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1. 发明申请

WO2009002621A3 MEDICAL DIAGNOSIS, THERAPY, AND PROGNOSIS SYSTEM FOR INVOKED EVENTS AND METHOD THEREOF 审中-公开
标题翻译：用于被调查事件的医学诊断，治疗和预测系统及其方法
公开(公告)号：WO2009002621A3
公开(公告)日：2008-12-31
申请号：PCT/US2008/063395
申请日：2008-05-12
申请人： ROCHE DIAGNOSTICS GMBH , F. HOFFMAN-LA ROCHE AG , THUKRAL, Ajay , GALLEY, Paul , CHITTAJALLU, Siva
发明人： THUKRAL, Ajay , GALLEY, Paul , CHITTAJALLU, Siva
IPC分类号： G06F19/00
摘要： A diagnosis, therapy and prognosis system (DTPS) and method thereof to help either the healthcare provider or the patient in diagnosing, treating and interpreting data are disclosed. The apparatus provides data collection based on protocols, and mechanism for testing data integrity and accuracy. The data is then driven through an analysis engine to characterize in a quantitative sense the metabolic state of the patient's body. The characterization is then used in diagnosing the patient, determining therapy, evaluating algorithm strategies and offering prognosis of potential use case scenarios.
摘要翻译：公开了一种诊断，治疗和预后系统（DTPS）及其方法，以帮助医疗保健提供者或患者诊断，治疗和解释数据。该设备提供基于协议的数据收集，以及用于测试数据完整性和准确性的机制。然后通过分析引擎驱动数据以定量表征患者身体的代谢状态。然后将表征用于诊断患者，确定疗法，评估算法策略并提供潜在用例情景的预测。

2. 发明申请

WO2009002620A1 SYSTEM AND METHOD FOR DEVELOPING PATIENT SPECIFIC THERAPIES BASED ON MODELING OF PATIENT PHYSIOLOGY 审中-公开
标题翻译：基于患者生理学建模的患者特异性治疗的系统与方法
公开(公告)号：WO2009002620A1
公开(公告)日：2008-12-31
申请号：PCT/US2008/063394
申请日：2008-05-12
申请人： F. HOFFMAN-LA ROCHE AG , ROCHE DIAGNOSTICS GMBH , THUKRAL, Ajay , GALLEY, Paul , CHITTAJALLU, Siva , WEINERT, Stefan
发明人： THUKRAL, Ajay , GALLEY, Paul , CHITTAJALLU, Siva , WEINERT, Stefan
IPC分类号： G06F19/00
CPC分类号： G06F19/3437 , A61M5/1723 , A61M2005/14296 , G06F19/00 , G06F19/325 , G06F19/3456 , G06F19/3468 , G06F19/3475 , G06F19/3481 , G06F19/36 , G16H10/20 , G16H50/20 , G16H50/50
摘要： A system for developing patient-specific therapies based on dynamic modeling of patient-specific physiology and method thereof are disclosed. The system includes software modules configured to provide access via a computer to data collection protocols defining at least a type of patient-specific data to be collected and a manner in which the patient-specific data is to be collected, and to information from which patient- specific models, configured to simulate aspects of the patient's physiology, are developed. Another software module of the system is configured to provide access via the computer to software tools that apply patient-specific data, collected according to data collection protocols, to patient specific models to determine therefrom patient- specific therapies.
摘要翻译：公开了一种基于患者特异性生理学的动态建模及其方法开发患者特异性疗法的系统。该系统包括被配置为提供通过计算机访问数据收集协议的软件模块，该数据收集协议定义要收集的至少一种类型的患者特定数据和要收集患者特定数据的方式，以及定义哪个患者 - 具体模型，配置为模拟患者生理学的方面，被开发。该系统的另一个软件模块被配置为提供通过计算机访问的软件工具，其将根据数据收集协议收集的患者特定数据应用于患者特定模型，从而确定患者特异性治疗。

