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1. 发明申请

WO2014040954A1 MEASUREMENT OF MAGNETIC RESONANCE RHEOLOGY TRANSDUCER VIBRATIONS USING NAVIGATORS 审中-公开
标题翻译：使用导航仪测量磁共振流变传感器振动
公开(公告)号：WO2014040954A1
公开(公告)日：2014-03-20
申请号：PCT/EP2013/068626
申请日：2013-09-09
申请人： KONINKLIJKE PHILIPS N.V. , PHILIPS DEUTSCHLAND GMBH
发明人： VERNICKEL, Peter , WIRTZ, Daniel , LEUSSLER, Christoph , MAZURKEWITZ, Peter
IPC分类号： G01R33/567 , G01R33/563 , G01R33/565
CPC分类号： G01R33/56375 , G01R33/307 , G01R33/3815 , G01R33/385 , G01R33/5608 , G01R33/56358 , G01R33/56509 , G01R33/56563 , G01R33/567 , G01R33/5676
摘要： The invention provides for a medical instrument (200, 400, 500) comprising a magnetic resonance imaging system (202), a transducer (222) for mechanically vibrating at least a portion of the subject within the imaging zone. Instructions cause a processor (236) controlling the medical instrument to: control (100) the transducer to vibrate; control (102) the magnetic resonance imaging system to repeatedly acquire the magnetic resonance data (252) using a first spatially encoding pulse sequence (250); control (104) the magnetic resonance imaging system to acquire navigator data (256) using a second spatially encoding pulse sequence (254); construct (106) a set of navigator profiles (258, 804, 904, 1004, 1108, 1208, 1308) using the navigator data; determine (108) at least one parameter (260) descriptive of transducer vibrations using the set of navigator profiles; and reconstruct (110) at least one magnetic resonance rheology image (262) from the magnetic resonance data.
摘要翻译：本发明提供一种包括磁共振成像系统（202）的医疗器械（200,400,500），用于在成像区内机械地振动受试者的至少一部分的换能器（222）。指令使处理器（236）控制医疗器械：控制（100）换能器振动; 控制（102）所述磁共振成像系统以使用第一空间编码脉冲序列（250）重复获取所述磁共振数据（252）。控制（104）所述磁共振成像系统以使用第二空间编码脉冲序列（254）获取导航器数据（256）; 使用导航器数据构造（106）一组导航器简档（258,804,904,1004,1108,1208,1308）; 使用所述一组导航器轮廓来确定（108）描述换能器振动的至少一个参数（260）; 并从磁共振数据重建（110）至少一个磁共振流变学图像（262）。

2. 发明申请

WO2013186658A2 OSCILLATION APPLICATOR FOR MR RHEOLOGY 审中-公开
标题翻译：振荡器应用于MR流变学
公开(公告)号：WO2013186658A2
公开(公告)日：2013-12-19
申请号：PCT/IB2013/054457
申请日：2013-05-30
申请人： KONINKLIJKE PHILIPS N.V. , PHILIPS DEUTSCHLAND GMBH
发明人： VERNICKEL, Peter , LEUSSLER, Christoph , WIRTZ, Daniel , MAZURKEWITZ, Peter
IPC分类号： G01R33/30 , G01R33/563
CPC分类号： A61B5/6831 , A61B5/6843 , G01R33/3415 , G01R33/50 , G01R33/5608 , G01R33/56358
摘要： The invention relates to the field of magnetic resonance (MR) imaging. It concerns an oscillation applicator for MR rheology. It is an object of the invention to provide an oscillation applicator without restrictions regarding the usability for certain body regions. According to the invention, the oscillation applicator comprises at least one transducer which generates a reciprocating motion at a given frequency and a belt (19) mechanically coupled to the transducer, which belt (19) is designed to be wrapped around a patient's body (10). Moreover, the invention relates to a MR device (1) and to a method of MR imaging.
摘要翻译：本发明涉及磁共振（MR）成像领域。它涉及MR流变学的振荡施加器。本发明的目的是提供一种振荡施加器，而不限制某些身体区域的可用性。根据本发明，振动施加器包括产生给定频率的往复运动的至少一个换能器和机械耦合到换能器的皮带（19），所述皮带（19）被设计成围绕患者身体（10 ）。此外，本发明涉及一种MR装置（1）和一种MR成像方法。

