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1. 发明申请

WO2009063390A1 METHOD OF AUTOMATICALLY CORRECTING MIS-ORIENTATION OF MEDICAL IMAGES 审中-公开
标题翻译：自动校正医学影像的方法
公开(公告)号：WO2009063390A1
公开(公告)日：2009-05-22
申请号：PCT/IB2008/054699
申请日：2008-11-10
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , WIEMKER, Rafael , BUELOW, Thomas, B. , BARSCHDORF, Hans , MEETZ, Kirsten , SCHULZ, Heinrich, S.
发明人： WIEMKER, Rafael , BUELOW, Thomas, B. , BARSCHDORF, Hans , MEETZ, Kirsten , SCHULZ, Heinrich, S.
IPC分类号： G06T3/00
CPC分类号： G06T3/0068
摘要： This invention relates to a method and image processing apparatus for automatically correcting mis-orientation of medical images. One or more image processing software modules are used to extract (101) anatomical areas from the medical images. It is determined (103) whether the extracted anatomical areas correspond to reference anatomical areas, but the reference anatomical areas have associated thereto data indicating the orientation of the reference anatomical areas. If the extracted anatomical areas correspond with the reference anatomical areas, the true orientation of the extracted anatomical areas is determined (105) by realigning the medical image until the orientation of the extracted anatomical areas corresponds to the orientation of the reference anatomical areas.
摘要翻译：本发明涉及一种用于自动校正医学图像的错误取向的方法和图像处理装置。使用一个或多个图像处理软件模块从医学图像中提取（101）解剖区域。确定（103）所提取的解剖区域是否对应于参考解剖区域，但是参考解剖区域与其相关联地指示参考解剖区域的取向的数据。如果提取的解剖区域与参考解剖区域相对应，则通过重新对准医学图像来确定提取的解剖区域的真实取向（105），直到提取的解剖区域的取向对应于参考解剖区域的取向。

2. 发明申请

WO2009101560A2 APPARATUS FOR SEGMENTING AN OBJECT COMPRISING SUB-OBJECTS 审中-公开
标题翻译：用于分配包含子对象的对象的设备
公开(公告)号：WO2009101560A2
公开(公告)日：2009-08-20
申请号：PCT/IB2009/050495
申请日：2009-02-06
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BLAFFERT, Thomas , BARSCHDORF, Hans , VON BERG, Jens , DRIES, Sebastian, P., M. , LORENZ, Cristian , WIEMKER, Rafael , KLINDER, Tobias , FRANZ, Astrid, R. , RENISCH, Steffen
发明人： BLAFFERT, Thomas , BARSCHDORF, Hans , VON BERG, Jens , DRIES, Sebastian, P., M. , LORENZ, Cristian , WIEMKER, Rafael , KLINDER, Tobias , FRANZ, Astrid, R. , RENISCH, Steffen
IPC分类号： G06T7/00 , A61B5/00
CPC分类号： G06T5/003 , G06T7/11 , G06T7/149 , G06T2207/10081 , G06T2207/20041 , G06T2207/20081 , G06T2207/20124 , G06T2207/20192 , G06T2207/30061
摘要： The present invention relates to an apparatus (1) for segmenting an object comprising sub-objects shown in an object image. The apparatus comprises a feature image generation unit (2) for generating a feature image showing features related to intermediate regions between the sub-objects and a segmentation unit (3) for segmenting the sub-objects by using the object image and the feature image. Preferentially, the feature image generation unit (2) is adapted for generating a feature image from the object image. In a further embodiment, the feature image generation unit (2) comprises a feature enhancing unit for enhancing features related to intermediate regions between the sub-objects in the object image.
摘要翻译：本发明涉及一种用于分割包含物体图像中所示的子对象的物体的装置（1）。该装置包括：特征图像生成单元，用于生成显示与子对象之间的中间区域相关的特征的特征图像和用于通过使用对象图像和特征图像来分割子对象的分割单元（3）。优选地，特征图像生成单元（2）适于从对象图像生成特征图像。在另一实施例中，特征图像生成单元（2）包括特征增强单元，用于增强与对象图像中的子对象之间的中间区域相关的特征。

