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1. 发明申请

WO2012154985A3 AV NODAL STIMULATION DURING ATRIAL TACHYARRHYTHMIA TO PREVENT INAPPROPRIATE THERAPY DELIVERY 审中-公开
标题翻译：急性心肌梗塞期间的AV NODAL刺激，以防止不准确的治疗方案
公开(公告)号：WO2012154985A3
公开(公告)日：2013-04-11
申请号：PCT/US2012037371
申请日：2012-05-10
申请人： MEDTRONIC INC , WARMAN EDUARDO N , BURNES JOHN E , MICHELS KOEN J , ZIEGLER PAUL D , KORNET LILIAN
发明人： WARMAN EDUARDO N , BURNES JOHN E , MICHELS KOEN J , ZIEGLER PAUL D , KORNET LILIAN
IPC分类号： A61N1/362 , A61N1/36
CPC分类号： A61N1/3622 , A61N1/36053 , A61N1/36114 , A61N1/3621 , A61N1/3624
摘要： The disclosure describes techniques for delivering electrical stimulation to decrease the ventricular rate response during an atrial tachyarrhythmia, such as atrial fibrillation. AV nodal stimulation is employed during an atrial tachyarrhythmia episode with rapid ventricular conduction to distinguish ventricular tachyarrhythmia from supraventricular tachycardia and thereby prevent delivering inappropriate therapy to a patient.
摘要翻译：本公开描述了用于递送电刺激以降低心房速发性心律失常（例如心房颤动）期间的心室率反应的技术。在室性快速性心律失常发作期间采用AV淋巴结刺激，其具有快速的心室传导以区分室上性快速性心律失常与室上性心动过速，从而阻止对患者递送不适当的治疗。

2. 发明申请

WO2009070675A2 DEVICE TO MONITOR GLUCOSE LEVELS AND ISCHEMIA 审中-公开
标题翻译：监测葡萄糖水平和ISCHEMIA的装置
公开(公告)号：WO2009070675A2
公开(公告)日：2009-06-04
申请号：PCT/US2008084863
申请日：2008-11-26
申请人： MEDTRONIC INC , BURNES JOHN E , WARMAN EDUARDO N
发明人： BURNES JOHN E , WARMAN EDUARDO N
IPC分类号： G06F19/00
CPC分类号： A61M5/1723 , A61M5/14244 , G06F19/3456
摘要： The disclosure relates to systems, methods, and devices for monitoring a patient's blood and cardiac condition. Patients with diabetes oftentimes wear diabetes management equipment (e.g., a glucose monitor, an external insulin pump, or a device having dual functionality). Such patients risk silent myocardial infarction. Herein described is regular cardiac ischemia/infarction monitoring - which if not monitored can lead to (silent) myocardial infarction. Moreover herein described are combined blood monitoring functionality and cardiac condition monitoring functionality via a single device, meaning that the patient is not required to wear additional equipment. Adding this functionality to already-existing equipment is significantly less invasive than requiring a patient to wear one piece of equipment to monitor his/her blood and a second piece of equipment to monitor his/her cardiac condition. This reduction in invasiveness can lead to significantly greater patient participation and compliance, which can improve health and save the lives of many patients.
摘要翻译：本公开涉及用于监测患者的血液和心脏状况的系统，方法和装置。患有糖尿病的患者通常佩戴糖尿病管理设备（例如，葡萄糖监测器，外部胰岛素泵或具有双重功能的装置）。这种患者存在无心肌梗塞的风险。这里描述的是常规心脏缺血/梗死监测 - 如果不监测可导致（沉默）心肌梗死。此外，这里描述的是通过单个装置组合的血液监测功能和心脏状态监测功能，这意味着患者不需要佩戴附加设备。将此功能添加到已存在的设备中比要求患者佩戴一件设备来监测他/她的血液和第二件设备来监测他/她的心脏状况的侵入性要小得多。这种侵袭性的降低可以导致患者参与和顺应性的显着增加，这可以改善健康并节省许多患者的生命。

