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1. 发明申请

WO2008139374A1 METHOD FOR PLANNING 2D X-RAY EXAMINATIONS 审中-公开
标题翻译：用于规划2D X射线检查的方法
公开(公告)号：WO2008139374A1
公开(公告)日：2008-11-20
申请号：PCT/IB2008/051785
申请日：2008-05-07
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , PEKAR, Vladimir , WIEMKER, Rafael , BYSTROV, Daniel , OPFER, Roland , VON BERG, Jens , KUHN, Michael, H.
发明人： PEKAR, Vladimir , WIEMKER, Rafael , BYSTROV, Daniel , OPFER, Roland , VON BERG, Jens , KUHN, Michael, H.
IPC分类号： A61B6/04 , A61B6/08
CPC分类号： A61B6/04 , A61B6/08 , A61B6/488
摘要： It is described a method for automatically determine the optimal patient pose and system positioning for X-ray radiographic examinations. The method is based on a first acquiring of one or more ultra- low-dose scout images, which are automatically analyzed by an image processing system. The aim is to compute the parameters for optimal positioning of the patient and the X-ray system such that the diagnostic image corresponds optimally either to an earlier examination in a follow-up study, or to predefined examination-specific standard pose.
摘要翻译：描述了一种用于自动确定X射线照相检查的最佳患者姿势和系统定位的方法。该方法基于第一次获取由图像处理系统自动分析的一个或多个超低剂量侦察图像。目的是计算用于患者和X射线系统的最佳定位的参数，使得诊断图像最佳地对应于随访研究中的较早检查，或预定义的检查特定标准姿态。

2. 发明申请

WO2006085268A1 IMAGE PROCESSING DEVICE AND METHOD 审中-公开
标题翻译：图像处理装置和方法
公开(公告)号：WO2006085268A1
公开(公告)日：2006-08-17
申请号：PCT/IB2006/050403
申请日：2006-02-08
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , VON BERG, Jens , LORENZ, Cristian
发明人： VON BERG, Jens , LORENZ, Cristian
IPC分类号： G06T5/00
CPC分类号： G06T7/149 , G06T7/12 , G06T2207/10072 , G06T2207/30048
摘要： The present invention relates to an image processing device and a corresponding image processing method for processing a multi- dimensional data set of image data, in particular of three-dimensional medical volume image data, including a segmentation unit (6, 16, 26) for a segmentation of an image object in said data set. Further, the present invention relates to a computer program for implementing said image processing method on a computer. In order to allow for a segmentation which is robust in terms of vulnerability to image artifacts and accurate in terms of reflecting anatomical details, wherein the results of the segmentation are achieved within reasonable short processing time an image processing device is proposed which comprises - model-based segmentation means (61, 161, 261) for performing a model-based segmentation (32) of said data set for obtaining a multi- dimensional model representing a first approximation of said image object; data-driven segmentation means (62, 162, 262) for performing a data- driven segmentation (33) of said multi- dimensional data set for obtaining a multi- dimensional subset of said multi- dimensional data set representing a second approximation of said image object; optimizing means (63, 163, 263) for adapting said model and/or said subset for optimizing a similarity value between said first and said second approximation; and - selecting means (64, 164, 264) for selecting said adapted model or said adapted subset as a segmentation of said image object.
摘要翻译：本发明涉及一种用于处理图像数据的多维数据集，特别是三维医疗卷图像数据的图像处理装置和相应的图像处理方法，其包括分割单元（6,16,26），用于所述数据集中的图像对象的分割。此外，本发明涉及一种用于在计算机上实现所述图像处理方法的计算机程序。为了允许在对图像伪影的脆弱性和在反映解剖细节方面的准确性方面是鲁棒的分割，其中在合理的短处理时间内实现分割的结果，提出了一种图像处理装置，其包括 - 模型 - （61,161,261），用于执行所述数据集的基于模型的分割（32），以获得表示所述图像对象的第一近似的多维模型; 数据驱动分割装置（62,162,262），用于执行所述多维数据集的数据驱动分段（33），以获得表示所述图像的第二近似的所述多维数据集的多维子集目的; 用于调整所述模型和/或所述子集以优化所述第一和所述第二近似之间的相似度值的优化装置（63,163,263）以及 - 选择装置（64,164,264），用于选择所述适配模型或所述适配子集作为所述图像对象的分割。

