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1. 发明申请

WO2012165914A2 NOVEL DIPHENYLMETHANE DERIVATIVES AS SGLT2 INHIBITORS 审中-公开
标题翻译：新型二苯甲基衍生物作为SGLT2抑制剂
公开(公告)号：WO2012165914A2
公开(公告)日：2012-12-06
申请号：PCT/KR2012/004366
申请日：2012-06-01
申请人： GREEN CROSS CORPORATION , CHOI, Soongyu , SONG, Kwang-Seop , LEE, Suk Ho , KIM, Min Ju , SEO, Hee Jeong , PARK, Eun-Jung , KONG, Younggyu , PARK, So Ok , KANG, Hyunku , JUNG, Myung Eun , LEE, Kinam , KIM, Hyun Jung , LEE, Jun Sung , LEE, Min Woo , KIM, Mi-Soon , HONG, Dong Ho , KANG, Misuk
发明人： CHOI, Soongyu , SONG, Kwang-Seop , LEE, Suk Ho , KIM, Min Ju , SEO, Hee Jeong , PARK, Eun-Jung , KONG, Younggyu , PARK, So Ok , KANG, Hyunku , JUNG, Myung Eun , LEE, Kinam , KIM, Hyun Jung , LEE, Jun Sung , LEE, Min Woo , KIM, Mi-Soon , HONG, Dong Ho , KANG, Misuk
IPC分类号： A61K31/357 , A61K31/343 , A61K31/35 , A61K31/015 , A61P3/00
CPC分类号： C07D309/10 , C07D405/10 , C07D405/14 , C07D407/04 , C07D407/10 , C07D407/14 , C07D409/04 , C07D409/10 , C07D409/14 , C07D411/10 , C07D413/04 , C07D413/10 , C07D413/12 , C07D413/14
摘要： The present invention relates to a compound with a diphenylmethane moiety having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney, and a pharmaceutical composition comprising the same as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly diabetes. The present invention also provides a method for preparing the compound, and a method for preventing or treating metabolic disorders, particularly diabetes, by using the compound.
摘要翻译：本发明涉及具有对存在于肠和肾中的钠依赖性葡萄糖协同转运蛋白2（SGLT2）具有抑制活性的二苯基甲烷部分的化合物和包含其作为活性成分的药物组合物，其可用于预防或治疗代谢紊乱，特别是糖尿病。本发明还提供了一种制备该化合物的方法，以及通过使用该化合物来预防或治疗代谢紊乱，特别是糖尿病的方法。

2. 发明申请

WO2011005052A2 NOVEL ARYLPIPERAZINE-CONTAINING IMIDAZOLE 4-CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 审中-公开
标题翻译：新颖的含有阿维菌素的咪唑烷四羧酰胺衍生物和包含其的药物组合物
公开(公告)号：WO2011005052A2
公开(公告)日：2011-01-13
申请号：PCT/KR2010/004479
申请日：2010-07-09
申请人： GREEN GROSS CORPORATION , LEE, Jinhwa , SEO, Hee Jeong , KANG, Suk Youn , PARK, Eun-Jung , KIM, Min Ju , LEE, Suk Ho , KIM, Jong Yup , KIM, Jeongmin , JUNG, Myung Eun , KIM, Hyun Jung , KIM, Mi-Soon , HAN, Ho Kyun , AHN, Kwang Woo , LEE, Min Woo , LEE, Ki-Nam , PAE, Ae Nim , PARK, Woo-Kyu
发明人： LEE, Jinhwa , SEO, Hee Jeong , KANG, Suk Youn , PARK, Eun-Jung , KIM, Min Ju , LEE, Suk Ho , KIM, Jong Yup , KIM, Jeongmin , JUNG, Myung Eun , KIM, Hyun Jung , KIM, Mi-Soon , HAN, Ho Kyun , AHN, Kwang Woo , LEE, Min Woo , LEE, Ki-Nam , PAE, Ae Nim , PARK, Woo-Kyu
IPC分类号： C07D403/12 , A61K31/497 , A61P25/24
CPC分类号： C07D417/14 , A61K31/496 , C07D233/88 , C07D401/12 , C07D403/06 , C07D405/04
摘要： A novel arylpiperazine-containing imidazole 4-carboxamide derivative or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same as an active ingredient for preventing or treating a depressive disorder are provided.
摘要翻译：提供了一种新型含芳基哌嗪的咪唑-4-甲酰胺衍生物或其药学上可接受的盐，以及包含其作为预防或治疗抑郁障碍的活性成分的药物组合物。

