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1. 发明申请

WO2011089601A1 TRICUSPID VALVE REPAIR USING TENSION 审中-公开
标题翻译：三角阀维修使用张力
公开(公告)号：WO2011089601A1
公开(公告)日：2011-07-28
申请号：PCT/IL2011/000064
申请日：2011-01-20
申请人： 4TECH SA , MAISANO, Francesco , VANERMEN, Hugo , PEREVALOV, Valery , HOF, Rephael , ALFIERI, Ottavio , TOBIS, Idan
发明人： MAISANO, Francesco , VANERMEN, Hugo , PEREVALOV, Valery , HOF, Rephael , ALFIERI, Ottavio , TOBIS, Idan
IPC分类号： A61F2/06
CPC分类号： A61F2/2454 , A61B17/0401 , A61B17/064 , A61B17/068 , A61B2017/00243 , A61B2017/00407 , A61B2017/0409 , A61B2017/0412 , A61B2017/0414 , A61B2017/0437 , A61B2017/0441 , A61B2017/0443 , A61B2017/0464 , A61B2017/048 , A61B2017/0488 , A61B2017/0496 , A61B2017/0649 , A61F2/2442 , A61F2/2457 , A61F2/246 , A61F2/2487 , A61F2/848 , A61F2/90 , A61F2/915 , A61F2002/8483 , A61F2002/8486 , A61F2220/0008 , A61F2220/0016 , A61F2230/0013 , A61F2230/0054
摘要： A method is provided, including implanting at least a first tissue-engaging element (60a) in a first portion of tissue in a vicinity of a heart valve (4) of a patient, implanting at least a second tissue-engaging element (60b) in a portion of a blood vessel (8, 10) that is in contact with an atrium (6) of a heart (2) of the patient, and drawing at least a first leaflet of the valve (4) toward at least a second leaflet of the valve (4) by adjusting a distance between the portion of the blood vessel (8, 10) and the first portion of tissue in the vicinity of the heart valve (4) of the patient. Other applications are also described.
摘要翻译：提供了一种方法，包括将至少第一组织接合元件（60a）植入在患者的心脏瓣膜（4）附近的组织的第一部分中，至少植入第二组织接合元件（60b）在与患者的心脏（2）的心房（6）接触的血管（8,10）的一部分中，并且至少将所述阀（4）的第一小叶拉至至少第二个通过调节血管（8,10）的部分与患者心脏瓣膜（4）附近的组织的第一部分之间的距离来调节瓣膜（4）的小叶。还描述了其它应用。

2. 发明申请

WO2010083103A1 SYNTHETIC CHORD 审中-公开
标题翻译：合成词
公开(公告)号：WO2010083103A1
公开(公告)日：2010-07-22
申请号：PCT/US2010/020464
申请日：2010-01-08
申请人： SYMBICORE, LLC. , LONGORIA, James
发明人： LONGORIA, James
IPC分类号： A61B17/04
CPC分类号： A61F2/2463 , A61B17/0401 , A61B17/06166 , A61B2017/00243 , A61B2017/00783 , A61B2017/00862 , A61B2017/00867 , A61B2017/0406 , A61B2017/0427 , A61B2017/048 , A61B2017/06057 , A61F2/2457 , A61F2250/0064
摘要： Synthetic chord devices and methods for using the same for connecting tissues are provided. Aspects of the synthetic chord device include a flexible cord having an attachment element at both a first and a second end, wherein each attachment element includes a piercing member coupled to a securing member that attaches the flexible cord to a first tissue. At least a portion of the flexible cord can be configured to be secured to a second tissue. Aspects of the invention also include sets of the synthetic chord device with pre-measured flexible cords. The devices and methods of the invention find use in a variety of applications, such as in applications in which it is desired to repair a heart valve.
摘要翻译：提供合成和弦装置及其组合使用方法。合成弦装置的方面包括在第一和第二端处具有附接元件的柔性绳，其中每个附接元件包括联接到将柔性绳连接到第一组织的固定构件的刺穿构件。软线的至少一部分可被构造成固定到第二组织。本发明的方面还包括具有预先测量的柔性绳的合成弦装置的组合。本发明的装置和方法可用于各种应用中，例如在期望修复心脏瓣膜的应用中。