3. 发明申请

WO2006117719A3 MULTI-SURFACE MODELLING 审中-公开
公开(公告)号：WO2006117719A3
公开(公告)日：2006-11-09
申请号：PCT/IB2006/051284
申请日：2006-04-25
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , VON BERG, Jens , LORENZ, Cristian
发明人： VON BERG, Jens , LORENZ, Cristian
IPC分类号： G06T17/20
摘要： Modelling of organ surfaces is a well-established method that may serve in computer-supported teaching, but also in image-based medical diagnosis and in clinical interventions. According to an exemplary embodiment of the present invention, a method of constructing a multi-surface model from a multi-dimensional dataset of an object of interest is provided, which combines single basic two-dimensional manifold surface meshes, resulting in a multi-surface model. According to an aspect of the present invention, this resulting model may be a non-two-dimensional manifold mesh.

4. 发明申请

WO2005083629A1 DEVICE AND PROCESS FOR MULTIMODAL REGISTRATION OF IMAGES 审中-公开
标题翻译：多模式注册图像的设备和过程
公开(公告)号：WO2005083629A1
公开(公告)日：2005-09-09
申请号：PCT/IB2005/050468
申请日：2005-02-04
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , MEETZ, Kirsten , SCHULZ, Heinrich , VON BERG, Jens , SABCZYNSKI, Joerg
发明人： MEETZ, Kirsten , SCHULZ, Heinrich , VON BERG, Jens , SABCZYNSKI, Joerg
IPC分类号： G06T7/00
CPC分类号： G06T3/4061 , G06T7/30 , G06T2207/10072 , G06T2207/10116 , G06T2207/10132 , G06T2207/30016 , Y10S128/922
摘要： The invention relates to a device and a process, with which images of different imaging methods can be registered, for example preoperatively obtained 3D X-ray images (A) and intra operatively obtained ultrasound images (B). First transformed images (A',B') are then generated in a data processing device (10), which are aligned to each other with regard to the peculiarities of each imaging method. Particularly from the three dimensional CT-image (A), can be generated a two dimensional image (A') which adheres to the characteristic means of representation of an ultrasound system, while shaded areas behind bones and/or gas-filled volumes can be blended out. With a feature-based registration of the transformed images (A', B') errors are avoided, which are traced back to artifacts and peculiarities of the respective imaging methods.
摘要翻译：本发明涉及可以登记不同成像方法的图像的装置和方法，例如，术前获得的3D X射线图像（A）和经操作获得的超声图像（B）。然后，在数据处理装置（10）中生成第一变换图像（A'，B'），这些数据处理装置相对于每个成像方法的特性彼此对准。特别是从三维CT图像（A）可以产生一个二维图像（A'），它粘附在超声系统的表征的特征上，而在骨骼和/或充气体积之后的阴影区可以是混合了通过改变的图像（A'，B'）的基于特征的注册，避免了错误，这些错误被追溯到各个成像方法的伪影和特征。

5. 发明申请

WO2005055147A1 METHOD OF DETERMINING A STRUCTURE OF A MOVING OBJECT 审中-公开
标题翻译：确定移动物体结构的方法
公开(公告)号：WO2005055147A1
公开(公告)日：2005-06-16
申请号：PCT/IB2004/052552
申请日：2004-11-25
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , VON BERG, Jens , LORENZ, Cristian , GIJSBERS, Geert
发明人： VON BERG, Jens , LORENZ, Cristian , GIJSBERS, Geert
IPC分类号： G06T11/00
CPC分类号： G06T7/251 , G06T7/12 , G06T7/149 , G06T2207/10121 , G06T2207/30048 , G06T2207/30101
摘要： In patients with chronic total occlusions (CTO) in coronary arteries, the whole vessel branch beyond the CTO is usually not visible in angiographic images because no contrast agent is transported there. According to an exemplary embodiment of the present invention, a model of a structure of interest of a moving object, i.e. for example, a model of the coronary artery tree of the human heart is applied to a data set or image of the object interest. The model is adapted to features of the image. Then, a location of at least one portion of the structure is estimated by using the adapted model. According to an exemplary embodiment of the present invention, the adapted model is overlaid onto the measured image and displayed to a user, allowing, for example, for a determination of a CTO case, which becomes obvious by a vessel branch indicated as missing.
摘要翻译：在冠状动脉慢性完全闭塞（CTO）患者中，超过CTO的整个血管分支通常在血管造影图像中不可见，因为没有造影剂在那里运输。根据本发明的示例性实施例，将运动物体的兴趣结构的模型，即例如人心脏的冠状动脉树的模型应用于对象感兴趣的数据集或图像。该模型适用于图像的特征。然后，通过使用适配模型来估计结构的至少一部分的位置。根据本发明的示例性实施例，将适配模型覆盖在所测量的图像上并显示给用户，允许例如确定CTO病例，其由指示为丢失的血管分支变得明显。