3. 发明申请

WO2004052206A1 METHOD OF TOMOGRAPHIC IMAGING 审中-公开
标题翻译：图像成像方法
公开(公告)号：WO2004052206A1
公开(公告)日：2004-06-24
申请号：PCT/IB2003/005741
申请日：2003-12-04
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N.V. , NETSCH, Thomas , BARSCHDORF, Hans
发明人： NETSCH, Thomas , BARSCHDORF, Hans
IPC分类号： A61B6/08
CPC分类号： A61B6/08
摘要： The invention relates to a method of tomographic imaging, and in particular a CT or MR method, for the repetitive production of diagnostic slice images of a part of a patient's body. To allow a geometrical transformation (2) to be determined, current reference slice images (1) of the part of the body, which are brought into agreement with earlier reference slice images (3) of the part of the body are first made in this case. Current imaging parameters (5) are then calculated for a current diagnostic slice image (6) by transforming earlier imaging parameters by the geometrical transformation (2) previously determined. To give greater accuracy and, at the same time, a short image-making time, the image proposes that at least two current reference slice images (1, 1') be made, whose image planes are preset in such a way that their relative positions and orientations in three dimensions agree with the relative positions and orientations in three dimensions of the earlier reference slice images (3, 3'), the geometrical transformation (2) being determined in such a way that it brings all the current reference slice images (1, 1') in agreement with the corresponding earlier reference slice images (3, 3') simultaneously.
摘要翻译：本发明涉及用于重复生产患者身体的一部分的诊断切片图像的断层成像方法，特别是CT或MR方法。为了允许确定几何变换（2），首先在身体的一部分与先前的参考切片图像（3）一致的身体部分的当前参考切片图像（1）案件。然后通过先前确定的几何变换（2）将较早的成像参数进行变换，计算当前诊断切片图像（6）的当前成像参数（5）。为了提供更高的准确度，并且同时缩短了图像制作时间，图像提出了至少两个当前的参考切片图像（1,1'），其图像平面被预设为使得它们的相对三维中的位置和取向与早期参考切片图像（3,3'）的三维的相对位置和取向一致，几何变换（2）被确定为使得所有当前参考切片图像（1,1'）与相应的早期参考切片图像（3,3'）同时地一致。

4. 发明申请

WO2010086776A1 SYSTEM FOR PROVIDING LUNG VENTILATION INFORMATION 审中-公开
标题翻译：提供肺通气信息的系统
公开(公告)号：WO2010086776A1
公开(公告)日：2010-08-05
申请号：PCT/IB2010/050305
申请日：2010-01-25
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KABUS, Sven , OPFER, Roland , CARLSEN, Ingwer, C. , RENISCH, Steffen , SABCZYNSKI, Joerg , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , KLINDER, Tobias , LORENZ, Cristian , SCHADEWALDT, Nicole
发明人： KABUS, Sven , OPFER, Roland , CARLSEN, Ingwer, C. , RENISCH, Steffen , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , KLINDER, Tobias , LORENZ, Cristian , SCHADEWALDT, Nicole
IPC分类号： A61B5/08 , A61B6/03 , G06T7/00
CPC分类号： A61B6/5235 , A61B5/08 , A61B6/541 , G06T7/33 , G06T2207/10081 , G06T2207/30061
摘要： A system for displaying lung ventilation information, the system comprising an input (12) and a processing unit (15). The input being provided for receiving multiple CT images (71) of a lung, each CT image (71) corresponding to one phase of at least two different phases in a respiratory cycle. The processing unit (15) being configured to compare CT images (71) corresponding to different phases in the respiratory cycle for determining a deformation vector field for each phase, to generate for each phase a ventilation image (72) based on the corresponding deformation vector field, to spatially align the ventilation images (72), and to generate for at least one common position (62) in each one of the aligned ventilation images (72), a function (81) of a time course of a ventilation value for said common position (62), each ventilation value in the function (81) being based on the deformation vector fields corresponding to the aligned ventilation images (73).
摘要翻译：一种用于显示肺通气信息的系统，所述系统包括输入（12）和处理单元（15）。所述输入被提供用于接收肺的多个CT图像（71），每个CT图像（71）对应于呼吸周期中的至少两个不同相的一个相。所述处理单元（15）被配置为比较对应于呼吸周期中的不同相位的CT图像（71），以确定每个相位的变形矢量场，以根据相应的变形矢量为每个阶段生成通气图像（72）在空间上对准通气图像（72），并且为每个对齐的通气图像（72）中的至少一个公共位置（62）产生功能（81），其中通风值的时间过程为所述公共位置（62）中，所述功能（81）中的每个换气值基于对应于对齐的通气图像（73）的变形矢量场。