3. 发明申请

WO2004093975A3 METHODS AND APPARATUS FOE DECREASING INCIDENCES OF EARLY RECURRENCE OF ATRIAL FIBRILLATION 审中-公开
标题翻译：方法和装置减少早期复发的复发
公开(公告)号：WO2004093975A3
公开(公告)日：2005-01-27
申请号：PCT/US2004011237
申请日：2004-04-09
申请人： MEDTRONIC INC , MUSLEY SHAELESH KUMA V , EULER DAVID E , WARMAN EDUARDO N
发明人： MUSLEY SHAELESH KUMA V , EULER DAVID E , WARMAN EDUARDO N
IPC分类号： A61N1/39
CPC分类号： A61N1/3956 , A61N1/395 , A61N1/3987
摘要： Implantable cardioverter/defibrillators (ICDs) providing atrial cardioversion/defibrillation (C/D) shock therapies in response to detected atrial tachyarrhythmias, particularly atrial fibrillation (AF) or in response to a patient command generated by a patient experiencing AF symptoms are disclosed. The early recurrence of atrial fibrillation (ERAF) following delivery of an atrial C/D shock is detected and delivery of any subsequent atrial C/D shock therapies is delayed for an ERAF sustained duration.
摘要翻译：公开了用于响应于检测到的心房快速性心律失常，特别是心房颤动（AF）或响应于患有AF症状的患者产生的患者指令的心房复律/除颤（C / D）休克疗法的植入式心律转复器/除颤器（ICD）。检测到心房C / D休克后出现心房颤动（ERAF）的早期复发，并且随后的心房C / D休克疗法的递送延迟了ERAF持续时间。

4. 发明申请

WO2008094818A3 SYSTEM AND METHOD FOR ISCHEMIA CLASSIFICATION WITH IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：具有可植入医疗装置的缺血分类系统和方法
公开(公告)号：WO2008094818A3
公开(公告)日：2008-10-09
申请号：PCT/US2008051981
申请日：2008-01-25
申请人： MEDTRONIC INC , SONG ZHENDONG , LU STEVEN NING , MUSLEY SHAILESH KUMAR V , WARMAN EDUARDO N
发明人： SONG ZHENDONG , LU STEVEN NING , MUSLEY SHAILESH KUMAR V , WARMAN EDUARDO N
IPC分类号： A61B5/0452
CPC分类号： A61B5/0452 , A61B5/7264 , Y10S128/92 , Y10S128/923
摘要： An implantable medical device monitors ST segment data collected from EGM. ST trends are established and monitored over time. The IMD is able to discern whether the data indicate supply ischemia, demand ischemia, or other physiological causes. The IMD is then able to provide appropriate information and alerts.
摘要翻译：植入式医疗设备监控从EGM收集的ST段数据。随着时间的推移，建立和监测ST趋势。 IMD能够辨别数据是否表明供应缺血，需求缺血或其他生理原因。 IMD然后能够提供适当的信息和警报。