6. 发明申请

WO2008041165A2 MODEL-BASED CORONARY CENTERLINE LOCALIZATION 审中-公开
标题翻译：基于模型的冠状动脉中心定位
公开(公告)号：WO2008041165A2
公开(公告)日：2008-04-10
申请号：PCT/IB2007/053949
申请日：2007-09-28
申请人： KONINKLIJKE PHILIPS ELECTRONICS N. V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , VON BERG, Jens , HOFMANN, Bernd , LORENZ, Cristian , ECABERT, Olivier , PETERS, Jochen , WEESE, Juergen
发明人： VON BERG, Jens , HOFMANN, Bernd , LORENZ, Cristian , ECABERT, Olivier , PETERS, Jochen , WEESE, Juergen
CPC分类号： G06T7/30 , A61B5/055 , A61B6/504 , A61B6/5229 , A61B8/0891 , A61B8/5238 , G06F19/00 , G06T2207/20044 , G06T2207/30101 , Y10S128/922
摘要： The invention relates to a system (100) for registering a vessel model with an image data set based on a joined model comprising a reference object model and the vessel model, the system comprising: a placement unit (110) for placing the joined model in a space of the image data set, thereby creating a placed joined model comprising a placed reference object model and a placed vessel model; a computation unit (120) for computing a deformation field based on a landmark displacement field comprising displacements of landmarks of the placed reference object model relative to corresponding landmarks in the image data set; a transformation unit (130) for transforming the placed joined model using the deformation field, thereby creating a transformed joined model comprising a transformed reference object model and a transformed vessel model; and a registration unit (140) for registering the transformed vessel model with the image data set based on modifying the transformed vessel model and optimizing an objective function of the modified transformed vessel model, wherein the objective function comprises a location-prior term based on a localization of the modified transformed vessel model relative to the transformed joined model. Hence, the system is arranged to model a vessel taking into account the localization of a vessel model relative to a reference anatomical structure described by a reference model.
摘要翻译：本发明涉及一种用于根据包括参考对象模型和血管模型的联合模型将具有图像数据集的血管模型登记的系统（100），所述系统包括：放置单元（110），用于将所连接的模型放置在图像数据集合的空间，从而创建包括放置的参考对象模型和放置的容器模型的放置的连接模型; 计算单元（120），用于基于地标位移场来计算变形场，所述地标位移场包括相对于所述图像数据组中的对应界标放置的参考对象模型的界标的位移; 变换单元（130），用于使用变形场来变换放置的接合模型，从而创建包括变换的参考对象模型和变换的容器模型的变换的连接模型; 以及注册单元（140），用于基于修改所述经变换的血管模型并优化所述经修改的转化的血管模型的目标函数，将经变换的血管模型与所述图像数据集进行登记，其中所述目标函数包括基于修改的转化血管模型相对于转化的连接模型的定位。因此，该系统被设置成考虑到血管模型相对于由参考模型描述的参考解剖结构的定位来建模血管。

