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1. 发明申请

WO2018089185A1 CHORDAE TENDINEAE MANAGEMENT DEVICES FOR USE WITH A VALVE PROSTHESIS DELIVERY SYSTEM AND METHODS OF USE THEREOF 审中-公开
标题翻译：用于瓣膜假体输送系统的CHORDAE TENDINEAE管理装置及其使用方法
公开(公告)号：WO2018089185A1
公开(公告)日：2018-05-17
申请号：PCT/US2017/057695
申请日：2017-10-20
申请人： MEDTRONIC VASCULAR INC.
发明人： DEVEREUX, Paul , FRISBY, Paraic , WHITE, Frank , KITT, Tomas , ANDERSON, Marc , CARROLL, Grainne , MCGUINNESS, Ciaran , JONES, Tim , GRIFFINE, Patrick
IPC分类号： A61F2/24 , A61M25/10 , A61B17/02
摘要： Embodiments hereof relate to methods of delivering a valve prosthesis to an annulus of a native valve of a heart, the native valve having chordae tendineae (CT). A chordae management catheter (520) is positioned within a ventricle of the heart, the chordae management catheter having a displacement component (530) at a distal end thereof. The displacement component has an annular shape and defines a central lumen therethrough. The displacement component is radially expanded to push chordae tendineae within the ventricle radially outward. A valve delivery system (2040) is introduced into the ventricle of the heart via a ventricular wall of the heart. The valve delivery system has the valve prosthesis (101) at a distal portion thereof. The valve delivery system is advanced through the central lumen of the radially expanded displacement component towards the annulus of the native valve of the heart. The valve prosthesis is deployed into apposition with the annulus of the native valve.
摘要翻译：本文的实施例涉及将瓣膜假体递送到心脏的天然瓣膜的瓣环的方法，所述天然瓣膜具有腱索（CT）。腱索管理导管（520）定位在心脏的心室内，腱索管理导管在其远端具有位移部件（530）。位移部件具有环形形状并且限定了贯穿其中的中心内腔。位移分量径向扩张以径向向外推动心室内的腱索。瓣膜输送系统（2040）通过心脏的心室壁被引入心脏的心室。瓣膜输送系统在其远侧部分具有瓣膜假体（101）。瓣膜输送系统通过径向膨胀的移位部件的中心腔朝向心脏自体瓣膜的环行进。瓣膜假体与天然瓣膜的瓣环部署在一起。

2. 发明申请

WO2021195005A1 TYNE DOCKING FOR PERCUTANEOUS CORONARY INTERVENTION ACCESS 审中-公开
公开(公告)号：WO2021195005A1
公开(公告)日：2021-09-30
申请号：PCT/US2021/023554
申请日：2021-03-23
申请人： MEDTRONIC VASCULAR, INC.
发明人： ANDERSON, Marc A. , MONTGOMERY, Stephen A. , DONEGAN, Michael J. , KEANE, Emma , KILLEEN, David , NOLAN, Shane , WHITE, Frank , RYAN, Raymond
IPC分类号： A61F2/24 , A61F2/2436 , A61F2002/9528 , A61F2220/0083
摘要： Aspects of the present disclosure provide a delivery device including a tubular outer jacket having a distal end and a tyne assembly including a shaft supporting at least one tyne. In some aspects, an inner jacket is positioned within the outer jacket, wherein the tyne assembly is positioned between the outer jacket and the inner jacket. The delivery device has a delivery configuration in which the tynes are maintained within the outer jacket and a deployed configuration in which the tynes extend from a distal end of the tubular outer jacket. Aspects of the disclosure also provide methods of conducting a percutaneous coronary intervention including utilizing one or more tyne assemblies to engage the tynes of each tyne assembly with the frame to maintain the position of the delivery device.

3. 发明申请

WO2019113194A1 ADJUSTABLE PROSTHETIC HEART VALVE 审中-公开
公开(公告)号：WO2019113194A1
公开(公告)日：2019-06-13
申请号：PCT/US2018/064052
申请日：2018-12-05
申请人： MEDTRONIC VASCULAR, INC.
发明人： WHITE, Frank , FRISBY, Paraic , KEOGH, James R.
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/0077 , A61F2/2418 , A61F2210/0004 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2220/0041 , A61F2230/0006 , A61F2230/0008 , A61F2230/0013 , A61F2250/0007 , A61F2250/0008 , A61F2250/001 , A61F2250/0067
摘要： A prosthetic valve including an inner frame, an outer frame, and a connection assembly interconnecting the frames. The inner frame defines an interior volume for receiving a valve structure within the interior volume. The outer frame surrounds the inner frame. The inner and outer frames are each configured to be transitionable between compressed and expanded conditions. The prosthetic heart valve provides a initial deployed state in which the inner and outer frames are in the expanded condition, and a radial shape of the outer frame is adjustable via the connection assembly to a final deployed state. A shape of the outer frame can be adjusted upon implant to enable radial anchoring at the native annulus, while addressing possible non-uniformities of the native annulus and possible anatomical concerns such as LVOT obstruction.

