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1. 发明申请

WO2017220317A1 SUPPLY UNIT FOR MEDICAL OXYGEN STORED IN LIQUID FORM AND METHOD OF ESTIMATING THE LEVEL OF LIQUID OXYGEN IN SUCH A SUPPLY UNIT 审中-公开
标题翻译：以液体形式储存医用氧的供应单元和估算该A供应单元中液体氧水平的方法
公开(公告)号：WO2017220317A1
公开(公告)日：2017-12-28
申请号：PCT/EP2017/063583
申请日：2017-06-02
申请人： LINDE AG
发明人： BAUSE, Matthias , HÄUSSERMANN, Sabine , SCHMEHL, Wolfgang
IPC分类号： F17C7/02 , F17C13/08 , G01F22/00 , G01F22/02 , A61M16/06 , A61M16/20 , G01F15/00
CPC分类号： A61M16/204 , A61M16/0672 , A61M16/1005 , A61M16/209 , A61M2205/18 , A61M2205/3334 , A61M2205/3396 , A61M2205/502 , A61M2230/202 , A61M2230/205 , F17C6/00 , F17C7/02 , F17C9/00 , F17C13/025 , F17C13/084 , F17C2201/056 , F17C2201/058 , F17C2205/037 , F17C2221/011 , F17C2223/0161 , F17C2223/033 , F17C2250/032 , F17C2250/0421 , F17C2250/043 , F17C2250/0443 , F17C2250/0473 , F17C2250/0491 , F17C2250/0495 , F17C2270/02 , G01F15/005 , G01F22/02
摘要： The invention provides a supply unit (10, 20) for liquid medical oxygen, the supply unit (10, 20) including a reservoir (11, 21) adapted to be filled with the liquid medical oxygen, at least one dispensing valve (13, 19, 23) in fluid communication with the reservoir (11, 21) and operable by a user of the supply unit (10, 20), and an overpressure valve (14, 24) in fluid communication with the reservoir (11, 21) and adapted to open in order to vent the reservoir (11, 21) when a pressure in the reservoir (11, 21) exceeds a given value. The mobile supply unit (10, 20) includes estimating means adapted to provide a value corresponding to an amount of the liquid medical oxygen spent from the reservoir (11, 21) since an initial timepoint at least on the basis of a value corresponding to an initial amount of the liquid medical oxygen in the reservoir (11, 21) at the initial timepoint, a value corresponding to one or more valve settings of the dispensing valve or valves (13, 19, 23) since the initial timepoint, and a value corresponding to one or more durations during which the overpressure valve (14, 24) was open in order to vent the reservoir (11, 21) since the initial timepoint. A corresponding method is also part of the present invention.
摘要翻译：本发明提供一种用于液体医用氧气的供应单元（10,20），所述供应单元（10,20）包括适于填充所述液体医用氧气的贮存器（11,21）与储存器（11,21）流体连通并且可由供应单元（10,20）的使用者操作的至少一个分配阀（13,19,23）以及流体连通的过压阀（14,24）与贮存器（11,21）并且适于打开，以便当贮存器（11,21）中的压力超过给定值时排出贮存器（11,21）。所述移动式供应单元（10,20）包括估算装置，所述估算装置适于提供与从所述储存器（11,21）花费的液体医用氧气的量相对应的值，所述估算装置自初始时间点至少基于对应于在初始时间点储存器（11,21）中的液体医疗氧气的初始量，与从初始时间点开始的一个或多个分配阀（13,19,23）的一个或多个阀设定相对应的值，对应于过压阀（14,24）打开时的一个或多个持续时间，以便从初始时间点开始排放储液器（11,21）。相应的方法也是本发明的一部分。

