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1. 发明申请

WO2006062892A3 LOW PROFILE INSTRUMENT IMMOBILIZER 审中-公开
标题翻译：低剖面仪器固定器
公开(公告)号：WO2006062892A3
公开(公告)日：2009-04-16
申请号：PCT/US2005043913
申请日：2005-12-06
申请人： IMAGE GUIDED NEUROLOGICS INC , SKAKOON JAMES G , SOLAR MATTHEW S , MILLER THOMAS I , HELMER PATRICK R , FREAS MARK STEPHEN
发明人： SKAKOON JAMES G , SOLAR MATTHEW S , MILLER THOMAS I , HELMER PATRICK R , FREAS MARK STEPHEN
IPC分类号： A61B19/00
CPC分类号： A61M25/02 , A61B5/6864 , A61B17/3415 , A61B17/3423 , A61B90/11 , A61B90/50 , A61B2017/347 , A61B2090/103 , A61N1/0536 , A61N1/0539
摘要： This document discusses, among other things, examples of a low profile instrument immobilizer and means for positioning the same. In one example, the low profile instrument immobilizer grasps, secures, and immobilizes an electrode or other instrument that extends through a burr hole in a skull to a target location in a patient's brain.
摘要翻译：本文件尤其讨论了一种低调仪器防盗器的示例和用于定位它的装置。在一个示例中，低调仪器固定器抓住，固定和固定延伸穿过颅骨中的钻孔的电极或其它器械到患者大脑中的目标位置。

2. 发明申请

WO2005030075A3 BALL AND SOCKET TRAJECTORY GUIDE 审中-公开
标题翻译：球和脚手架指南
公开(公告)号：WO2005030075A3
公开(公告)日：2005-07-28
申请号：PCT/US2004031109
申请日：2004-09-23
申请人： IMAGE GUIDED NEUROLOGICS INC , SOLAR MATTHEW S , SKAKOON JAMES G , PARMER KARI , MILLER THOMAS I , FREAS MARK STEPHEN
发明人： SOLAR MATTHEW S , SKAKOON JAMES G , PARMER KARI , MILLER THOMAS I , FREAS MARK STEPHEN
IPC分类号： A61B17/60 , A61B19/00 , A61B17/80
CPC分类号： A61B90/11 , A61B34/20 , A61B2017/603 , A61B2090/062 , Y10T29/49826
摘要： An alignment device and method is provided. Higher precision is achieved when fixing an orientation of an insertion axis using alignment devices shown. A symmetric clamping force is provided that reduces or eliminates unwanted displacement after the desired orientation is obtained. Another feature includes increased flexibility to use a variety of primary medical devices. Another feature includes a standoff feature that reduces tissue damage. Another feature includes an orienting fixture for image guided procedures.
摘要翻译：提供了一种对准装置和方法。使用所示的对准装置固定插入轴的取向时可获得更高的精度。提供了对称的夹紧力，其在获得期望的取向之后减少或消除不期望的位移。另一个特征包括增加使用各种主要医疗设备的灵活性。另一个特征包括减少组织损伤的间隔特征。另一特征包括用于图像引导程序的定向夹具。

3. 发明申请

WO0176498A9 DEEP ORGAN ACCESS DEVICE AND METHOD 审中-公开
标题翻译：深层器官访问设备和方法
公开(公告)号：WO0176498A9
公开(公告)日：2003-10-09
申请号：PCT/US0111178
申请日：2001-04-06
申请人： IMAGE GUIDED NEUROLOGICS INC , MAYO FOUNDATION , SKAKOON JAMES G , WHAREN ROBERT , SOLAR MATTHEW S , PARMER KARI , MAZZOCCHI RUDY A , DAVID JOHN , MURDOCK FRANK , HATCHER DAVID , MILLER THOMAS I , PARMER TIMOTHY ALAN , TRUWIT CHARLES L
发明人： SKAKOON JAMES G , WHAREN ROBERT , SOLAR MATTHEW S , PARMER KARI , MAZZOCCHI RUDY A , DAVID JOHN , MURDOCK FRANK , HATCHER DAVID , MILLER THOMAS I , PARMER TIMOTHY ALAN , TRUWIT CHARLES L
IPC分类号： A61B17/00 , A61B17/34 , A61B19/00 , A61M1/00
CPC分类号： A61N1/0539 , A61B34/20 , A61B90/11 , A61B2017/0023 , A61B2017/00398 , A61B2017/00911 , A61B2017/3407 , A61B2017/3409 , A61B2017/3411 , A61B2017/347 , A61B2034/2051 , A61B2034/2055 , A61B2090/103 , A61B2090/363 , A61B2090/374 , A61B2090/3762 , A61B2090/3983 , A61N1/0534
摘要： Devices and methods provide accurate targeting, placement, and/or stabilization of an electrode or other instrument(s) into the brain or other body organ, such as to treat severe tremor or other neurological disorders. Targeting is performed using any form of image-guidance, including real-time MRI, CT, or frameless surgical navigation systems.
摘要翻译：装置和方法提供将电极或其他器械精确地靶向，放置和/或稳定到脑或其他身体器官中，例如治疗严重的震颤或其它神经障碍。使用任何形式的图像引导进行定向，包括实时MRI，CT或无框架手术导航系统。

