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1. 发明申请

WO2006104505A3 SEAT BELT PRETENSIONER 审中-公开
标题翻译：座椅皮带前卫
公开(公告)号：WO2006104505A3
公开(公告)日：2008-12-04
申请号：PCT/US2005026156
申请日：2005-07-22
申请人： KEY SAFETY SYSTEMS INC , BELL JOHN , JACK BRIAN A
发明人： BELL JOHN , JACK BRIAN A
IPC分类号： B60R22/36
CPC分类号： B60R22/1952 , B60R22/22
摘要： A seat belt pretensioner acts upon the sill end of a three point seat belt. A fixed member (79) of the pretensioner is adapted to be fixed to a load bearing part of the vehicle. A movable member (99) is connected to the sill end of the seat belt (14) and is slideable with respect to the fixed member. The movable member (99) is moved in a direction that is longitudinal relative to the fixed member (79) to move the sill end of the seat belt in a pretensioning direction in response to a signal from the crash sensor. In this way the sill end of the seat belt is free to move along a connecting member when the seat belt is not under tension either from use in restraining a seat occupant and/or from a pretensioning operation.
摘要翻译：一个安全带预紧器作用在三点式安全带的门槛端。预紧器的固定构件（79）适于固定在车辆的承载部分上。可动构件（99）连接到座椅安全带（14）的门槛端，并且能够相对于固定构件滑动。可移动构件（99）沿相对于固定构件（79）纵向的方向移动，以响应于来自碰撞传感器的信号沿预张紧方向移动座椅安全带的门槛端。以这种方式，当安全带不受张力时，安全带的门槛端可以沿着连接构件自由移动，不能用于限制座椅乘员和/或预张紧操作。

2. 发明申请

WO2006019607A2 SEAT BELT PRETENSIONER 审中-公开
标题翻译：座椅皮带预紧器
公开(公告)号：WO2006019607A2
公开(公告)日：2006-02-23
申请号：PCT/US2005024191
申请日：2005-07-11
申请人： KEY SAFETY SYSTEMS INC , BELL JOHN , JACK BRIAN A , BLACKADDER DAVID
发明人： BELL JOHN , JACK BRIAN A , BLACKADDER DAVID
CPC分类号： B60R22/1952 , B60R22/22
摘要： A pretensioner for a three point seat belt has a cylinder (79) adapted to be attached to a structural member of the vehicle and a piston disposed within the cylinder (79). The piston can move translationally relative to the cylinder (79) in a pretensioning direction. A flexible member (50) is arranged in a curved profile with a seat belt webbing being attached to the flexible member. The flexible member (50) has a first end that can be pulled by the piston and a second end releasably connected to an exterior of the cylinder (79) such that when the piston moves translationally relative to the cylinder (79) the second end of the flexible member (50) moves translationally relative to the cylinder (79) along the exterior of the cylinder (79).
摘要翻译：三点式座椅安全带的预紧器具有适于连接到车辆的结构构件的气缸（79）和设置在气缸（79）内的活塞。活塞可以在预张紧方向上相对于缸体（79）平移移动。柔性构件（50）以弯曲轮廓布置，座椅安全带带子附接到柔性构件。柔性构件（50）具有能够被活塞拉动的第一端部和可释放地连接到缸体（79）的外部的第二端部，使得当活塞相对于缸体（79）平移时，第二端部柔性构件50沿着缸体79的外部相对于缸体79平移移动。

3. 发明申请

WO2005067444A3 SEAT BELT RETRACTOR 审中-公开
标题翻译：座椅带扣
公开(公告)号：WO2005067444A3
公开(公告)日：2007-10-25
申请号：PCT/US2004030062
申请日：2004-09-13
申请人： KEY SAFETY SYSTEMS INC , BELL JOHN , JACK BRIAN A , PALLISER MARTYN
发明人： BELL JOHN , JACK BRIAN A , PALLISER MARTYN
IPC分类号： B60R22/36 , B60R22/28 , B60R22/34
CPC分类号： B60R22/3413 , B60R2022/286 , B60R2022/287 , B60R2022/288
摘要： A seat belt retractor comprising: a spool (1) mounted for rotation on the retractor, for retraction or pay-out of seat-belt webbing (11) depending upon the rotation direction of the spool (1); means (13a, 13b) for locking the spool against rotation when a crash is sensed; force limiting means (2, 8) for allowing further pay-out of the seat belt webbing (11) after the spool (1) has locked, under the influence of a vehicle occupant's forward momentum. The force limiting means comprises a first resilient means (2) disposed in the force path between the spool (1) and the locking means, and a second resilient means comprising a wire (8) releasably held in the force path between the spool (1) and the locking means by a locking plate (6) engaged with the locking means, wherein the wire is released from the force path by disengagement between the locking plate (6) and the locking means (13a, 13b).
摘要翻译：一种安全带卷收器，包括：卷轴（1），其安装成用于在牵开器上旋转，用于根据卷轴（1）的旋转方向缩回或放出安全带织带（11）; 用于在感测到碰撞时将所述阀芯锁定以防旋转的装置（13a，13b）; 力限制装置（2,8），用于在车辆乘员的向前动量的影响下，在阀芯（1）锁定之后允许安全带织带（11）进一步发放。力限制装置包括设置在卷轴（1）和锁定装置之间的力路径中的第一弹性装置（2）和第二弹性装置，其包括可释放地保持在卷轴（1）之间的力路径中的线（8））和通过与锁定装置接合的锁定板（6）的锁定装置，其中通过在锁定板（6）和锁定装置（13a，13b）之间的脱离而将电线从力路径释放。

