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1. 发明申请

WO2019091877A1 INJECTION DEVICE WITH A DOSE LIMITER 审中-公开
公开(公告)号：WO2019091877A1
公开(公告)日：2019-05-16
申请号：PCT/EP2018/080076
申请日：2018-11-05
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： HELMER, Michael , SCHABBACH, Michael , JUGL, Michael , NOBER, Peter , KEIM, Moritz , RAU, Matthias
IPC分类号： A61M5/315
摘要： The present disclosure relates to an injection device for setting and injecting a dose of a medicament, the injection device comprising: - an elongated housing (10) extending along an axial direction (z) and configured to accommodate a dose setting mechanism (9), wherein the housing (10) comprises a sidewall (43; 143) with at least a first fastening feature (41; 141) - a dose dial (12) rotatable relative to the housing (10) for setting of a dose, - a dose tracker (50) arranged inside the housing (10) and operably connectable to the dose dial (12), the dose tracker (50) comprises at least one tracking stop feature (51), wherein the dose tracker (50) is one of translationally or rotationally displaceable relative to the housing (10) during setting of a dose and wherein a positional state of the dose tracker (50) relative to the housing (10) is indicative of a size of the dose, and - a limiter (70; 170) attachable to the sidewall (43; 143) of the housing (10) from outside the housing (10) and engageable with the at least first fastening feature (41, 41), wherein the limiter (70; 170) comprises at least one limiter stop feature (71; 171) extending inwardly from the sidewall (43; 143) when the limiter (70; 170) is attached to the sidewall (43), wherein the limiter stop feature (71; 171) and the tracking stop feature (51) are configured to mutually engage and to block a displacement of the dose tracker (50) beyond a predefined maximum dose positional state.

2. 发明申请

WO2019091878A1 INJECTION DEVICE WITH A PRESELECTOR 审中-公开
公开(公告)号：WO2019091878A1
公开(公告)日：2019-05-16
申请号：PCT/EP2018/080077
申请日：2018-11-05
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： HELMER, Michael , JUGL, Michael , SCHABBACH, Michael , RAU, Matthias , KERSTING, Julian , THURNES, Andrea
IPC分类号： A61M5/315
CPC分类号： A61M5/31536 , A61M5/20 , A61M5/31551 , A61M5/3156 , A61M5/31586 , A61M2005/3154
摘要： The present disclosure relates to an injection device for setting and injecting a dose of a medicament, the injection device comprising: - an elongated housing (10) extending along a longitudinal axis (z) and having a distal end (41) and a proximal end (42), a dose tracker (50; 150; 250; 350; 450; 550) being at least one of translationally or rotationally displaceable relative to the housing (10) and being displaceable between a zero dose positional state (52) and a maximum dose positional (54) state relative to the housing (10) for setting of the dose, wherein the positional state (52, 54) of the dose tracker (50; 150) relative to the housing (10) is indicative of a size of the dose, wherein one of the elongated housing (10) and the dose tracker (50; 150; 250; 350; 450) comprises at least one tracking stop feature (51; 151; 251; 351; 451; 551 ), a preselector (70; 170; 270; 370; 470; 570) displaceable relative to the housing (10) between at least two preselection positional states (72, 74) thereby defining the maximum dose positional state (54) of the dose tracker (50; 150; 250; 350; 450; 550), wherein the preselector (17; 170; 270; 370; 470; 570) comprises at least one preselector stop feature (71; 171; 271; 371; 471 ) configured to mechanically engage with the at least one tracking stop feature (51; 151; 251; 351; 551 ) to block a displacement of the dose tracker (50; 150; 250; 350; 450; 550) beyond the maximum dose positional state (54).

3. 发明申请

WO2018166985A1 DRUG DELIVERY DEVICE 审中-公开
公开(公告)号：WO2018166985A1
公开(公告)日：2018-09-20
申请号：PCT/EP2018/056111
申请日：2018-03-12
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： DASBACH, Uwe , SCHADER, Marc , KNEIP, Michael , RAU, Matthias , NOBER, Peter
IPC分类号： A61M5/20
摘要： The present disclosure relates to a drug delivery device (1), having a longitudinal axis (L) and comprising a plunger (10) movable along the longitudinal axis (L) and a guide curve (2.18) adapted to engage at least one part (10.2, 10.2, 10.3) of the plunger (10) so as to guide the plunger (10) when the plunger (10) is being released to move along the longitudinal axis (L).