4. 发明申请

WO0176676A3 MEDICAL DEVICE INTRODUCER 审中-公开
标题翻译：医疗器械介绍
公开(公告)号：WO0176676A3
公开(公告)日：2002-03-21
申请号：PCT/US0140458
申请日：2001-04-06
申请人： IMAGE GUIDED NEUROLOGICS INC , SKAKOON JAMES G , MILLER THOMAS I , SOLAR MATTHEW S , MILLS GERALD W , TRUWIT CHARLES L
发明人： SKAKOON JAMES G , MILLER THOMAS I , SOLAR MATTHEW S , MILLS GERALD W , TRUWIT CHARLES L
IPC分类号： A61B17/00 , A61B17/34 , A61B19/00
CPC分类号： A61N1/0539 , A61B34/20 , A61B90/11 , A61B2017/0023 , A61B2017/00398 , A61B2017/00911 , A61B2017/3407 , A61B2017/3409 , A61B2017/3411 , A61B2017/347 , A61B2034/2051 , A61B2034/2055 , A61B2090/103 , A61B2090/363 , A61B2090/374 , A61B2090/3762 , A61B2090/3983 , A61N1/0534
摘要： An introducer is described that is coupled to a patient, specifically a patient's skull. The introducer may include an advancer that is remote from the patient, the advancer communicating with the introducer by means of a cable system. The introducer may also include a local position sensor that indicates the position of the primary medical device being introduced. The introducer may also include a frameless reference system that locates the primary medical device relative to a table that the patient is fixed to.
摘要翻译：描述了与患者，特别是患者的头骨联接的导引器。导引器可以包括远离患者的推进器，推进器借助于电缆系统与引入器通信。导引器还可以包括指示被引入的主要医疗装置的位置的局部位置传感器。导引器还可以包括无框架参考系统，其定位主要医疗装置相对于患者被固定到的桌子。

5. 发明申请

WO0176498A2 DEEP ORGAN ACCESS DEVICE AND METHOD 审中-公开
标题翻译：深层器官访问设备和方法
公开(公告)号：WO0176498A2
公开(公告)日：2001-10-18
申请号：PCT/US0111178
申请日：2001-04-06
申请人： IMAGE GUIDED NEUROLOGICS INC , SKAKOON JAMES G , WHAREN ROBERT , SOLAR MATTHEW S , PARMER KARI , MAZZOCCHI RUDY A , DAVID JOHN , MURDOCK FRANK , HATCHER DAVID , MILLER THOMAS I , PARMER TIMOTHY ALAN , TRUWIT CHARLES L
发明人： SKAKOON JAMES G , WHAREN ROBERT , SOLAR MATTHEW S , PARMER KARI , MAZZOCCHI RUDY A , DAVID JOHN , MURDOCK FRANK , HATCHER DAVID , MILLER THOMAS I , PARMER TIMOTHY ALAN , TRUWIT CHARLES L
IPC分类号： A61B17/00 , A61B17/34 , A61B19/00
CPC分类号： A61N1/0539 , A61B34/20 , A61B90/11 , A61B2017/0023 , A61B2017/00398 , A61B2017/00911 , A61B2017/3407 , A61B2017/3409 , A61B2017/3411 , A61B2017/347 , A61B2034/2051 , A61B2034/2055 , A61B2090/103 , A61B2090/363 , A61B2090/374 , A61B2090/3762 , A61B2090/3983 , A61N1/0534
摘要： Devices and methods provide accurate targeting, placement, and/or stabilization of an electrode or other instrument(s) into the brain or other body organ, such as to treat severe tremor or other neurological disorders. Targeting is performed using any form of image-guidance, including real-time MRI, CT, or frameless surgical navigation systems.
摘要翻译：装置和方法提供将电极或其他器械精确地靶向，放置和/或稳定到脑或其他身体器官中，例如治疗严重的震颤或其它神经障碍。使用任何形式的图像引导进行定向，包括实时MRI，CT或无框架外科导航系统。