3. 发明申请

WO2009064994A1 MITRAL SPACER 审中-公开
标题翻译：麻药间隔
公开(公告)号：WO2009064994A1
公开(公告)日：2009-05-22
申请号：PCT/US2008/083570
申请日：2008-11-14
申请人： CARDIOSOLUTIONS, INC. , MAURER, Christopher William , WILSON, Jonathan Edward
发明人： MAURER, Christopher William , WILSON, Jonathan Edward
IPC分类号： A61F2/82
CPC分类号： A61F2/246 , A61B2017/00243 , A61B2017/0441 , A61B2017/048
摘要： A heart valve implant may include a shaft and an anchor configured to be coupled to an end of the shaft. A spacer may be coupled to a portion of the shaft and comprise a first segment coupled to the shaft and at least a second coupled to at least a portion of an exterior surface of the first segment. The second segment may have at least one cross-section dimension greater than an internal cross-sectional dimension of a delivery lumen. Additional segments may be coupled to an inner, adjacent segment. The segments may include a collapsible body portion to facilitate percutaneously delivery through a lumen and may define an outer surface of the spacer configured to interact with at least a portion of at least one cusp of a heart valve to at least partially restrict a flow of blood through the heart valve in a closed position.
摘要翻译：心脏瓣膜植入物可以包括轴和锚，其被构造成联接到轴的端部。间隔件可以联接到轴的一部分并且包括联接到轴的第一段和耦合到第一段的外表面的至少一部分的至少一个第二段。第二段可以具有大于输送腔的内部横截面尺寸的至少一个横截面尺寸。附加段可以耦合到内部相邻段。所述段可以包括可折叠的主体部分，以便于经由内腔的经皮输送，并且可以限定所述间隔件的外表面，其被配置为与心脏瓣膜的至少一个尖瓣的至少一部分相互作用以至少部分地限制血流通过心脏瓣膜处于闭合位置。

4. 发明申请

WO2009051682A1 DEVICES, METHODS, AND TOOLS FOR EFFECTING HEART VALVE TREATMENT 审中-公开
标题翻译：用于治疗心脏瓣膜治疗的装置，方法和工具
公开(公告)号：WO2009051682A1
公开(公告)日：2009-04-23
申请号：PCT/US2008/011696
申请日：2008-10-14
申请人： MYOCOR, INC. , VIDLUND, Robert, M. , EKVALL, Craig, A. , SCHROEDER, Richard, F. , SCHWEICH, Cyril, J., Jr. , MORTIER, Todd, J. , WESTON, Matthew, W. , BRODEUR, Christopher, B. , MATTHES, Edward, J. , SEGNER, Garland, L. , LAPLANTE, Jeffrey, P.
发明人： VIDLUND, Robert, M. , EKVALL, Craig, A. , SCHROEDER, Richard, F. , SCHWEICH, Cyril, J., Jr. , MORTIER, Todd, J. , WESTON, Matthew, W. , BRODEUR, Christopher, B. , MATTHES, Edward, J. , SEGNER, Garland, L. , LAPLANTE, Jeffrey, P.
IPC分类号： A61F2/24
CPC分类号： A61B17/0401 , A61B2017/00243 , A61B2017/0409 , A61B2017/048 , A61F2/2487
摘要： Devices and methods for improving the function of a valve, such as, for example, a mitral valve.
摘要翻译：用于改善瓣膜功能的装置和方法，例如二尖瓣。

