identification information of a corresponding one of the information providers. Each one of the authentication certificates is devoid of linkage between the corresponding one of the information providers and domain name information thereof. The authentication certificates of the certificate registry are associated in a manner at least partially dependent upon at least one of a particular type of information that the information providers provide, a particular organization that the information providers are associated with, a particular type profession in which the information providers are engaged and a particular geographical region in which the information providers are located.
摘要翻译：证书注册系统被配置为发出颁发给多个信息提供者中的每一个的认证证书并维护与所有认证证书相对应的根证书。每个认证证书将其相应的认证信息链接到相应的一个信息提供者的识别信息。认证证书中的每一个都没有相应的一个信息提供者和其域名信息之间的链接。证书注册管理机构的认证证书至少部分地取决于信息提供者提供的特定类型的信息，信息提供者所关联的特定组织，特定类型职业中的至少一个，其中信息提供者参与信息提供者所在的特定地理区域。

3. 发明申请

WO2011159951A2 TARGETING TUMOR ASSOCIATED MACROPHAGES USING BISPHOSPHONATE-LOADED PARTICLES 审中-公开
标题翻译：使用二磷酸酯加载的颗粒靶向肿瘤相关巨噬细胞
公开(公告)号：WO2011159951A2
公开(公告)日：2011-12-22
申请号：PCT/US2011/040776
申请日：2011-06-16
申请人： SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE , SMITH, Jeff , SHARMA, Gaurav
发明人： SMITH, Jeff , SHARMA, Gaurav
IPC分类号： A61K31/663
CPC分类号： A61K31/663 , A61K9/5138 , A61K47/62 , A61K47/6937 , B82Y5/00
摘要： Provided herein are compositions including particles that comprise a bisphosphonate compound and a tumor specific targeting peptide or peptidomimetic. Also provided herein are methods of reducing tumor associated macrophages and methods of treating cancer with said compositions.
摘要翻译：本文提供了包含包含双膦酸盐化合物和肿瘤特异性靶向肽或肽模拟物的颗粒的组合物。本文还提供了减少肿瘤相关巨噬细胞的方法和用所述组合物治疗癌症的方法。

4. 发明申请

WO2008149328A2 VERIFYING AUTHENTICITY OF E-MAIL MESSAGES 审中-公开
标题翻译：验证电子邮件信息的正确性
公开(公告)号：WO2008149328A2
公开(公告)日：2008-12-11
申请号：PCT/IB2008/053475
申请日：2008-06-05
申请人： ALCATEL LUCENT , CHOW, Stanley , SMITH, Jeff , GUSTAVE, Christophe
发明人： CHOW, Stanley , SMITH, Jeff , GUSTAVE, Christophe
CPC分类号： H04L63/126 , H04L51/12 , H04L63/0823
摘要： A certificate registry system configured to issue authentication certificates to each one of a plurality of information providers and to maintain a root certificate corresponding to all of the authentication certificates, wherein each one of the authentication certificates links respective authentication information thereof to identification information of a corresponding one of the information providers, wherein each one of the authentication certificates is devoid of linkage between the corresponding one of the information providers and e-mail address information thereof, and wherein the authentication certificates of the certificate registry are associated in a manner at least partially dependent upon at least one of a particular type of information that the information providers provide, a particular organization that the information providers are associated with, a particular type profession in which the information providers are engaged and a particular geographical region in which the information providers are located.
摘要翻译：一种证书注册系统，被配置为向多个信息提供者中的每一个提供认证证书，并维护与所有认证证书相对应的根证书，其中每个认证证书将其相应认证信息链接到相应的认证证书的识别信息信息提供者之一，其中每个认证证书中没有相应的一个信息提供者和其电子邮件地址信息之间的链接，并且其中证书注册表的认证证书以至少部分的方式相关联取决于信息提供者提供的特定类型的信息中的至少一种，信息提供者所关联的特定组织，信息提供者所参与的特定类型的职业以及特定的地理区域信息提供者所在的位置。