6. 发明申请

WO0176498B1 DEEP ORGAN ACCESS DEVICE AND METHOD 审中-公开
标题翻译：深度的器官存取装置和方法
公开(公告)号：WO0176498B1
公开(公告)日：2002-06-27
申请号：PCT/US0111178
申请日：2001-04-06
申请人： IMAGE GUIDED NEUROLOGICS INC , SKAKOON JAMES G , WHAREN ROBERT , SOLAR MATTHEW S , PARMER KARI , MAZZOCCHI RUDY A , DAVID JOHN , MURDOCK FRANK , HATCHER DAVID , MILLER THOMAS I , PARMER TIMOTHY ALAN , TRUWIT CHARLES L
发明人： SKAKOON JAMES G , WHAREN ROBERT , SOLAR MATTHEW S , PARMER KARI , MAZZOCCHI RUDY A , DAVID JOHN , MURDOCK FRANK , HATCHER DAVID , MILLER THOMAS I , PARMER TIMOTHY ALAN , TRUWIT CHARLES L
IPC分类号： A61B17/00 , A61B17/34 , A61B19/00 , A61M1/00
CPC分类号： A61N1/0539 , A61B34/20 , A61B90/11 , A61B2017/0023 , A61B2017/00398 , A61B2017/00911 , A61B2017/3407 , A61B2017/3409 , A61B2017/3411 , A61B2017/347 , A61B2034/2051 , A61B2034/2055 , A61B2090/103 , A61B2090/363 , A61B2090/374 , A61B2090/3762 , A61B2090/3983 , A61N1/0534
摘要： Devices and methods provide accurate targeting, placement, and/or stabilization of an electrode or other instrument(s) into the brain or other body organ, such as to treat severe tremor or other neurological disorders. Targeting is performed using any form of image-guidance, including real-time MRI, CT, or frameless surgical navigation systems.
摘要翻译：装置和方法提供电极或其他器械到大脑或其他身体器官的精确瞄准，放置和/或稳定，例如治疗严重震颤或其他神经疾病。使用任何形式的图像引导进行定位，包括实时MRI，CT或无框手术导航系统。

7. 发明申请

WO2006062824A3 INSTRUMENT GUIDING STAGE APPARATUS AND METHOD FOR USING SAME 审中-公开
标题翻译：仪器指导装置及其使用方法
公开(公告)号：WO2006062824A3
公开(公告)日：2009-04-23
申请号：PCT/US2005043651
申请日：2005-12-02
申请人： IMAGE GUIDED NEUROLOGICS INC , SOLAR MATTHEW S , MILLER THOMAS I , SKAKOON JAMES G
发明人： SOLAR MATTHEW S , MILLER THOMAS I , SKAKOON JAMES G
IPC分类号： A61B19/00
CPC分类号： A61B90/11 , A61B34/20
摘要： This documents describes among other things a normalizing stage apparatus, tools and methods. One example includes a base that defines a trajectory. A first stage is moveably coupled to the base and the first stage moves along the trajectory. A second stage is moveably coupled to the first stage and moves an instrument coupled thereto with respect to the base and the first stage. Before movement of the instrument, the first and second stages are in first positions desired (e.g. predetermined) distances from a target area in the body. Another example includes the first stage and a guide tube stop coupled with the first stage. A guide tube is coupled with the guide tube stop and extends through a guide tube stop lumen. The guide tubes outer perimeter is dimensioned and configured to snugly couple with the surface defining the guide tube stop lumen.
摘要翻译：本文件描述了归一化阶段装置，工具和方法。一个例子包括定义轨迹的基座。第一阶段可移动地联接到基座，并且第一阶段沿轨迹移动。第二阶段可移动地联接到第一阶段并且移动相对于基座和第一平台耦合到其上的仪器。在仪器移动之前，第一和第二阶段处于从身体中的目标区域所需的（例如预定的）距离的第一位置。另一个例子包括第一阶段和与第一阶段联接的导管停止。引导管与引导管止动件连接并延伸穿过导管止动腔。引导管外周的尺寸和构造使其与限定引导管止血腔的表面紧密耦合。

