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    • 3. 发明申请
    • RAPID EXCHANGE CATHETER WITH STENT DEPLOYMENT, THERAPEUTIC INFUSION, AND LESION SAMPLING FEATURES
    • 具有静脉注射,治疗性输注和淋巴采样特征的快速交换导管
    • WO03039626A2
    • 2003-05-15
    • PCT/US0235830
    • 2002-11-08
    • HOUSER RUSSELL AHARE WILLIAM D
    • HOUSER RUSSELL AHARE WILLIAM D
    • A61F2/82A61M20060101A61M29/00A61M29/02A61M31/00A61M
    • A61M25/104A61F2/95A61F2/958A61F2002/821A61F2250/0098A61M2025/0183A61M2025/1047A61M2025/1056A61M2025/107A61M2025/1072A61M2025/1095
    • A catheter is insertable into a vessel within a mammalian body. The catheter includes a tubular body, at least one channel extending along the tubular body; and a central lumen. The tubular body includes an exterior surface, a first end and a second end, and defines a length between the first end and the second end. The channel passes between a first opening and a second opening and includes a slot in the tubular body between the channel and the exterior surface of the tubular body such that a tubular member can be passed between the channel and the exterior surface. The slot extends from the the first opening to the second opening and includes a pair of edges. The central lumen extends along the tubular body at least for a portion of the length of the tubular body. The catheter can be used as a rapid exchange catheter, for stent deployment, for drug delivery or therapeutic infusion with or without electoporation, to provide localized heat, to provide ultrasonic visualization and ablation, and to examine for vulnerable plaque. The catheter may have multiple balloons.
    • 导管可插入哺乳动物体内的血管。 导管包括管状体,至少一个沿管状体延伸的通道; 和中央腔。 管状体包括外表面,第一端和第二端,并限定第一端和第二端之间的长度。 通道在第一开口和第二开口之间通过,并且在管状主体中在管状体的外表面之间包括狭槽,使得管状构件能够在通道和外表面之间通过。 狭槽从第一开口延伸到第二开口并且包括一对边缘。 至少对于管状体的长度的一部分,中心腔沿管状体延伸。 导管可以用作快速交换导管,用于支架展开,用于具有或不具有电穿孔的药物递送或治疗性输注,以提供局部热,以提供超声可视化和消融,以及检查易损斑块。 导管可以具有多个气囊。
    • 5. 发明申请
    • PERCUTANEOUS TRANSMYOCARDIAL REVASCULARIZATION (PTMR) SYSTEM
    • PERCUTANEOUS TRANSMYOCARALAL REVASCULARATIONATION(PTMR)系统
    • WO0110287A8
    • 2001-12-06
    • PCT/US0021341
    • 2000-08-04
    • HOUSER RUSSELL A
    • HOUSER RUSSELL A
    • A61B17/00A61B18/14A61B18/18
    • A61B18/1492A61B17/32A61B18/1815A61B2017/00247A61B2018/00011A61B2018/00285A61B2018/00357A61B2018/00392A61B2018/00607A61B2018/00613A61B2018/144A61B2218/002
    • Percutaneous transmyocardial revascularization (PMR) systems are disclosed for creating thin, linear incisions through the endocardium and partially into the myocardium. The systems position a catheter body (10) lengthwise along the endocardial surface and incorporate a cutting mechanism (14) movable radially relative to the catheter body to create one or more thin, linear incisions along one or more windows (16) through the catheter body. Flexible support strands (12) are used to urge each window into intimate contact with the endocardial surface. Each cutting element is adapted to protrude radially outward from the catheter body to contact tissue adjacent each window. The cutting mechanism incorporates a mechanical cutting element or an electrode designed to transmit direct current or RF energy into tissue to simultaneously cut and coagulate tissue. The catheter also can infuse a therapeutic agent directly into the incisions to encourage angiogenesis. The catheter also cuts thin, linear incisions capable of ablating arrhythmia substrates by disrupting electrical propagation through the affected myocardium.