5. 发明申请

WO2007127199A1 NATURAL ORIFICE SURGICAL SYSTEM 审中-公开
标题翻译：自然手术手术系统
公开(公告)号：WO2007127199A1
公开(公告)日：2007-11-08
申请号：PCT/US2007/009936
申请日：2007-04-24
申请人： SYNECOR, LLC , GLENN, Richard, A. , WILLIAMS, Michael, S. , FIFIER, Daniel, W. , STACK, Richard, S. , SMITH, Jeff , ORTH, Geoffrey
发明人： GLENN, Richard, A. , WILLIAMS, Michael, S. , FIFIER, Daniel, W. , STACK, Richard, S. , SMITH, Jeff , ORTH, Geoffrey
IPC分类号： A61B1/018 , A61B17/34
CPC分类号： A61B1/018 , A61B1/00052 , A61B1/00128 , A61B1/00135 , A61B17/0218 , A61B17/29 , A61B17/3403 , A61B17/3421 , A61B90/50 , A61B2017/00278 , A61B2017/003 , A61B2017/2905 , A61B2017/2906 , A61B2017/3407 , A61B2017/3445 , A61B2017/3447 , A61B2017/3486 , A61B2090/372
摘要： A system for performing minimally invasive medical procedures through a natural orifice includes an elongate support advanceable in a flexible state through a natural orifice and through an incision in a body organ into a body cavity. The elongate support is convertible to a rigid state within the body cavity. The elongate support supports a frame that carries a pair of tool cannulas, each of which has a lumen for receiving a tool useable to perform a procedure in the body cavity. The frame is expandable to orient the tool cannulas such that they allow the tools to be used in concert to carry out a procedure at a common location in the body cavity.
摘要翻译：用于通过自然孔进行微创医疗程序的系统包括细长支撑件，其可以通过自然孔口以柔性状态前进，并且通过身体器官中的切口进入体腔。细长的支撑可转换成体腔内的刚性状态。细长的支撑件支撑着一个承载一对工具插管的框架，每个工具插管都具有用于接收可用于在体腔中执行过程的工具的内腔。框架是可扩展的以使工具插管定向，使得它们允许工具一起使用以在体腔中的共同位置执行过程。

6. 发明申请

WO2004094261A1 HOT FILL BOTTLE 审中-公开
标题翻译：热水瓶
公开(公告)号：WO2004094261A1
公开(公告)日：2004-11-04
申请号：PCT/GB2004/001518
申请日：2004-04-08
申请人： CADBURY SCHWEPPES PTY LTD , WARD, David, I. , SMITH, Jeff
发明人： SMITH, Jeff
IPC分类号： B65D79/00
CPC分类号： B65D79/005 , B65D1/0223 , B65D2501/0036
摘要： The present invention discloses a hot fill bottle (10) of polymeric material having a plurality of thermal expansion panels equally spaced around a peripheral wall of the bottle and three dimensional logos embossed into the peripheral wall of the bottle. The three dimensional logos constitute, at least in part, the thermal expansion panels. Thus, instead of the thermal expansion panels contributing to an unsightly component of the bottle that needs to be covered up by a label, it is now possible to make the thermal expansion panel double as an eye catching logo.
摘要翻译：本发明公开了一种聚合材料的热填充瓶（10），其具有围绕瓶的周边壁等间隔开的多个热膨胀面板以及压花到瓶的周壁中的三维标志。至少部分地，三维标志构成热膨胀面板。因此，代替对需要被标签覆盖的瓶子的难看的部件有助于热膨胀面板，现在可以使热膨胀面板成为醒目的标志的两倍。

7. 发明申请

WO2007038715A1 TRANSGASTRIC SURGICAL DEVICES AND PROCEDURES 审中-公开
标题翻译：转移性外科手术和手术
公开(公告)号：WO2007038715A1
公开(公告)日：2007-04-05
申请号：PCT/US2006/037978
申请日：2006-09-27
申请人： SYNECOR, LLC , WILLIAMS, Michael, S. , STACK, Richard, S. , ORTH, Geoff , SMITH, Jeff , GLENN, Richard, A. , ATHAS, William, S. , PRYOR, Aurora
发明人： WILLIAMS, Michael, S. , STACK, Richard, S. , ORTH, Geoff , SMITH, Jeff , GLENN, Richard, A. , ATHAS, William, S. , PRYOR, Aurora
IPC分类号： A61B17/34
CPC分类号： A61B17/3421 , A61B17/0057 , A61B17/3417 , A61B17/3423 , A61B17/3478 , A61B17/3496 , A61B46/10 , A61B90/40 , A61B2017/00278 , A61B2017/00867 , A61B2017/00871 , A61B2017/3484 , A61B2017/3486 , A61B2017/3488 , A61B2017/349 , A61B2017/3492
摘要： Embodiments of surgical access cannulas and access systems for use in gaining access to a body cavity of a patient via a natural orifice are disclosed. A distal end of an access cannula is advanced through a natural orifice into a hollow organ. Instruments passed through the cannula are used to form an incision in the wall of the hollow organ. The access cannula is anchored in the incision with its distal opening giving access to a body cavity outside the hollow organ. Surgical instruments are passed through the access cannula and used to perform procedures in the body cavity.
摘要翻译：公开了用于通过自然孔口进入患者体腔的外科手术插管和进入系统的实施例。进入插管的远端通过自然孔进入中空器官。通过插管的仪器用于在中空器官的壁上形成切口。进入插管锚定在切口中，其远端开口进入中空器官外部的体腔。手术器械通过入口插管并用于在体腔中执行程序。

