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1. 发明申请

WO2012141776A1 ESTIMATING THE VOLUME OF FLUID IN THERAPEUTIC FLUID DELIVERY DEVICE RESERVOIR 审中-公开
标题翻译：估计治疗流体装置储存中的液体体积
公开(公告)号：WO2012141776A1
公开(公告)日：2012-10-18
申请号：PCT/US2012/023213
申请日：2012-01-31
申请人： MEDTRONIC, INC. , KALPIN, Scott L. , BAUDINO, Michael D.
发明人： KALPIN, Scott L. , BAUDINO, Michael D.
IPC分类号： A61M5/142
CPC分类号： A61M5/14276 , A61M5/152 , A61M2005/14204 , A61M2205/3334
摘要： A number of parameters related to the operation of a fluid delivery device are determined based on pressures within the device sensed using multiple pressure sensors. In one example, the volume of therapeutic fluid within a reservoir of a fluid delivery device is estimated based on a measured pressure differential. In another example, the rate at which a therapeutic fluid is added to or removed from the reservoir is estimated based on the measured pressure differential.
摘要翻译：基于使用多个压力传感器感测的装置内的压力来确定与流体输送装置的操作有关的许多参数。在一个示例中，基于测量的压力差估计流体输送装置的储存器内的治疗流体的体积。在另一个实例中，基于所测量的压力差来估计加入到储存器中或从贮存器移除的治疗流体的速率。

2. 发明申请

WO2011129911A1 PRESSURE-BASED TEMPERATURE ESTIMATION FOR IMPLANTABLE FLUID DELIVERY DEVICES 审中-公开
标题翻译：基于压力的温度估计可植入流体装置
公开(公告)号：WO2011129911A1
公开(公告)日：2011-10-20
申请号：PCT/US2011/023104
申请日：2011-01-31
申请人： MEDTRONIC, INC. , KALPIN, Scott L.
发明人： KALPIN, Scott L.
IPC分类号： A61M5/148 , A61M5/142
CPC分类号： A61M5/14276 , A61M2205/33 , A61M2205/3331 , A61M2205/3368 , A61M2205/3379 , G06F19/00 , G06F19/3468
摘要： A number of parameters related to the operation of a fluid delivery device are determined based on a pressure within the device sensed using a pressure sensor (100). In one example, the volume of therapeutic fluid added to or removed from a reservoir (34) of a fluid delivery device is determined based on a sensed pressure of the reservoir. In another example, the volume of therapeutic fluid added to or removed from the reservoir is determined based on a sensed pressure of a refill port assembly of the device. In another example, an initial temperature of the reservoir as a therapeutic fluid is removed from the reservoir is estimated based on a sensed pressure within the device. In another example, a temperature of a therapeutic fluid added to the reservoir is estimated based on a sensed pressure within the device.
摘要翻译：基于使用压力传感器（100）感测的装置内的压力来确定与流体输送装置的操作有关的多个参数。在一个示例中，基于感测到的储存器的压力来确定添加到流体输送装置的储存器（34）或从其移除的治疗流体的体积。在另一个实例中，基于装置的再充填端口组件的检测到的压力来确定添加到储存器中或从储存器移除的治疗流体的体积。在另一个实例中，基于所检测到的装置内的压力来估计储存器作为治疗流体的初始温度从储存器中移出。在另一个实例中，基于装置内感测到的压力来估计添加到储存器中的治疗流体的温度。

3. 发明申请

WO2011119416A1 METHOD AND APPARATUS FOR GUIDING AN EXTERNAL NEEDLE TO AN IMPLANTABLE DEVICE 审中-公开
标题翻译：用于将外部指针引导到可植入装置的方法和装置
公开(公告)号：WO2011119416A1
公开(公告)日：2011-09-29
申请号：PCT/US2011/028915
申请日：2011-03-18
申请人： MEDTRONIC, INC. , KALPIN, Scott L. , BZOSTEK, Andrew M. , HARTMANN, Steven L. , KOENIG, Matthew W. , JACOBSEN, Brad , SARKINEN, Scott A. , BOROWITZ, Peter J. , JASCOB, Bradley A.
发明人： KALPIN, Scott L. , BZOSTEK, Andrew M. , HARTMANN, Steven L. , KOENIG, Matthew W. , JACOBSEN, Brad , SARKINEN, Scott A. , BOROWITZ, Peter J. , JASCOB, Bradley A.
IPC分类号： A61B19/00 , A61M5/42 , A61M5/142
CPC分类号： A61M5/14276 , A61B34/20 , A61B34/25 , A61B90/11 , A61B2034/2051 , A61B2090/0811 , A61B2090/3958 , A61M5/427 , A61M2039/0081 , A61M2039/0238
摘要： A support tool or a supply assembly that delivers a functional fluid to a patient includes an antenna array for receiving or sensing a navigation field. The navigation field can be generated from a localizer. The localizer can be incorporated or included in an implanted device.
摘要翻译：将功能流体递送到患者的支撑工具或供应组件包括用于接收或感测导航区域的天线阵列。可以从定位器生成导航字段。定位器可以并入或包括在植入装置中。