5. 发明申请

WO2008065590A1 IMPROVED SEGMENTATION 审中-公开
标题翻译：改进分类
公开(公告)号：WO2008065590A1
公开(公告)日：2008-06-05
申请号：PCT/IB2007/054751
申请日：2007-11-22
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , LORENZ, Cristian , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , DRIES, Sebastian, P., M , KABUS, Sven
发明人： LORENZ, Cristian , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , DRIES, Sebastian, P., M , KABUS, Sven
IPC分类号： G06T5/00
CPC分类号： G06T7/149 , G06T7/11 , G06T2207/10072 , G06T2207/30048
摘要： A computer program product is described to adapt a shape model to a patient data set, the data set representing at least a region of anatomy of the patient, and in which the shape model is pre-adapted to a data set representing substantially the same anatomy of the same patient. This provides a surprisingly better segmentation of the data in the data set. In addition, A computer program product is described for the comparison of quantitative patient data and arranged to access quantitative patient data contained in a patient data record, characterized in that the quantitative patient data is in the form of an adapted shape model, adapted from a pre-adapted shape model. This extends the improvement derived by use of pre-adapted shape models and extends them to the use of pre-adapted shape models for data comparison.
摘要翻译：描述了计算机程序产品以将形状模型适应于患者数据集，所述数据集表示至少一个患者的解剖结构的区域，并且其中形状模型预先适应于表示基本上相同的解剖结构的数据集的同一病人。这为数据集中的数据提供了令人惊奇的更好的分割。另外，计算机程序产品被描述为用于比较定量患者数据并被安排用于访问包含在患者数据记录中的定量患者数据，其特征在于定量患者数据是适应形状模型的形式，预适应形状模型。这扩展了通过使用预先调整的形状模型得到的改进，并将其扩展到使用预先调整的形状模型进行数据比较。

6. 发明申请

WO2012035488A1 CHOOSING ANATOMICAL VARIANT MODEL FOR IMAGE SEGMENTATION 审中-公开
标题翻译：选择用于图像分割的解剖学变体模型
公开(公告)号：WO2012035488A1
公开(公告)日：2012-03-22
申请号：PCT/IB2011/053991
申请日：2011-09-13
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , LORENZ, Cristian , BARSCHDORF, Hans , KLINDER, Tobias , HANNA, Raghed
发明人： LORENZ, Cristian , BARSCHDORF, Hans , KLINDER, Tobias , HANNA, Raghed
IPC分类号： G06T7/00
CPC分类号： G06T7/0012 , G06T7/12 , G06T7/149 , G06T15/08 , G06T17/00 , G06T2207/30004
摘要： The invention relates to a system (100) for segmenting an object in an image, comprising a first adapter (110) for adapting a first model for segmenting the object to the image, an analyzer (115) for extracting a feature from the image based on the adapted first model, a selector (120) for selecting a second model for segmenting the object from a plurality of models for segmenting the object, based on the feature extracted from the image, wherein the second model comprises additional detail of the object, an initializer (125) for initializing the second model based on the adapted first model and/or the feature extracted from the image, and a second adapter (130) for adapting the initialized second model to the image. The features extracted from the image based on the adapted first model help the system (100) to select the second model for segmenting the object from a plurality of models for segmenting the object. The adapted first model and/or the extracted features are also used for initializing the second model. Because the second model comprises the additional detail of the object, the segmentation result using the second model is more complete than the segmentation result obtained using the first model. Moreover, the initialization of the second model based on the adapted first model and/or the detected features improves the accuracy of the second model adaptation.
摘要翻译：本发明涉及一种用于分割图像中的对象的系统（100），包括用于适配用于将对象分割成图像的第一模型的第一适配器（110），用于从图像中提取特征的分析器（115）在适配的第一模型上，基于从图像提取的特征，选择器（120），用于从多个模型中选择用于分割对象的第二模型，用于分割对象，其中第二模型包括对象的附加细节，用于基于所述适配的第一模型和/或从所述图像提取的特征来初始化所述第二模型的初始化器（125）和用于将所述初始化的第二模型适配到所述图像的第二适配器（130）。基于适配的第一模型从图像提取的特征帮助系统（100）选择用于从多个模型分割对象的第二模型以分割对象。适应的第一模型和/或提取的特征也用于初始化第二模型。因为第二模型包括对象的附加细节，所以使用第二模型的分割结果比使用第一模型获得的分割结果更完整。此外，基于适应的第一模型和/或检测到的特征的第二模型的初始化提高了第二模型适应的准确性。