8. 发明申请

WO2005018095A2 SYSTEM AND METHOD FOR AUTO SENSING AND PROVISIONING TWO OR FOUR WIRE MODE ON A COMMUNICATIONS LINE WITH RATE ADAPTATION 审中-公开
标题翻译：用于自动感测和在具有速率适应性的通信线上提供两条或四条线路的方法的系统和方法
公开(公告)号：WO2005018095A2
公开(公告)日：2005-02-24
申请号：PCT/IB2004/002649
申请日：2004-08-14
申请人： COVARO NETWORKS, INC. , SMITH, Jeff , MEZEUL, Michael Joseph , JAMIESON, Ross Alexander
发明人： SMITH, Jeff , MEZEUL, Michael Joseph , JAMIESON, Ross Alexander
IPC分类号： H04B
CPC分类号： H04M3/308 , H04M3/2209
摘要： A system and method for sensing and provisioning two or four wire mode for a communications link are provided. In one example, the method includes attempting to train a base wire pair associated with a base port for two-wire mode. If the two-wire mode training is unsuccessful, an unassigned port associated with a first wire pair is identified and the base and unassigned ports are configured for four-wire mode. An attempt is made to train the base and first wire pairs for four-wire mode. If the four-wire mode training is successful, a four-wire service is established using the base and first wire pairs.
摘要翻译：提供了一种用于感测和提供用于通信链路的两线或四线模式的系统和方法。在一个示例中，该方法包括尝试训练与用于两线模式的基本端口相关联的基线对。如果双线模式训练不成功，则识别与第一对线对应的未分配端口，并将基本和未分配端口配置为四线模式。尝试对四线模式的基线和第一线对进行训练。如果四线模式训练成功，则使用基线和第一线对建立四线服务。

9. 发明申请

WO2013033255A2 LIGHTING MODULE HAVING A COMMON TERMINAL 审中-公开
标题翻译：照明模块具有通用端子
公开(公告)号：WO2013033255A2
公开(公告)日：2013-03-07
申请号：PCT/US2012/052917
申请日：2012-08-29
申请人： PHOSEON TECHNOLOGY, INC. , BASAURI, Alejandro V. , SMITH, Jeff
发明人： BASAURI, Alejandro V. , SMITH, Jeff
IPC分类号： F21V29/00 , F21V21/002
CPC分类号： F21V23/00 , F21K9/00 , F21V19/0055 , F21V29/70 , F21V29/763 , F21Y2105/10 , F21Y2115/10 , H01L2224/32225 , H01L2224/48091 , H01L2224/48465 , H01L2224/73265 , H05K1/021 , H05K2201/10106 , H01L2924/00014 , H01L2924/00
摘要： A lighting module has an electrically conductive heat sink, an array of light-emitting elements mounted on and electrically connected to the conductive heat sink, a flex circuit mounted on the conductive sink, and conductive traces on the flex circuit, the conductive traces connected to the light-emitting elements. A lighting module has a heat sink, an array of light-emitting elements, each element having a cathode terminal and an anode terminal, wherein the heat sink is a common terminal for the elements.
摘要翻译：发光模块具有导电散热器，安装在导电散热器上并与导电散热器电连接的发光元件阵列，安装在导电散热器上的柔性电路以及在导电散热器上的导电迹线柔性电路，导电迹线连接到发光元件。照明模块具有散热器，发光元件阵列，每个元件具有阴极端子和阳极端子，其中散热器是元件的公共端子。

10. 发明申请

WO2011050105A1 COMPOSITIONS OF NANOPARTICLES AND METHODS OF MAKING THE SAME 审中-公开
标题翻译：纳米颗粒的组成及其制备方法
公开(公告)号：WO2011050105A1
公开(公告)日：2011-04-28
申请号：PCT/US2010/053436
申请日：2010-10-20
申请人： SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE , SMITH, Jeff , XIE, Hui
发明人： SMITH, Jeff , XIE, Hui
IPC分类号： B01F3/08 , B82B1/00
CPC分类号： A61K47/30 , A61K9/5153 , A61K9/5192 , A61K31/00 , A61K31/337 , A61K31/704 , A61K45/06 , A61K47/34 , B01F3/0807 , B01F5/0471 , B01F5/0475 , B01F5/048 , B01F13/0059 , B82Y5/00 , A61K2300/00
摘要： Disclosed herein are compositions of nanoparticles. In some embodiments, the nanoparticles are Janus particles, where each particle includes a first component and second component that are exposed to the surface of the particle. Also, disclosed are methods and systems for making a composition of nanoparticles. Finally, a method of treating a mammal by administering a composition of nanoparticles is disclosed.
摘要翻译：本文公开了纳米颗粒的组合物。在一些实施方案中，纳米颗粒是Janus颗粒，其中每个颗粒包括暴露于颗粒表面的第一组分和第二组分。还公开了制备纳米颗粒组合物的方法和系统。最后，公开了一种通过施用纳米颗粒组合物来治疗哺乳动物的方法。

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