3. 发明申请

WO2010147430A3 NOVEL C-ARYL GLUCOSIDE SGLT2 INHIBITORS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 审中-公开
公开(公告)号：WO2010147430A3
公开(公告)日：2010-12-23
申请号：PCT/KR2010/003958
申请日：2010-06-18
申请人： GREEN CROSS CORPORATION , LEE, Jinhwa , LEE, Suk Ho , SEO, Hee Jeong , KIM, Min Ju , KANG, Suk Youn , KIM, Jeongmin , LEE, Sung-Han , JUNG, Myung Eun , SON, Eun Jung , LEE, Junwon , SONG, Kwang-Seop , KIM, Mi-Soon
发明人： LEE, Jinhwa , LEE, Suk Ho , SEO, Hee Jeong , KIM, Min Ju , KANG, Suk Youn , KIM, Jeongmin , LEE, Sung-Han , JUNG, Myung Eun , SON, Eun Jung , LEE, Junwon , SONG, Kwang-Seop , KIM, Mi-Soon
IPC分类号： C07D417/10 , C07D417/14 , C07D405/10 , A61P3/10 , A61K31/433
摘要： A novel C-aryl glucoside compound, or a pharmaceutically acceptable salt or a prodrug thereof having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney; and a pharmaceutical composition comprising the same as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly, diabetes, are provided.

4. 发明申请

WO2011159067A2 THIAZOLE DERIVATIVES AS SGLT2 INHIBITORS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 审中-公开
标题翻译：作为SGLT2抑制剂和包含其的药物组合物的噻唑衍生物
公开(公告)号：WO2011159067A2
公开(公告)日：2011-12-22
申请号：PCT/KR2011/004273
申请日：2011-06-10
申请人： GREEN CROSS CORPORATION , LEE, Jinhwa , KIM, Jeongmin , LEE, Suk Ho , LEE, Junwon , SONG, Kwang-Seop , PARK, Eun-Jung , KIM, Min Ju , SEO, Hee Jeong , LEE, Sung-Han , SON, Eun Jung , KIM, Jong Yup , KANG, Suk Youn , KONG, Younggyu
发明人： LEE, Jinhwa , KIM, Jeongmin , LEE, Suk Ho , LEE, Junwon , SONG, Kwang-Seop , PARK, Eun-Jung , KIM, Min Ju , SEO, Hee Jeong , LEE, Sung-Han , SON, Eun Jung , KIM, Jong Yup , KANG, Suk Youn , KONG, Younggyu
IPC分类号： C07D417/14 , C07D309/10 , C07D417/10 , A61K31/427 , A61K31/351 , A61P3/10
CPC分类号： C07H7/04 , C07D309/10 , C07D417/10 , C07D417/14 , C07D493/10 , C07H17/02
摘要： The present invention relates to a novel compound with thiazole ring having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney, and a pharmaceutical composition comprising the same as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly diabetes.
摘要翻译：本发明涉及一种具有对存在于肠和肾中的钠依赖性葡萄糖协同转运蛋白2（SGLT2）具有抑制活性的噻唑环的新型化合物，以及包含其作为活性成分的药物组合物，其可用于预防或治疗代谢紊乱，特别是糖尿病。