3. 发明申请

WO2014161783A1 REAL-TIME ENERGY DEPOSITING THERAPY SYSTEM CONTROLLED BY MAGNETIC RESONANCE RHEOLOGY 审中-公开
标题翻译：实时能量沉积治疗系统由磁共振流变学控制
公开(公告)号：WO2014161783A1
公开(公告)日：2014-10-09
申请号：PCT/EP2014/056288
申请日：2014-03-28
申请人： KONINKLIJKE PHILIPS N.V. , PHILIPS DEUTSCHLAND GMBH
发明人： LEUSSLER, Christoph , WIRTZ, Daniel , VERNICKEL, Peter , MAZURKEWITZ, Peter
IPC分类号： A61N7/02 , A61B18/18 , A61B19/00 , G01R33/563
CPC分类号： A61B5/4836 , A61B5/055 , A61B18/1815 , A61B90/37 , A61B2018/0019 , A61B2018/00577 , A61B2018/00642 , A61B2018/00898 , A61B2018/00904 , A61B2090/374 , A61N7/02 , A61N2005/1055 , A61N2007/0078 , G01R33/4808 , G01R33/56358
摘要： An energy depositing therapy system (10), comprising: • - an energy depositing unit (12) provided for locally depositing energy into a therapy zone (56) of a subject of interest (28) for therapy purposes; • - a transducer unit (32) that is provided for applying mechanical oscillations to at least a portion of the subject of interest (28); • - a magnetic resonance imaging system (14) provided for acquiring magnetic resonance imaging data from at least the portion of a subject of interest (28), comprising an image processing unit (24) configured to image the mechanical oscillations; • - a control unit (40) that is connectable to the energy depositing unit (12), the transducer unit (32) and a magnetic resonance scanner (16) of the magnetic resonance imaging system (14), wherein • the control unit (40) is configured to control the depositing of energy in dependence of the processed magnetic resonance imaging data of the portion of the subject of interest (28);
摘要翻译：一种能量沉积治疗系统（10），包括： - 能量沉积单元（12），用于局部地将能量放入感兴趣的对象（28）的治疗区（56）中，用于治疗目的; •传感器单元（32），其被提供用于对感兴趣对象（28）的至少一部分施加机械振荡; •磁共振成像系统（14），用于从感兴趣对象的至少一部分获取磁共振成像数据（28），包括被配置成对所述机械振荡进行成像的图像处理单元（24）; •可连接到所述能量沉积单元（12），所述换能器单元（32）和所述磁共振成像系统（14）的磁共振扫描器（16）的控制单元（40），其中所述控制单元 40）被配置为根据感兴趣对象的部分的处理的磁共振成像数据（28）来控制能量的沉积;

4. 发明申请

WO2014072895A1 RHEOLOGY UNIT FOR MRI WITH INTEGRATED OSCILLATOR AND RF ANTENNA 审中-公开
标题翻译：具有集成振荡器和射频天线的MRI的流变学单元
公开(公告)号：WO2014072895A1
公开(公告)日：2014-05-15
申请号：PCT/IB2013/059876
申请日：2013-11-04
申请人： KONINKLIJKE PHILIPS N.V. , PHILIPS DEUTSCHLAND GMBH
发明人： WIRTZ, Daniel , VERNICKEL, Peter , MAZURKEWITZ, Peter , LEUSSLER, Christoph
IPC分类号： G01R33/34 , G01R33/36 , G01R33/563
CPC分类号： G01R33/34084 , A61B5/055 , G01R33/3415 , G01R33/3692 , G01R33/56358
摘要： The present invention provides a rheology module (200) for use in a magnetic resonance (MR) rheology imaging system (110), whereby the rheology module (200) is adapted to introduce mechanical oscillations into a subject of interest(120), comprising a housing(202), a mechanical oscillator unit(204), which extends at least partially outside the housing (202) and is movable relative to the housing(202), and a transducer (206) for moving the oscillator unit(204),whereby the rheology module (200) comprises at least one radio frequency (RF) antenna unit(210, 212), which comprises at least one RF coil(214, 216).With the RF antenna device integrated into the rheology module, an antenna placement close to a region of interest (ROI) can be achieved to improve the MR imaging capabilities of a MR rheology imaging system. Thus, imaging of the ROI can be performed more efficiently. Furthermore, connection and cabling can be facilitated, since only one module has to be connected to generate the oscillation and to operate the RF antenna device.
摘要翻译：本发明提供一种用于磁共振（MR）流变学成像系统（110）的流变学模块（200），由此流变学模块（200）适于将机械振荡引入感兴趣的对象（120），包括壳体（202），机械振荡器单元（204），其至少部分地延伸到壳体（202）外部并且可相对于壳体（202）移动;以及用于移动振荡器单元（204）的换能器（206）由此流变学模块（200）包括至少一个射频（RF）天线单元（210,212），其包括至少一个RF线圈（214,216）。随着RF天线装置集成到流变模块中，天线可以实现靠近感兴趣区域（ROI）的放置以改善MR流变学成像系统的MR成像能力。因此，可以更有效地执行ROI的成像。此外，由于仅必须连接一个模块以产生振荡并操作RF天线装置，所以可以促进连接和布线。