3. 发明申请

WO2009002627A1 THERAPY DELIVERY SYSTEM HAVING AN OPEN ARCHITECTURE AND A METHOD THEREOF 审中-公开
标题翻译：具有开放式结构的治疗方法及其方法
公开(公告)号：WO2009002627A1
公开(公告)日：2008-12-31
申请号：PCT/US2008/063696
申请日：2008-05-15
申请人： ROCHE DIAGNOSTICS OPERATIONS, INC. , F. HOFFMAN-LA ROCHE AG , WEINERT, Stefan , THUKRAL, Ajay , GALLEY, Paul , CHITTAJALLU, Siva , BOUSAMRA, Steven , LONG, James
发明人： WEINERT, Stefan , THUKRAL, Ajay , GALLEY, Paul , CHITTAJALLU, Siva , BOUSAMRA, Steven , LONG, James
IPC分类号： G06F19/00
CPC分类号： G06F19/3456 , G06F19/00 , G16H50/50
摘要： A therapy delivery system having an open architecture and method of providing thereof are disclosed. The present invention provides a therapy dosage module having a control algorithm that can be replaced with a predefined or independently defined control algorithm. The tools necessary to create and test such control algorithms in the therapy dosage module in a simulated environment before implementing it in a live therapy system are also disclosed.
摘要翻译：公开了具有开放结构的治疗递送系统及其提供方法。本发明提供了具有可以用预定义或独立定义的控制算法替代的控制算法的治疗剂量模块。还公开了在实时治疗系统中在模拟环境中创建和测试治疗剂量模块中的这种控制算法所必需的工具。

4. 发明申请

WO2009005958A2 USER INTERFACE FEATURES FOR AN ELECTRONIC DEVICE 审中-公开
标题翻译：用于电子设备的用户界面特征
公开(公告)号：WO2009005958A2
公开(公告)日：2009-01-08
申请号：PCT/US2008/066299
申请日：2008-06-09
申请人： ROCHE DIAGNOSTICS GMBH , F. HOFFMANN-LA ROCHE AG , HOLLIDAY, Rebecca , WERNER, Karl , BUSH, Jason , DAVIS, Stacia , STEINER, Bettina , LONG, Michael, Lee , GALLEY, Paul , MEIERTOBERENS, Ulf
发明人： HOLLIDAY, Rebecca , WERNER, Karl , BUSH, Jason , DAVIS, Stacia , STEINER, Bettina , LONG, Michael, Lee , GALLEY, Paul , MEIERTOBERENS, Ulf
IPC分类号： G06F3/038 , G06F19/00 , G06F1/16 , G06Q10/00
CPC分类号： A61B5/14532 , A61B5/7475 , A61M5/14244 , A61M5/172 , A61M2205/3569 , A61M2205/3592 , A61M2205/502 , A61M2209/01 , G06F1/1626 , G06F1/169 , G06F1/1698 , G06F19/00 , G06F19/3468
摘要： A method is provided for controlling a display device of an electronic device. A data field may be displayed on the display device. An editing process may be executed that provides for editing of the data field displayed on the display device. The data field on the display device may be magnified relative to other portions of the display device when selected for editing according to the editing process.
摘要翻译：提供了一种用于控制电子设备的显示设备的方法。数据字段可以显示在显示设备上。可以执行编辑过程，其提供对显示设备上显示的数据字段的编辑。根据编辑过程选择用于编辑时，显示设备上的数据字段可相对于显示设备的其他部分被放大。

5. 发明申请

WO2007076940A1 PORTABLE ANALYTICAL DEVICE 审中-公开
标题翻译：便携式分析装置
公开(公告)号：WO2007076940A1
公开(公告)日：2007-07-12
申请号：PCT/EP2006/012346
申请日：2006-12-20
申请人： ROCHE DIAGNOSTICS GMBH , F. HOFFMANN-LA ROCHE AG , WERNER, Karl , AFSHAR, Nader , YOUNG, Morris, J. , GALLEY, Paul , GREENBURG, Alan
发明人： WERNER, Karl , AFSHAR, Nader , YOUNG, Morris, J. , GALLEY, Paul , GREENBURG, Alan
IPC分类号： A61B5/00 , A61M5/142 , G06F19/00 , G01N33/487
CPC分类号： A61B5/14532 , A61B5/0002 , A61B5/1455 , A61B5/1468 , A61B2562/0295 , G01N33/48785
摘要： The invention proposes a portable, patient-operable analytical device (1) for analysis of a medically significant component of a body fluid for self- monitoring by a patient, in particular a blood glucose measuring device (2), comprising a device housing (3), a measuring facility arranged inside the device housing (3) for carrying out the analysis on a test element (7) that is inserted through a housing opening (8) into the analytical device (1) and the measuring facility, and a processor with software for processing of the measuring values determined by the measuring facility and for processing the measuring values to yield analytical measuring data taking into account calibration values, that is characterized in that it comprises a standardized, wire-based computer interface (4) by means of which the analytical device (1) can be operated by a computer, the analytical measuring data can be transmitted from the analytical device (1) to the computer, and the analytical device (1) is supplied with electrical power by the computer.
摘要翻译：本发明提出了一种用于分析用于由患者，特别是血糖测量装置（2）自我监测的体液的医学上重要的组分的便携式，患者可操作的分析装置（1），其包括装置壳体（3）），设置在所述装置壳体（3）内部的测量装置，用于对通过壳体开口（8）插入到所述分析装置（1）和所述测量装置中的测试元件（7）进行分析，以及处理器用于处理由测量设备确定的测量值的软件，并且用于处理测量值以产生考虑到校准值的分析测量数据，其特征在于，其包括通过装置的标准化的基于有线的计算机接口（4）其中分析装置（1）可以由计算机操作，分析测量数据可以从分析装置（1）发送到计算机，分析装置（1）为sup 由电脑与电力接合。