4. 发明申请

WO2009131718A1 EXTERNAL STIMULUS FOR ESTABLISHING COMMUNICATION WITH IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：用于建立具有可植入医疗设备的通信的外部刺激
公开(公告)号：WO2009131718A1
公开(公告)日：2009-10-29
申请号：PCT/US2009/030833
申请日：2009-01-13
申请人： MEDTRONIC, INC. , KALPIN, Scott L. , MITCHELL, William J. , LEONG, Patrick S.
发明人： KALPIN, Scott L. , MITCHELL, William J. , LEONG, Patrick S.
IPC分类号： A61N1/372 , A61B5/00 , H04L9/00 , G06F21/00
CPC分类号： H04L63/0492 , A61B5/0031 , A61N1/37252 , G06F19/00 , G16H40/40 , H04L63/08
摘要： The present invention relates to systems, devices and methods for accessing an implantable medical device when the security key is not known. The systems, methods and devices help to access an implantable medical device through a back door to permit non-secure communications. The systems, devices, and methods require short range external stimulus to indicate to the implantable medical device that a valid communication is about to be received.
摘要翻译：本发明涉及当安全密钥未知时用于访问可植入医疗设备的系统，设备和方法。系统，方法和设备有助于通过后门访问植入式医疗设备以允许非安全通信。系统，装置和方法需要短距离外部刺激以向可植入医疗装置指示即将接收有效的通信。

5. 发明申请

WO2011126694A1 APPARATUS FOR GUIDING AN EXTERNAL NEEDLE TO AN IMPLANTABLE DEVICE 审中-公开
标题翻译：用于将外部指针引导到可植入装置的装置
公开(公告)号：WO2011126694A1
公开(公告)日：2011-10-13
申请号：PCT/US2011/028856
申请日：2011-03-17
申请人： MEDTRONIC, INC. , KALPIN, Scott L. , BZOSTEK, Andrew M. , HARTMANN, Steven L. , KOENIG, Matthew W. , JACOBSEN, Brad , SARKINEN, Scott A. , BOROWITZ, Peter J. , JASCOB, Bradley A.
发明人： KALPIN, Scott L. , BZOSTEK, Andrew M. , HARTMANN, Steven L. , KOENIG, Matthew W. , JACOBSEN, Brad , SARKINEN, Scott A. , BOROWITZ, Peter J. , JASCOB, Bradley A.
IPC分类号： A61B19/00
CPC分类号： A61B5/061 , A61B34/20 , A61B2034/2051 , A61B2034/2072 , A61M5/14276 , A61M39/0208 , A61M39/04 , A61M2039/0081 , A61M2039/0238 , A61M2209/045
摘要： A system can include an implantable device, an instrument, a display device and a processor. The implantable device can include a port and a localizer for generating a navigation field. The instrument can include a tracking device for sensing the navigation field. The processor can be operably coupled to the tracking and display devices and operable to determine a real-time location of the instrument relative to the port and a trajectory of the instrument relative to an insertion axis of the port.
摘要翻译：系统可以包括可植入装置，仪器，显示装置和处理器。可植入装置可以包括用于产生导航场的端口和定位器。仪器可以包括用于感测导航场的跟踪装置。处理器可以可操作地耦合到跟踪和显示设备并且可操作以确定仪器相对于端口的实时位置以及仪器相对于端口的插入轴线的轨迹。

6. 发明申请

WO2010059588A1 PRESSURE BASED REFILL STATUS MONITOR FOR IMPLANTABLE PUMPS 审中-公开
标题翻译：基于压力的灌注状态监测器
公开(公告)号：WO2010059588A1
公开(公告)日：2010-05-27
申请号：PCT/US2009/064693
申请日：2009-11-17
申请人： MEDTRONIC, INC. , KALPIN, Scott L.
发明人： KALPIN, Scott L.
IPC分类号： A61M5/142 , A61M5/168
CPC分类号： A61M5/1684 , A61M5/14276 , A61M5/16809 , A61M2205/3331 , A61M2205/3389 , A61M2205/3396 , A61M2205/3592 , A61M2205/502 , A61M2205/702 , A61M2209/045 , G01F23/14
摘要： The present invention includes systems for detecting fluid flow into or out of a port chamber or reservoir of an implantable medical device utilizing a pressure sensor and calculating the fluid status of the reservoir. The system detects characteristic pressure profiels associated with fluid flowing into the medical device, out of the medical device, and also whether one or both of the port chamber or reservoir are substantially empty or substantially full. In addition, the present invention may generate a sensor cue to a clinican to indicate the fluid status.
摘要翻译：本发明包括用于利用压力传感器和计算储存器的流体状态来检测流入或流出可植入医疗装置的口腔或容器的流体的系统。该系统检测与流入医疗装置的流体相关联的特征压力分布，离开医疗装置，以及端口腔或储存器中的一个或两个是基本上空的还是基本上满的。此外，本发明可以产生临床医生的传感器提示以指示流体状态。