4. 发明申请

WO2006014829A3 SEAT BELT PRETENSIONER 审中-公开
标题翻译：座椅皮带前卫
公开(公告)号：WO2006014829A3
公开(公告)日：2007-07-05
申请号：PCT/US2005026155
申请日：2005-07-22
申请人： KEY SAFETY SYSTEMS INC , BELL JOHN , JACK BRIAN A
发明人： BELL JOHN , JACK BRIAN A
IPC分类号： B60R22/00 , B60R22/20 , B60R22/36
CPC分类号： B60R22/1952 , B60R22/22
摘要： A pretensioner for a three point seat belt has a cylinder adapted to be attached to a structural member of a vehicle and a piston disposed within the cylinder. A pyrotechnic means (22) moves the piston in a direction that is longitudinal relative to the cylinder in a pretensioning direction (A). A slider bar (10) is oriented substantially parallel to a longitudinal axis of the cylinder. A seat belt webbing (14) is looped around the slider bar (10) such that the seat belt webbing can freely move along a portion of the slider bar that is oriented substantially parallel to a longitudinal axis of the cylinder so long as the pyrotechnic means for moving the piston has not been activated. A cable (20) extends from the piston and loops around the seat belt webbing (14) to cause the seat belt webbing to move along the slider bar (10) in a pretensioning direction (A) when the pyrotechnic means (22) for moving the piston is activated.
摘要翻译：用于三点式安全带的预紧器具有适于附接到车辆的结构构件和设置在气缸内的活塞的气缸。烟火装置（22）在预张紧方向（A）上沿相对于气缸纵向的方向移动活塞。滑杆（10）被定向成基本上平行于气缸的纵向轴线。安全带安全带（14）围绕滑块（10）环绕，使得座椅安全带织带可以沿着滑块的一部分自由移动，该滑杆基本上平行于圆柱体的纵向轴线定向，只要烟火装置用于移动活塞尚未激活。当用于移动的烟火装置（22）时，电缆（20）从活塞延伸并环绕安全带织带（14）旋转，以使安全带织带沿预拉伸方向（A）沿着拉杆（10）移动活塞被激活。

5. 发明申请

WO2007008378A8 SEAT BELT PRETENSIONER 审中-公开
标题翻译：座椅皮带前卫
公开(公告)号：WO2007008378A8
公开(公告)日：2007-11-22
申请号：PCT/US2006024669
申请日：2006-06-23
申请人： KEY SAFETY SYSTEMS INC , BELL JOHN
发明人： BELL JOHN
IPC分类号： B60R22/195
CPC分类号： B60R22/1951 , B60R22/26 , B60R2022/263
摘要： A pretensioning apparatus (6) for seat belt webbing (2) at a belt anchor end (3) of a three point vehicle safety restraint seat belt. The pretensioning apparatus (6) has a fixed member in the form of a cylinder (7) that may be anchored to a vehicle seat (1 ) at the belt anchor side of the vehicle. A movable member in the form of a piston (13) is connected to the webbing (2) in the region of the belt anchor end (3). A means is provided for moving the movable member relative to the fixed member in a generally horizontal direction, to move the seat belt webbing (2) in a pretensioning direction in response to a signal from a crash sensor. A webbing guide (11) is fixed to the seat (1) to provide an effective anchorage point spaced from the belt anchor end (3) of the webbing under pretensioning conditions.
摘要翻译：一种用于三点式车辆安全带安全带的安全带安全带（3）的安全带安全带（2）的预张紧装置（6）。预张紧装置（6）具有可以在车辆的带固定器侧被固定到车辆座椅（1）的气缸（7）形式的固定构件。活塞（13）形式的可动构件在带锚固端（3）的区域中连接到织带（2）。提供了一种用于在大致水平方向上相对于固定构件移动可移动构件的装置，以响应于来自碰撞传感器的信号使安全带织带（2）沿预张紧方向移动。安全带引导件（11）固定在座椅（1）上，以在预拉伸条件下提供与织带的带固定端（3）间隔开的有效锚固点。

