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1. 发明申请

WO2010075115A3 BODY-ASSOCIATED RECEIVER AND METHOD 审中-公开
标题翻译：身体关联接收机和方法
公开(公告)号：WO2010075115A3
公开(公告)日：2010-09-23
申请号：PCT/US2009068128
申请日：2009-12-15
申请人： PROTEUS BIOMEDICAL INC , ROBERTSON TIMOTHY , OMIDVAR FATANEH , BEHZADI YASHAR , ARNE LAWRENCE , ROWBERRY KENNETH , HUTCHISON JAMES , LEICHNER ROBERT , SAVAGE GEORGE , THOMPSON ANDREW , ZDEBLICK MARK , KREIDLER MARC , HAFEZI HOOMAN , DUCK ROBERT
发明人： ROBERTSON TIMOTHY , OMIDVAR FATANEH , BEHZADI YASHAR , ARNE LAWRENCE , ROWBERRY KENNETH , HUTCHISON JAMES , LEICHNER ROBERT , SAVAGE GEORGE , THOMPSON ANDREW , ZDEBLICK MARK , KREIDLER MARC , HAFEZI HOOMAN , DUCK ROBERT
IPC分类号： A61B5/05 , A61B5/048 , H04B13/00
CPC分类号： A61M5/1723 , A61B5/0006 , A61B5/0028 , A61B5/02055 , A61B5/0404 , A61B5/04085 , A61B5/0428 , A61B5/053 , A61B5/11 , A61B5/1112 , A61B5/145 , A61B5/14532 , A61B5/4094 , A61B2560/0209 , A61B2560/0412 , A61B2560/0468 , A61B2562/0219 , A61M5/1452 , A61M5/172 , G06F19/34 , G06F19/3418 , H04B13/005
摘要： Receivers, which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power supplies to a high power processing block; a serial peripheral interface bus connecting master and slave blocks; and a multi-purpose connector. Receivers of the invention may be configured to receive a conductively transmitted signal. Also provided are systems that include the receivers, as well as methods of using the same. Additionally systems and methods are disclosed for using a receiver for coordinating with dosage delivery systems.
摘要翻译：提供接收器，可能是外置的或可植入的。本发明的接收器的方面包括以下中的一个或多个的存在：高功率低功率模块; 中介模块; 电源模块，被配置为激活和去激活到高功率处理块的一个或多个电源; 一个连接主和从块的串行外设接口总线; 和一个多用途连接器。本发明的接收器可以被配置为接收传导传输的信号。还提供了包括接收器的系统以及使用它们的方法。另外公开了使用接收器与剂量递送系统协调的系统和方法。

2. 发明申请

WO2010080843A3 INGESTION-RELATED BIOFEEDBACK AND PERSONALIZED MEDICAL THERAPY METHOD AND SYSTEM 审中-公开
标题翻译：与摄入有关的生物反馈和个人化医疗治疗方法和系统
公开(公告)号：WO2010080843A3
公开(公告)日：2010-10-21
申请号：PCT/US2010020269
申请日：2010-01-06
申请人： PROTEUS BIOMEDICAL INC , JENSEN MARC , LEICHNER ROBERT , BEAULIEU PATRICK , AU-YEUNG KIT YEE , ARNE LAWRENCE , ZDEBLICK MARK , THOMPSON ANDREW , SAVAGE GEORGE , ROBERTSON TIMOTHY , BEHZADI YASHAR
发明人： JENSEN MARC , LEICHNER ROBERT , BEAULIEU PATRICK , AU-YEUNG KIT YEE , ARNE LAWRENCE , ZDEBLICK MARK , THOMPSON ANDREW , SAVAGE GEORGE , ROBERTSON TIMOTHY , BEHZADI YASHAR
IPC分类号： A61B1/00 , A61B5/02 , A61B5/0482 , H04B13/00
CPC分类号： A61B5/073 , A61B5/0002 , A61B5/021 , A61B5/024 , A61B5/1112 , A61B5/486 , A61B5/6833 , G06F19/3456 , G06F19/3481 , G16H10/60 , H04B13/005
摘要： Methods, devices and systems for acquiring information useful to support a patient in implementing and adhering to a medically prescribed therapy plan are provided. The therapy may incorporate biofeedback methods and/or personalized therapy aspects. A method includes steps of receiving, by a receiving device, biometric information associated with an ingestible event marker; analyzing, by a computing device having a microprocessor configured to perform a biometric information analysis, the biometric information; and determining a therapeutic recommendation at least partly on the basis of the analysis and/or integrating biofeedback techniques into patient therapy or activity. A system includes a biometric information module to receive biometric information associated with an ingestible event marker; an analysis module to analyze the biometric information; and a determination module to optionally determine and communicate a therapeutic recommendation at least partly on the basis of the analysis.
摘要翻译：提供了用于获取有用的信息的方法，设备和系统，以支持患者实施和遵守医学上规定的治疗计划。该疗法可以包含生物反馈方法和/或个性化治疗方面。一种方法包括以下步骤：由接收设备接收与可摄入事件标记相关联的生物测量信息; 通过具有被配置为执行生物计量信息分析的微处理器的计算设备分析所述生物计量信息; 以及至少部分基于分析和/或将生物反馈技术整合到患者治疗或活动中来确定治疗推荐。一种系统包括：生物统计信息模块，用于接收与可摄入事件标记相关联的生物统计信息; 分析模块，用于分析生物信息; 以及确定模块，用于至少部分地基于所述分析来可选地确定和传达治疗建议。