4. 发明申请

WO2018082886A1 FEEDBACK MECHANISM FOR AN INJECTION DEVICE 审中-公开
标题翻译：注射装置的反馈机构
公开(公告)号：WO2018082886A1
公开(公告)日：2018-05-11
申请号：PCT/EP2017/076048
申请日：2017-10-12
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： BAUMEYER, Martin , NOBER, Peter , RAU, Matthias , HUTHMACHER, Winfried , JANIAK, Markus
IPC分类号： A61M5/315
摘要： The present invention relates to a feedback mechanism (20) for an injection device that is configured to deliver a medicament to a user. The feedback mechanism (20) has a biasing member that is arranged to apply a force to a delay element (30), and the delay element (30) is configured to deform and/or break under the force. The feedback mechanism (20) also includes an indicator (24) arranged to generate user feedback after the delay element (30) is deformed and/or broken. The delay element (30) is configured to deform and/or break at a time after the force is applied by the biasing member to create a delay before the user feedback is generated.
摘要翻译：本发明涉及一种用于注射装置的反馈机构（20），该注射装置构造成向使用者递送药剂。所述反馈机构（20）具有偏置构件，所述偏置构件被布置成向延迟元件（30）施加力，并且所述延迟元件（30）被构造成在所述力的作用下变形和/或断裂。反馈机构（20）还包括布置成在延迟元件（30）变形和/或破坏之后产生用户反馈的指示器（24）。延迟元件（30）被配置成在偏置构件施加力之后的一段时间变形和/或断开，以在产生用户反馈之前产生延迟。

5. 发明申请

WO2018141993A1 ASSEMBLY NEST FOR A PEN INJECTION DEVICE WITH LOCKING FUNCTION 审中-公开
公开(公告)号：WO2018141993A1
公开(公告)日：2018-08-09
申请号：PCT/EP2018/052973
申请日：2018-02-06
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： RAU, Matthias , HUTHMACHER, Winfried , BRAUN, Sebastian , SCHADER, Marc , JANIAK, Markus , KNEIP, Michael , BAUMEYER, Martin , NOBER, Peter
IPC分类号： A61M5/00 , F16B1/00 , F16G11/10 , A61M5/31 , B65B5/08 , A61M5/32 , B65B19/00 , B65D85/20
摘要： The present invention relates to an assembly nest for transporting a tubular sub assembly of a drug delivery device on an automated production line, wherein the tubular sub assembly comprises a tubular body and a cap that is wider than the tubular body. The assembly nest comprises a base against which a sub assembly of a drug delivery device is mountable to orientate said sub assembly in a predetermined position; and a locking mechanism having a resilient member to urge the locking mechanism into one of: an unlocked position, in which a sub assembly of a drug delivery device can be mounted to the base; or a locked position, in which the locking mechanism engages a mounted sub assembly to retain it in its predetermined position on the base.

6. 发明申请

WO2018104204A1 A CAP FOR AN INJECTION DEVICE 审中-公开
公开(公告)号：WO2018104204A1
公开(公告)日：2018-06-14
申请号：PCT/EP2017/081310
申请日：2017-12-04
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： NOBER, Peter , RAU, Matthias , THEYSEN, David
IPC分类号： A61M5/32
摘要： The present invention relates to cap (21) for an injection device (20). The cap (21) comprises a needle shield (22) and a conduit (31). The needle shield (22) comprises a body (24) with a recess (25) for receiving part of a needle syringe (18). The conduit (31) is movable from an initial position, wherein a portion of the body (24) is located between the recess (25) and the conduit (31), to a cap removal position, wherein the conduit (31) extends through said portion of the body (24) to fluidly communicate with the recess (25) to allow the ingress of gas into the recess (25).

7. 发明申请

WO2018104203A1 AN INJECTION DEVICE 审中-公开
公开(公告)号：WO2018104203A1
公开(公告)日：2018-06-14
申请号：PCT/EP2017/081309
申请日：2017-12-04
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： NOBER, Peter , RAU, Matthias , THEYSEN, David
IPC分类号： A61M5/32 , A61M5/20
摘要： The present invention relates to an injection device (20). The injection device (20) comprises a housing (11) for holding a syringe (18) that has a needle (17) at one end and a cap (21) that is removably attached to the housing (11) and has a needle shield (22) to cover said needle (17). The cap (21) further comprises an actuator (27) and a gear assembly (26) comprising first and second linear gears (28, 29) and a double gear (30). The gear assembly (26) is configured such that movement of the first linear gear (28) in a first direction rotates the double gear (30) to drive the second linear gear (29) to urge the needle shield (22) away from the housing (11). The actuator (27) is configured to move the first linear gear (28) in the first direction.