2. 发明申请

WO2013140346A1 TREATMENT SOLUTION DELIVERY IN AN EXTRACORPOREAL BLOOD TREATMENT APPARATUS 审中-公开
标题翻译：治疗解决方案提供在一个额外的血液治疗设备
公开(公告)号：WO2013140346A1
公开(公告)日：2013-09-26
申请号：PCT/IB2013/052202
申请日：2013-03-20
申请人： GAMBRO LUNDIA AB
发明人： POUCHOULIN, Dominique
IPC分类号： A61M1/16
CPC分类号： A61M1/1605 , A61M1/16 , A61M1/1601 , A61M1/1613 , A61M1/1643 , A61M2205/3334 , A61M2205/3379 , A61M2205/3393 , A61M2205/3396 , A61M2205/50
摘要： Blood treatment apparatus and methods of using the same are described herein that include two or more intermediate containers located between a treatment solution source and a port through which the treatment solution is to be delivered with the blood treatment apparatus. The weight of the intermediate containers is measured and used to control the refilling and emptying of treatment solution in the intermediate containers.
摘要翻译：本文描述了血液处理装置及其使用方法，其包括位于处理溶液源和处理溶液将通过血液处理装置输送的口之间的两个或更多个中间容器。中间容器的重量被测量并用于控制中间容器中处理溶液的再填充和排空。

3. 发明申请

WO2011077205A1 METHOD AND APPARATUS FOR CONTROLLING A FLUID FLOW RATE IN A FLUID TRANSPORT LINE OF A MEDICAL DEVICE 审中-公开
标题翻译：用于控制医疗装置的流体输送管线中的流体流量的方法和装置
公开(公告)号：WO2011077205A1
公开(公告)日：2011-06-30
申请号：PCT/IB2010/003051
申请日：2010-11-29
申请人： GAMBRO LUNDIA AB , BENE, Bernard
发明人： BENE, Bernard
IPC分类号： A61M1/36 , A61M1/34
CPC分类号： A61M1/342 , A61M1/1601 , A61M1/3434 , A61M1/3437 , A61M1/3441 , A61M2205/3396 , A61M2205/702 , F17D3/00 , Y10T137/0324 , Y10T137/85986
摘要： An apparatus for controlling a fluid flow rate in a fluid transport line (12, 15, 16) of a medical device, comprising at least a first pump, at least a first chamber (29, 29a) for collecting the fluid, at least a sensor for providing a first value (v1) correlated to the amount of fluid in the first chamber (29, 29a), and a control device (21, 21 a) configured for receiving a second value representative of the fluid flow rate through the first pump (18, 18a) and for correlating the second value with the first value (v1 ) in order to obtain an accuracy check of the second value. A method for controlling a fluid flow rate in a fluid transport line (12, 15, 16) of a medical device is also disclosed, comprising the steps of pumping a fluid, collecting the fluid in a first chamber (29, 29a), sensing a first value (v1) correlated to the amount of fluid in the first chamber (29, 29a), and detecting and sending a second value representative of the fluid flow rate through the first pump (18, 18a) to a control device (21, 21a), sending the first value (v1) to the control device (21, 21 a), and correlating the second value with the first value (v1) in order to obtain an accuracy check.
摘要翻译：一种用于控制医疗装置的流体输送管线（12,15,16）中的流体流速的装置，包括至少第一泵，至少第一室（29,29a），用于收集流体，至少一个传感器，用于提供与第一腔室（29,29a）中的流体量相关的第一值（v1）;以及控制装置（21,21a），其被配置用于接收代表流过第一腔室泵（18,18a），并且用于使第二值与第一值（v1）相关，以便获得第二值的精度检查。还公开了一种用于控制医疗装置的流体输送管线（12,15,16）中的流体流速的方法，包括以下步骤：泵送流体，将流体收集在第一腔室（29,29a）中，感测与第一腔室（29,29a）中的流体量相关联的第一值（v1），以及检测和发送代表通过第一泵（18,18a）的流体流量的第二值到控制装置（21），21a），将第一值（v1）发送到控制设备（21,21a），并且将第二值与第一值（v1）相关联以获得精度检查。