7. 发明申请

WO2006085248A1 IMAGE PROCESSING DEVICE AND METHOD 审中-公开
标题翻译：图像处理装置和方法
公开(公告)号：WO2006085248A1
公开(公告)日：2006-08-17
申请号：PCT/IB2006/050360
申请日：2006-02-03
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , VON BERG, Jens , LORENZ, Cristian
发明人： VON BERG, Jens , LORENZ, Cristian
CPC分类号： G06T7/149 , G06T7/12 , G06T2207/10072 , G06T2207/30048
摘要： The present invention relates to an image processing device and a corresponding image processing method for processing medical image data showing at least two image objects, including a segmentation unit for detection and/or segmentation of image objects in said image data. To allow a more accurate and better segmentation of target objects which are hard to localize and detect, it is proposed that the segmentation unit comprises: a selection unit (61) for selecting a target object for detection and/or segmentation and an intermediary object in said image data, which is easier detectable than said target object and for which position information about the spatial relationship to said target object are known, an intermediary object segmentation unit (62) for segmentation of said intermediary object in said image data, a target object detection unit (63) for detection and/or segmentation of said target object in said image data using said segmented intermediary object and said position information about the spatial relationship of said intermediary object to said target object.
摘要翻译：图像处理装置及图像处理方法技术领域本发明涉及图像处理装置和图像处理方法，该图像处理方法用于处理表示至少两个图像对象的医学图像数据，所述图像对象包括用于所述图像数据中的图像对象的检测和/或分割的分割单元。为了允许对难以定位和检测的目标对象进行更准确和更好的分割，提出了分割单元包括：选择单元（61），用于选择用于检测和/或分割的目标对象以及中间对象所述图像数据比所述目标对象更容易检测，并且关于与所述目标对象的空间关系的位置信息是已知的），用于在所述图像数据中分割所述中间对象的中间对象分割单元（62），目标对象检测单元（63），用于使用所述分割的中间对象在所述图像数据中检测和/或分割所述目标对象，以及关于所述中间对象与所述目标对象的空间关系的位置信息。

8. 发明申请

WO2009063363A2 COMPUTER-AIDED DETECTION (CAD) OF A DISEASE 审中-公开
标题翻译：一种疾病的计算机辅助检测（CAD）
公开(公告)号：WO2009063363A2
公开(公告)日：2009-05-22
申请号：PCT/IB2008/054632
申请日：2008-11-06
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , LORENZ, Cristian , VON BERG, Jens , BUELOW, Thomas , WIEMKER, Rafael
发明人： LORENZ, Cristian , VON BERG, Jens , BUELOW, Thomas , WIEMKER, Rafael
IPC分类号： G06T7/00
CPC分类号： G06T7/0012 , G06T7/11 , G06T2200/24 , G06T2207/10072 , G06T2207/30061
摘要： The present invention relates to a method for performing computer-aided detection (CAD) of a disease, e.g. lung tumours, on a medical image data set (20) from a imaging modality, such as MRI or CT. Initially, there is perform a segmentation of the medical image data set (20) using an anatomical model. Secondly, the segmented data is analyzed for characteristics of the disease resulting in a set of analysis data (25), and finally the set of analysis data (25) is evaluating with respect to the disease. At least one of these steps comprises as an input a position dependent probability (P_r) for the disease. The invention isadvantageous in that more efficient computations can be performed because the degree ofanalysis in a certain region of the part of the patient, e.g. the lung, can be adjusted or tailored to the level of probability of the disease in the that region. It is thereby possible to increase computational speed and thereby diseases like cancer, in particular cancer nodules in the lungs, can be more effectively found from medical image analysis.
摘要翻译：用于执行疾病的计算机辅助检测（CAD）的方法技术领域本发明涉及用于执行疾病的计算机辅助检测（CAD）的方法。（例如MRI或CT）的医学图像数据组（20）上的肺肿瘤。最初，使用解剖模型执行医学图像数据集（20）的分割。其次，对分段数据进行分析，以获得一组分析数据（25），最后分析数据集（25）针对该疾病进行评估。这些步骤中的至少一个包括疾病的位置依赖概率（P_r）作为输入。本发明的有利之处在于可以进行更有效的计算，因为患者部分的某个区域的分析程度，例如，肺，可以调整或适应该地区疾病的概率水平。因此可以提高计算速度，从而可以从医学图像分析中更加有效地发现诸如癌症的疾病，特别是肺部的癌症结节。