8. 发明申请

WO2018082891A1 FEEDBACK MECHANISM FOR AN INJECTION DEVICE 审中-公开
标题翻译：注射装置的反馈机构
公开(公告)号：WO2018082891A1
公开(公告)日：2018-05-11
申请号：PCT/EP2017/076097
申请日：2017-10-12
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： SCHADER, Marc , RAU, Matthias , BRAUN, Sebastian
IPC分类号： A61M5/145 , A61M5/168 , A61M5/20 , A61M5/315
摘要： The present invention relates to a feedback mechanism for an injection device (20) that is configured to deliver a medicament to a user. The feedback mechanism comprises an actuator (27) and a fluid chamber (40) having a restricted outlet (42). The actuator (27) is adapted to urge fluid from the fluid chamber (40) through the restricted outlet (42). The feedback mechanism also has an indicator (43) that is adapted to provide feedback to the user after a predetermined volume of fluid has passed from the fluid chamber (40) through the restricted outlet (42) during use of the injection device (20).
摘要翻译：本发明涉及一种用于注射装置（20）的反馈机构，该注射装置（20）被构造成将药剂递送给使用者。反馈机构包括致动器（27）和具有受限出口（42）的流体腔室（40）。致动器（27）适于促使来自流体腔室（40）的流体通过受限出口（42）。反馈机构还具有指示器（43），该指示器适于在使用注射装置（20）期间预定体积的流体从流体腔室（40）通过限制出口（42）之后向用户提供反馈，

9. 发明申请

WO2018082887A1 FEEDBACK MECHANISM FOR AN INJECTION DEVICE 审中-公开
标题翻译：注射装置的反馈机构
公开(公告)号：WO2018082887A1
公开(公告)日：2018-05-11
申请号：PCT/EP2017/076056
申请日：2017-10-12
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： SCHADER, Marc , KNEIP, Michael , RAU, Matthias
IPC分类号： A61M5/145 , A61M5/168 , A61M5/20 , A61M5/315
摘要： The present invention relates to a feedback mechanism for an injection device (20) that is configured to deliver a medicament to a user. The feedback mechanism comprises a piston (24) and a fluid chamber (25), and the piston (24) is adapted to move into the fluid chamber (25) during use of the injection device (20). The feedback mechanism also has a damper (28, 34) that is arranged to damp movement of the piston (24), and an indicator (33) that is arranged to provide feedback to the user after the piston (24) has moved a pre-determined distance into the fluid chamber (25).
摘要翻译：本发明涉及一种用于注射装置（20）的反馈机构，该注射装置（20）被构造成将药剂递送给使用者。反馈机构包括活塞（24）和流体室（25），并且活塞（24）适于在注射装置（20）的使用期间移动到流体室（25）中。反馈机构还具有布置成阻尼活塞（24）的运动的阻尼器（28,34）以及布置成在活塞（24）已经移动预先提供的位置之后向用户提供反馈的指示器（33） - 确定进入流体室（25）的距离。

10. 发明申请

WO2018011253A1 AN INJECTION NEEDLE ASSEMBLY 审中-公开
标题翻译：注射针头组件
公开(公告)号：WO2018011253A1
公开(公告)日：2018-01-18
申请号：PCT/EP2017/067507
申请日：2017-07-12
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： HELMER, Michael , RAU, Matthias , HUTHMACHER, Winfried
IPC分类号： A61M5/24 , A61M5/50 , A61M5/32 , A61B5/15 , A61M5/158 , A61M5/162 , A61M39/10
CPC分类号： A61M5/3245 , A61M5/2466 , A61M5/3202 , A61M5/3213 , A61M5/3243 , A61M5/50 , A61M5/5086 , A61M39/04 , A61M2005/247 , A61M2005/3254 , A61M2039/0205 , A61M2039/1072 , A61M2205/0216 , A61M2207/00
摘要： The present invention relates to an injection needle assembly (16, 116, 216, 316, 416) for use in a medicament delivery device (10). The injection needle assembly comprises an injection needle holder (27), an injection needle (17) fixed to said injection needle holder (27), the injection needle (17) having a proximal end (18) and a distal end (19), and a sealing assembly (25) for sealing the distal end (19) of the injection needle (17). The sealing assembly (25) comprises a spacer element (31) surrounding the distal end (19) of the injection needle (17) and a sealing membrane (32) for sealing the distal end (19) of the injection needle (17).
摘要翻译：本发明涉及一种用于药物输送装置（10）的注射针组件（16,116,216,316,416）。注射针组件包括注射针保持器27，固定到所述注射针保持器27的注射针17，注射针17具有近端18和远端19，和用于密封注射针（17）的远端（19）的密封组件（25）。密封组件（25）包括围绕注射针（17）的远端（19）的隔离元件（31）和用于密封注射针（17）的远端（19）的密封膜（32）。

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