4. 发明申请

WO2004112869A1 DISPOSITIF DE TRAITEMENT DE SANG PAR CIRCULATION EXTRACORPORELLE A VIDANGE AUTOMATIQUE DE LIQUIDE USE 审中-公开
标题翻译：使用超声波循环和自动流体液体排出的血液加工装置
公开(公告)号：WO2004112869A1
公开(公告)日：2004-12-29
申请号：PCT/IB2004/002024
申请日：2004-06-17
申请人： GAMBRO LUNDIA AB , CHEVALLET, Jacques
发明人： CHEVALLET, Jacques
IPC分类号： A61M1/16
CPC分类号： A61M1/16 , A61M1/1605 , A61M1/1613 , A61M1/1643 , A61M2205/3334 , A61M2205/3393 , A61M2205/3396
摘要： L'invention concerne un dispositif de traitement de sang par circulation extracorporelle comportant un filtre (2) avec une membrane semi -perméable (5); un circuit sang (7, 3, 6); un circuit dialysat comportant la chambre secondaire du filtre (4) et au moins une ligne de vidange (8) pour la circulation du liquide usé destiné à sortir du filtre et destiné à aller vers un égout (9); un premier sac (11) en communication de fluide avec la ligne de vidange ; au moins un premier moyen de pesage gravimétrique (21) associé au premier sac, des moyens de réglage de débit de fluide actifs sur la ligne de vidange (31, 32, 33); une unité de contrôle (41) reliée au premier moyen de pesage gravimétrique et aux moyens de réglage de débit de fluide ; un second sac (12) en communication de fluide avec la ligne de vidange, l'unité de contrôle étant capable de recevoir les signaux de poids du premier moyen de pesage gravimétrique et de commander les moyens de réglage pour charger de liquide un des sacs pendant que l'autre sac se décharge de liquide, et vice-versa. L'invention concerne également une ligne jetable de vidange pour l'utilisation dans un dispositif de traitement.
摘要翻译：本发明涉及一种使用体外循环并包含具有半透膜（5）的过滤器（2）的血液处理装置。血液回路（7,3,6）; 透析液回路，其包括二次过滤室（4）和至少一个排出管线（8），用于将废液从过滤器排放到排水管（9）中; 与所述排水管道流体连通的第一袋（11）; 至少一个连接到第一袋的第一重量称重装置（21），用于控制排放管线（31,32,33）上的活性流体流动的装置; 连接到第一重量计量装置和流体流量控制装置的控制单元（41）与所述排水管线流体连通的第二袋（12），其中所述控制单元可以接收来自所述第一重力称重装置的重量信号，并且控制所述控制装置以在流体中填充所述袋中的一个，而另一个袋子被排出流体，反之亦然。本发明还涉及一种用于处理装置的一次性排水管线。

