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1. 发明申请

WO2004008891A1 DOCTOR UNDERPANTS 审中-公开
标题翻译：医生资料
公开(公告)号：WO2004008891A1
公开(公告)日：2004-01-29
申请号：PCT/KR2003/001402
申请日：2003-07-16
申请人： HONG, Young-Soo
发明人： HONG, Young-Soo
IPC分类号： A41B9/02
CPC分类号： A41B9/02 , A61H19/32 , A61H2201/1253 , A61H2201/1628 , A61H2201/165
摘要： This invention relates to an inside structure of a male underpants for kinematically moving a penis. The inside structure of the underpants comprises comprises a waistband 110, a penis cord 120 for lifting a lower muscle of the penis positioned between the penis and a scrotum, penis supporting cords 130a, 130b, connected to either side of the penis cord 120, and penis exercising cords 140a, 140b positioned between the penis supporting cords 130a, 130b. The invention has a simple constitution, and thus may be easily manufactured. The invention provides healthful underpants having a pleasant wearing feeling by giving a pleasant stimulation to the lower muscle of the penis and kinematically moving the penis.
摘要翻译：本发明涉及用于运动学运动阴茎的男性内裤的内部结构。内裤的内部结构包括腰带110，用于提升位于阴茎和阴囊之间的阴茎的下部肌肉的阴茎绳120，连接到阴茎绳120的任一侧的阴茎支撑绳130a，130b，以及阴茎锻炼位于阴茎支撑绳130a，130b之间的绳索140a，140b。本发明具有简单的结构，因此可以容易地制造。本发明通过对阴茎的下部肌肉进行愉悦的刺激并且运动地移动阴茎来提供健康的内裤，其具有愉悦的穿着感。

2. 发明申请

WO2003056808A1 DIGITAL CAMERA APPARATUS FURTHER HAVING FUNCTION FOR ACTING AS USB HOST AND DATA TRANSMISSION METHOD THEREOF 审中-公开
标题翻译：具有作为USB主机和数据传输方式进行操作的数字摄像机设备
公开(公告)号：WO2003056808A1
公开(公告)日：2003-07-10
申请号：PCT/KR2002/001422
申请日：2002-07-26
申请人： CORE LOGIC INC. , HWANG, Ki-Soo , SONG, Jun-Kyu , KANG, Young-Tae , KIM, Byong-Su , CHOI, Dong-Soo , KIM, Mun-Kyeom , HONG, Young-Soo , LEE, Suk-Joong , PARK, Sung-Ho
发明人： HWANG, Ki-Soo , SONG, Jun-Kyu , KANG, Young-Tae , KIM, Byong-Su , CHOI, Dong-Soo , KIM, Mun-Kyeom , HONG, Young-Soo , LEE, Suk-Joong , PARK, Sung-Ho
IPC分类号： H04N5/225
CPC分类号： G06F3/005 , H04N1/00204 , H04N5/232 , H04N2201/0041
摘要： A digital camera device having a universal serial bus (USB) host function and a data transmission method therefor are provided. The digital camera device is realized by providing a host function to a usual digital PC camera device. The digital camera device determines a type of USB system for an image processing apparatus connected to the digital camera device and automatically sets an operating mode according to the determined result so that it can communicate with the image processing apparatus. Since the digital camera device can perform direct one-to-one USB communication with the image processing apparatuses, a user can conveniently manipulate images picked up by the digital camera device regardless of a place and the type of USB system for the image processing apparatus.
摘要翻译：提供具有通用串行总线（USB）主机功能的数字照相机装置及其数据发送方法。数码相机设备通过向通常的数字PC相机设备提供主机功能来实现。数字照相机装置确定连接到数字照相机装置的图像处理装置的USB系统的类型，并且根据确定的结果自动设置操作模式，使得其可以与图像处理装置通信。由于数字照相机装置可以与图像处理装置进行直接的一对一USB通信，所以用户可以方便地操纵由数字照相机装置拾取的图像，而不管图像处理装置的USB系统的位置和类型如何。