5. 发明申请

WO2004103470B1 MEDICAL SYSTEM INCLUDING A NOVEL BIPOLAR PACING PAIR 审中-公开
标题翻译：医疗系统包括一个新的双极板对
公开(公告)号：WO2004103470B1
公开(公告)日：2005-06-02
申请号：PCT/US2004015152
申请日：2004-05-13
申请人： MEDTRONIC INC , BROWN MARK L , WARMAN EDUARDO N , GILLBERG JEFFREY M , BONNER MATTHEW D , MARSHALL MARK T , WHITMAN TERESA A
发明人： BROWN MARK L , WARMAN EDUARDO N , GILLBERG JEFFREY M , BONNER MATTHEW D , MARSHALL MARK T , WHITMAN TERESA A
IPC分类号： A61N1/05 , A61N1/368 , A61N1/37 , A61N1/39 , A61N1/00
CPC分类号： A61N1/057 , A61N1/0568 , A61N1/0573 , A61N1/368 , A61N1/3702 , A61N2001/0585
摘要： An implantable electrical medical system comprises a low voltage cathode electrode assembly, including a cathode surface adapted for intimate contact with electrically active tissue, and a low voltage anode electrode assembly, including an anode surface and a porous layer extending over the anode surface. The cathode surface and the anode surface function as a bipolar pair for pacing and the porous layer extending over the anode surface allows conduction therethrough and prevents the anode surface from contacting the electrically active tissue in order to prevent anodal stimulation.
摘要翻译：可植入电气医疗系统包括低压阴极电极组件，其包括适于与电活性组织紧密接触的阴极表面，以及包括阳极表面和在阳极表面上延伸的多孔层的低压阳极电极组件。阴极表面和阳极表面用作用于起搏的双极对，并且在阳极表面上延伸的多孔层允许通过其传导，并且防止阳极表面接触电活性组织以防止阳极刺激。

6. 发明申请

WO03053513B1 CARDIAC PACING METHOD AND SYSTEM 审中-公开
标题翻译： CARDIAC PACING方法和系统
公开(公告)号：WO03053513B1
公开(公告)日：2004-04-08
申请号：PCT/US0241296
申请日：2002-12-20
申请人： MEDTRONIC INC
发明人： HESS MICHAEL F , WARMAN EDUARDO N , BROWN MARK L , MEHRA RAHUL , SHETH NIRAV V , RITSCHER DAVID
IPC分类号： A61N1/365 , A61N1/362 , A61N1/39
CPC分类号： A61N1/3622 , A61N1/3624
摘要： AbstractThe invention relates to the use of atrial pacing therapies to treat atrial tachycardia (AT). When an AT episode is detected, an implantable medical device applies an ATP therapy. If the AT episode persists, the ATP therapy may be automatically reapplied at a later time during the course of the same AT episode. In particular, previously used ATP therapies are reapplied when episodic conditions, such as cycle length or cycle regularity, change. Although a particular ATP therapy initially may be unsuccessful in terminating the AT, it may prove successful when the cycle length or regularity of the atrial rhythm changes. As the rhythm slows down, the AT may be more responsive to ATP therapies that were previously unsuccessful. As a result, potentially efficacious ATP therapies can be reapplied to terminate AT episodes, and reduce the number of episodes that require more aggressive termination by painful, atrial shocks.
摘要翻译：摘要本发明涉及心房起搏疗法治疗房性心动过速（AT）的应用。当检测到AT发作时，可植入医疗装置应用ATP疗法。如果AT发作持续存在，ATP疗法可能会在相同的AT发作过程中的较晚时间自动重新应用。特别是，当诸如循环长度或循环规律性等情况时，先前使用的ATP疗法将被重新应用。尽管特定的ATP疗法最初可能不能终止AT，但是当心房节律的周期长度或规律性发生变化时，可能会成功。随着节奏减慢，AT可能对以前不成功的ATP疗法更有反应。因此，可以重新应用潜在有效的ATP疗法来终止AT发作，并通过痛苦的心房休克减少需要更积极终止的发作次数。