5. 发明申请

WO2015188154A8 SYSTEM FOR CALCULATING A CHANGE IN FLUID VOLUME IN A PUMPING CHAMBER 审中-公开
标题翻译：计算泵送液体流量变化的系统
公开(公告)号：WO2015188154A8
公开(公告)日：2017-01-19
申请号：PCT/US2015034570
申请日：2015-06-05
申请人： DEKA PRODUCTS LP
发明人： NORRIS MICHAEL G , SCARPACI JACOB W , BRYANT ROBERT J , SPENCER GEOFFREY P , GIROUARD PAUL G , KAROL DANIEL S , SINGER DANIEL B , RUSHLOW JOSEPH P , HIBBARD DAVID J , DALE JAMES D , KERWIN JOHN M , COLL ANDREW S , BEAVERS DAVID A , MCGILL DAVID W , HELMORE SIMON C , DOHERTY DAVID B , BOLTON EDGAR J , YOO JINSUN
IPC分类号： A61M1/10 , A61M1/28 , A61M1/30
CPC分类号： A61M39/22 , A61M1/1006 , A61M1/1012 , A61M1/1037 , A61M1/106 , A61M1/1062 , A61M1/1086 , A61M1/1087 , A61M1/1096 , A61M1/166 , A61M1/28 , A61M1/282 , A61M1/288 , A61M2205/12 , A61M2205/3331 , A61M2205/3334 , A61M2205/3379 , A61M2205/3396 , A61M2205/6063
摘要： Improvements in fluid volume measurement systems are disclosed for a pneumatically actuated diaphragm pump in general, and a peritoneal dialysis cycler using a pump cassette in particular. Pump fluid volume measurements are based on pressure measurements in a pump control chamber and a reference chamber in a two-chamber model, with different sections of the apparatus being modeled using a combination of adiabatic, isothermal and polytropic processes. Real time or instantaneous fluid flow measurements in a pump chamber of a diaphragm pump are also disclosed, in this case using a one-chamber ideal gas model and using a high speed processor to obtain and process pump control chamber pressures during fluid flow into or out of the pump chamber. Improved heater control circuitry is also disclosed, to provide added or redundant safety measures, or to reduce current leakage from a heater element during pulse width modulation control of the heater. Improvements are also disclosed in the application of negative pressure during a drain phase in peritoneal dialysis therapy, and to control the amount of intraperitoneal fluid accumulation during a therapy. Improvements in efficiency are also disclosed in the movement of fluid into and out of a two-pump cassette and heater bag of a peritoneal dialysis cycler, and in the synchronization of the operation of two or more pumps in a peritoneal dialysis cycler or other fluid handling devices using a multi-pump arrangement.
摘要翻译：一般来说，对气动驱动的隔膜泵公开了流体体积测量系统的改进，特别是使用泵盒的腹膜透析循环仪。泵流体体积测量基于泵室控制室中的压力测量和双室模型中的参考室，其中该设备的不同部分使用绝热，等温和多变过程的组合进行建模。还公开了在隔膜泵的泵室中的实时或瞬时流体流量测量，在这种情况下使用单室理想气体模型并且使用高速处理器在流体流入或流出期间获得和处理泵控制室压力的泵室。还公开了改进的加热器控制电路，以在加热器的脉冲宽度调制控制期间提供附加的或冗余的安全措施，或减少来自加热器元件的电流泄漏。在腹膜透析治疗期间在排水阶段中施加负压并且在治疗期间控制腹膜内液体积累的量也公开了改进。流体进出腹膜透析循环仪的双泵盒和加热袋，以及在腹膜透析循环仪或其他流体处理中两个或多个泵的操作的同步中也公开了效率的改善使用多泵排列的装置。

6. 发明申请

WO2012172437A3 APPARATUS AND METHOD FOR REAL-TIME MEASUREMENT OF CHANGES IN VOLUME OF BREAST AND OTHER ORGANS 审中-公开
标题翻译：用于实时测量乳腺和其他器官的变化的装置和方法
公开(公告)号：WO2012172437A3
公开(公告)日：2013-05-23
申请号：PCT/IB2012001762
申请日：2012-02-24
申请人： MARDIKS EITAN , NETZER GILY , BLONDHEIM DAVID SIMEON
发明人： MARDIKS EITAN , NETZER GILY , BLONDHEIM DAVID SIMEON
IPC分类号： A61B5/103 , A41C3/04 , A61B5/107 , A61M1/00
CPC分类号： A61B5/1073 , A41C3/04 , A61B5/0053 , A61B5/11 , A61B5/4288 , A61B5/4312 , A61B5/4878 , A61B5/6804 , A61B5/6843 , A61B5/7278 , A61B5/742 , A61B2503/04 , A61M1/062 , A61M2205/3389 , A61M2205/3396
摘要： An apparatus and method for determination of change in volume of a body part or body organ on a real-time basis. In a breastfeeding application, an inflatable cuff is positioned on a nursing breast and allows direct access to the nipple by the breastfeeding infant. The inflatable cuff includes an outer shell portion and an inner inflatable bladder. The pressure in the bladder is monitored regularly by a pressure sensor, during a breastfeeding session. When the pressure drops below a preselected pressure, a controller directs a pump to pump air into the inflatable bladder to maintain the preselected pressure. The volume of added air is monitored during the breastfeeding session. Various calibrations are used to correlate the amount of added air, to the volume of breast milk withdrawn from the breast. The volume of breast milk withdrawn during breastfeeding is calculated and displayed throughout the breastfeeding session.
摘要翻译：一种用于确定身体部位或身体器官体积变化的实时设备和方法。在母乳喂养的应用中，充气袖口位于哺乳乳房上，并允许母乳喂养婴儿直接进入乳头。可充气套包括外壳部分和内部充气囊。在母乳喂养期间，通过压力传感器定期监测膀胱内的压力。当压力低于预选压力时，控制器引导泵将空气泵送到可膨胀的气囊中以保持预选的压力。在母乳喂养期间监测添加的空气量。使用各种校准来将添加的空气量与从乳房抽出的母乳的体积相关联。在母乳喂养期间计算并显示母乳喂养期间抽出的母乳量。