7. 发明申请

WO2011119417A1 METHOD AND APPARATUS FOR GUIDING AN EXTERNAL NEEDLE TO AN IMPLANTABLE DEVICE 审中-公开
标题翻译：用于将外部指针引导到可植入装置的方法和装置
公开(公告)号：WO2011119417A1
公开(公告)日：2011-09-29
申请号：PCT/US2011/028916
申请日：2011-03-18
申请人： MEDTRONIC, INC. , KALPIN, Scott L. , BOROWITZ, Peter J. , BZOSTEK, Andrew M. , HARTMANN, Steven L. , JACOBSEN, Brad , KOENIG, Matthew W. , SARKINEN, Scott A. , JASCOB, Bradley A.
发明人： KALPIN, Scott L. , BOROWITZ, Peter J. , BZOSTEK, Andrew M. , HARTMANN, Steven L. , JACOBSEN, Brad , KOENIG, Matthew W. , SARKINEN, Scott A. , JASCOB, Bradley A.
IPC分类号： A61B19/00 , A61M5/42 , A61M5/142
CPC分类号： A61M5/427 , A61B34/20 , A61B34/25 , A61B90/11 , A61B2034/2051 , A61B2090/0811 , A61B2090/3958 , A61M5/14276
摘要： A support tool for a supply assembly delivers a functional fluid to an implantable medical device. The supply assembly defines a supply axis. The support tool includes a support member defining an opening. The opening has a support axis, and the opening is configured to receive the supply assembly. The support member includes a three dimensionally contoured nesting surface that conforms to a corresponding three dimensionally contoured surface of the supply assembly. The corresponding surface of the supply assembly nests against the nesting surface to support the supply assembly such that the supply axis remains substantially fixed relative to and aligned with the support axis
摘要翻译：用于供应组件的支撑工具将功能流体输送到可植入医疗装置。供应组件定义供应轴。支撑工具包括限定开口的支撑构件。开口具有支撑轴，并且开口构造成接收供应组件。支撑构件包括符合供应组件的相应三维轮廓表面的三维轮廓的嵌套表面。供应组件的对应表面抵靠嵌套表面支撑供应组件，使得供给轴线相对于支撑轴线保持基本上固定，并且与支撑轴线对准

8. 发明申请

WO2009039075A1 APPARATUS FOR ALIGNING NEEDLE WITH PORT OF INFUSION DEVICE 审中-公开
标题翻译：用于用针头注射输液装置的装置
公开(公告)号：WO2009039075A1
公开(公告)日：2009-03-26
申请号：PCT/US2008/076489
申请日：2008-09-16
申请人： MEDTRONIC, INC. , BZOSTEK, Andrew M. , HARTMANN, Steven L. , KALPIN, Scott L.
发明人： BZOSTEK, Andrew M. , HARTMANN, Steven L. , KALPIN, Scott L.
IPC分类号： A61M5/42 , A61M5/142 , A61B5/06
CPC分类号： A61M5/427 , A61B5/06 , A61B5/4839 , A61B5/6865 , A61M5/14276 , A61M2205/3523 , A61M2205/3569 , A61M2205/583 , A61M2205/6018 , A61M2209/045
摘要： A needle apparatus (20) for aligning a needle (50) with a port of an implantable infusion device includes a needle anchoring portion (26) configured to axially fix the apparatus relative to a needle to be inserted into the port. The needle apparatus further includes a port locating portion (200) fixable relative to the needle anchoring portion. The port locating portion includes a port location signal receiver module (25) for receiving a signal from an implantable infusion device regarding the location of the port of the infusion device.
摘要翻译：用于将针（50）与可植入输注装置的端口对准的针装置（20）包括针固定部分（26），其被构造成相对于插入端口的针轴固定装置。针装置还包括可相对于针固定部固定的端口定位部分（200）。端口定位部分包括端口位置信号接收器模块（25），用于从植入式输注装置接收关于输注装置的端口的位置的信号。