5. 发明申请

WO2014024112A2 ENDORECTAL PROSTATE COIL WITH OPEN ACCESS FOR SURGICAL INSTRUMENTS 审中-公开
标题翻译：手术器械开放的前列腺前列腺线圈
公开(公告)号：WO2014024112A2
公开(公告)日：2014-02-13
申请号：PCT/IB2013/056400
申请日：2013-08-05
申请人： KONINKLIJKE PHILIPS N.V. , PHILIPS DEUTSCHLAND GMBH
发明人： WIRTZ, Daniel , MAZURKEWITZ, Peter , LEUSSLER, Christoph
IPC分类号： G01R33/28
CPC分类号： A61B5/055 , A61B10/02 , A61B17/0218 , A61B18/00 , A61B2018/005 , A61B2018/00577 , A61B2018/00982 , G01R33/285 , G01R33/286 , G01R33/34046 , G01R33/34069 , G01R33/34084
摘要： An endorectal coil (1) includes a tube (40), a spreader (44), and one or more electrically conductive elements (64). The tube (40) is configured for insertion into the rectum (42). The spreader (44) is configured to be positioned at a distal end of the tube (40) and mechanically spread to compress surrounding tissue after the tube (40) is inserted. The one or more electrically conductive elements (64) are tuned to receive magnetic resonance data disposed on at least one of the tube (40), the spreader (44), and adjacent the tube and spreader.
摘要翻译：直肠内线圈（1）包括管（40），扩张器（44）和一个或多个导电元件（64）。管（40）构造成用于插入直肠（42）中。扩张器（44）构造成定位在管（40）的远端处并且在插入管（40）之后机械扩张以压缩周围组织。所述一个或多个导电元件（64）被调谐以接收设置在所述管（40），所述扩张器（44）中的至少一个上并邻近所述管和扩张器的磁共振数据。

6. 发明申请

WO2013182949A1 NON-INVASIVE PROSTATE COIL FOR MR SYSTEMS WITH VERTICAL MAIN FIELD 审中-公开
标题翻译：具有垂直主场的MR系统的非入侵前置线圈
公开(公告)号：WO2013182949A1
公开(公告)日：2013-12-12
申请号：PCT/IB2013/054369
申请日：2013-05-27
申请人： KONINKLIJKE PHILIPS N.V. , PHILIPS DEUTSCHLAND GMBH
发明人： MAZURKEWITZ, Peter , LEUSSLER, Christoph
IPC分类号： G01R33/34
CPC分类号： G01R33/38 , A61B5/055 , A61B5/4381 , G01R33/34 , G01R33/34053 , G01R33/34084 , G01R33/3415 , G01R33/36 , G01R33/3678 , G01R33/3692 , G01R33/3806
摘要： An inductively coupled magnetic resonance local prostate radio frequency coil (10) includes at least two connected electrically conductive loops (50) and an interface device (80). The at least two connected electrically conductive loops (50) are tuned to receive magnetic resonance radio frequency signal components along an axis of a subject disposed in a main magnetic field (B0) orthogonal to the axis of the subject (i.e. an open MRI system having a vertical magnetic field) and generate one or more currents indicative of the received magnetic resonance signal components. The interface device (80) connected to the at least two conductive loops transmits measures of the one or more currents to a signal processing system.
摘要翻译：电感耦合磁共振局部前列腺射频线圈（10）包括至少两个连接的导电回路（50）和接口装置（80）。所述至少两个连接的导电环路（50）被调谐以沿着设置在与被摄体的轴线正交的主磁场（B0）中的对象的轴接收磁共振射频信号分量（即，具有垂直磁场）并产生指示所接收的磁共振信号分量的一个或多个电流。连接到至少两个导电回路的接口装置（80）将一个或多个电流的测量值传送到信号处理系统。

