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1. 发明申请

WO2011114146A1 METHOD FOR DETECTION OF INFLAMMATION IN THE URINARY TRACT OR URETHRA 审中-公开
标题翻译：用于检测URINHER或URETHRA中的炎症的方法
公开(公告)号：WO2011114146A1
公开(公告)日：2011-09-22
申请号：PCT/GB2011/050512
申请日：2011-03-15
申请人： KNIGHT SCIENTIFIC LIMITED , KNIGHT, Jan , KNIGHT, Robert
发明人： KNIGHT, Jan , KNIGHT, Robert
IPC分类号： G01N33/50 , G01N33/571
CPC分类号： C12Q1/04 , C12Q1/26 , G01N33/56972 , G01N33/571 , G01N33/582 , G01N2333/22 , G01N2333/295
摘要： A method for detecting inflammation in the urinary tract or urethra of a patient, especially urethritis, comprises a) contacting leucocytes obtained from a urine sample provided by the patient with a luminescence reagent which emits light on reaction with an oxidant; b) adding an activator to the mixture of leucocytes and luminescence reagent; c) continuously monitoring and/or measuring light emitted by the luminescence reagent over a predetermined time period commencing before and ending after the addition of the activator. The light emission is indicative of the presence or absence of inflammation in the urinary tract or urethra of the patient. The urine sample is preferably a sample of first pass urine. The method makes possible a diagnosis especially of urethritis and, in particular, urethral infections selected from Chlamydia trachomatis and Neisseria gonorrhoeae , which can be carried out quickly without invasive procedures. A diagnostic kit for carrying out the method, comprising a luminescence reagent which emits light on reaction with an oxidant, an activator and a library of standard signature light emission curves is also disclosed.
摘要翻译：一种用于检测患者尿道或尿道中尤其是尿道炎的炎症的方法，包括：a）将由患者提供的尿液样本获得的白细胞与发出与氧化剂反应的光的发光试剂接触; b）向白细胞和发光试剂混合物中加入活化剂; c）在从活化剂添加之前和之后开始的预定时间段内连续地监测和/或测量由发光试剂发射的光。发光指示患者的尿道或尿道中存在或不存在炎症。尿液样品优选为第一次尿样品。该方法可以特别诊断尿道炎，特别是选自沙眼衣原体和淋病奈瑟氏球菌的尿道感染，可以在没有侵入性手术的情况下快速进行。还公开了一种用于执行该方法的诊断试剂盒，其包括与氧化剂反应发光的发光试剂，活化剂和标准标记光发射曲线库。

2. 发明申请

WO2010058210A1 DEVICE FOR COLLECTING FIRST PASS URINE 审中-公开
标题翻译：用于收集一次尿液的装置
公开(公告)号：WO2010058210A1
公开(公告)日：2010-05-27
申请号：PCT/GB2009/051561
申请日：2009-11-18
申请人： KNIGHT SCIENTIFIC LIMITED , KNIGHT, Jan , KNIGHT, Robert
发明人： KNIGHT, Jan , KNIGHT, Robert
IPC分类号： A61B10/00
CPC分类号： A61B10/007
摘要： A device for collecting a sample of the first pass portion of urine voided by a donor isolated from the midstream portion of the urine comprises a first part (1) comprising an opening at its upper end (4)adapted to receive urine voided by a donor, a urine collection body (3) downstream of the upper end and a closable exit (6) located downstream of the urine collection body and at the lower end (5) of the first part, the exit providing a circular orifice (7), a second part (2) located downstream of the exit of the first part and comprising a collecting vessel(10) which is in communication with the exit of the first part, wherein the circular orifice provided by the exit of the first part defines an inlet into the collecting vessel and has a diameter which is smaller than the diameter of the collecting vessel at the upper end thereof, and wherein the collecting vesselcontains a moveable closure member (13) for blocking the inlet into the collecting vesselwhich moveable closure member is capable of floating in urine and is adapted such that, in use, it blocks the inlet into the collecting vessel on the filling of the collecting vessel with urine so as to cause further voided urine to be collected in the urine collection body of the first part. By use of the device, a sample of first pass urine, undiluted by midstream urine, may be collected for medical analysis.
摘要翻译：用于收集由尿液的中游部分隔离的供体排出的尿液的第一通过部分的样品的装置包括第一部分（1），其在其上端（4）处包括适于接收由供体排出的尿的开口，在上端下游的尿液收集体（3）和位于尿液收集体下游的第一部分的下端（5）处的可封闭出口（6），所述出口提供圆形孔口（7），第二部分（2）位于第一部分的出口的下游，并且包括与第一部分的出口连通的收集容器（10），其中由第一部分的出口提供的圆形孔口限定入口进入收集容器并且其直径小于其上端处的收集容器的直径，并且其中收集容器包含可移动的封闭构件（13），用于阻止入口进入收集容器，可移动关闭构件是能够漂浮在尿液中，并且适于使得在使用时，在用尿液填充收集容器时阻止入口进入收集容器，以便使进一步排尿的尿液被收集在第一部分的尿液收集体中。通过使用该装置，可以采集未经中流尿液稀释的第一通尿样品进行医学分析。