5. 发明申请

WO2008154033A2 CARDIAC PATTERNING FOR IMPROVING DIASTOLIC FUNCTION 审中-公开
标题翻译：用于改善脱脂功能的CARDIAC图案
公开(公告)号：WO2008154033A2
公开(公告)日：2008-12-18
申请号：PCT/US2008/007351
申请日：2008-06-11
申请人： SYMPHONY MEDICAL, INC. , SABBAH, Hani, N. , LEE, Randall, J. , HINSON, Andrew, G.
发明人： SABBAH, Hani, N. , LEE, Randall, J. , HINSON, Andrew, G.
IPC分类号： A61N1/36
CPC分类号： A61F2/2478 , A61B17/00491 , A61B17/12022 , A61B17/12045 , A61B17/12122 , A61B17/12136 , A61B17/12181 , A61B17/12186 , A61B17/1219 , A61B2017/00243 , A61B2017/048 , A61B2017/1205 , A61B2017/12127 , A61F2/2481 , A61F2002/249 , A61F2250/0067 , A61L31/005
摘要： Cardiomyopathy may be treated by distributing a space-occupying diastole- assist agent within the myocardium or within the cardiac venous system in a pattern about one or more chambers of the heart, such that the space- modifying agent integrates into and thickens at least part of the cardiac wall about the chamber so as globally to reduce wall stress, stabilize or even reduce chamber size, and/or improve diastolic function. Some patterns also cause a beneficial global reshaping of the chamber. These changes occur quickly and are sustainable, and have a rapid and sustainable therapeutic effect on cardiac function. Patterns of distribution of space-occupying agent within the myocardium for global resizing may also be used or augmented to treat localized conditions such as myocardial infarctions, overt aneurysm of the ventricular wall as typically forms in response to large transmural myocardial infarctions, and mitral regurgitation due to a noncompliant mitral valve. These techniques may also be used to treat localized conditions that may not yet have progressed to cardiomyopathy.
摘要翻译：心肌病可以通过以围绕心脏的一个或多个腔室的模式在心肌内或心脏静脉系统内分布空间占据舒张辅助剂来治疗，使得空间改变剂整合入并增稠至少部分围绕腔室的心脏壁，以便全局地减小壁应力，稳定或甚至减小腔室尺寸，和/或改善舒张功能。一些模式也引起了对室的有益的全局整形。这些变化迅速发生并且是可持续的，并且对心脏功能具有快速和可持续的治疗作用。用于全局调整大小的心肌内空间占位剂的分布模式也可以被使用或增加以治疗局部的情况，例如心肌梗死，通常形成为响应于大的透壁性心肌梗死的室壁的明显的动脉瘤和二尖瓣反流到不合规的二尖瓣。这些技术也可用于治疗可能尚未进展为心肌病的局部病症。

6. 发明申请

WO2008006084A3 LOW PROFILE TISSUE ANCHORS, TISSUE ANCHOR SYSTEMS, AND METHODS FOR THEIR DELIVERY AND USE 审中-公开
标题翻译：低剖面组织锚固件，组织锚固系统及其输送和使用方法
公开(公告)号：WO2008006084A3
公开(公告)日：2008-12-04
申请号：PCT/US2007072984
申请日：2007-07-06
申请人： USGI MEDICAL INC , EWERS RICHARD C , MAAHS TRACY D , VONG SHIRLEY
发明人： EWERS RICHARD C , MAAHS TRACY D , VONG SHIRLEY
IPC分类号： A61B17/08
CPC分类号： A61B17/0401 , A61B17/0487 , A61B17/06166 , A61B17/22031 , A61B17/282 , A61B17/29 , A61B2017/00004 , A61B2017/00526 , A61B2017/00862 , A61B2017/00986 , A61B2017/0403 , A61B2017/0409 , A61B2017/0417 , A61B2017/0451 , A61B2017/0458 , A61B2017/048 , A61B2017/0496 , A61B2017/061
摘要： Tissue anchors include a flat, broad, and large contact surface for engagement with a portion of tissue. Several embodiments of composite tissue anchors include a support element and an overlay element. Tissue anchor assemblies include two or more tissue anchors, a connector, and a cinching mechanism. In some embodiments, the tissue anchors included in the tissue anchor assemblies are of different types, sizes, and/or shapes.
摘要翻译：组织锚固件包括平坦的，宽的和大的接触表面，用于与一部分组织接合。复合组织锚的几个实施例包括支撑元件和覆盖元件。组织锚组件包括两个或多个组织锚，连接器和收紧机构。在一些实施例中，包括在组织锚组件中的组织锚固件具有不同类型，尺寸和/或形状。