7. 发明申请

WO2012140056A1 INFUSION PUMP DEVICE WITH IMPROVED PRIMING OF THE FLUIDIC SYSTEM AND METHOD FOR PRIMING SUCH AN INFUSION PUMP DEVICE 审中-公开
标题翻译：具有改进的流体系统的引导的输液泵装置和用于引导这种输注泵装置的方法
公开(公告)号：WO2012140056A1
公开(公告)日：2012-10-18
申请号：PCT/EP2012/056543
申请日：2012-04-11
申请人： F. HOFFMANN-LA ROCHE AG , ROCHE DIAGNOSTICS GMBH , GEIPEL, Andreas , DOGWILER, Jörg , HAUETER, Ulrich , SCHEURER, Simon , ZIHLMANN, Rudolf , TEUTSCH, David , KÜHNI, Florian , SCHALTEGGER, Reto
发明人： GEIPEL, Andreas , DOGWILER, Jörg , HAUETER, Ulrich , SCHEURER, Simon , ZIHLMANN, Rudolf , TEUTSCH, David , KÜHNI, Florian , SCHALTEGGER, Reto
IPC分类号： A61M5/142 , A61M5/168 , A61M5/36 , A61M5/315 , A61M5/14
CPC分类号： A61M5/365 , A61M5/14216 , A61M5/16809 , A61M5/31511 , A61M2005/1402 , A61M2005/14208 , A61M2005/14264 , A61M2005/16868 , A61M2205/3306 , A61M2205/3355 , A61M2205/3365 , A61M2205/3396
摘要： An infusion pump device (10) comprises a primary reservoir (11) for liquid medicament, a pump (14, 16) with a secondary reservoir (14) that is able to retrieve liquid medicament from the primary reservoir and to subsequently dosing said liquid medicament from the secondary reservoir in incremental steps, a first upstream conduit ( 24) fluidly connecting the primary reservoir with the pump, a second downstream conduit ( 25, 28) fluidly connected to the pump for transporting the liquid medicament to an infusion site interface (30), a valve (35) for alternatingly connecting the pump to one of the two conduits, and a control unit configured to control the operation of the infusion pump device. For filling the fluidic system (24, 13, 25, 28) of the infusion pump device with liquid medicament prior to infusion operation, the control unit causes the infusion pump device to carry out the following steps: (a) bringing the pump to an initial state where an inner volume (13) of the secondary reservoir is minimal; (b) switching the valve to a first state, in which the secondary reservoir is connected to the first conduit and the primary reservoir; (c) retrieving liquid medicament from the primary reservoir, wherein the retrieved liquid volume (V C ) is at least equal to the inner volume (V B ) of the first upstream conduit; (d) switching the valve to a second state, in which the secondary reservoir is connected to the second downstream conduit; (e) expelling the contents in the secondary reservoir into the second downstream conduit; (f) switching the valve to the first state; (g ) retrieving liquid medicament from the primary reservoir, wherein the retrieved liquid volume (V C ) is at least equal to the inner volume (V D + V E + V F ) of the second downstream conduit; (h) switching the valve to the second state; and (i) expelling the contents in the secondary reservoir into the second downstream conduit by shifting the piston to the initial position.
摘要翻译：输液泵装置（10）包括用于液体药物的主储存器（11），具有辅助储存器（14）的泵（14,16），其能够从主储器回收液体药物，并随后对所述液体药物从次级容器以增量步骤，将流体连接初级容器与泵的第一上游管道（24），流体连接到泵的第二下游管道（25,28），用于将液体药物输送到注射部位接口（30 ），用于将泵交替地连接到两个管道中的一个的阀（35），以及被配置为控制输注泵装置的操作的控制单元。为了在输注操作之前用液体药物填充输液泵装置的流体系统（24,13,25,28），控制单元使输液泵装置执行以下步骤：（a）使泵进入初级状态，其中二级容器的内容积（13）最小; （b）将所述阀切换到第一状态，其中所述次级储存器连接到所述第一管道和所述主储存器; （c）从主贮存器回收液体药物，其中回收的液体体积（VC）至少等于第一上游导管的内部体积（VB）; （d）将所述阀切换到第二状态，其中所述辅助储存器连接到所述第二下游导管; （e）将第二储存器中的内容物排出到第二下游导管中; （f）将阀切换到第一状态; （g）从主储存器回收液体药物，其中回收的液体体积（VC）至少等于第二下游导管的内部体积（VD + VE + VF）; （h）将阀切换到第二状态; 和（i）通过将活塞移动到初始位置将第二储存器中的内容物排出到第二下游导管中。

