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1. 发明申请

WO2007021494A3 ALBUMIN FUSION PROTEINS 审中-公开
标题翻译： ALBUMIN融合蛋白
公开(公告)号：WO2007021494A3
公开(公告)日：2007-07-26
申请号：PCT/US2006029391
申请日：2006-07-31
申请人： HUMAN GENOME SCIENCES INC , ROSEN CRAIG , BELL ADAM , MOORE PAUL , SHI YANGGU , LAFLEUR DAVID , LAIRD MICHAEL , HASELTINE WILLIAM , WOODS DOUGLAS , BOCK JASON , SUBRAMANIAN MANI
发明人： ROSEN CRAIG , BELL ADAM , MOORE PAUL , SHI YANGGU , LAFLEUR DAVID , LAIRD MICHAEL , HASELTINE WILLIAM , WOODS DOUGLAS , BOCK JASON , SUBRAMANIAN MANI
IPC分类号： C07K14/00
CPC分类号： C07K14/765 , A61K47/643 , C07K2319/00
摘要： The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors containing these nucleic acids, host cells transformed with these nucleic acids vectors, and methods of making the albumin fusion proteins of the invention and using these nucleic acids, vectors, and/or host cells. Additionally the present invention encompasses pharmaceutical compositions comprising albumin fusion proteins and methods of treating, preventing, or ameliorating diseases, disorders or conditions using albumin fusion proteins of the invention.
摘要翻译：本发明包括清蛋白融合蛋白。编码本发明的清蛋白融合蛋白的核酸分子也包括在本发明中，含有这些核酸的载体，用这些核酸载体转化的宿主细胞以及制备本发明的清蛋白融合蛋白并使用这些核酸的方法酸，载体和/或宿主细胞。此外，本发明涵盖包含清蛋白融合蛋白的药物组合物以及使用本发明的清蛋白融合蛋白治疗，预防或改善疾病，病症或病症的方法。

2. 发明申请

WO2010150007A3 RECONFIGURABLE VEHICLE POWER AND SIGNAL DISTRIBUTION SYSTEM 审中-公开
标题翻译：可重新配置车辆电力和信号分配系统
公开(公告)号：WO2010150007A3
公开(公告)日：2011-03-31
申请号：PCT/GB2010051033
申请日：2010-06-22
申请人： GEN DYNAMICS UNITED KINGDOM LTD , MOORE PAUL , HUMPHRIES JAMES
发明人： MOORE PAUL , HUMPHRIES JAMES
IPC分类号： B60R16/02 , B60R16/03
CPC分类号： H02G3/0487 , B60R16/0215 , B60R16/03
摘要： A reconfigurable vehicle power and signal distribution system (10) is disclosed. The system comprises at least one conduit section (11) for housing a first and second power rail (22), and a communication line (20) for communicating signals along the conduit. The system further comprises a transfer hub (27) which enables the transfer of power and signals to a distribution hub that comprises a plurality of terminals for separately providing conditioned power to various system modules of the vehicle. The distribution of power from the distribution hub is dependent on signals received from a control unit via the communication line, which controls the power usage within the vehicle. The system enables the at least one conduit section, transfer hub and distribution hub to be reconfigured according to the topography of the vehicle.
摘要翻译：公开了一种可重构车辆功率和信号分配系统（10）。该系统包括用于容纳第一和第二电力轨道（22）的至少一个导管部分（11）和用于沿着导管传送信号的通信线路（20）。该系统还包括传送集线器（27），其能够将功率和信号传送到分配集线器，分配集线器包括多个端子，用于分别向车辆的各种系统模块提供经过调节的电力。来自分配集线器的电力分配取决于经由通信线路从控制单元接收的信号，其控制车辆内的电力使用。该系统使得能够根据车辆的地形重新配置至少一个管道部分，传送轮毂和分配轮毂。

3. 发明申请

WO9961578A8 TEMPERATURE CONTROL OF INCUBATION VESSELS USING ELECTRICALLY CONDUCTING POLYMERS 审中-公开
标题翻译：使用电导体聚合物进行熔体管的温度控制
公开(公告)号：WO9961578A8
公开(公告)日：2001-05-03
申请号：PCT/GB9901553
申请日：1999-05-17
申请人： SECR DEFENCE , LEE MARTIN ALAN , LESLIE DARIO , MOORE PAUL
发明人： LEE MARTIN ALAN , LESLIE DARIO , MOORE PAUL
IPC分类号： C12M1/02 , G05D23/19 , H05B3/00 , H05B3/14 , B01L7/00
CPC分类号： C12M23/08 , C12M41/22 , H05B3/00 , H05B3/146
摘要： The use of incubation means for the controlled heating of biological materials, said means comprising an electrically conducting polymer connectable to a power supply, said polymer being either contiguous or integral with an incubation vessel, or adapted to be in thermal contact with an incubation vessel. Incubation apparatus including such means and a method for culturing biological materials using them are also described and claimed.
摘要翻译：使用用于受控加热生物材料的温育装置，所述装置包括可连接到电源的导电聚合物，所述聚合物与培养容器相邻或一体，或适于与培养容器热接触。还描述并要求保护包括这些装置的培养装置和使用它们培养生物材料的方法。