7. 发明申请

WO2008112740A2 SYSTEMS AND METHODS FOR INTRODUCING ELEMENTS INTO TISSUE 审中-公开
标题翻译：将元素引入组织的系统和方法
公开(公告)号：WO2008112740A2
公开(公告)日：2008-09-18
申请号：PCT/US2008/056620
申请日：2008-03-12
申请人： MITRALIGN, INC. , BAIM, Donald, S. , CAHALANE, Steven, D. , CALL, Aaron, M. , HOLMES, Megan, E. , LANE, Joseph, P. , LEE, Christopher, C. , MCNAMARA, Edward, I. , MAGUIRE, Mark , MORRILL, Richard, J. , ROBINSON, Jason, H. , SPENCE, Paul, A. , SUGIMOTO, Hiroatsu , TRAYNOR, Kate, E.
发明人： BAIM, Donald, S. , CAHALANE, Steven, D. , CALL, Aaron, M. , HOLMES, Megan, E. , LANE, Joseph, P. , LEE, Christopher, C. , MCNAMARA, Edward, I. , MAGUIRE, Mark , MORRILL, Richard, J. , ROBINSON, Jason, H. , SPENCE, Paul, A. , SUGIMOTO, Hiroatsu , TRAYNOR, Kate, E.
IPC分类号： A61F2/02
CPC分类号： A61F2/2466 , A61B17/00234 , A61B17/0057 , A61B17/0401 , A61B17/0467 , A61B17/0469 , A61B17/0487 , A61B17/06166 , A61B90/39 , A61B2017/00243 , A61B2017/00637 , A61B2017/00659 , A61B2017/0411 , A61B2017/0417 , A61B2017/0419 , A61B2017/0464 , A61B2017/048 , A61B2017/0488 , A61B2017/0496 , A61B2017/0619 , A61B2090/0811 , A61B2090/3966 , A61F2/2427 , A61F2/2442 , A61F2/2445
摘要： Systems, devices and methods for securing tissue including the annulus (40) of a mitral valve (20). The systems, devices and methods may employ catheter based techniques and devices to plicate annulus tissue (40) and perform an annuloplasty.
摘要翻译：用于固定包括二尖瓣（20）的环（40）的组织的系统，装置和方法。系统，装置和方法可以使用基于导管的技术和装置来折叠环形组织（40）并执行瓣环成形术。

8. 发明申请

WO2008008889A2 ANNULOPLASTY SYSTEM AND SURGICAL METHOD 审中-公开
标题翻译： ANNULOPLASTY系统和手术方法
公开(公告)号：WO2008008889A2
公开(公告)日：2008-01-17
申请号：PCT/US2007/073356
申请日：2007-07-12
申请人： KHALAPYAN, Tigran
发明人： KHALAPYAN, Tigran
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61B17/0401 , A61B17/0467 , A61B2017/00783 , A61B2017/0406 , A61B2017/0456 , A61B2017/0458 , A61B2017/0464 , A61B2017/0472 , A61B2017/048 , A61B2017/0496
摘要： An annuloplasty system for repairing incompetent heart valves is provided. This system includes a substantially circular valve reinforcing device adapted to be surgically implanted into around a heart valve annulus; anchoring means for attaching the substantially circular valve reinforcing device to the heart valve, wherein attaching the substantially circular valve reinforcing device to the heart valve annulus reduces the circumference of the heart valve annulus by plicating annular tissue underneath the valve reinforcing device; and constricting means for, if necessary, reducing the circumference of the substantially circular valve reinforcing device, wherein reducing the circumference of the substantially circular valve reinforcing device further reduces the circumference of the heart valve annulus.
摘要翻译：提供了用于修复不合格心脏瓣膜的瓣环成形术系统。该系统包括适于外科植入心脏瓣膜环周围的基本上圆形的瓣膜增强装置; 其中将所述基本上圆形的瓣膜增强装置附接到所述心脏瓣膜环上通过将所述瓣膜增强装置下方的环形组织折叠来减小所述心脏瓣膜瓣环的周长; 和收缩装置，用于在必要时减小大致圆形的瓣膜增强装置的周边，其中减小大致圆形的瓣膜增强装置的周长进一步减小心脏瓣膜瓣环的周长。