6. 发明申请

WO2009005960A2 METHOD AND APPARATUS FOR DETERMINING AND DELIVERING A DRUG BOLUS 审中-公开
标题翻译：确定和传递药物碎片的方法和设备
公开(公告)号：WO2009005960A2
公开(公告)日：2009-01-08
申请号：PCT/US2008/066331
申请日：2008-06-09
申请人： ROCHE DIAGNOSTICS GMBH , F. HOFFMANN-LA ROCHE AG , GALLEY, Paul , ZIVITZ, Maury , WEINERT, Stefan , HELLWIG, Robert
发明人： GALLEY, Paul , ZIVITZ, Maury , WEINERT, Stefan , HELLWIG, Robert
IPC分类号： A61M5/00 , A61B5/00
CPC分类号： A61B5/14532 , A61B5/7475 , A61M5/14244 , A61M5/172 , A61M2205/3569 , A61M2205/3592 , A61M2205/502 , A61M2209/01 , G06F1/1626 , G06F1/169 , G06F1/1698 , G06F19/00 , G06F19/3468
摘要： An electronic device may be configured to prompt a user via an on-board display to measure user glucose via an on-board glucose meter, to compute a first drug bolus value based on the measured user glucose, to display the first drug bolus value on the display and prompt the user via the display to enter carbohydrate information into the device, to compute a second drug bolus value based on the entered carbohydrate information, to display the second drug bolus value on the display and prompt the user via the display to enter user health information into the device, to compute a third drug bolus value based on the entered health information and a total drug bolus value as a sum of the first, second and third drug bolus values, and to display the third and total drug bolus values on the display.
摘要翻译：电子设备可以被配置成经由车载显示器提示用户经由车载葡萄糖计测量用户葡萄糖，以基于测量的用户葡萄糖计算第一药物推注值，以在显示器上显示第一药物团注值，并通过显示器提示用户将碳水化合物信息输入到装置中，基于输入的碳水化合物信息计算第二药物团注值，在显示器上显示第二药物团注值，以及通过显示器提示用户将用户健康信息输入到装置中，基于输入的健康信息和作为第一药物团块值，第二药物团块值和第三药物团块值之和的总药物推注值来计算第三药物团块值，并且在显示屏上显示第三个和总药物浓度值。

7. 发明申请

WO2009005952A3 COMBINATION COMMUNICATION DEVICE AND MEDICAL DEVICE FOR COMMUNICATING WIRELESSLY WITH A REMOTE MEDICAL DEVICE 审中-公开
公开(公告)号：WO2009005952A3
公开(公告)日：2009-01-08
申请号：PCT/US2008/066262
申请日：2008-06-09
申请人： ROCHE DIAGNOSTICS GMBH , F. HOFFMANN-LA ROCHE AG , MEIERTOBERENS, Ulf , CELENTANO, Michael , GALLEY, Paul , SABOL, Peter , STRICKLAND, Raymond, A. , OBERLI, Markus , EHSAM, Matthias , IMHOFF, Erich
发明人： MEIERTOBERENS, Ulf , CELENTANO, Michael , GALLEY, Paul , SABOL, Peter , STRICKLAND, Raymond, A. , OBERLI, Markus , EHSAM, Matthias , IMHOFF, Erich
IPC分类号： A61B5/00 , A61M5/00
摘要： An electronic device may selectively disable a bolus advice process according to which the electronic device recommends delivery of a bolus amount of a drug to a body of a user based on a plurality of factors including glucose concentration of the user. The electronic device may include a glucose measuring facility configured to measure glucose concentration of a body fluid sample, and a processor including a memory having instructions stored therein that comprise the bolus advice process. The memory may further have instructions stored therein that are executable by the processor to request a glucose concentration measurement by the glucose measurement facility prior to executing, or as part of, the bolus advice process, and to disable execution of the bolus advice process if a glucose concentration value resulting from the requested glucose concentration measurement is less than a threshold value.