3. 发明申请

WO2012066310A1 STAND FOR MICROPLATES 审中-公开
标题翻译：微波炉台架
公开(公告)号：WO2012066310A1
公开(公告)日：2012-05-24
申请号：PCT/GB2011/052193
申请日：2011-11-11
申请人： ABEL APPLICATIONS LIMITED , KNIGHT, Jan , KNIGHT, Robert
发明人： KNIGHT, Jan , KNIGHT, Robert
IPC分类号： B01L9/00
CPC分类号： B01L9/523 , B01L2200/087
摘要： A laboratory stand for a microplate comprises a base (2), at least one post (3, 4) extending upwardly from the base, a shelf (5) located above the base and supported by the at least one post, and means for adjusting the height of the shelf in relation to the base. The shelf (5) comprises a rear portion (9) which is substantially horizontal and a front portion (10), which is inclined downwards away from the horizontal, which is adapted to retain at least one microplate, The laboratory stand improves pipetting ergonomics.
摘要翻译：用于微孔板的实验室支架包括基部（2），从基部向上延伸的至少一个柱（3,4），位于基部上方并由至少一个支柱支撑的搁架（5），以及用于调节货架相对于底座的高度。搁架（5）包括基本水平的后部部分（9）和与水平方向向下倾斜的前部（10），其适于保持至少一个微孔板。实验室支架改善移液人体工程学。

4. 发明申请

WO2012027065A2 COMBINATION THERAPY FOR TREATMENT OF DISEASE 审中-公开
标题翻译：治疗疾病的联合治疗
公开(公告)号：WO2012027065A2
公开(公告)日：2012-03-01
申请号：PCT/US2011/045917
申请日：2011-07-29
申请人： CELGENE CORPORATION , KNIGHT, Robert , ALLES, Mark, J. , CIECHANOVER, Isaac
发明人： KNIGHT, Robert , ALLES, Mark, J. , CIECHANOVER, Isaac
IPC分类号： A61K38/22
CPC分类号： A61K31/454 , A61K38/179 , A61K45/06 , A61K2300/00
摘要： Provided herein are compositions comprising inhibitors of the Type II Activin Receptor ("ActRII") and kits comprising such compositions. Also provided herein are methods of treatment of disease comprising administration of one or more of the compositions described herein and administration of a second active agent.
摘要翻译：本文提供了包含II型活化素受体（“ActRII”）的抑制剂的组合物和包含此类组合物的试剂盒。本文还提供了治疗疾病的方法，其包括施用本文所述的一种或多种组合物和施用第二活性剂。