9. 发明申请

WO2008006084A2 LOW PROFILE TISSUE ANCHORS, TISSUE ANCHOR SYSTEMS, AND METHODS FOR THEIR DELIVERY AND USE 审中-公开
标题翻译：低剖面组织锚，组织锚固系统及其递送和使用方法
公开(公告)号：WO2008006084A2
公开(公告)日：2008-01-10
申请号：PCT/US2007/072984
申请日：2007-07-06
申请人： USGI MEDICAL, INC. , EWERS, Richard C. , MAAHS, Tracy D. , VONG, Shirley
发明人： EWERS, Richard C. , MAAHS, Tracy D. , VONG, Shirley
IPC分类号： A61B17/03
CPC分类号： A61B17/0401 , A61B17/0487 , A61B17/06166 , A61B17/22031 , A61B17/282 , A61B17/29 , A61B2017/00004 , A61B2017/00526 , A61B2017/00862 , A61B2017/00986 , A61B2017/0403 , A61B2017/0409 , A61B2017/0417 , A61B2017/0451 , A61B2017/0458 , A61B2017/048 , A61B2017/0496 , A61B2017/061
摘要： Tissue anchors include a flat, broad, and large contact surface for engagement with a portion of tissue. Several embodiments of composite tissue anchors include a support element and an overlay element. Tissue anchor assemblies include two or more tissue anchors, a connector, and a cinching mechanism. In some embodiments, the tissue anchors included in the tissue anchor assemblies are of different types, sizes, and/or shapes.
摘要翻译：组织锚定器包括用于与一部分组织接合的扁平，宽且大的接触表面。复合组织锚固件的若干实施例包括支撑元件和覆盖元件。组织锚定组件包括两个或更多个组织锚定器，连接器和收紧机构。在一些实施例中，包含在组织锚定件组件中的组织锚定件具有不同的类型，尺寸和/或形状。

10. 发明申请

WO2007022519A3 STEERABLE HEART IMPLANTS FOR CONGESTIVE HEART FAILURE 审中-公开
标题翻译：可控心脏植入物用于心脏失效
公开(公告)号：WO2007022519A3
公开(公告)日：2007-05-03
申请号：PCT/US2006032663
申请日：2006-08-21
申请人： CHF TECHNOLOGIES INC , ANNEST LON S , BERTOLERO ARTHUR A , CHIN SING-FATT , SWANSON DAVID K
发明人： ANNEST LON S , BERTOLERO ARTHUR A , CHIN SING-FATT , SWANSON DAVID K
IPC分类号： A61B19/00
CPC分类号： A61F2/2487 , A61B17/00234 , A61B17/0401 , A61B17/0467 , A61B17/0487 , A61B17/08 , A61B2017/00022 , A61B2017/00044 , A61B2017/00247 , A61B2017/003 , A61B2017/00867 , A61B2017/00893 , A61B2017/00986 , A61B2017/0412 , A61B2017/0417 , A61B2017/0462 , A61B2017/0464 , A61B2017/048 , A61B2017/0496 , A61B2017/06052 , A61B2017/06176 , A61B2017/22054 , A61B2017/22069 , A61B2018/00392
摘要： Devices, systems, and methods for treating a heart of a patient may make use of one or more implant structures which limit a size of a chamber of the heart, such as by deploying a tensile member to bring a wall of the heart toward (optionally into contact with) a septum of the heart.
摘要翻译：用于治疗患者心脏的装置，系统和方法可以利用限制心脏室的尺寸的一个或多个植入物结构，例如通过展开拉伸构件以使心脏的壁朝向（任选地接触）心脏隔膜。

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