3. 发明申请

WO2010005877A3 INGESTIBLE EVENT MARKER DATA FRAMEWORK 审中-公开
标题翻译：不可思议的事件标记数据框架
公开(公告)号：WO2010005877A3
公开(公告)日：2010-03-11
申请号：PCT/US2009049618
申请日：2009-07-02
申请人： PROTEUS BIOMEDICAL INC , O'REILLY DAVID , KARPLUS ERIKA , THOMPSON ANDREW , SAVAGE GEORGE , ZDEBLICK MARK , ROBERTSON TIMOTHY , ARNE LAWRENCE , BEHZADI YASHAR , MOON GREGORY , BEAULIEU PATRICK
发明人： O'REILLY DAVID , KARPLUS ERIKA , THOMPSON ANDREW , SAVAGE GEORGE , ZDEBLICK MARK , ROBERTSON TIMOTHY , ARNE LAWRENCE , BEHZADI YASHAR , MOON GREGORY , BEAULIEU PATRICK
IPC分类号： A61B5/06 , G05F1/00 , H04B13/00
CPC分类号： A61B5/07 , A61B5/0022 , A61B5/021 , G06F19/3418 , G06F19/3456
摘要： The ingestible event marker data framework provides a uniform, comprehensive framework to enable various functions and utilities related to ingestible event marker data (IEM data). The functions and utilities include data and / or information having an aspect of data derived from, collected by, aggregated by, or otherwise associated with, an ingestion event.
摘要翻译：可摄入事件标记数据框架提供统一的全面框架，以实现与可摄取事件标记数据（IEM数据）相关的各种功能和实用程序。功能和实用程序包括具有从摄取事件导出，收集，聚合或以其他方式与之相关的数据的方面的数据和/或信息。

4. 发明申请

WO2010045385A3 METHOD AND SYSTEM FOR INCORPORATING PHYSIOLOGIC DATA IN A GAMING ENVIRONMENT 审中-公开
标题翻译：在游戏环境中包含生理数据的方法和系统
公开(公告)号：WO2010045385A3
公开(公告)日：2010-07-22
申请号：PCT/US2009060713
申请日：2009-10-14
申请人： PROTEUS BIOMEDICAL INC , THOMPSON ANDREW , SAVAGE GEORGE , KARPLUS ERIKA , ARNE LAWRENCE , ROBERTSON TIMOTHY , O'REILLY DAVID
发明人： THOMPSON ANDREW , SAVAGE GEORGE , KARPLUS ERIKA , ARNE LAWRENCE , ROBERTSON TIMOTHY , O'REILLY DAVID
IPC分类号： G06Q50/00
CPC分类号： A63F13/23 , A61B5/02055 , A61B5/02405 , A61B5/073 , A61B5/0816 , A61B5/4833 , A63F13/02 , A63F13/212 , A63F2300/1012 , A63F2300/6045 , G06Q50/00 , G07F17/32 , G07F17/3206 , G07F17/3237
摘要： The present invention provides a receiving device and method for use with gaming pursuits, including, in one aspect, a personal signal receiver to communicate physiologic data, a hub to receive the physiologic data, and a gaming module to receive, directly or indirectly, the physiologic data from the hub.
摘要翻译：本发明提供了一种用于与游戏活动一起使用的接收设备和方法，在一个方面，其包括传送生理数据的个人信号接收器，接收生理数据的集线器以及直接或间接接收来自枢纽的生理数据。