5. 发明申请

WO2010038948A3 ARYLPIPERAZINE-CONTAINING PYRROLE 3-CARBOXAMIDE DERIVATIVES FOR TREATING DEPRESSIVE DISORDERS 审中-公开
公开(公告)号：WO2010038948A3
公开(公告)日：2010-04-08
申请号：PCT/KR2009/005415
申请日：2009-09-23
申请人： GREEN CROSS CORPORATION , LEE, Jinhwa , KANG, Suk Youn , PARK, Eun-Jung , SONG, Kwang-Seop , KIM, Min Ju , SEO, Hee Jeong , LEE, Suk Ho , KIM, Jeongmin , PAE, Ae Nim , PARK, Woo-Kyu
发明人： LEE, Jinhwa , KANG, Suk Youn , PARK, Eun-Jung , SONG, Kwang-Seop , KIM, Min Ju , SEO, Hee Jeong , LEE, Suk Ho , KIM, Jeongmin , PAE, Ae Nim , PARK, Woo-Kyu
IPC分类号： C07D403/14 , C07D403/12 , A61K31/496 , A61K31/495 , A61P25/24
摘要： The present invention relates to novel arylpiperazine-containing pyrrole 3-carboxamide derivatives of formula (I) or a pharmaceutically acceptable salt thereof which is useful for preventing or treating depressive disorders. The present invention also provides a method for preparing the arylpiperazine-containing pyrrole 3-carboxamide derivatives or the pharmaceutically acceptable salt thereof, a pharmaceutical composition containing same, and a method for preventing or treating depressive disorders.

6. 发明申请

WO2012173410A2 NOVEL C-ARYL ANSA SGLT2 INHIBITORS 审中-公开
标题翻译：新型C-ARYL ANSA SGLT2抑制剂
公开(公告)号：WO2012173410A2
公开(公告)日：2012-12-20
申请号：PCT/KR2012/004703
申请日：2012-06-14
申请人： GREEN CROSS CORPORATION , KIM, Min Ju , LEE, Suk Ho , CHOI, Soongyu
发明人： KIM, Min Ju , LEE, Suk Ho , CHOI, Soongyu
IPC分类号： A61K31/357 , A61K31/35 , C07D493/14 , A61P3/10 , A61P3/00
CPC分类号： C07D491/056 , C07D493/08
摘要： The present invention relates to a novel C-aryl ansa compound having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney, and a pharmaceutical composition comprising the same as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly diabetes. The present invention also provides a method for preparing the compound, and a method for preventing or treating metabolic disorders, particularly diabetes, by using the compound.
摘要翻译：本发明涉及一种对肠和肾中存在的钠依赖性葡萄糖协同转运蛋白2（SGLT2）具有抑制活性的新型C芳基ansa化合物，以及包含其作为活性成分的药物组合物，其可用于预防或治疗代谢紊乱，特别是糖尿病。本发明还提供了一种制备该化合物的方法，以及通过使用该化合物来预防或治疗代谢紊乱，特别是糖尿病的方法。

7. 发明申请

WO2011025336A2 WHITE POROUS POLYESTER FILM AND PREPARATION METHOD THEREOF 审中-公开
标题翻译：白色多孔聚酯薄膜及其制备方法
公开(公告)号：WO2011025336A2
公开(公告)日：2011-03-03
申请号：PCT/KR2010/005849
申请日：2010-08-30
申请人： SKC CO., LTD. , KIM, Min Ju , JU, Jae Seog , SHIN, Heon Jung
发明人： KIM, Min Ju , JU, Jae Seog , SHIN, Heon Jung
IPC分类号： C08J5/18 , C08L67/00 , C08K5/3492 , C08K7/16
CPC分类号： C08J5/18 , C08J2367/02 , C08K3/01 , C08K5/3492 , C08L67/02 , C08L2666/02
摘要： A white porous film, which comprises a polyester resin, a hydroxyphenyl triazine-based UV stabilizing agent, amorphous polymer particles which are immiscible with a polyester, first inorganic particles having a refractive index of 2.0 or more, and second inorganic particles having a refractive index of 1.7 or less, has improved optical properties such as whiteness, masking ability, reflectance, and UV-resistance and it is useful as a functional film for use in printing, labeling, electronics, and display applications.
摘要翻译：一种白色多孔膜，其包含聚酯树脂，羟基苯基三嗪基UV稳定剂，与聚酯不混溶的无定形聚合物颗粒，折射率为2.0以上的第一无机颗粒和具有折射率的第二无机颗粒为1.7以下，具有改善了白度，掩蔽能力，反射率，抗紫外线性等光学特性，作为印刷，贴标，电子，显示应用中使用的功能膜是有用的。