9. 发明申请

WO2009101560A2 APPARATUS FOR SEGMENTING AN OBJECT COMPRISING SUB-OBJECTS 审中-公开
标题翻译：用于分配包含子对象的对象的设备
公开(公告)号：WO2009101560A2
公开(公告)日：2009-08-20
申请号：PCT/IB2009/050495
申请日：2009-02-06
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BLAFFERT, Thomas , BARSCHDORF, Hans , VON BERG, Jens , DRIES, Sebastian, P., M. , LORENZ, Cristian , WIEMKER, Rafael , KLINDER, Tobias , FRANZ, Astrid, R. , RENISCH, Steffen
发明人： BLAFFERT, Thomas , BARSCHDORF, Hans , VON BERG, Jens , DRIES, Sebastian, P., M. , LORENZ, Cristian , WIEMKER, Rafael , KLINDER, Tobias , FRANZ, Astrid, R. , RENISCH, Steffen
IPC分类号： G06T7/00 , A61B5/00
CPC分类号： G06T5/003 , G06T7/11 , G06T7/149 , G06T2207/10081 , G06T2207/20041 , G06T2207/20081 , G06T2207/20124 , G06T2207/20192 , G06T2207/30061
摘要： The present invention relates to an apparatus (1) for segmenting an object comprising sub-objects shown in an object image. The apparatus comprises a feature image generation unit (2) for generating a feature image showing features related to intermediate regions between the sub-objects and a segmentation unit (3) for segmenting the sub-objects by using the object image and the feature image. Preferentially, the feature image generation unit (2) is adapted for generating a feature image from the object image. In a further embodiment, the feature image generation unit (2) comprises a feature enhancing unit for enhancing features related to intermediate regions between the sub-objects in the object image.
摘要翻译：本发明涉及一种用于分割包含物体图像中所示的子对象的物体的装置（1）。该装置包括：特征图像生成单元，用于生成显示与子对象之间的中间区域相关的特征的特征图像和用于通过使用对象图像和特征图像来分割子对象的分割单元（3）。优选地，特征图像生成单元（2）适于从对象图像生成特征图像。在另一实施例中，特征图像生成单元（2）包括特征增强单元，用于增强与对象图像中的子对象之间的中间区域相关的特征。

10. 发明申请

WO2010086776A1 SYSTEM FOR PROVIDING LUNG VENTILATION INFORMATION 审中-公开
标题翻译：提供肺通气信息的系统
公开(公告)号：WO2010086776A1
公开(公告)日：2010-08-05
申请号：PCT/IB2010/050305
申请日：2010-01-25
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KABUS, Sven , OPFER, Roland , CARLSEN, Ingwer, C. , RENISCH, Steffen , SABCZYNSKI, Joerg , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , KLINDER, Tobias , LORENZ, Cristian , SCHADEWALDT, Nicole
发明人： KABUS, Sven , OPFER, Roland , CARLSEN, Ingwer, C. , RENISCH, Steffen , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , KLINDER, Tobias , LORENZ, Cristian , SCHADEWALDT, Nicole
IPC分类号： A61B5/08 , A61B6/03 , G06T7/00
CPC分类号： A61B6/5235 , A61B5/08 , A61B6/541 , G06T7/33 , G06T2207/10081 , G06T2207/30061
摘要： A system for displaying lung ventilation information, the system comprising an input (12) and a processing unit (15). The input being provided for receiving multiple CT images (71) of a lung, each CT image (71) corresponding to one phase of at least two different phases in a respiratory cycle. The processing unit (15) being configured to compare CT images (71) corresponding to different phases in the respiratory cycle for determining a deformation vector field for each phase, to generate for each phase a ventilation image (72) based on the corresponding deformation vector field, to spatially align the ventilation images (72), and to generate for at least one common position (62) in each one of the aligned ventilation images (72), a function (81) of a time course of a ventilation value for said common position (62), each ventilation value in the function (81) being based on the deformation vector fields corresponding to the aligned ventilation images (73).
摘要翻译：一种用于显示肺通气信息的系统，所述系统包括输入（12）和处理单元（15）。所述输入被提供用于接收肺的多个CT图像（71），每个CT图像（71）对应于呼吸周期中的至少两个不同相的一个相。所述处理单元（15）被配置为比较对应于呼吸周期中的不同相位的CT图像（71），以确定每个相位的变形矢量场，以根据相应的变形矢量为每个阶段生成通气图像（72）在空间上对准通气图像（72），并且为每个对齐的通气图像（72）中的至少一个公共位置（62）产生功能（81），其中通风值的时间过程为所述公共位置（62）中，所述功能（81）中的每个换气值基于对应于对齐的通气图像（73）的变形矢量场。

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