专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO9922005B1 HEPARAN SULFATE D-GLUCOSAMINYL 3-O-SULFOTRANSFERASES, AN USES THEREFOR 审中-公开
标题翻译：硫酸乙酰肝素D-葡糖胺3-O-磺酸酯转运酶，用途
公开(公告)号：WO9922005B1
公开(公告)日：1999-11-11
申请号：PCT/US9822597
申请日：1998-10-23
申请人： MASSACHUSETTS INST TECHNOLOGY , ROSENBERG ROBERT D , SHWORAK NICHOLAS W , LIU JIAN , FRITZE LINDA M S , SCHWARTZ JOHN J , ZHANG LIJUAN
发明人： ROSENBERG ROBERT D , SHWORAK NICHOLAS W , LIU JIAN , FRITZE LINDA M S , SCHWARTZ JOHN J , ZHANG LIJUAN
IPC分类号： C12N9/10 , C12N15/54 , A01K67/027 , C07K16/40 , G01N33/68
CPC分类号： C12N9/13 , A01K2217/05 , C07K2319/20
摘要： Disclosed are novel isolated nucleic acids and substancially pure protein preparations for naturally occurring and synthetic or chimeric heparan sulfate D-glucosaminyl 3-O-sulfo-transferases (3-OSTs). Also disclosed are uses for these genes and proteins, including uses for the modification and sequencing of glycosaminoglycans.
摘要翻译：公开了用于天然存在的和合成的或嵌合的硫酸乙酰肝素D-葡糖胺基3-O-磺基转移酶（3-OST）的新型分离的核酸和基本纯的蛋白质制剂。还公开了这些基因和蛋白质的用途，包括用于糖胺聚糖的修饰和测序。

2. 发明申请

WO9922005A3 HEPARAN SULFATE D-GLUCOSAMINYL 3-O-SULFOTRANSFERASES, AN USES THEREFOR 审中-公开
公开(公告)号：WO9922005A3
公开(公告)日：1999-10-07
申请号：PCT/US9822597
申请日：1998-10-23
申请人： MASSACHUSETTS INST TECHNOLOGY , ROSENBERG ROBERT D , SHWORAK NICHOLAS W , LIU JIAN , FRITZE LINDA M S , SCHWARTZ JOHN J , ZHANG LIJUAN
发明人： ROSENBERG ROBERT D , SHWORAK NICHOLAS W , LIU JIAN , FRITZE LINDA M S , SCHWARTZ JOHN J , ZHANG LIJUAN
IPC分类号： C12N9/10 , C12N15/54 , A01K67/027 , C07K16/40 , G01N33/68
CPC分类号： C12N9/13 , A01K2217/05 , C07K2319/20
摘要： Disclosed are novel isolated nucleic acids and substancially pure protein preparations for naturally occurring and synthetic or chimeric heparan sulfate D-glucosaminyl 3-O-sulfo-transferases (3-OSTs). Also disclosed are uses for these genes and proteins, including uses for the modification and sequencing of glycosaminoglycans.

3. 发明申请

WO0223185A3 DEVICES AND METHODS FOR DIRECT ELECTRONIC READOUT OF BIOMOLECULAR INTERACTIONS 审中-公开
标题翻译：用于直接电子读取生物分子相互作用的装置和方法
公开(公告)号：WO0223185A3
公开(公告)日：2004-09-02
申请号：PCT/US0128821
申请日：2001-09-14
申请人： ENGENEOS INC , SCHWARTZ JOHN J , JACOBSON JOSEPH
发明人： SCHWARTZ JOHN J , JACOBSON JOSEPH
IPC分类号： C12Q1/68 , G01N27/02 , G01N27/07 , G01N27/22 , G01N27/403 , B01J19/00 , G01N33/543
CPC分类号： C12Q1/6825 , B01J2219/00274 , C12Q1/6837 , G01N27/3276 , C12Q2565/501
摘要： Disclosed herein are methods and devices for direct electronic readout of biomolecular interactions. The devices of the invention include substrates having a number of electrically conductive sites. The sites are arranged in a spatially-addressable array and are electrically isolated from each other. The devices also include a number of types of probes, each type of probe having a hybridization moiety capable of recognising and hybridizing to a different nucleic acid sequence. Generally, each site is in electrically conductive contact with one type of probe. Similarly, each type of probe is in electrically conductive contact with at least one electrically conductive site. The devices and methods of the invention permit detection of genetic lesions indicative of disease. Also, the devices and methods permit measurement of nucleic acid concentrations useful for predictive medicine as well as therapeutic drug monitoring, for example.
摘要翻译：本文公开了用于直接电子读出生物分子相互作用的方法和装置。本发明的装置包括具有多个导电部位的基板。这些位置被布置在空间可寻址的阵列中并且彼此电隔离。所述装置还包括许多类型的探针，每种类型的探针具有能够识别和与不同核酸序列杂交的杂交部分。通常，每个位置与一种类型的探针导电接触。类似地，每种类型的探针与至少一个导电部位导电接触。本发明的装置和方法允许检测指示疾病的遗传病变。此外，装置和方法允许例如测量可用于预测药物的核酸浓度以及治疗药物监测。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式