7. 发明申请

WO2008065585A3 IMPROVED PATIENT DATA RECORD AND USER INTERFACE 审中-公开
公开(公告)号：WO2008065585A3
公开(公告)日：2008-06-05
申请号：PCT/IB2007/054740
申请日：2007-11-22
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , LORENZ, Cristian , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , DRIES, Sebastian, P., M. , KABUS, Sven
发明人： LORENZ, Cristian , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , DRIES, Sebastian, P., M. , KABUS, Sven
IPC分类号： G06F19/00
摘要： A patient data record is described comprising a mean model representative of the patient and further comprises at least one shape model to represent data concerning the patient, in which the said mean model comprises at least one region and the said shape model comprises at least one sub-section, and in which the at least one sub-section of the shape model is linked to the equivalent region of the mean model. This has the advantage of allowing greater structure to the patient record. Further a system is described to present patient data upon queries generated by a user and arranged to access the claimed patient data record, and which is further arranged to provide access to information in the sub-section of the shape model when a query generated by the user accesses the equivalent region of the mean model. This system allows full use of the improved patient data record.

8. 发明申请

WO2008026141A2 REDUCTION OF HEART MOTION ARTIFACTS IN THORACIC CT IMAGING 审中-公开
标题翻译：减少心脏CT成像中心脏运动的影响
公开(公告)号：WO2008026141A2
公开(公告)日：2008-03-06
申请号：PCT/IB2007/053403
申请日：2007-08-27
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BARSCHDORF, Hans , VON BERG, Jens , KUHN, Michael, H. , LORENZ, Cristian , BLAFFERT, Thomas
发明人： BARSCHDORF, Hans , VON BERG, Jens , KUHN, Michael, H. , LORENZ, Cristian , BLAFFERT, Thomas
IPC分类号： G06T7/20 , A61B5/00
CPC分类号： G06T7/251 , G06T7/149 , G06T7/33 , G06T2200/04 , G06T2207/10081 , G06T2207/30048 , G06T2207/30061 , G06T2211/412
摘要： The invention relates to a system (100) for adapting a plurality of model meshes to a plurality of image data, the system comprising a registration unit (110) for registering the plurality of model meshes with the plurality of image data on the basis of a computation of a registration transformation for transforming the plurality of model meshes, and an adaptation unit (120) for adapting the plurality of registered model meshes to the plurality of image data on the basis of a computation of locations of mesh vertices of the plurality of model meshes. The system (100) may further comprise a computing unit (130) for computing sparse vector fields comprising vectors of displacements of vertices of the adapted model meshes, an approximation unit (140) for computing dense vector fields on the basis of the sparse vector fields, a merge unit (150) for merging image data sets by means of the computed dense vector fields, and a reconstruction unit (155) for reconstructing a motion-compensated image data from the computed dense vector fields. The described system (100) is capable of reducing motion artifacts in tomographic images computed from data acquired at a plurality of different cardiac cycle phases.
摘要翻译：本发明涉及一种用于将多个模型网格适配到多个图像数据的系统（100），该系统包括登记单元（110），用于基于多个图像数据向多个图像数据登记多个模型网格用于变换多个模型网格的注册变换的计算;以及适应单元，用于根据多个模型的网格顶点的位置的计算来将多个注册模型网格适配到多个图像数据网格。系统（100）还可以包括计算单元（130），用于计算包括适应模型网格的顶点位移矢量的稀疏矢量场，用于基于稀疏矢量场计算密集矢量场的近似单元（140），用于通过所计算的密集矢量场合并图像数据组的合并单元（150），以及用于从所计算的密集矢量场重构运动补偿图像数据的重建单元（155）。所描述的系统（100）能够减少从在多个不同的心动周期阶段获取的数据计算的断层图像中的运动伪影。