7. 发明申请

WO2006009729A2 METHODS AND DEVICES FOR OCCLUSION OF AN ATRIAL APPENDAGE 审中-公开
标题翻译：方法和装置用于消除ATRIAL附件
公开(公告)号：WO2006009729A2
公开(公告)日：2006-01-26
申请号：PCT/US2005021107
申请日：2005-06-16
申请人： MEDTRONIC INC
发明人： LUTTERMAN ALISON , ROTHSTEIN PAUL T , FRANCISCHELLI DAVID E , BRISCOE RODERICK E , LEUER LEONARD H , HAEG DANIEL C , DAIGLE TOMAS P , FALKNER PHILIP C , WARMAN EDUARDO N , HETTRICK DOUGLAS A , STEINBRINK MARIE T , KIM DAVID J S , STEWART MARK T , CHRISTIAN STEVEN C , OLIG CHRISTOPHER P
IPC分类号： A61B17/10
CPC分类号： A61B17/0057 , A61B17/12013 , A61B17/122 , A61B17/1285 , A61B90/39 , A61B2017/00243 , A61B2017/00575 , A61B2017/12018 , A61B2017/306
摘要： Some embodiments of the invention provide a system for occluding a left atrial appendage of a patient. Some embodiments of the system can include a ring occluder that can be positioned around the left atrial appendage and a ring applicator to position the ring occluder with respect to the left atrial appendage. Other embodiments of the invention provide a clip occluder that can be positioned around the left atrial appendage. A clip applicator can position the clip occluder with respect to the left atrial appendage.
摘要翻译：本发明的一些实施例提供一种用于闭塞患者左心耳的系统。该系统的一些实施例可以包括可以围绕左心耳定位的环封闭器和环施加器来相对于左心耳定位环封闭器。本发明的其它实施例提供可围绕左心耳定位的夹子封堵器。夹子施放器可以相对于左心耳定位夹子封堵器。

8. 发明申请

WO2004071316A9 ABLATION SYSTEM AND METHOD OF USE 审中-公开
标题翻译：吸收系统及其使用方法
公开(公告)号：WO2004071316A9
公开(公告)日：2004-10-28
申请号：PCT/US2004002739
申请日：2004-01-30
申请人： MEDTRONIC INC
发明人： FRANCISCHELLI DAVID E , WARMAN EDUARDO N , HARDER JUSTIN A , JAHNS SCOTT E , LUTTERMAN ALISON
IPC分类号： A61B18/12 , A61B18/14
CPC分类号： A61B18/1206 , A61B18/1442 , A61B2018/0016 , A61B2018/00351 , A61B2018/00363 , A61B2018/00577 , A61B2018/00702 , A61B2018/00761 , A61B2018/00791 , A61B2018/00875 , A61B2018/00886 , A61B2018/1467 , A61B2218/002

9. 发明申请

WO0230310A9 HEART WALL ABLATION/MAPPING CATHETER AND METHOD 审中-公开
标题翻译：心墙吸引/绘图导管及方法
公开(公告)号：WO0230310A9
公开(公告)日：2003-02-20
申请号：PCT/US0130578
申请日：2001-10-01
申请人： MEDTRONIC INC
发明人： STEWART MARK T , GOODE JOHNSON E , SPECKIEN JAMES N , TAUBE MARK A , WARMAN EDUARDO N
IPC分类号： A61B17/00 , A61B18/14 , A61M25/01
CPC分类号： A61M25/0147 , A61B18/1492 , A61B2017/00243 , A61B2018/00916 , A61M25/0152 , A61M2025/015 , A61M2025/0161
摘要： Steerable electrophysiology catheters for use in mapping and/or ablation of accessory pathways in myocardial tissue of the heart wall and methods of use thereof are disclosed. The catheter comprises a catheter body and handle, the catheter body having a proximal section and a distal section and manipulators that enable the deflection of a distal segment of the distal tip section with respect to the independently formed curvature of a proximal segment of the distal tip section through a bending or knuckle motion of an intermediate segment between the proximal and distal segments. A wide angular range of deflection within a very small curve or bend radius in the intermediate segment is obtained.
摘要翻译：公开了用于在心壁的心肌组织中附着途径的测绘和/或消融中的可操纵的电生理学导管及其使用方法。导管包括导管主体和手柄，导管主体具有近端部分和远端部分以及操纵器，其能够相对于远端尖端的近端段的独立形成的曲率偏转远侧末端部分的远侧部分通过近端段和远端段之间的中间段的弯曲或转向关节运动。获得在中间段内的非常小的曲线或弯曲半径内的宽的角度范围的偏转。

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