7. 发明申请

WO2017157880A1 ELECTROMAGNETIC DRIVABLE INSERTS 审中-公开
标题翻译：电磁驱动器
公开(公告)号：WO2017157880A1
公开(公告)日：2017-09-21
申请号：PCT/EP2017/055896
申请日：2017-03-14
申请人： KONINKLIJKE PHILIPS N.V.
发明人： GLEICH, Bernhard , SCHMALE, Ingo , STEHNING, Christian , RAHMER, Jürgen Erwin , MAZURKEWITZ, Peter , BONTUS, Claas , WIRTZ, Daniel , BORGERT, Jörn
IPC分类号： A61B17/00 , A61N5/10
CPC分类号： A61N5/1001 , A61B17/861 , A61B17/8685 , A61B17/8875 , A61B2017/00411 , A61N2005/1024 , A61N2005/109 , A61N2005/1094
摘要： The present invention relates to magnetically activatable inserts. In order to provide improved activation of inserted implants, a drive threaded joint (1) for insertion in a body structure is provided. The drive threaded joint comprises a first part (2) provided as a thread-body for connection with a support structure, and a second part (3) provided as a drive-body for driving the first part. The thread-body has a thread (4) defining a screwing direction along a thread axis (6). The second part is mechanically connectable to the first part. The second part has a magnetic structure (7) such that a rotating movement of the second part around an axis is activatable by an appropriate magnetic field. The drive threaded joint is further arranged such that a torque energy created by said rotation of the second part is transferrable to the thread-body once the second part is rotationally mechanically connected to the first part, implying thus the driving of the thread-body.
摘要翻译：本发明涉及可磁性激活的插入件。为了提供对插入的植入物的改进的激活，提供了用于插入身体结构中的驱动螺纹接头（1）。驱动螺纹接头包括作为用于与支撑结构连接的螺纹体的第一部分（2）和作为驱动第一部分的驱动体而设置的第二部分（3）。该线主体具有限定沿着螺纹轴线（6）的螺纹方向的螺纹（4）。第二部分机械连接到第一部分。第二部分具有磁结构（7），使得第二部分围绕轴线的旋转运动可通过适当的磁场激活。驱动螺纹接头进一步布置成使得一旦第二部分旋转地机械地连接到第一部分，由第二部分的所述旋转产生的扭矩能量就可传递到螺纹体，这意味着驱动螺纹体。

8. 发明申请

WO2016120086A1 AUTOMATED SCAN PLANNING FOR FOLLOW-UP MAGNETIC RESONANCE IMAGING 审中-公开
标题翻译：自动扫描计划，用于以下磁共振成像
公开(公告)号：WO2016120086A1
公开(公告)日：2016-08-04
申请号：PCT/EP2016/050705
申请日：2016-01-15
申请人： KONINKLIJKE PHILIPS N.V.
发明人： MAZURKEWITZ, Peter , SENEGAS, Julien , BYSTROV, Daniel
IPC分类号： G01R33/54 , G01R33/565 , G06T7/00
CPC分类号： G06T3/0068 , G01R33/543 , G01R33/56509 , G06T7/0016 , G06T7/30 , G06T7/74 , G06T11/008 , G06T15/08 , G06T2207/10088 , G06T2211/40 , G06T2215/16
摘要： The invention provides for a mri system (100) for acquiring magnetic resonance data (158, 168) from a subject. The execution of machine- executable instructions (180, 182, 184, 186, 188) causes a processor (144) to: receive (300) a baseline medical image (152) data descriptive of one or more internal structures (126) of the subject; receive (302) a baseline scan geometry (154); acquire (304) survey magnetic resonance data (158) from the subject by controlling the magnetic resonance imaging system with survey pulse sequence data, wherein the survey pulse sequence data comprises instructions for controlling the magnetic resonance imaging system to acquire magnetic resonance data descriptive of a three-dimensional volume (124) of the subject; reconstruct (306) the survey magnetic resonance data into a three-dimensional survey image (160); calculate (308) location data by processing the three dimensional survey image with an organ detection algorithm (182), wherein the location data is descriptive of a target region (128); assign (310) a predefined region of interest (130) to the three dimensional survey image using the location data; calculate (312) registration data (164) by registering the baseline medical image to the three dimensional survey image.
摘要翻译：本发明提供一种用于从对象获取磁共振数据（158,168）的系统（100）。机器可执行指令（180,182,184,188,188）的执行使得处理器（144）：接收（300）描述一个或多个内部结构（126）的基线医学图像（152）数据学科; 接收（302）基线扫描几何（154）; 通过用测量脉冲序列数据控制磁共振成像系统来获取（304）调查磁共振数据（158），其中测量脉冲序列数据包括用于控制磁共振成像系统以获取描述a 受试者的三维体积（124）将调查磁共振数据重建（306）成三维测量图像（160）; 通过用器官检测算法（182）处理三维测量图像来计算（308）位置数据，其中所述位置数据描述目标区域（128）; 使用所述位置数据将预定义感兴趣区域（310）分配（310）到所述三维测绘图像; 通过将基线医学图像登记到三维测量图像来计算（312）注册数据（164）。