8. 发明申请

WO2009006490A2 TEMPERATURE COMPENSATION FOR PNEUMATIC PUMPING SYSTEM 审中-公开
标题翻译：气动抽气系统的温度补偿
公开(公告)号：WO2009006490A2
公开(公告)日：2009-01-08
申请号：PCT/US2008/068948
申请日：2008-07-02
申请人： BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE S.A. , HUITT, Bruce , VINCENT, Douglas , HECHT, Gideon
发明人： HUITT, Bruce , VINCENT, Douglas , HECHT, Gideon
IPC分类号： A61M1/28
CPC分类号： A61M1/28 , A61M1/166 , A61M2205/12 , A61M2205/3372 , A61M2205/3396 , G01F15/02 , G06F17/40 , G06F19/00 , G16H20/40
摘要： Temperature compensation is applied to correct for temperature mismatch between a reference chamber and a disposable chamber in a pneumatic pumping system for dialysis fluid for peritoneal dialysis. The mismatch creates an error in the calculation of pumping volume of dialysate fluid. Applying a correction for the temperature mismatch helps to more precisely control the volume of dialysate that is metered to the patient. Also disclosed are ways to keep temperatures constant and to use temperature sensors to accurately measure the temperatures of the chambers. In other aspects, the temperature of the dialysate fluid itself may be measured and used to apply a correction to the volume of fluid that is pumped to the patient.
摘要翻译：应用温度补偿来校正用于腹膜透析的透析液的气动泵送系统中的参考腔室和一次性腔室之间的温度不匹配。不匹配在计算透析液的泵送体积时产生错误。对温度失配应用校正有助于更精确地控制对患者计量的透析液的体积。还公开了保持温度恒定的方法并且使用温度传感器来精确测量腔室的温度。在其他方面，透析液本身的温度可以被测量并用于对泵送到患者的流体体积进行校正。

9. 发明申请

WO00069491A1 METHOD FOR PASSING A MIXTURE OF LIQUID THROUGH HUMAN AND/OR ANIMAL ORGANS OR EXTREMITIES 审中-公开
标题翻译： DEVICE对于流人和/或动物器官或肢体
公开(公告)号：WO00069491A1
公开(公告)日：2000-11-23
申请号：PCT/EP2000/004045
申请日：2000-05-06
IPC分类号： A61M5/168 , A61M1/10 , A61M1/36 , G05D11/00
CPC分类号： G05D11/008 , A61M1/3613 , A61M1/367 , A61M2205/3396
摘要： The invention relates to a device (10) for passing a mixture of liquids, preferably mixtures of blood and pharmaca, through human and/or animal organs or extremities. The inventive device (10) comprises at least one pump device (11) for circulating the liquids and at least one mixing device (14) which is provided with at least two wheels (17, 18) having chambers for mixing the liquids in a dosed manner.
摘要翻译：装置（10），用于人类和/或动物器官或四肢用的液体的混合物，优选与血液和药物的混合物的通道，其具有至少一个泵装置（11）用于循环流体和具有至少一个混合单元（14），其中所述至少一个混合单元（14）包括至少两个腔室的车轮（17，18），用于液体的计量混合。