9. 发明申请

WO2008140901A1 SEPTUM PORT LOCATOR SYSTEM AND METHOD FOR AN IMPLANTABLE THERAPEUTIC SUBSTANCE DELIVERY DEVICE 审中-公开
标题翻译： SEPTUM端口定位系统和可植入式治疗物质输送装置的方法
公开(公告)号：WO2008140901A1
公开(公告)日：2008-11-20
申请号：PCT/US2008/061089
申请日：2008-04-22
申请人： MEDTRONIC, INC. , HOENDERVOOGT, Jason J. , KALPIN, Scott L. , SARKINEN, Scott A.
发明人： HOENDERVOOGT, Jason J. , KALPIN, Scott L. , SARKINEN, Scott A.
IPC分类号： A61M5/42 , A61M5/142
CPC分类号： A61M5/427 , A61B2034/2051 , A61M5/14276 , A61M2209/045
摘要： An implantable medical device system (20) includes an implantable device (24) and an external locator device (26) for percutaneously locating a port opening (28,30) of the implantable device. The implantable device includes a port chamber (28) forming a port opening, a septum (86) sealing the port chamber relative to an exterior of the device, and a coil (32) positioned at a known location relative to the port opening. The locator device includes a controller (134), at least one X-loop (150) electrically coupled to the ' controller and oriented along a first major axis, and at least one Y-loop (160) electrically coupled to thef controller and oriented along a second major axis differing from the first major axis. The system is configured such that when the locator is spatially proximate the coil, an induced voltage in at least the Y-loop (s) is read by the controller to indicate a location of the coil relative to the locator device.
摘要翻译：植入式医疗装置系统（20）包括可植入装置（24）和用于经皮定位可植入装置的端口开口（28,30）的外部定位装置（26）。可植入装置包括形成端口的端口室（28），密封端口室相对于装置外部的隔膜（86）和位于相对于端口开口的已知位置的线圈（32）。所述定位装置包括控制器（134），至少一个电耦合到所述“控制器并沿着第一长轴定向”的X环（150），以及至少一个电耦合到所述控制器的Y形环（160）沿着与第一长轴不同的第二长轴。该系统配置成使得当定位器在空间上靠近线圈时，至少Y形回路中的感应电压由控制器读取以指示线圈相对于定位器装置的位置。

10. 发明申请

WO2013002846A1 DEVICES AND METHODS FOR DETECTING CATHETER COMPLICATIONS 审中-公开
标题翻译：用于检测导管连接的装置和方法
公开(公告)号：WO2013002846A1
公开(公告)日：2013-01-03
申请号：PCT/US2012/023277
申请日：2012-01-31
申请人： MEDTRONIC, INC. , KALPIN, Scott L. , MIESEL, Keith A. , SOLEFACK, Lucien Bell
发明人： KALPIN, Scott L. , MIESEL, Keith A. , SOLEFACK, Lucien Bell
IPC分类号： A61M5/168 , A61M5/172 , A61M5/142 , A61M27/00
CPC分类号： A61M5/14276 , A61M5/16854 , A61M5/16859 , A61M5/1723 , A61M27/006 , A61M2005/1726 , A61M2025/0003 , A61M2202/0464 , A61M2205/3331 , A61M2205/3344 , A61M2205/3355 , A61M2210/0693 , A61M2230/005 , A61M2230/04 , A61M2230/06 , A61M2230/40 , A61M2230/42 , A61M2230/63
摘要： A method for determining status of an implanted catheter includes acquiring raw pressure data ( 20 ) from a pressure sensor of in an implantable infusion device. The pressure sensor is in communication with a lumen of the catheter operably coupled to the infusion device. The catheter has a delivery region, in communication with the lumen, intended to be positioned in a fluid- filled target location of a patient. The method further includes filtering the raw pressure data to remove the DC component, leaving the AC component within a relevant physiological frequency range; rectifying the AC component to produce a rectified pressure signal; calculating a mean magnitude of the rectified signal; and determining whether the mean magnitude is below a predetermined threshold. If the mean magnitude is below the threshold, the catheter is determined to be in a state other than a normal state.
摘要翻译：用于确定植入导管的状态的方法包括从可植入输注装置中的压力传感器获取原始压力数据（20）。压力传感器与可操作地连接到输注装置的导管的内腔连通。导管具有与内腔连通的输送区域，旨在定位在患者的流体填充的目标位置。该方法还包括过滤原始压力数据以去除DC分量，将AC分量留在相关的生理频率范围内; 整流交流分量以产生整流压力信号; 计算整流信号的平均幅度; 以及确定平均幅度是否低于预定阈值。如果平均值低于阈值，则确定导管处于正常状态以外的状态。

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