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1. 发明申请

WO2004026371A3 METHOD AND APPARATUS FOR SELECTIVE DRUG INFUSION VIA AN INTRAAORTIC FLOW DIVERTER DELIVERY CATHETER 审中-公开
标题翻译：通过流体流量输送管选择性药物输注的方法和装置
公开(公告)号：WO2004026371A3
公开(公告)日：2004-09-02
申请号：PCT/US0329743
申请日：2003-09-22
申请人： FLOWMEDICA INC , VALENCIA AURELIO , ABOYTES RICARDO , ELKINS JEFFREY M , GOODSON HARRY B IV , PATEL SAMIR R , BALL CRAIG A , GREENAN TREVOR M , KESTEN RANDY J , KRAMER ANDREW K , PAYNE SAM G , PESOTCHINSKY SOPHIA , ROSENTHAL MICHAEL H
发明人： VALENCIA AURELIO , ABOYTES RICARDO , ELKINS JEFFREY M , GOODSON HARRY B IV , PATEL SAMIR R , BALL CRAIG A , GREENAN TREVOR M , KESTEN RANDY J , KRAMER ANDREW K , PAYNE SAM G , PESOTCHINSKY SOPHIA , ROSENTHAL MICHAEL H
IPC分类号： A61M20060101 , A61M25/00
CPC分类号： A61M25/1002 , A61M25/00 , A61M25/0074 , A61M25/0082 , A61M25/04 , A61M29/02 , A61M39/06 , A61M2025/0073 , A61M2025/1052
摘要： A local renal delivery system includes a flow isolation assembly and a local injection assembly. The flow isolation assembly in one mode is adapted to isolate only a partial flow region along the outer circumference along the aorta wall such that fluids inject there are maintained to flow substantially into the renal arteries. Various types of flow isolation assemblies and local injection assemblies are described.
摘要翻译：局部肾递送系统包括流动隔离组件和局部注射组件。在一种模式中的流动隔离组件适于仅沿着沿着主动脉壁的外周隔离部分流动区域，使得在其中注入的流体被维持以基本上流入肾动脉。描述了各种类型的流动隔离组件和局部注射组件。

2. 发明申请

WO2004032791A3 METHOD AND APPARATUS FOR SELECTIVE MATERIAL DELIVERY VIA AN INTRA-RENAL CATHETER 审中-公开
标题翻译：通过内镜导管选择性材料输送的方法和装置
公开(公告)号：WO2004032791A3
公开(公告)日：2004-07-01
申请号：PCT/US0329744
申请日：2003-09-22
申请人： FLOWMEDICA INC , GOODSON HARRY B IV , ELKINS JEFFREY M , PATEL SAMIR R , VALENCIA AURELIO , ABOYTES RICARDO , BALL CRAIG A , KESTEN RANDY J , KRAMER ANDREW K , PAYNE SAM G , PESOTCHINSKY SOPHIA , ROSENTHAL MICHAEL H
发明人： GOODSON HARRY B IV , ELKINS JEFFREY M , PATEL SAMIR R , VALENCIA AURELIO , ABOYTES RICARDO , BALL CRAIG A , KESTEN RANDY J , KRAMER ANDREW K , PAYNE SAM G , PESOTCHINSKY SOPHIA , ROSENTHAL MICHAEL H
IPC分类号： A61B20060101 , A61F20060101 , A61F2/06 , A61M25/00 , A61M25/01 , A61M25/04 , A61M25/10 , A61M25/14 , A61M29/02
CPC分类号： A61M25/04 , A61M25/0029 , A61M25/0054 , A61M25/0147 , A61M25/0152 , A61M29/02 , A61M39/06 , A61M2025/0008 , A61M2025/0034 , A61M2025/0037 , A61M2025/0161 , A61M2025/0188 , A61M2025/1004 , A61M2025/1047 , A61M2025/1052
摘要： Two renal delivery members have two distal ports (212, 214) that are adapted to be positioned within two renal arteries via their corresponding renal ostia at unique location along an abdominal aortic wall.
摘要翻译：两个肾递送构件具有两个远端口（212,214），其适于通过其沿着腹主动脉壁的独特位置处的相应肾口位于两个肾动脉内。

3. 发明申请

WO2004034767A8 APPARTUS AND METHOD FOR INSERTING AN INTRA-AORTA CATHETER THROUGH A DELIVERY SHEATH 审中-公开
标题翻译：通过输送管插入入口导管的方法和方法
公开(公告)号：WO2004034767A8
公开(公告)日：2004-07-01
申请号：PCT/US0329585
申请日：2003-09-22
申请人： FLOWMEDICA INC , ELKINS JEFFREY M , GOODSON HARRY B IV , MAGUIRE MARK A , VALENCIA AURELIO , PATEL SAMIR R
发明人： ELKINS JEFFREY M , GOODSON HARRY B IV , MAGUIRE MARK A , VALENCIA AURELIO , PATEL SAMIR R
IPC分类号： A61M25/00 , A61M25/01 , A61M25/06 , A61M31/00
CPC分类号： A61M25/0043 , A61M25/0662 , A61M39/06
摘要： An introducer system delivers therapy locally to a renal system in a patient. A proximal coupler assembly is coupled to an introducer sheath that delivers multiple devices simultaneously into a location within an abdominal aorta associated with first and second renal artery ostia. The coupler assembly has a network of branch lumens arranged to allow for smooth slideable engagement of multiple coupled devices without substantial interference therebetween. A first branch lumen typically introduces a percutaneous translumenal interventional device such as an angiography or guiding catheter into the introducer sheath and is substantially aligned with a longitudinal axis of the sheath. One or more other branch lumen are off-axis from the longitudinal axis by about 30 degrees or less and introduce components of a bilateral renal delivery assembly into the introducer sheath in conjunction with the other device. Novel insertion devices are provided to coordinate the coupling of the multiple devices.
摘要翻译：导引器系统将局部给予患者的肾系统治疗。近端联接器组件联接到导引器鞘，其将多个装置同时输送到与第一和第二肾动脉口相关联的腹主动脉内的位置。耦合器组件具有布置成允许多个耦合器件的平滑可滑动接合而没有实质干涉的分支腔的网络。第一分支腔通常将经皮腔内介入装置（例如血管造影或引导导管）引入导引鞘，并且基本上与鞘的纵向轴线对准。一个或多个其它分支腔从纵向轴线偏离约30度或更小，并且将双侧肾递送组件的组分与另一装置结合引入导引鞘中。提供了新的插入装置来协调多个装置的耦合。