9. 发明申请

WO2005083406A1 DEVICE AND METHOD FOR MAPPING THE DISTRIBUTION OF AN X-RAY FLUORESCENCE MARKER 审中-公开
标题翻译：用于映射X射线荧光标记分布的装置和方法
公开(公告)号：WO2005083406A1
公开(公告)日：2005-09-09
申请号：PCT/IB2005/050535
申请日：2005-02-11
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , HARDING, Geoffrey , MARTENS, Gerhard , BARSCHDORF, Hans , SCHWEIZER, Bernd
发明人： HARDING, Geoffrey , MARTENS, Gerhard , BARSCHDORF, Hans , SCHWEIZER, Bernd
IPC分类号： G01N23/223
CPC分类号： G01N23/223 , G01N2223/076 , G01N2223/0766
摘要： The invention relates to a method and a device for determining the distribution of an X-ray fluorescence (XRF) marker (16) in a body volume (14). The body volume (14) is irradiated with a beam of rays (12) from an X-ray source (10) with a first ray component with a quantum energy just above and a second ray component with a quantum energy just below the K-edge of the XRF marker (16). Secondary radiation emitted from the body volume (14) is detected in a location-resolved way by a detector (30). To separate the X-ray fluorescence components in the secondary radiation from background radiation, the body volume is irradiated for a second time with a beam of rays from which the first ray component has been substantially removed by a filter (22) made from the material of the XRF marker.
摘要翻译：本发明涉及一种用于确定身体体积（14）中的X射线荧光（XRF）标记物（16）的分布的方法和装置。用来自X射线源（10）的射线束（12）照射具有刚好在上面的量子能的第一射线分量的体积（14），并且具有刚好低于K值的量子能量的第二射线分量，边缘的XRF标记（16）。通过检测器（30）以位置分辨的方式检测从体积（14）发射的次级辐射。为了将二次辐射中的X射线荧光成分从背景辐射中分离出来，用第一射线成分基本上被该材料制成的过滤器（22）除去的射线束照射体积第二次的XRF标记。

10. 发明申请

WO2006038191A2 X-RAY SOURCE APPARATUS, COMPUTER TOMOGRAPHY APPARATUS, AND METHOD OF OPERATING AN X-RAY SOURCE APPARATUS 审中-公开
标题翻译： X射线源装置，计算机摄影装置和操作X射线源装置的方法
公开(公告)号：WO2006038191A2
公开(公告)日：2006-04-13
申请号：PCT/IB2005/053272
申请日：2005-10-05
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , BARSCHDORF, Hans , SCHLOMKA, Jens-Peter
发明人： BARSCHDORF, Hans , SCHLOMKA, Jens-Peter
IPC分类号： G01N23/04 , H01J35/14 , H01J35/30
CPC分类号： H01J35/14 , G01N23/046 , G01N2223/419 , H01J35/30
摘要： An X-ray source apparatus (100) comprises a cathode (101), comprises an electron beam deflection means including one or more electron beam deflection elements (103) and comprises an anode (102). The cathode (101) is adapted to emit an electron beam (104) towards the electron beam deflection means. The electron beam deflection means is adapted to deflect an electron beam (104) coming from the cathode (101) to a selectable part (110) of the anode (102), wherein the selectable part (110) of the anode (102) is selectable to by activating a single one of the one or more electron beam deflection elements (103), with the single activated electron beam deflection element (103) being arranged at a variable position along a propagation path of the electron beam (104) coming from the cathode, (101) such that the electron beam (104) is deflected to the selectable part (110) of the anode (102). The anode (102) is adapted to generate an X-ray beam (104) when being irradiated by an electron beam (104) deflected by the electron beam deflection means.
摘要翻译： X射线源装置（100）包括阴极（101），包括包括一个或多个电子束偏转元件（103）并包括阳极（102）的电子束偏转装置。阴极（101）适于向电子束偏转装置发射电子束（104）。电子束偏转装置适于将来自阴极（101）的电子束（104）偏转到阳极（102）的可选择部分（110），其中阳极（102）的可选择部分（110）是可选择地通过激活一个或多个电子束偏转元件（103）中的单个电子束偏转元件（103），单个激活的电子束偏转元件（103）被布置在沿着电子束（104）的传播路径的可变位置阴极，（101）使得电子束（104）偏转到阳极（102）的可选择部分（110）。当由电子束偏转装置偏转的电子束（104）照射时，阳极（102）适于产生X射线束（104）。

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