3. 发明申请

WO2008093912A1 NOVEL ANSAMYCIN DERIVATIVES AND THE METHOD FOR MUTATIONAL BIOSYNTHESIS THEREOF 审中-公开
标题翻译：新的阿萨米辛衍生物及其生物合成的方法
公开(公告)号：WO2008093912A1
公开(公告)日：2008-08-07
申请号：PCT/KR2007/002378
申请日：2007-05-15
申请人： KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY , HONG, Young-Soo , LEE, Jung Joon , LEE, Kyeong , KIM, Woncheol , CAI, Xingfu , LEE, Dongho
发明人： HONG, Young-Soo , LEE, Jung Joon , LEE, Kyeong , KIM, Woncheol , CAI, Xingfu , LEE, Dongho
IPC分类号： C07D225/06
CPC分类号： C07D225/06 , C07C271/12 , C07D313/00 , C12P13/02 , C12P17/08 , C12P17/10
摘要： The present invention relates to a method for producing ansamycin derivatives by using a mutant strain with the mutation of 3-amino-5-hydroxylbenzoic acid (AHBA) biosynthesis gene, more precisely a method for producing novel ansamycin derivatives by adding various types of AHBA analogs to the growth medium of the transformant with the mutation of an AHBA biosynthesis gene. Ansamycin derivatives produced by the method of the present invention have ansamycin-like Hsp90 inhibitory effect, so that it can be effectively used as antibiotics, antifungal agents, antiviral agents, immunosuppressants, anti-inflammatory agents or anticancer agents.
摘要翻译：本发明涉及通过使用具有3-氨基-5-羟基苯甲酸（AHBA）生物合成基因突变的突变菌株来制备安莎霉素衍生物的方法，更准确地说，涉及通过添加各种类型的AHBA类似物来生产新型安莎霉素衍生物的方法转化为具有AHBA生物合成基因突变的转化体的生长培养基。通过本发明方法生产的安沙霉素衍生物具有类霉素样Hsp90抑制作用，因此可有效地用作抗生素，抗真菌剂，抗病毒剂，免疫抑制剂，抗炎剂或抗癌剂。

4. 发明申请

WO2008038964A1 GELDANAMYCIN DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREOF AND AGENT FOR THE PREVENTION AND TREATMENT OF TUMOR CONTAINING THE SAME AS AN ACTIVE INGREDIENT 审中-公开
标题翻译：药物衍生物，其药物可接受的盐，其制备方法和用于预防和治疗含有其作为活性成分的肿瘤的药剂
公开(公告)号：WO2008038964A1
公开(公告)日：2008-04-03
申请号：PCT/KR2007/004645
申请日：2007-09-21
申请人： KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY , HONG, Young-Soo , LEE, Kyeong , LEE, Jung Joon , JIN, Yinlan , KIM, Woncheol
发明人： HONG, Young-Soo , LEE, Kyeong , LEE, Jung Joon , JIN, Yinlan , KIM, Woncheol
IPC分类号： C07D245/06
CPC分类号： C07D225/02
摘要： Disclosed are geldanamycin derivatives of Chemical Formula 1, pharmaceutically acceptable salts thereof, a preparation method thereof, and agents for the preparation and treatment of cancerous diseases, comprising the same as an active ingredient. Having inhibitory activity against the chaperone protein Hsp90, which plays an important role in the growth and metastasis of cancer cells, the geldanamycin derivatives can be used as antibiotics, antifungal agents, anti-viral agents, immuno- suppressors, therapeutics for degenerative nerve diseases, or anti-inflammatory agents, in addition to being applied to the treatment of cancerous diseases. (Chemical Formula 1) (wherein, X, Y, and Z are as defined in the specification)
摘要翻译：公开了化学式1的格尔德霉素衍生物，其药学上可接受的盐，其制备方法和用于制备和治疗癌性疾病的试剂，其包含其作为活性成分。对于在癌细胞的生长和转移中起重要作用的伴侣蛋白Hsp90具有抑制活性，格尔德霉素衍生物可用作抗生素，抗真菌剂，抗病毒剂，免疫抑制剂，退行性神经疾病的治疗剂，或抗炎药，还可用于治疗癌性疾病。（化学式1）（其中，X，Y和Z如说明书中所定义）

5. 发明申请

WO2008038877A1 GELDANAMYCIN DERIVATIVES BY MODIFICATION OF BIOSYNTHETIC GENES 审中-公开
标题翻译：通过修饰生物基因的GELDANAMYCIN衍生物
公开(公告)号：WO2008038877A1
公开(公告)日：2008-04-03
申请号：PCT/KR2007/002054
申请日：2007-04-26
申请人： KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY , HONG, Young-Soo , LEE, Jung Joon , LEE, Kyeong , LEE, Dongho , KIM, Woncheol , SHIN, Jin Chul
发明人： HONG, Young-Soo , LEE, Jung Joon , LEE, Kyeong , LEE, Dongho , KIM, Woncheol , SHIN, Jin Chul
IPC分类号： C07D313/00
CPC分类号： C07D498/08 , C07D225/02 , C12P17/10
摘要： The present invention relates to geldanamycin derivatives, benzoquinone ansamycin, biosynthesized by a genetic modification of Streptomyces hygroscopicus subsp. duamyceticus, in particular, to polyketide genetic mutant (AC3 strain), ge17, ge116 or ge17&ge18 double-gene inactive mutant strain and geldanamycin derivatives, 1Ab, 1Ba, 1Bb, 1Bc, 1Ca, 1Cb, 1Cc 1Cd, and 1Cd, obtained from said mutants among a biosynthetic genes modification of Streptomyces hygroscopicus subsp. duamyceticus. The geldanamycin derivatives of the present invention represents an action of suppressing Hsp90 similarly to geldanamycin, thereby being available for being used as antibiotic agent, antifungal agent, anti-viral agent, immune-suppressive agent, therapeutic agent of neurodegenerative disorders, anti-inflammatory agent or anti-cancer agent and the like.
摘要翻译：本发明涉及通过吸水链霉菌亚种的遗传修饰生物合成的格尔德霉素衍生物苯醌安莎霉素。杜马霉素，特别是从所述的抗氧化剂衍生的聚酮化合物遗传突变体（AC3株），ge17，ge116或ge17＆ge18双基因无活性突变菌株和格尔德霉素衍生物，1Ab，1Ba，1Bb，1Bc，1Ca，1Cb，1Cc 1Cd和1Cd 链霉菌吸水链霉菌亚种的生物合成基因修饰中的突变体 duamyceticus。本发明的格尔德霉素衍生物代表与格尔德霉素类似地抑制Hsp90的作用，因此可用作抗生素，抗真菌剂，抗病毒剂，免疫抑制剂，神经变性疾病的治疗剂，抗炎药或抗癌剂等。