5. 发明申请

WO2007005641A3 DEPLOYABLE EPICARDIAL ELECTRODE AND SENSOR ARRAY 审中-公开
标题翻译：可展开的心电电极和传感器阵列
公开(公告)号：WO2007005641A3
公开(公告)日：2007-10-04
申请号：PCT/US2006025648
申请日：2006-06-30
申请人： PROTEUS BIOMEDICAL INC , JENSEN MARC , COLLIOU OLIVIER , COSTELLO BENEDICT , ZDEBLICK MARK , THOMPSON TODD , SAVAGE GEORGE , THOMPSON ANDREW
发明人： JENSEN MARC , COLLIOU OLIVIER , COSTELLO BENEDICT , ZDEBLICK MARK , THOMPSON TODD , SAVAGE GEORGE , THOMPSON ANDREW
IPC分类号： A61N1/05
CPC分类号： A61N1/0587
摘要： Minimally invasive deployable epicardial array devices are provided. The devices include deployable platform comprising two or more effectors, such as sensors and actuators, where the devices are configured to be deployed at an epicardial location via a minimally invasive, e.g., sub-xiphoid approach. In embodiments of the present invention, at least one area of the electrode patch is an electrical control area that comprises a series of effectors, e.g., sensors and/or electrodes. Other embodiments provide localized physical constraint and dynamic mechanical stimulation of the heart to effectuate physical and biological responses. Still other embodiments provide both of these functions. Also provided are methods of using the devices, as well as systems and kits that include the devices.
摘要翻译：提供了微创可展开心外膜阵列装置。这些装置包括可展开的平台，其包括两个或更多个效应器，例如传感器和致动器，其中所述装置被配置为经由微创，例如，剑突下方法被部署在心外膜位置。在本发明的实施例中，电极贴片的至少一个区域是包括一系列效应器（例如传感器和/或电极）的电控制区域。其他实施例提供心脏的局部物理约束和动态机械刺激以实现物理和生物反应。还有其他实施例提供这两种功能。还提供了使用这些设备的方法，以及包括这些设备的系统和套件。

6. 发明申请

WO2007130491A2 PATIENT CUSTOMIZED THERAPEUTIC REGIMENS 审中-公开
标题翻译：患者自定义治疗方案
公开(公告)号：WO2007130491A2
公开(公告)日：2007-11-15
申请号：PCT/US2007010688
申请日：2007-05-02
申请人： PROTEUS BIOMEDICAL INC , ZDEBLICK MARK , THOMPSON ANDREW , SAVAGE GEORGE
发明人： ZDEBLICK MARK , THOMPSON ANDREW , SAVAGE GEORGE
IPC分类号： G06Q10/00
CPC分类号： G06F19/3456 , A61B5/0002 , A61B5/0028 , A61B5/073 , A61B5/4833 , A61B5/4848 , G06F19/34 , G06F19/3418 , G06F19/3475 , G06Q10/00 , G06Q50/22 , G16H50/20 , H01M8/02 , H01M2220/10 , H04B13/005 , Y10S128/903 , Y10S128/92
摘要： Methods, systems and compositions that allow for treating a patient according to a patient customized therapeutic regimen are provided. Embodiments of the invention include obtaining dosage administration information from a patient and using the same to tailor a therapeutic regimen for the patient. Embodiments of the invention further include preparing and forwarding to the patient physical pharmaceutical dosages based on the customized therapeutic regimen.
摘要翻译：提供了允许根据患者定制的治疗方案治疗患者的方法，系统和组合物。本发明的实施方案包括从患者获得剂量给药信息并使用它来定制患者的治疗方案。本发明的实施方案还包括基于定制的治疗方案制备并转发患者物理药物剂量。