4. 发明申请

WO2009076506A3 GAMMA GLUTAMYLCYSTEINE TREATMENT OR PREVENTION OF OXIDATIVE INJURY 审中-公开
标题翻译： GAMMA GLUTAMYLCYSTEINE治疗或预防氧化损伤
公开(公告)号：WO2009076506A3
公开(公告)日：2009-10-29
申请号：PCT/US2008086379
申请日：2008-12-11
申请人： UNIV VANDERBILT , SUMMAR MARSHALL , ASCHNER MICHAEL , CUNNINGHAM GARY , LE TRUC , BARR RICK , MOORE PAUL , ANANTHAKRISHNAN MADHUMITA
发明人： SUMMAR MARSHALL , ASCHNER MICHAEL , CUNNINGHAM GARY , LE TRUC , BARR RICK , MOORE PAUL , ANANTHAKRISHNAN MADHUMITA
IPC分类号： A61K38/05 , A61P39/06
CPC分类号： A61K38/05
摘要： The present invention concerns the ?-glutamylcysteine treatment to reduce oxidative damage caused by ischemia/reperfusion events such as pulmonary hypertension, transplant, cardiac bypass and other surgeries, and trauma. In specific embodiments, preservation methods and apparatuses for preserving tissue for transplantation purposes is provided.
摘要翻译：本发明涉及γ-谷氨酰半胱氨酸治疗以减少由缺血/再灌注事件（例如肺动脉高压，移植，心脏旁路和其他手术）和创伤引起的氧化损伤。在具体实施方案中，提供了用于保持用于移植的组织的保存方法和装置。

5. 发明申请

WO2008001121A8 MOTOR ARRANGEMENT 审中-公开
标题翻译：电机布置
公开(公告)号：WO2008001121A8
公开(公告)日：2009-02-26
申请号：PCT/GB2007002454
申请日：2007-06-29
申请人： MERITOR TECHNOLOGY INC , CAVALLUCCI DENIS , KALSI GURBINDER S , RHODES CHRIS , SPURR NIGEL V , CHONAVEL SYLVAIN REHI , PEATEY DAVID , MOORE PAUL , TOLLEY ROBERT F , OLIVIER JEAN-VINCENT , CLAWLEY ROBERT JAMES
发明人： CAVALLUCCI DENIS , KALSI GURBINDER S , RHODES CHRIS , SPURR NIGEL V , CHONAVEL SYLVAIN REHI , PEATEY DAVID , MOORE PAUL , TOLLEY ROBERT F , OLIVIER JEAN-VINCENT , CLAWLEY ROBERT JAMES
IPC分类号： H02K7/00 , E05B47/00 , E05B65/12 , H02K7/116 , H02K26/00
CPC分类号： H02K26/00 , E05B47/0005 , E05B81/14 , H02K7/00 , H02K7/116 , Y10T292/699
摘要： A motor arrangement having a rotor with a north rotor magnetic pole and a south rotor magnetic pole, the rotor being rotatable about a rotor axis between a first rotor position and a second position, the rotor including a first rotor abutment and a second rotor abutment, a stator having a first stator magnetic pole and a second stator magnetic pole, the stator having a first stator condition in which the first stator magnetic pole is a north stator magnetic pole and the second stator magnetic pole is a south stator magnetic pole, and a second stator condition in which the first stator magnetic pole is a south stator magnetic pole and the second stator magnetic pole is a north stator magnetic pole, the first stator condition corresponding to the first rotor position in which the north rotor magnetic pole is proximate the second stator magnetic pole and the south rotor magnetic pole is proximate the first stator magnetic pole, the second condition corresponding to the second rotor position in which the north rotor magnetic pole is proximate the first stator magnetic pole and the south rotor magnetic pole is proximate the second stator magnetic pole, an output member being rotatable about the rotor axis and having a first output abutment engageable by the first rotor abutment to move the output member in a first rotational direction and having a second output abutment engageable by the second rotor abutment to move the output member in a second rotational direction, the output member being rotatable relative to the rotor to a limited extent defined by the first and second output abutments and the first and second rotor abutments, the motor arrangement further including a first stop to limit movement of the rotor past the first rotor position and a second stop to limit movement of the rotor past the second rotor position.
摘要翻译：一种电动机装置，其具有带有北转子磁极和南转子磁极的转子，所述转子可绕第一转子位置和第二位置之间的转子轴线旋转，所述转子包括第一转子邻接件和第二转子抵接件，具有第一定子磁极和第二定子磁极的定子，所述定子具有第一定子状态，所述第一定子磁极是所述第一定子磁极是北极磁极，所述第二定子磁极是南定子磁极，第二定子条件，其中第一定子磁极是南定子磁极，第二定子磁极是北极磁极，第一定子条件对应于第一转子位置，其中北转子磁极接近第二定子磁极定子磁极和南转子磁极靠近第一定子磁极，第二条件对应于第二转子定位其中北转子磁极靠近第一定子磁极并且南转子磁极接近第二定子磁极，输出构件可围绕转子轴线旋转并具有可由第一转子支座接合的第一输出支座以使输出构件沿第一旋转方向移动并且具有可由第二转子邻接部接合的第二输出支座，以沿第二旋转方向移动输出构件，该输出构件可相对于转子旋转至第一以及第二输出支座以及第一和第二转子支座，马达装置还包括第一止动件，以限制转子超过第一转子位置的运动，以及第二止挡件，以限制转子超过第二转子位置的运动。