5. 发明申请

WO2012128817A2 OBTAINING POWER PROFILE INFORMATION WITH LOW OVERHEAD 审中-公开
标题翻译：获得低电压电源配置文件信息
公开(公告)号：WO2012128817A2
公开(公告)日：2012-09-27
申请号：PCT/US2011/068006
申请日：2011-12-30
申请人： INTEL CORPORATION , KNIGHT, Robert
发明人： KNIGHT, Robert
CPC分类号： G06F1/3206 , G06F1/3287 , G06F11/3024 , G06F11/3058 , G06F11/3093 , G06F2201/86 , G06F2201/88 , Y02D10/171 , Y02D50/20
摘要： In one embodiment, a method includes, upon occurrence of multiple power state transition events for a core of a multi-core processor, reading a value of a system counter of the core and values of low power counters of the core, without expiration of a timer or triggering of an interrupt. These values can be stored in a storage of the processor. Then, after collection is completed, the storage can be accessed to determine a power profile of the processor using the stored values. Other embodiments are described and claimed.
摘要翻译：在一个实施例中，一种方法包括在多核处理器的核心发生多个功率状态转换事件时，读取核心的系统计数器的值和核心的低功率计数器的值，而不会使定时器或触发中断。这些值可以存储在处理器的存储器中。然后，在收集完成之后，可以访问存储器以使用存储的值确定处理器的功率曲线。描述和要求保护其他实施例。

6. 发明申请

WO2007038800A2 PROFILING USING A USER-LEVEL CONTROL MECHANISM 审中-公开
标题翻译：使用用户级控制机制进行概要分析
公开(公告)号：WO2007038800A2
公开(公告)日：2007-04-05
申请号：PCT/US2006/038898
申请日：2006-10-02
申请人： INTEL CORPORATION , NEWBURN, Chris , WANG, Hong , ZOU, Xiang , KNIGHT, Robert , CHERNOFF, Anton , GEVA, Robert
发明人： NEWBURN, Chris , WANG, Hong , ZOU, Xiang , KNIGHT, Robert , CHERNOFF, Anton , GEVA, Robert
CPC分类号： G06F9/30003 , G06F11/3466 , G06F2201/86 , G06F2201/88
摘要： In one embodiment, the present invention is directed to a system that includes an optimization unit to optimize a code segment, and a profiler coupled to the optimization unit. The optimization unit may include a compiler and a profile controller. Further, the profiler may be used to request programming of a channel with a scenario for collection of profile data during execution of the code segment. Other embodiments are described and claimed.
摘要翻译：在一个实施例中，本发明针对一种系统，该系统包括用于优化代码段的优化单元以及耦合到优化单元的分析器。优化单元可以包括编译器和简档控制器。此外，剖析器可以用于请求在执行代码段期间利用用于收集简档数据的场景对信道进行编程。描述并要求保护其他实施例。

7. 发明申请

WO2013013180A1 BIOMECHANICS AWARE PROTECTIVE GEAR 审中-公开
标题翻译：生物医学保护齿轮
公开(公告)号：WO2013013180A1
公开(公告)日：2013-01-24
申请号：PCT/US2012/047662
申请日：2012-07-20
申请人： KNIGHT, Robert
发明人： KNIGHT, Robert
IPC分类号： A42B3/00
CPC分类号： A42B3/064 , A41D13/015 , A42B3/04 , A42B3/063 , A42B3/08 , A42B3/12 , A42B3/121 , A42B3/125 , A42B3/14 , A42B3/20 , A42B3/22 , A42C2/007
摘要： Protective gear includes an outer shell layer connected to a middle shell layer through an outer energy and impact transformer layer. The middle shell layer is connected to an inner shell layer through an inner energy and impact transformer layer. The outer and inner energy and impact transformer layers flexibly connect the shell layers to absorb impact forces, rotational forces, shear forces, etc., and allow the various shell layers to move and slide relative to the other shell layers. The outer and inner energy and impact transformer layers may be constructed using gels, fluids, eleetro-rheological elements, magneto- theological elements, etc. The protective gear may be formed as helmets or body protection for various activities and protect users from not only impact and penetrative forces, but rotational and shear forces as well.
摘要翻译：保护齿轮包括通过外部能量和冲击变压器层连接到中间壳层的外壳层。中间壳层通过内部能量和冲击变压器层连接到内壳层。外部和内部能量和冲击变压器层灵活地连接壳层以吸收冲击力，旋转力，剪切力等，并允许各种壳层相对于其它壳层移动和滑动。外部和内部能量和内部能量和冲击变压器层可以使用凝胶，流体，电子流变元件，磁致辞元件等构成。保护装置可以形成为头盔或身体保护用于各种活动，并且保护用户不仅不受影响和穿透力，但旋转力和剪切力也是如此。