7. 发明申请

WO2006116718A3 PHARMA-INFORMATICS SYSTEM 审中-公开
标题翻译：药物信息系统
公开(公告)号：WO2006116718A3
公开(公告)日：2008-01-17
申请号：PCT/US2006016370
申请日：2006-04-28
申请人： PROTEUS BIOMEDICAL INC , ZDEBLICK MARK , THOMPSON ANDREW , PIKELNY ALEKSANDR , ROBERTSON TIMOTHY
发明人： ZDEBLICK MARK , THOMPSON ANDREW , PIKELNY ALEKSANDR , ROBERTSON TIMOTHY
IPC分类号： A61B5/07 , A61K9/48
CPC分类号： A61B5/6861 , A61B5/0028 , A61B5/0031 , A61B5/07 , A61B5/073 , A61B5/1473 , A61B5/4833 , A61B5/4839 , A61B5/681 , A61B5/7282 , A61B2560/0214 , A61B2560/0462 , A61B2562/08 , A61B2562/162 , A61J3/007 , G06K7/10168 , H01Q1/273 , Y10T29/49117
摘要： Compositions, systems and methods that allow for the detection of the actual physical delivery of a pharmaceutical agent to a body are provided. Embodiments of the compositions include an identifier and an active agent. The invention finds use in a variety of different applications, including but not limited to, monitoring of therapeutic regimen compliance, tracking the history of pharmaceutical agents, etc.
摘要翻译：提供了允许检测药物到身体的实际物理输送的组合物，系统和方法。组合物的实施方案包括标识符和活性剂。本发明可用于各种不同的应用，包括但不限于监测治疗方案依从性，跟踪药剂的历史等。

8. 发明申请

WO2004086050A2 MASS LABELS 审中-公开
标题翻译：质量标签
公开(公告)号：WO2004086050A2
公开(公告)日：2004-10-07
申请号：PCT/GB2004001167
申请日：2004-03-18
申请人： XZILLION GMBH & CO KG , PROTEOME SCIENCES PLC , HAMON CHRISTIAN , KUHN KARSTEN , THOMPSON ANDREW , REUSCHLING DIETER , SCHAEFER JUERGEN
发明人： HAMON CHRISTIAN , KUHN KARSTEN , THOMPSON ANDREW , REUSCHLING DIETER , SCHAEFER JUERGEN
IPC分类号： C07D207/46 , C07D211/14 , C07D295/15 , C07D401/12 , C07K1/13 , G01N33/68 , G01N33/58 , C07K1/18
CPC分类号： G01N33/68 , C07B2200/05 , C07C229/12 , C07D207/46 , C07D211/14 , C07D295/15 , C07D401/12 , C07K1/13 , C40B40/04 , C40B70/00 , G01N33/6848 , G01N2458/15 , Y10T436/24
摘要： Provided is a method for characterising a molecule by mass spectrometry, which molecule comprises one or more free amino groups, which method comprises: (a) reacting one or more free amino groups in the molecule with a mass tag reagent comprising a reactive functionality capable of reacting with an amino group, and a tertiary amino group linked to the reactive functionality; and (b) characterising the molecule by mass spectrometry.
摘要翻译：本发明提供了一种通过质谱鉴定分子的方法，该分子包含一个或多个游离氨基，该方法包括：（a）使分子中的一个或多个游离氨基与包含能够与氨基反应，和与反应性官能团连接的叔氨基; 和（b）通过质谱鉴定分子。