    • 公开了经皮心肌血运重建(PMR)系统,用于通过心内膜产生薄而线性的切口并部分进入心肌。 系统沿着心内膜表面纵向定位导管主体(10)并且包括相对于导管主体径向移动的切割机构(14),以沿着穿过导管主体的一个或多个窗口(16)创建一个或多个薄的线性切口 。 柔性支撑股(12)用于促使每个窗口与心内膜表面紧密接触。 每个切割元件适于从导管主体径向向外突出以接触每个窗口附近的组织。 切割机构包括机械切割元件或设计成将直流电或RF能量传输到组织中以同时切割和凝固组织的电极。 导管还可以将治疗剂直接注入切口以促进血管生成。 导管还切割能够通过破坏通过受影响的心肌的电传播来消融心律失常底物的薄的线性切口。
    • 8. 发明申请
    • RAPID EXCHANGE CATHETER WITH STENT DEPLOYMENT, THERAPEUTIC INFUSION, AND LESION SAMPLING FEATURES
    • 快速交换导管的支架部署,治疗性输注和病变采样功能
    • WO03039626A8
    • 2003-08-21
    • PCT/US0235830
    • 2002-11-08
    • HOUSER RUSSELL AHARE WILLIAM D
    • HOUSER RUSSELL AHARE WILLIAM D
    • A61F2/82A61M20060101A61M29/00A61M29/02A61M31/00A61M
    • A61M25/104A61F2/95A61F2/958A61F2002/821A61F2250/0098A61M2025/0183A61M2025/1047A61M2025/1056A61M2025/107A61M2025/1072A61M2025/1095
    • A catheter is insertable into a vessel within a mammalian body. The catheter includes a tubular body, at least one channel extending along the tubular body; and a central lumen. The tubular body includes an exterior surface, a first end and a second end, and defines a length between the first end and the second end. The channel passes between a first opening and a second opening and includes a slot in the tubular body between the channel and the exterior surface of the tubular body such that a tubular member can be passed between the channel and the exterior surface. The slot extends from the the first opening to the second opening and includes a pair of edges. The central lumen extends along the tubular body at least for a portion of the length of the tubular body. The catheter can be used as a rapid exchange catheter, for stent deployment, for drug delivery or therapeutic infusion with or without electoporation, to provide localized heat, to provide ultrasonic visualization and ablation, and to examine for vulnerable plaque. The catheter may have multiple balloons.
    • 导管可插入哺乳动物体内的血管内。 导管包括管状体,至少一个通道沿着管状体延伸; 和一个中央腔。 管状体包括外表面,第一端和第二端,并限定第一端和第二端之间的长度。 通道在第一开口和第二开口之间通过,并且在通道和管状体的外表面之间的管状体中包括狭槽,使得管状构件可以在通道和外表面之间通过。 狭槽从第一开口延伸到第二开口并且包括一对边缘。 中心内腔至少在管状体的一部分长度上沿着管状体延伸。 导管可用作快速交换导管,用于支架展开,药物输送或有或无电穿孔的治疗性输注,提供局部热量,提供超声波可视化和消融,并检查易损斑块。 导管可以具有多个气球。
    • 9. 发明申请
    • PERCUTANEOUS TRANSMYOCARDIAL REVASCULARIZATION (PTMR) SYSTEM
    • 经皮心肌转复(PTMR)系统
    • WO0110287A2
    • 2001-02-15
    • PCT/US0021341
    • 2000-08-04
    • HOUSER RUSSELL A
    • HOUSER RUSSELL A
    • A61B17/00A61B18/14A61B
    • A61B18/1492A61B17/32A61B18/1815A61B2017/00247A61B2018/00011A61B2018/00285A61B2018/00357A61B2018/00392A61B2018/00607A61B2018/00613A61B2018/144A61B2218/002
    • Percutaneous transmyocardial revascularization (PMR) systems are disclosed for creating thin, linear incisions through the endocardium and partially into the myocardium. The systems position a catheter body (10) lengthwise along the endocardial surface and incorporate a cutting mechanism (14) movable radially relative to the catheter body to create one or more thin, linear incisions along one or more windows (16) through the catheter body. Flexible support strands (12) are used to urge each window into intimate contact with the endocardial surface. Each cutting element is adapted to protrude radially outward from the catheter body to contact tissue adjacent each window. The cutting mechanism incorporates a mechanical cutting element or an electrode designed to transmit direct current or RF energy into tissue to simultaneously cut and coagulate tissue. The catheter also can infuse a therapeutic agent directly into the incisions to encourage angiogenesis. The catheter also cuts thin, linear incisions capable of ablating arrhythmia substrates by disrupting electrical propagation through the affected myocardium.
    • 公开了经皮心肌血运重建(PMR)系统,用于通过心内膜创建细的线性切口并且部分地进入心肌。 系统沿着心内膜表面纵向定位导管主体(10),并且包括相对于导管主体径向移动的切割机构(14),以沿着穿过导管主体的一个或多个窗口(16)形成一个或多个薄的线性切口 。 柔性支撑股线(12)用于促使每个窗口与心内膜表面紧密接触。 每个切割元件适于从导管主体径向向外突出以接触每个窗口附近的组织。 切割机构包含机械切割元件或电极,其被设计成将直流电或RF能量传输到组织中以同时切割和凝结组织。 导管还可以将治疗剂直接注入切口以促进血管生成。 导管还切割薄而线性的切口,能够通过破坏通过受影响的心肌的电传播来消融心律失常底物。