10. 发明申请

WO2015188154A1 SYSTEM FOR CALCULATING A CHANGE IN FLUID VOLUME IN A PUMPING CHAMBER 审中-公开
标题翻译：计算泵送液体流量变化的系统
公开(公告)号：WO2015188154A1
公开(公告)日：2015-12-10
申请号：PCT/US2015/034570
申请日：2015-06-05
申请人： DEKA PRODUCTS LIMITED PARTNERSHIP
发明人： NORRIS, Michael, G. , SCARPACI, Jacob, W. , BRYANT, Robert, J. , SPENCER, Geoffrey, P. , GIROUARD, Paul, G. , KAROL, Daniel, S. , SINGER, Daniel, B. , RUSHLOW, Joseph, P. , HIBBARD, David, J. , DALE, James, D. , KERWIN, John, M. , COLL, Andrew, S. , BEAVERS, David, A. , MCGILL, David, W. , HELMORE, Simon, C. , DOHERTY, David, A. , BOLTON, Edgar, J. , YOO, Jinsun
IPC分类号： A61M1/10 , A61M1/28 , A61M1/30
CPC分类号： A61M39/22 , A61M1/1006 , A61M1/1012 , A61M1/1037 , A61M1/106 , A61M1/1062 , A61M1/1086 , A61M1/1087 , A61M1/1096 , A61M1/166 , A61M1/28 , A61M1/282 , A61M1/288 , A61M2205/12 , A61M2205/3331 , A61M2205/3334 , A61M2205/3379 , A61M2205/3396 , A61M2205/6063
摘要： Improvements in fluid volume measurement systems are disclosed for a pneumatically actuated diaphragm pump in general, and a peritoneal dialysis cycler using a pump cassette in particular. Pump fluid volume measurements are based on pressure measurements in a pump control chamber and a reference chamber in a two-chamber model, with different sections of the apparatus being modeled using a combination of adiabatic, isothermal and polytropic processes. Real time or instantaneous fluid flow measurements in a pump chamber of a diaphragm pump are also disclosed, in this case using a one-chamber ideal gas model and using a high speed processor to obtain and process pump control chamber pressures during fluid flow into or out of the pump chamber. Improved heater control circuitry is also disclosed, to provide added or redundant safety measures, or to reduce current leakage from a heater element during pulse width modulation control of the heater. Improvements are also disclosed in the application of negative pressure during a drain phase in peritoneal dialysis therapy, and to control the amount of intraperitoneal fluid accumulation during a therapy. Improvements in efficiency are also disclosed in the movement of fluid into and out of a two-pump cassette and heater bag of a peritoneal dialysis cycler, and in the synchronization of the operation of two or more pumps in a peritoneal dialysis cycler or other fluid handling devices using a multi-pump arrangement.
摘要翻译：一般来说，对气动驱动的隔膜泵公开了流体体积测量系统的改进，特别是使用泵盒的腹膜透析循环仪。泵流体体积测量基于泵室控制室中的压力测量和双室模型中的参考室，其中该设备的不同部分使用绝热，等温和多变过程的组合进行建模。还公开了在隔膜泵的泵室中的实时或瞬时流体流量测量，在这种情况下使用单室理想气体模型并且使用高速处理器在流体流入或流出期间获得和处理泵控制室压力的泵室。还公开了改进的加热器控制电路，以在加热器的脉冲宽度调制控制期间提供附加的或冗余的安全措施，或减少来自加热器元件的电流泄漏。在腹膜透析治疗期间在排水阶段中施加负压并且在治疗期间控制腹膜内液体积累的量也公开了改进。流体进出腹膜透析循环仪的双泵盒和加热袋，以及在腹膜透析循环仪或其他流体处理中两个或多个泵的操作的同步中也公开了效率的改善使用多泵排列的装置。

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