8. 发明申请

WO2004016820A3 THIN FILM DEPOSITION APPARATUS 审中-公开
公开(公告)号：WO2004016820A3
公开(公告)日：2004-02-26
申请号：PCT/GB2003/003526
申请日：2003-08-13
申请人： OXFORD INSTRUMENTS PLASMA TECHNOLOGY LIMITED , GEORGE, Christopher , WATSON, Michael , KNIGHT, Robert , HALSALL, Brian , JOLLY, Timothy
发明人： GEORGE, Christopher , WATSON, Michael , KNIGHT, Robert , HALSALL, Brian , JOLLY, Timothy
IPC分类号： C23C14/54
摘要： Thin film deposition apparatus comprises a processing chamber (1) within which is mounted a movable substrate support (5). Monitoring apparatus has an aligned radiation emitter and radiation receiver (13, 15, 14, 16) mounted on the substrate support (5) and located in use on opposite sides of a substrate on the support, and a processing system (36) for monitoring radiation received by the radiation receiver.

9. 发明申请

WO2002082753A1 ROBUST RADIO BASE STATION CONTROLLER ARCHITECTURE 审中-公开
标题翻译：坚固无线电基站控制器架构
公开(公告)号：WO2002082753A1
公开(公告)日：2002-10-17
申请号：PCT/US2002/001834
申请日：2002-01-17
申请人： TELEFONAKTIEBOLAGET LM ERICSSON , PALAKODETY, Ravi , CHUN, Dexter , KNIGHT, Robert , LEE, Kuo-Chun
发明人： PALAKODETY, Ravi , CHUN, Dexter , KNIGHT, Robert , LEE, Kuo-Chun
IPC分类号： H04L12/56
CPC分类号： H04W24/04 , H04W88/12
摘要： A base station controller system comprises a high data rate distributed switching fabric providing flexible access to call processing resource pools. The arrangement permits a system controller to selectively assign specific resources depending on call type based on configuring the distributed switching fabric. The transport links comprising the distributed switching fabric provide redundant access to each of the resource pools, greatly reducing the portion of overall call processing capability lost with a single failure. Preferably, the distributed switching fabric comprises a central ATM switch and a number of distributed ATM switches interconnecting the resource pools to the central switching resource. The system may adopt a rack arrangement wherein a processing subrack includes the mix of different processing resources necessary to support substantially all call flow processing for one or more types of calls. The system's call capacity is thus easily scalable based on adding additional processing subracks.
摘要翻译：基站控制器系统包括提供对呼叫处理资源池的灵活接入的高数据速率分布式交换结构。该配置允许系统控制器基于配置分布式交换结构来根据呼叫类型选择性地分配特定资源。包括分布式交换结构的传输链路提供对每个资源池的冗余访问，大大减少了单个故障损失的整体呼叫处理能力的部分。优选地，分布式交换结构包括中央ATM交换机和将资源池互连到中央交换资源的多个分散式ATM交换机。系统可以采用机架布置，其中处理框包括用于支持一种或多种类型呼叫的基本上所有呼叫流处理所必需的不同处理资源的混合。因此，系统的呼叫容量可以通过添加额外的处理支架来轻松扩展。

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