9. 发明申请

WO2015144811A1 RHEOLOGY SYSTEM AND MR RHEOLOGY SYSTEM WITH RHEOLOGY SENSOR FEEDBACK CONTROL 审中-公开
标题翻译：流变学系统与流变学流变学系统与传感器反馈控制
公开(公告)号：WO2015144811A1
公开(公告)日：2015-10-01
申请号：PCT/EP2015/056526
申请日：2015-03-26
申请人： KONINKLIJKE PHILIPS N.V.
发明人： WIRTZ, Daniel , LEUSSLER, Christoph , MAZURKEWITZ, Peter
IPC分类号： G01R33/563 , A61B5/00
CPC分类号： A61B5/055 , A61B5/0051 , G01R33/30 , G01R33/56358
摘要： The present invention provides a rheology system (202) comprising a rheology transducer device (204) for introducing mechanical waves into a subject of interest (120), whereby the rheology transducer device (204) comprises multiple transducers (212), a driving device (206) for driving the rheology transducer device (204), a sensor device (208) for sensing mechanical waves at the subject of interest (120), and a control device (210) for receiving input from the sensor device (208) and for controlling the driving device (206) based on the received input from the sensor device (208). The present invention further provides a MR rheology system (200) comprising a MR imaging system (110), and the above rheology system (202), whereby the MR imaging system (110) is adapted to control the rheology system (200). Still further, the present invention provides a rheology method comprising the steps of providing a rheology system (202) with its rheology transducer device (204) and its sensor device (208) in contact to a subject of interest (120), driving the rheology transducer device (204) to introduce mechanical waves into the subject of interest (120), sensing mechanical waves at the subject of interest (120) using the sensor device (208), and performing feedback control for driving the rheology transducer device (204) based on the mechanical waves sensed using the sensor device (208). The invention also provides MR rheology method based on the above rheology method with and without real-time feedback control.
摘要翻译：本发明提供一种流变系统（202），其包括用于将机械波引入感兴趣的对象（120）的流变学换能器装置（204），由此流变学换能器装置（204）包括多个换能器（212），驱动装置 206），用于驱动所述流变换能器装置（204）的传感器装置（208），用于感测感兴趣对象（120）的机械波的传感器装置（208）和用于接收来自传感器装置（208）的输入的控制装置基于从所述传感器装置（208）接收到的输入来控制所述驱动装置（206）。本发明还提供了一种MR流变系统（200），其包括MR成像系统（110）和上述流变系统（202），由此MR成像系统（110）适于控制流变系统（200）。此外，本发明提供一种流变学方法，其包括以下步骤：提供其流变学系统（202）与其流变学换能器装置（204）及其传感器装置（208）接触感兴趣的对象（120），驱动流变学传感器装置（204），以将机械波引入感兴趣的对象（120）中，使用传感器装置（208）感测感兴趣对象（120）上的机械波，以及执行用于驱动流变换能器装置（204）的反馈控制，基于使用传感器装置（208）感测的机械波。本发明还提供了基于上述具有和不具有实时反馈控制的流变学方法的MR流变学方法。

10. 发明申请

WO2019238462A1 POSITION FEED BACK INDICATOR FOR MEDICAL IMAGING 审中-公开
公开(公告)号：WO2019238462A1
公开(公告)日：2019-12-19
申请号：PCT/EP2019/064404
申请日：2019-06-04
申请人： KONINKLIJKE PHILIPS N.V.
发明人： KRUEGER, Sascha , STEHNING, Christian , MAZURKEWITZ, Peter
IPC分类号： A61B6/00 , A61B5/11 , G06T7/20 , G06T7/30 , A61B5/055 , G01R33/48
摘要： The invention provides for a medical instrument (100, 300, 400, 500, 600) comprising a camera system (102, 102', 102'') for imaging a portion (418) of a subject (108) reposing on a subject support (106). The medical instrument further comprises a display system (104) for rendering a position feedback indicator (130, 900). The display system is configured such that the position feedback indicator is visible to the subject when the subject is reposing on the subject support. The execution of the machine executable instructions (120) causes a processor (114) controlling the medical instrument to: acquire (200) a base position image (122) using the camera system; repeatedly (202) acquire a subsequent image (124) using the camera system; repeatedly (204) calculate an image transformation (126) from voxels of at least a portion of the base position image to voxels of the subsequent image by inputting the base position image and the subsequent image into an image transformation algorithm (128); and repeatedly (206) render a position feedback indicator (130, 900) on the display, wherein the position feedback indicator is controlled by the image transformation.

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