6. 发明申请

WO2012094386A9 GENERATION OF ANTIBODIES TO TUMOR ANTIGENS AND GENERATION OF TUMOR SPECIFIC COMPLEMENT DEPENDENT CYTOTOXICITY BY ADMINISTRATION OF ONCOLYTIC VACCINIA VIRUS 审中-公开
标题翻译：抗肿瘤抗生素的产生和肿瘤特异性补体的产生依赖于毒蕈碱疫苗病毒的依赖性细胞毒性
公开(公告)号：WO2012094386A9
公开(公告)日：2013-08-15
申请号：PCT/US2012020173
申请日：2012-01-04
申请人： JENNEREX INC , KIRN DAVID , BELL JOHN , BREITBACH CAROLINE , MOON ANNE , HWANG TAE-HO , LEE YU KYOUNG , KIM MI-KYUNG , SILLAJEN INC
发明人： KIRN DAVID , BELL JOHN , BREITBACH CAROLINE , MOON ANNE , HWANG TAE-HO , LEE YU KYOUNG , KIM MI-KYUNG
IPC分类号： A61K39/12
CPC分类号： A61K39/285 , A61K35/26 , A61K35/76 , A61K35/761 , A61K35/763 , A61K35/768 , A61K39/0011 , A61K39/12 , A61K39/125 , A61K39/145 , A61K39/165 , A61K39/17 , A61K39/205 , A61K39/235 , A61K39/245 , A61K39/395 , A61K45/06 , A61K2039/505 , A61K2039/507 , A61K2039/55522 , C07K16/18 , C07K16/30 , C07K2317/14 , C07K2317/734 , C12N7/00 , C12N2710/10034 , C12N2710/16632 , C12N2710/16634 , C12N2710/24034 , C12N2710/24132 , C12N2720/12232 , C12N2750/14034 , C12N2760/16034 , C12N2760/18134 , C12N2760/18434 , C12N2760/18734 , C12N2760/20034 , C12N2760/20232 , C12N2770/32034 , C12N2770/32334 , C12N2770/36034 , G01N33/574
摘要： The present invention relates to methods and compositions for use in inducing tumor-specific antibody mediated complement-dependent cytotoxic response in an animal having a tumor comprising administering to said animal a composition comprising a replication competent oncolytic virus wherein administration of the composition induces in the animal production of antibodies that mediate a CDC response specific to said tumor.
摘要翻译：本发明涉及用于在具有肿瘤的动物中诱导肿瘤特异性抗体介导的补体依赖性细胞毒性应答的方法和组合物，所述方法和组合物包括向所述动物施用包含可复制的溶瘤病毒的组合物，其中组合物在动物中的诱导产生介导对所述肿瘤特异性的CDC反应的抗体。

7. 发明申请

WO2009016433A2 ONCOLYTIC RHABDOVIRUS 审中-公开
公开(公告)号：WO2009016433A2
公开(公告)日：2009-02-05
申请号：PCT/IB2007004701
申请日：2007-09-17
申请人： OTTAWA HEALTH RESEARCH INST , STOJDL DAVID , BROWN CHRISTOPHER , BELL JOHN
发明人： STOJDL DAVID , BROWN CHRISTOPHER , BELL JOHN
IPC分类号： A61K35/766
CPC分类号： A61K35/766 , A61K35/761 , A61K35/763 , A61K35/768 , A61K45/06 , C12N7/00 , C12N2760/20032 , C12N2760/20045 , C12N2760/20221 , C12N2760/20222 , C12N2760/20232 , C12N2760/20271 , C12N2810/6081
摘要： Embodiments of the invention include compositions and methods related to non-VSV rhabdoviruses and their use as anti-cancer therapeutics. Such rhabdo viruses possess tumor cell killing properties in vitro and in vivo.
摘要翻译：本发明的实施方案包括与非VSV弹状病毒相关的组合物和方法及其作为抗癌治疗剂的用途。这种狂犬病毒在体外和体内具有肿瘤细胞杀伤性质。

8. 发明申请

WO2007050780A2 NEUROLOGIC SYSTEM AND ASSOCIATED METHODS 审中-公开
标题翻译：神经系统及相关方法
公开(公告)号：WO2007050780A2
公开(公告)日：2007-05-03
申请号：PCT/US2006041826
申请日：2006-10-24
申请人： BELL JOHN
发明人： BELL JOHN
IPC分类号： A61B5/04
CPC分类号： A61B5/0484 , A61B5/02405 , A61B5/0402 , A61B5/16 , A61B5/165 , A61B5/4041 , A61N1/36017 , A61N1/36021 , A61N1/36071
摘要： The present invention includes systems and methods for assessing stimulatory effects on a neurologic system. One method may include steps of stimulating the neurologic system, monitoring at least one neurologic state for effects of the stimulation to the neurologic system, gathering multi-dimensional data from the monitoring of the at least one neurological state, and analyzing the multi-dimensional data to determine multi-dimensional interactions between the stimulation and the effects on the at least one neurological state. Various neurologic states are considered to be within the scope of the present invention, including, without limitation, hypnotic, analgesia, relaxation, stress, depression, anxiety, allostasis, immune response, and combinations thereof.
摘要翻译：本发明包括用于评估对神经系统的刺激作用的系统和方法。一种方法可以包括以下步骤：刺激神经系统，监测刺激对神经系统的影响的至少一种神经状态，从监测至少一种神经状态收集多维数据，以及分析多维数据以确定刺激与对至少一种神经状态的影响之间的多维相互作用。认为各种神经系统状态在本发明的范围内，包括但不限于催眠，止痛，松弛，压力，抑郁，焦虑，异常，免疫应答及其组合。

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