9. 发明申请

WO2010048327A1 SYNTHETIC NAVEL ORANGEWORM PHEROMONE COMPOSITION AND METHODS RELATING TO PRODUCTION OF SAME 审中-公开
标题翻译：合成水合物与其生产相关的PHERMONE组合物及方法
公开(公告)号：WO2010048327A1
公开(公告)日：2010-04-29
申请号：PCT/US2009061535
申请日：2009-10-21
申请人： SUTERRA LLC , THOMPSON ANDREW , ZHANG XIONGZHI , ROBARGE LONNIE
发明人： THOMPSON ANDREW , ZHANG XIONGZHI , ROBARGE LONNIE
IPC分类号： C07C47/21 , C07C45/42
CPC分类号： C07C45/42 , C07C29/44 , C07C29/58 , C07C41/48 , C07C41/56 , C07C45/29 , C07C45/515 , C07C47/14 , C07C47/222 , C07C43/313 , C07C43/303
摘要： One or more embodiments of the invention are directed to the synthetic methods for making lepidopteran pheromones including navel orangeworm pheromones. The synthetic methods involve novel, efficient, and environmentally benign steps and procedures.
摘要翻译：本发明的一个或多个实施方案涉及用于制备包括脐橙交感神经元的鳞翅目信息素的合成方法。合成方法涉及新颖，有效和环境友好的步骤和程序。

10. 发明申请

WO2008032301A3 A GOLF CLUB CLEANING DEVICE AND A COUPLING MEMBER 审中-公开
标题翻译：高尔夫球杆清洁装置和连接件
公开(公告)号：WO2008032301A3
公开(公告)日：2008-05-08
申请号：PCT/IE2007000084
申请日：2007-09-17
申请人： THOMPSON ANDREW , DOWLING JAMES MARTIN , MOORE BRENDAN MICHAEL , MURPHY CHRISTOPHER , BRYCE LYNDSEY , SKELTON EUGENE
发明人： THOMPSON ANDREW , DOWLING JAMES MARTIN , MOORE BRENDAN MICHAEL , MURPHY CHRISTOPHER , BRYCE LYNDSEY , SKELTON EUGENE
IPC分类号： A63B57/00 , A45F5/02
CPC分类号： A46B5/06 , A45F5/02 , A46B2200/3073 , A63B55/408 , A63B57/60 , A63B2057/605 , A63B2209/08 , A63B2209/10
摘要： A golf club cleaning device (1) comprises a channel shaped carrier housing (2) of inverted U-shaped construction having spaced apart front and rear side panels (4,5) joined by a connecting panel (8) and defining a club head accommodating passageway (12). A brush element located in the passageway (12) comprises resilient bristles (16) which extend into the passageway (12) from the front and rear side panels (4,5) and the connecting panel (8) for engaging the front face and rear or cavity and the sole of a golf club as the golf club is being urged through the passageway (12) for removing dirt ingrained in grooves of the golf club head. A towel (25) is releasably secured at its opposite free ends (26) to distal ends (30) of the front and rear panels (4,5) and depends downwardly from the carrier housing (2) to form a U-shape for cleaning and drying the club head, the shaft and the hand grip of a golf club. A coupling member (35) is releasably secured to the carrier housing (2) and forms a hook (42) for engaging a golf club bag adjacent a top rim thereof for releasably securing the cleaning device (1 ) to the golf club bag.
摘要翻译：高尔夫球杆清洁装置（1）包括倒U形结构的槽形载体外壳（2），其具有由连接面板（8）连接的间隔开的前后侧板（4,5）通道（12）。位于通道（12）中的刷元件包括弹性刷毛（16），所述刷毛从前后侧板（4,5）和连接板（8）延伸到通道（12）中，用于接合前侧和后侧或者当高尔夫球杆被推动穿过通道（12）以去除在高尔夫球杆头的凹槽中沉积的污垢时，高尔夫球杆的空腔和空腔以及高尔夫球杆的底部。毛巾（25）在其相对的自由端（26）处可释放地固定到前板和后板（4,5）的远端（30）并且从载体外壳（2）向下悬垂以形成用于清洁和干燥高尔夫球杆的杆头，杆身和手柄。联接构件（35）可释放地固定到承载器壳体（2）并且形成用于接合邻近其顶部边缘的高尔夫球杆袋的钩（42），用于将清洁装置（1）可释放地固定到高尔夫球杆袋。

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