6. 发明申请

WO2008004798A1 COMPOUNDS TEAT INHIBIT HBF-I ACTIVITY, THE METHOD FOR PREPARATION THEREOF AND THE PHARMACEUTICAL COMPOSITION CONTAINING THEM AS AN EFFECTIVE COMPONENT 审中-公开
标题翻译：化合物抑制HBF-1活性，其制备方法和含有有效成分的药物组合物
公开(公告)号：WO2008004798A1
公开(公告)日：2008-01-10
申请号：PCT/KR2007/003216
申请日：2007-07-03
申请人： KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY , LEE, Jung Joon , LEE, Jeong-Hyung , LEE, Kyeong , HONG, Young-Soo , SHANTHAVEERAPPA, B.K. , JIN, Yinlan , KIM, Jin Hwan , JIN, Xuejun
发明人： LEE, Jung Joon , LEE, Jeong-Hyung , LEE, Kyeong , HONG, Young-Soo , SHANTHAVEERAPPA, B.K. , JIN, Yinlan , KIM, Jin Hwan , JIN, Xuejun
IPC分类号： C07C271/28
CPC分类号： C07C237/42 , C07C235/24 , C07C255/60 , C07C271/42 , C07C307/02 , C07C311/46 , C07C317/40 , C07C2603/74 , C07D213/38 , C07D213/75 , C07D213/79 , C07D213/80 , C07D213/81 , C07D235/12 , C07D257/04 , C07D263/56 , C07D307/52 , C07D401/12 , C07D403/12 , C07D405/12 , C07D413/12
摘要： Disclosed herein are an HIF-I inhibitor, a method for the preparation thereof, and a pharmaceutical composition comprising the same as an active ingredient The BDDF-I inhibitor shows anticancer activity thanks to the inhibition activity against HIF-I, a transcription factor which plays an important role in the growth and metastasis of cancer, but not to general cytotoxicity. Thus, the HIF-inhibitor and a pharmaceutically acceptable salt thereof can be used as a therapeutic for various cancers such as liver cancer, stomach cancer and breast cancer. Also, the compound having inhibition activity against HDDF-I is useful in the treatment of diabetic retinopathy and arthritis, which are aggravated by HEF-l-mediated VEGF expression.
摘要翻译：本文公开了HIF-1抑制剂，其制备方法和包含其的药物组合物作为活性成分BDDF-1抑制剂由于对HIF-1的抑制活性显示抗癌活性，HIF-1是一种转录因子在癌症的生长和转移中起重要作用，但不是一般的细胞毒性。因此，HIF抑制剂及其药学上可接受的盐可以用作各种癌症如肝癌，胃癌和乳腺癌的治疗剂。此外，具有对HDDF-1的抑制活性的化合物可用于治疗由HEF-1介导的VEGF表达加重的糖尿病性视网膜病变和关节炎。

7. 发明申请

WO2002074110A1 HEALTH UNDERPANTS 审中-公开
标题翻译：健康服务
公开(公告)号：WO2002074110A1
公开(公告)日：2002-09-26
申请号：PCT/KR2001/000336
申请日：2001-03-05
申请人： HONG, Young-Soo
发明人： HONG, Young-Soo
IPC分类号： A41B9/02
CPC分类号： A41B9/02
摘要： Disclosed is a health underwear allowing a mass production by simplifying the construction thereof. The underwear comprises a body (100) having a waist band (110), a fabric panel (120), and a leg gripping band (130), and a healthy mechanism detachable to the waist band and having a penis wire (210), scrotum wires (220a and 220b), penis training wires (230a and 230b), penis supporting wires (250a and 250b), actuating force transmitting members (240a and 240b), and reverse guide wires (260a and 260b). With the construction, the health underwear has a simple construction, and is a help to men suffering from sexual problems.
摘要翻译：公开了通过简化其构造允许批量生产的健康内衣。所述内衣包括具有腰带（110），织物面板（120）和腿部抓持带（130）的主体（100），以及可拆卸到所述腰带并具有阴茎线（210）的健康机构，阴茎线（220a和220b），阴茎训练线（230a和230b），阴茎支撑线（250a和250b），致动力传递部件（240a和240b）以及反向导丝（260a和260b）。随着施工，保健内衣的施工简单，是对性问题的男人的帮助。

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