4. 发明申请

WO2018089184A1 VALVE DELIVERY SYSTEM HAVING AN INTEGRAL DISPLACEMENT COMPONENT FOR MANAGING CHORDAE TENDINEAE IN SITU AND METHODS OF USE THEREOF 审中-公开
标题翻译：具有用于管理原地胆碱的积分位移成分的阀输送系统及其使用方法
公开(公告)号：WO2018089184A1
公开(公告)日：2018-05-17
申请号：PCT/US2017/057683
申请日：2017-10-20
申请人： MEDTRONIC VASCULAR INC.
发明人： WHITE, Frank , JONES, Tim , ANDERSON, Marc , FRISBY, Paraic , KEANE, Emma , VAUGHAN, Brendan
IPC分类号： A61F2/24
摘要： Embodiments hereof relate to methods of delivering a valve prosthesis to an annulus of a native valve of a heart. A valve delivery system is introduced into a ventricle of the heart via a ventricular wall of the heart. The valve delivery system has a displacement component (1830) at the distal portion thereof. The valve prosthesis (101) is in a delivery configuration and the displacement component is in a delivery state in which the displacement component has a first outer diameter. While the valve prosthesis is in the delivery configuration, the displacement component of the valve delivery system is radially expanded into an expanded state in which the displacement component has a second outer diameter greater than the first outer diameter. The valve delivery system is advanced towards the annulus of the native valve of the heart with the displacement component in the expanded state to displace chordae tendineae.
摘要翻译：本文的实施例涉及将瓣膜假体递送到心脏的自体瓣膜的瓣环的方法。瓣膜输送系统通过心脏的心室壁被引入心脏的心室。瓣膜输送系统在其远端部分具有位移部件（1830）。瓣膜假体（101）处于输送构造中并且位移部件处于输送状态中，其中位移部件具有第一外径。当瓣膜假体处于输送构造中时，瓣膜输送系统的位移分量径向扩张到扩张状态，其中位移分量具有大于第一外径的第二外径。瓣膜输送系统朝向心脏原生瓣膜的环行进，其中位移部件处于扩张状态以置换腱索。

5. 发明申请

WO2017070243A1 SYSTEMS AND METHODS OF SEALING A DEPLOYED VALVE COMPONENT 审中-公开
标题翻译：密封部署的阀组件的系统和方法
公开(公告)号：WO2017070243A1
公开(公告)日：2017-04-27
申请号：PCT/US2016/057759
申请日：2016-10-19
申请人： MEDTRONIC VASCULAR INC.
发明人： BARRETT, Donna , ANDERSON, Marc , WHITE, Frank
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2418 , A61F2220/0016 , A61F2250/0069
摘要： A sealing system for sealing a valve component in a radially expanded deployed configuration includes a valve component and an expandable sealing component. The valve component includes a frame and a prosthetic valve coupled to the frame. The frame defines a central passage with the prosthetic valve disposed therein. The expandable sealing component includes a sealing frame and a skirt coupled to the sealing frame. The expandable sealing component is configured to be inserted in a compressed configuration within the central passage of the valve component with the valve component in the radially expanded deployed configuration. The expandable sealing component is configured to be radially expanded partially within the valve component, with a first portion disposed within the valve component and a second portion disposed longitudinally outside the valve component. The sealing frame may include a first ring and a second ring.
摘要翻译：用于密封处于径向展开展开构造的阀部件的密封系统包括阀部件和可膨胀密封部件。瓣膜部件包括框架和联接至框架的假体瓣膜。该框架限定了其中设置有人造瓣膜的中央通道。可膨胀密封部件包括密封框架和联接到密封框架的裙部。可膨胀密封部件构造成在瓣膜部件处于径向膨胀展开构型的情况下以压缩构造插入瓣膜部件的中心通道内。可膨胀密封部件构造成在阀部件内部分径向膨胀，其中第一部分设置在阀部件内，第二部分纵向设置在阀部件外部。密封框架可以包括第一环和第二环。

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