6. 发明申请

WO2006087578A8 LATCH ASSEMBLY 审中-公开
标题翻译：拉锁总成
公开(公告)号：WO2006087578A8
公开(公告)日：2008-01-10
申请号：PCT/GB2006000586
申请日：2006-02-17
申请人： MERITOR TECHNOLOGY INC , SPURR NIGEL V , KALSI GURBINDER SINGH , RHODES CHRIS , TOLLEY ROBERT FRANK , PEATEY DAVID , CLAWLEY ROBERT JAMES , MOORE PAUL , OLIVIER JEAN-VINCENT , CHONAVEL SYLVAIN , CAVALLUCCI DENIS
发明人： SPURR NIGEL V , KALSI GURBINDER SINGH , RHODES CHRIS , TOLLEY ROBERT FRANK , PEATEY DAVID , CLAWLEY ROBERT JAMES , MOORE PAUL , OLIVIER JEAN-VINCENT , CHONAVEL SYLVAIN , CAVALLUCCI DENIS
IPC分类号： E05B65/12 , E05B65/20 , E05B65/32
CPC分类号： E05C3/12 , E05B77/28 , E05B81/14 , E05B81/20 , E05B85/26 , E05C3/006 , Y10S292/23 , Y10T70/5903 , Y10T70/70 , Y10T292/1047 , Y10T292/1082
摘要： A latch assembly having a chassis a latch bolt (14) , moveably mounted on the chassis and having a closed position for retaining a striker and an open position for releasing the striker, a pawl (16) having an engaged position at which the pawl is engaged with the latch bolt to hold the latch bolt in the closed position and a disengaged position at which the pawl is disengaged from the latch bolt thereby allowing the latch bolt to move to the open position, an eccentric (54) arrangement defining an eccentric axis and a pawl axis remote from the eccentric axis, with the eccentric being rotatable about the eccentric axis and with the pawl being rotatable about the pawl axis, in which when the pawl moves from the engaged position to the disengaged position the eccentric arrangement rotates in one of a clockwise and anticlockwise direction about the eccentric axis and with the pawl in the engaged position a force applied to the pawl by the latch bolt creates a turning moment on the eccentric arrangement in said one of a clockwise and anticlockwise direction and the eccentric arrangement is prevented from rotating in said one of a clockwise and anticlockwise direction by a moveable abutment.
摘要翻译：一种具有底盘的闩锁组件，闩锁螺栓（14）可移动地安装在底盘上并且具有用于保持撞针的关闭位置和用于释放撞针的打开位置;棘爪（16），其具有接合位置，棘爪与闩锁闩合以将闩锁闩锁在关闭位置，以及脱离位置，在该位置棘爪与闩锁螺栓脱离，从而允许闩锁闩锁移动到打开位置;偏心（54）装置限定偏心轴以及远离偏心轴线的棘爪轴，偏心体能够围绕偏心轴线旋转，并且棘爪可围绕棘爪轴线旋转，其中当棘爪从接合位置移动到脱离位置时，偏心装置以一个沿着偏心轴线的顺时针方向和逆时针方向，并且当棘爪处于啮合位置时，由闩锁螺栓施加到棘爪的力在该偏心轴上产生转动力矩 c布置在顺时针和逆时针方向中的所述一个中，并且通过可移动的邻接件防止偏心装置在顺时针和逆时针方向中的所述一个中旋转。

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