4. 发明申请

WO2004034767A3 CATHETER SYSTEM FOR RENAL THERAPY 审中-公开
标题翻译：用于肾功能治疗的导管系统
公开(公告)号：WO2004034767A3
公开(公告)日：2005-12-29
申请号：PCT/US0329585
申请日：2003-09-22
申请人： FLOWMEDICA INC , ELKINS JEFFREY M , GOODSON HARRY B IV , MAGUIRE MARK A , VALENCIA AURELIO , PATEL SAMIR R
发明人： ELKINS JEFFREY M , GOODSON HARRY B IV , MAGUIRE MARK A , VALENCIA AURELIO , PATEL SAMIR R
IPC分类号： A61M25/00 , A61M25/01 , A61M25/06 , A61M31/00
CPC分类号： A61M25/0043 , A61M25/0662 , A61M39/06
摘要： An introducer system (350) delivers therapy locally to a renal system in a patient. A proximal coupler assembly (360) is coupled to an introducer sheath (376) that delivers multiple devices simultaneously into a location within an abdominal aorta associated with first and second renal artery ostia. The coupler assembly (360) has a network of branch lumens arranged to allow for smooth slideable engagement of multiple coupled devices without substantial interference therebetween. A first branch lumen typically introduces a percutaneous translumenal interventional device such as an angiography or guiding catheter into the introducer sheath (376) and is substantially aligned with a longitudinal axis of the sheath (376). One or more other branch lumen are off-axis from the longitudinal axis by about 30 degrees or less and introduce components of a bilateral renal delivery assembly into the introducer sheath (376 ) in conjunction with the other device. Novel insertion devices are provided to coordinate the coupling of the multiple devices.
摘要翻译：引导器系统（350）将治疗局部递送到患者的肾脏系统。近端联接器组件（360）联接到导引器鞘（376），其将多个装置同时传送到与第一和第二肾动脉口相关联的腹主动脉内的位置。耦合器组件（360）具有布置成允许多个耦合器件的平滑可滑动接合而不产生实质干涉的分支腔的网络。第一分支管腔通常将经皮腔内介入装置（例如血管造影或引导导管）引入导引器鞘（376）并且基本上与护套（376）的纵向轴线对准。一个或多个其它分支腔从纵向轴线偏离约30度或更小，并且将双侧肾递送组件的组分与另一装置结合引入导引鞘（376）。提供了新的插入装置来协调多个装置的耦合。

5. 发明申请

WO2004107965A2 SYSTEMS AND METHODS FOR PERFORMING BI-LATERAL INTERVENTIONS OR DIAGNOSIS IN BRANCHED BODY LUMENS 审中-公开
标题翻译：在分支体内实施双向干预或诊断的系统和方法
公开(公告)号：WO2004107965A2
公开(公告)日：2004-12-16
申请号：PCT/US2004008573
申请日：2004-03-19
申请人： FLOWMEDICA INC , PATEL SAMIR , GOODSON HARRY B IV , ELKINS JEFFREY M , BALL CRAIG A , MATHUR VANDANA S
发明人： PATEL SAMIR , GOODSON HARRY B IV , ELKINS JEFFREY M , BALL CRAIG A , MATHUR VANDANA S
IPC分类号： A61B20060101 , A61F20060101 , A61F2/06 , A61M25/00 , A61M25/01 , A61M25/04 , A61M25/10 , A61M25/14 , A61M29/02 , A61B
CPC分类号： A61M25/04 , A61M25/0029 , A61M25/0054 , A61M25/0147 , A61M25/0152 , A61M29/02 , A61M39/06 , A61M2025/0008 , A61M2025/0034 , A61M2025/0037 , A61M2025/0161 , A61M2025/0188 , A61M2025/1004 , A61M2025/1047 , A61M2025/1052
摘要： Bifurcated delivery assemblies provide bilateral access to first and second branch lumens extending from a main body space or lumen in a patient. One or more interventional devices are combined with the delivery assemblies for delivery s into one or both of the branch lumens. Bilateral renal stenting or embolic protection procedures are performed using the combination del ivery/interventional device assemblies. Fluids may also be injected or aspirated from the assemblies. A bifurcated catheter has a first fluid port located on one bifurcation branch, a second fluid port located on a second branch of the bifurcation, and a third fluid port positioned so as to be located within a vena cava when the first and second ports are positioned bilaterally within first and second renal veins.
摘要翻译：分叉输送组件提供从患者的主体空间或内腔延伸的第一和第二分支腔的双向通路。一个或多个介入装置与输送组件组合以用于输送到一个或两个分支腔。双侧肾支架置入或栓塞保护程序是使用组合式/介入装置组件进行的。流体也可以从组件注入或吸出。分叉导管具有位于一个分叉分支上的第一流体端口，位于分叉的第二分支上的第二流体端口和位于第一和第二端口定位的位于腔静脉内的第三流体端口在第一和第二肾静脉内双侧。

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