8. 发明申请

WO2004026161A3 LOW PROFILE INSTRUMENT IMMOBILIZER 审中-公开
标题翻译：低剖面仪器固定器
公开(公告)号：WO2004026161A3
公开(公告)日：2004-07-01
申请号：PCT/US0328966
申请日：2003-09-17
申请人： IMAGE GUIDED NEUROLOGICS INC , SKAKOON JAMES G , SOLAR MATHEW S , MILLER THOMAS I , HELMER PAT , FREAS MARK
发明人： SKAKOON JAMES G , SOLAR MATHEW S , MILLER THOMAS I , HELMER PAT , FREAS MARK
IPC分类号： A61B19/00 , A61M25/02
CPC分类号： A61B5/6864 , A61B90/11 , A61B90/50 , A61B2017/347 , A61B2090/103 , A61M25/02 , A61N1/0536 , A61N1/0539
摘要： This document discusses examples of a low profile instrument immobilizer, such as for grasping, securing, and immobilizing (100, 600, 1000, 1500, 1700, 1900, 2400 ) an electrode or other instrument that has been introduced to extend through a burr hole in a skull to a target location in a patient's brain.
摘要翻译：本文件讨论了一种低调仪器固定器的实例，例如用于抓住，固定和固定（100,6600,1000,1500,1700,1900,2400）的电极或其他仪器，其已被引入以延伸通过钻孔在头骨到患者大脑中的目标位置。

9. 发明申请

WO2004026161A8 LOW PROFILE INSTRUMENT IMMOBILIZER 审中-公开
标题翻译：低剖面仪器固定器
公开(公告)号：WO2004026161A8
公开(公告)日：2004-08-26
申请号：PCT/US0328966
申请日：2003-09-17
申请人： IMAGE GUIDED NEUROLOGICS INC , SKAKOON JAMES G , SOLAR MATHEW S , MILLER THOMAS I , HELMER PAT , FREAS MARK
发明人： SKAKOON JAMES G , SOLAR MATHEW S , MILLER THOMAS I , HELMER PAT , FREAS MARK
IPC分类号： A61B19/00 , A61M25/02
CPC分类号： A61B5/6864 , A61B90/11 , A61B90/50 , A61B2017/347 , A61B2090/103 , A61M25/02 , A61N1/0536 , A61N1/0539
摘要： This document discusses examples of a low profile instrument immobilizer, such as for grasping, securing, and immobilizing (100, 600, 1000, 1500, 1700, 1900, 2100 ) an electrode or other instrument that has been introduced to extend through a burr hole in a skull to a target location in a patient's brain.
摘要翻译：本文件讨论了一种低调仪器固定器的实例，例如用于抓住，固定和固定（100,6600,1000,1500,1700,1900,2100）的电极或其它仪器，其已经被引入以延伸通过钻孔在颅骨到患者大脑中的目标位置。

10. 发明申请

WO2006062806A2 MULTI-LUMEN INSTRUMENT GUIDE 审中-公开
标题翻译：多功能仪器指南
公开(公告)号：WO2006062806A2
公开(公告)日：2006-06-15
申请号：PCT/US2005043532
申请日：2005-12-02
申请人： IMAGE GUIDED NEUROLOGICS INC , MILLER THOMAS I , SKAKOON JAMES G
发明人： MILLER THOMAS I , SKAKOON JAMES G
IPC分类号： A61B19/00
CPC分类号： A61B90/11
摘要： This document discusses, among other things, a method of manufacture including a mold having at least one pin, and surrounding the pin with a hardenable material to form a first guide layer. The mold and pin are removed from the resulting first guide layer, to define a substantially untapered first instrument passage that corresponds to the geometry of the pin. Optionally, the first instrument passage includes at least five substantially untapered channels including a central channel. The first instrument passage of a stacked second guide layer. In a further example, the first and second guide layers are coupled to a guide coupler that cooperatively aligns the first and second instrument passages. The guide layers can be used with a trajectory guide for image guided surgery.
摘要翻译：本文件尤其涉及一种制造方法，其包括具有至少一个销的模具，并且用可硬化材料围绕销以形成第一引导层。将模具和销从所得到的第一引导层中移除，以限定对应于销的几何形状的基本上无缝的第一仪器通道。可选地，第一仪器通道包括至少五个基本上无缝的通道，包括中心通道。堆叠的第二引导层的第一仪器通道。在另一示例中，第一和第二引导层联接到协作地对准第一和第二仪器通道的引导耦合器。引导层可以与图像引导手术的轨迹指南一起使用。

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