8. 发明申请

WO2007065285A3 SYSTEM AND METHOD FOR DETERMINING DRUG ADMINISTRATION INFORMATION 审中-公开
公开(公告)号：WO2007065285A3
公开(公告)日：2007-06-14
申请号：PCT/CH2006/000682
申请日：2006-12-04
申请人： F. HOFFMANN-LA ROCHE AG , ROCHE DIAGNOSTICS GMBH
发明人： WEINERT, Stefan , GALLEY, Paul , THUKRAL, Ajay , CHITTAJALLU, Siva , BUCK, Harvey , WAGNER, Robin , MARCO, Kym , LONG, James, R. , BOUSAMRA, Steven
IPC分类号： G06F19/00 , G06F9/44
摘要： A system for determining drug administration information may comprise an input device providing for user input of feed forward information having a first parameter component and a second parameter component, a data storage device and a processor. The data storage de-vice may have stored therein a map correlating values of the first and second parameters to drug administration information. The processor may be responsive to user input of the feed forward information to determine corresponding drug administration information according to the map.

9. 发明申请

WO2009033671A1 MASK ALGORITHMS FOR HEALTH MANAGEMENT SYSTEMS 审中-公开
标题翻译：卫生管理系统的掩码算法
公开(公告)号：WO2009033671A1
公开(公告)日：2009-03-19
申请号：PCT/EP2008/007459
申请日：2008-09-11
申请人： ROCHE DIAGNOSTICS GMBH , F. HOFFMANN-LA ROCHE AG
发明人： ZIVITZ, Maury , GALLEY, Paul , JOVANOVIC, Lois
IPC分类号： G06F19/00
CPC分类号： G06F19/3456 , A61B5/14532 , G06F19/00 , G16H15/00 , G16H40/63 , Y10S706/924
摘要： A device and method of providing information to a healthcare provider regarding the dosing of insulin is provided.
摘要翻译：提供了向医疗保健提供者提供关于胰岛素给药的信息的装置和方法。

10. 发明申请

WO2006131288A1 A SYSTEM AND METHOD PROVIDING FOR USER INTERVENTION IN A DIABETES CONTROL ARRANGEMENT 审中-公开
标题翻译：一种用于糖尿病患者控制布置的用户干预的系统和方法
公开(公告)号：WO2006131288A1
公开(公告)日：2006-12-14
申请号：PCT/EP2006/005344
申请日：2006-06-03
申请人： ROCHE DIAGNOSTICS GMBH , F.HOFFMANN-LA ROCHE AG
发明人： BOUSAMRA, Steven , CHITTAJALLU, Siva , GALLEY, Paul , THUKRAL, Ajay , WAGNER, Robin , WEINERT, Stefan
IPC分类号： G06F19/00 , A61B19/00 , A61M5/142
CPC分类号： A61M5/172 , A61M5/1723 , A61M2005/14208 , A61M2005/14296 , A61M2205/3569 , A61M2230/201 , G06F19/00 , G06F19/3468 , G16H50/50
摘要： A system providing for user intervention in a medical control arrangement may comprise a first user intervention mechanism responsive to user selection thereof to produce a first user intervention signal, a second user intervention mechanism responsive to user selection thereof to produce a second user intervention signal, and a processor executing a drug delivery algorithm forming part of the medical control arrangement. The processor may be responsive to the first user intervention signal to include an intervention therapy value in the execution of the drug delivery algorithm, and responsive to the second user intervention signal to exclude the intervention therapy value from the execution of the drug delivery algorithm. The medical control arrangement may be a diabetes control arrangement, the drug delivery algorithm may be an insulin delivery algorithm, and the intervention therapy value may be, for example, an intervention insulin quantity or an intervention carbohydrate quantity.
摘要翻译：提供用户干预医疗控制装置的系统可以包括响应于用户选择其以产生第一用户干预信号的第一用户干预机制，响应于用户选择以产生第二用户干预信号的第二用户干预机制，以及执行形成医疗控制装置的一部分的药物递送算法的处理器。所述处理器可以响应于所述第一用户干预信号，以在所述药物递送算法的执行中包括干预治疗值，并且响应于所述第二用户干预信号排除所述介入治疗值与所述药物递送算法的执行。医疗控制装置可以是糖尿病控制装置，药物递送算法可以是胰岛素递送算法，并且干预治疗值可以是例如干预胰岛素量或干预碳水化合物量。

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