8. 发明申请

WO2008082152A1 POLYIMIDE FILM WITH IMPROVED ADHESIVENESS 审中-公开
标题翻译：具有改善粘性的聚酰亚胺膜
公开(公告)号：WO2008082152A1
公开(公告)日：2008-07-10
申请号：PCT/KR2007/006882
申请日：2007-12-27
申请人： SKC CO., LTD. , KIM, Do Kyoung , KIM, Min Ju
发明人： KIM, Do Kyoung , KIM, Min Ju
IPC分类号： C08J5/18
CPC分类号： C08J5/18 , C08G73/1064 , C08G73/1067 , C08J2379/08 , H05K1/0346
摘要： A polyimide film derived from a polyamic acid resin obtained by copolymerization of an aromatic acid dianhydride component and an aromatic diamine component comprising 5 to 60 mole% of a diamine having a sulfonyl group in its main chain based on the total mole of the aromatic diamine component has a Young¡¯s modulus of 4.5 to 9.5 GPa, a tensile strength at breakage of 15 to 30 kgf/§±, a tensile elongation at breakage of 25 to 60%, and a ratio of the tensile strength at breakage to the yield strength of less than 1.35. Therefore, the polyimide film exhibits improved adhesive strength with metal, flexural endurance and punching characteristics, and thus, can be efficiently used in electronic devices.
摘要翻译：一种聚酰亚胺膜，其衍生自通过芳族二酸酐组分和芳族二胺组分共聚而得到的聚酰胺酸树脂，所述芳族二胺组分包含5-60％（摩尔）主链中具有磺酰基的二胺，基于芳族二胺组分杨氏模量为4.5〜9.5GPa，断裂拉伸强度为15〜30kgf /§±，断裂时的拉伸伸长率为25〜60％，断裂时的拉伸强度与屈服强度的比强度小于1.35。因此，聚酰亚胺膜与金属的粘合强度提高，弯曲耐久性和冲孔特性，因此可以有效地用于电子装置。

9. 发明申请

WO2008093971A1 CROSSLINKED POLYIMIDE FILM AND PROCESS FOR PREPARATION THEREOF 审中-公开
标题翻译：交联聚酰亚胺薄膜及其制备方法
公开(公告)号：WO2008093971A1
公开(公告)日：2008-08-07
申请号：PCT/KR2008/000504
申请日：2008-01-28
申请人： SKC CO., LTD. , LEE, Jung Gyu , WON, Dong Young , KIM, Do Kyoung , KIM, Min Ju
发明人： LEE, Jung Gyu , WON, Dong Young , KIM, Do Kyoung , KIM, Min Ju
IPC分类号： C08J5/18
CPC分类号： C08J5/18 , C08J2379/08 , H05K1/0346
摘要： The present invention is directed to a crosslinked polyimide film whose main repeating units is derived from a polyamic acid crosslinked with a sulphonic acid having two or more functional groups selected from -CO- and -O-, and a process for the preparation thereof. The crosslinked polyimide film according to the present invention is excellent in thermal dimensional stability and heat resistance, and has a low moisture absorbability and moisture expansion coefficient, and a high elastic modulus. Therefore, the crosslinked polyimide film of the present invention can be effectively used as an electronic material, for example for a flexible circuit board.
摘要翻译：本发明涉及一种交联聚酰亚胺膜，其主要重复单元衍生自具有两个或更多个选自-CO - 和-O-的官能团的磺酸交联的聚酰胺酸及其制备方法。本发明的交联聚酰亚胺膜的热尺寸稳定性和耐热性优异，吸湿性和湿膨胀系数低，弹性模量高。因此，本发明的交联聚酰亚胺膜可以有效地用作电子材料，例如用于柔性电路板。

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